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| 1 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 2 | Human adenovirus(HAdV)infection in children with acute respiratory tract infections in Guangzhou,China,2010–2021:a molecular epidemiology study显示文摘Background Human adenovirus(HAdV)infection can cause a variety of diseases.It is a major pathogen of pediatric acute respiratory tract infections(ARIs)and can be life-threatening in younger children.We described the epidemiology and subtypes shifting of HAdV among children with ARI in Guangzhou,China.Methods We conducted a retrospective study of 161,079 children diagnosed with acute respiratory illness at the Guangzhou Women and Children’s Medical Center between 2010 and 2021.HAdV specimens were detected by real-time PCR and the hexon gene was used for phylogenetic analysis.Results Before the COVID-19 outbreak in Guangzhou,the annual frequency of adenovirus infection detected during this period ranged from 3.92%to 13.58%,with an epidemic peak every four to fve years.HAdV demonstrated a clear seasonal distribution,with the lowest positivity in March and peaking during summer(July or August)every year.A signifcant increase in HAdV cases was recorded for 2018 and 2019,which coincided with a shift in the dominant HAdV subtype from HAdV-3 to HAdV-7.The latter was associated with a more severe disease compared to HAdV-3.The average mortality proportion for children infected with HAdV from 2016 to 2019 was 0.38%but increased to 20%in severe cases.After COVID-19 emerged,HAdV cases dropped to 2.68%,suggesting that non-pharmaceutical interventions probably reduced the transmission of HAdV in the community.Conclusion Our study provides the foundation for the understanding of the epidemiology of HAdV and its associated risks in children in Southern China. | Yi Chen Tao Lin Chang‑Bing Wang Wan‑Li Liang Guang‑Wan Lian Mark Zanin Sook‑San Wong Xin‑Gui Tian Jia‑Yu Zhong Ying‑Ying Zhang Jia‑Hui Xie Ling‑Ling Zheng Fei‑Yan Chen Run Dang Ming‑Qi Zhao Yi‑Yu Yang Rong Zhou Bing Zhu | 2022 | World Journal of Pediatrics2022，18，8： | 5 |
| 3 | Design and Synthesis of a Highly Stable Six-hydrogen-bonded Serfassembly Yellowish Green Electroluminescent Molecular Duplex显示文摘This paper describes the design, synthesis and characterization of a hydrogen-bonded molecular duplex with 1,8-naphthalimide fluorescent pendants. The two oligoamide molecular strands, with complementary hydrogen bond sequences of DDADAA and AADADD, can form an ultra stable self-assembly duplex. Its molecular structure was confirmed by 1H NMR and ESI-MS, and its photoluminescence properties were determined. The resulting duplex exhibited a dramatically enhanced photoluminescence (PL) quantum efficiency of 63.7% compared to the corresponding 1,8-naphthalimide segment (32.4%), suggesting that the formation of the duplex with larger molecular weight could successfully inhibit the quenching of the fluorescent pendant. This novel duplex is a prospective candidate for new electroluminescent emitter. | Guang Dong LEI Yi YI Zhi Yun LU Ming Gui XIE | 2005 | Chinese Chemical Letters2005，16，9： | 3 |
| 4 | Improved One-pot Synthesis of 4,6-Dihydroxyisophthalic Acid and 2,3-Dihydroxyterephthalic Acid显示文摘An improved method for the large-scale preparation of 4,6-dihydroxyisophthalic acid and 2,3-dihydroxyterephthalic acid has been developed. Compared to the previous procedures, this new process requires much lower CO2 pressure of 0.3 Mpa and shorter reaction time, thus providing a convenient access for large-scale synthesis. The yield is high (93% and 65%, respectively), and the oxidation of phenol is nearly inhibited, neither decolorization nor further chromatographic purification is required. | Guang Dong LEI Li Xin LI Zhi Yun LU Ming Gui XIE | 2005 | Chinese Chemical Letters2005，16，8： | 3 |
| 5 | Red Electroluminescence and Photoluminescence from Novel Binuclear Europium Complex with Squaric Acid Ligand显示文摘A novel binuclear europium b-diketone complex with squaric acid ligand was synthesized for the first time. Its structure was elucidated by IR, UV, and Elemental Analysis. Red light emitting diode (LED) was fabricated by using the novel europium complex as an emitting layer, tris(8-quinolinolate) aluminum (III) (Alq3) as an electron-transporting layer, N, N’-diphenyl-N, N’-(3-methylphenyl)-1,1’-biphenyl-4,4’-diamine (TPD) as a hole-transporting layer. A cell structure of indium-tin-oxide/TPD/Eu-complex/Alq3/Mg: Ag was employed. Red electroluminescence was observed at room temperature with dc bias voltage of 2 V in this cell. Red emission peaks at about 613 nm with maximum luminance of over 106 cd/m2. Compared with the EL luminance from those europium complexes reported before, one from the Eu-complex is best in the same cells. | Wei Guo ZHU Xiao Qiang WEI Mei Xiang ZHU Zhi Yun LU Bo LIANG Ming Gui XIE De Qiang ZHANG Yong QIU | 2001 | Chinese Chemical Letters2001，12，10： | 2 |
| 6 | Novel fluorene-carzazole-based conjugated copolymers containing pyrazoline and benzothiazole segments for blue light-emitting materials显示文摘有 pyrazoline 和 benzothiazole 单位的一系列新奇 fluorene-carbazole-based 共聚物通过联合反应的铃木成功地被综合。分子的结构和这些聚合物的热性质被英尺红外, 1H NMR, DSC 和 TGA 描绘。GPC 结果显示分子的重量(Mw ) 和这些聚合物的多分散性在范围的重量一般水准(12,000 14,000 ) 并且(1.8 2.0 ) 分别地。二产生聚合物有高光致发光量效率暗示他们可能为聚合物正在答应候选人轻射出的二极管(PLEDs ) 。 | Hao Chen Xing Xu He Gang Yan Xian Rong Cai Ying Li Qing Jiang Ming Gui Xie | 2007 | Chinese Chemical Letters2007，18，12： | 1 |
| 7 | Studies on the Technology and Mechanism of Laser Photoinduced Alignment of Liquid Crystal显示文摘IntroductionTheanisotropyofliquidcrystalsmakesitpossibletobemadeintomanykindsofelec-tro-opticdevices.WhenthethicknessoftheLCc... | HE Yu e WANG Zhan qi and XIE Ming gui (Department of Chemistry, Sichuan University, Chengdu, 610064) CAI Bang wei and BI Guo jiang (Department of Opt Electronic & Science, Sichuan University, Chengdu, 610064) | 1998 | Chemical Research in Chinese Universities1998，14，4： | 1 |
| 8 | Synthesis and phosphorescent properties of two novel iridium (Ⅲ) complexes bearing bulky tert-butyl substituents显示文摘The synthesis and phosphorescence properties of two novel Ir(Ⅲ)complexes bearing tert-butyl substituents,bis(4-tert-butyl-2- phenylbenzothiozolato-N,C2′)iridium(Ⅲ)(acetylacetonate)[(tbt)2Ir(acac)]and bis(4-tert-butyl-1-phenyl-1H-benzimidazolato- N,C2′)iridium(Ⅲ)(acetylacetonate)[(tpbi)2Ir(acac)],are reported,their molecular structures are confirmed by1H NMR,ESI-MS and elementary analysis.Photoluminescence(PL)studies revealed that they can emit strong green and orange phosphorescence in high quantum yields.Compared to their prototypes lacking of tert-butyl substituents,the two novel iridium(Ⅲ)complexes both have shorter lifetimes and improved or nearly similar PL quantum efficiencies,implying that the exciton quenching is inhibited effectively when molecular steric hindrance increases.The two chelates have great potential to be used as electrophosphorescent materials. | Rong Huang~a Xiao Qiang Wei~(a,b) Tai Ping Zhang~a Zhi Yun Lu~(a,*) Ming Gui Xie~a a College of Chemistry,Sichuan University,Chengdu 610064,China b School of Optic-electronic Information,University of Electronic Science and Technology of China,Chengdu 610054,China | 2007 | Chinese Chemical Letters2007，18，9： | 1 |
| 9 | Applied research of shaped charge technology显示文摘 | Yu Chuan Tong Yanjin Yan Chengli Li Fabo Gui Yulin Zhang Ming Wang Bingren Xie Panhai Li Liangzong | 1999 | International Journal of Impact Engineering1999，，： | 1 |
| 10 | Synthesis of Coronene Using Microwave Irradiation显示文摘Using microwave irradiation, perylene was obtained from 3,4,9,10-perylenetetracar- boxylic dianhydride with copper powder in boiling quinoline. With the same method, 1,12- benzoperylene was synthesized from 1, 12-benzoperylene-1, 2-dicarboxylic anhydride, and coronene was prepared from coronene-1, 2- dicarboxylic anhydride with good yield. Through Dields-Alder reaction, 1, 12-benzoperylene-1, 2-dicarboxylic anhydride and coronene-1,2- dicarboxylic anhydride were also prepared using microwave irradiation. | Bing YANG, Ying LI*, Ming Gui XIE Faculty of Chemistry, Sichuan University, Chengdu 610064 | 2003 | Chinese Chemical Letters2003，14，8： | 1 |
| 11 | Red Mechanoluminescence and Photoluminescence from Novel Europium Complexes显示文摘Two new binuclear (europium and lanthanum) β-diketone complexes Eu0.9La0.1(TTA)3Phen and Eu0.5La0.5(TTA),Phen in which Phen is 1,10-phenanthroline, TTA is an anion of thenoyltrifluoroacetone (HTTA) were synthesized for the first time. They showed intense photoluminescence (PL) and mechanoluminescence (ML), and had their maximum PL and ML spectra peaked at 6 13.5 nm with half bandwidth of 10 nm respectively. Their PL and ML intensity were obviously stronger than these from Eu(TTA)3Phen. It is considered that binuclear (europium and lanthanum) β-diketones complexes are promising ML and PL materials. | Wei Guo ZHU Tong Suo YUAN Xiao Qiang WEI Zhi Yun LU Yan HUANG Yu LIU Qiang PENG Ming Gui XIE(Department of Chemistry Sichuan University, Chengdu 610064 Department of Chemistry, Xiangtan University, Xiangtan 411105 Department of Biochemistry Qiongzho | 2000 | Chinese Chemical Letters2000，11，7： | 1 |
| 12 | Synthesis of Multidentate Squaraines显示文摘To search for more better sensitizer of organic solar cell,a series of multidentate squaraines (Sq1-6) were synthesized, the structures were determined by elemental analysis,IR, UV-vis,^1H NMR and MS spectroscopies. The squaraing have good solubility in polar solvents such as EtOH,CH3COCH3,CHCl3, etc. as well as strong absorption band over 600-700 nm spectral range. | Ying LI*, Ming Gui XIE The Faculty of Chemistry, Sichuan University, Chengdu 610064 | 2002 | Chinese Chemical Letters2002，13，6： | 1 |
| 13 | Synthesis of Pyrazolines Used as Blue Organic Electroluminescence Materials显示文摘Three kinds of pyrazolines were designed and synthesized. Their structures were elucidated by IR, 1HNMR, MS, UV and elemental analysis. Their luminescent properties were determined, which indicated that they had strong blue fluorescent properties. One of them was designed to have good film formation. All the three kinds of pyrazolines can be used as blue organic electroluminescence materials (OELMs). | Zhi Yun LU Wei Guo ZHU Qing JIANG Ming Gui XIE (Department of Chemistry. Sichuan University, Chengdu 610064) | 1999 | Chinese Chemical Letters1999，10，8： | 0 |
| 14 | Synthesis of a Novel Blue- light- emitting Polymer Material Bearing Coumarin Pendants显示文摘A novel blue luminescent polymer bearing coumarin pendants was prepared. Its luminescent properties were determined indicating that it had strong blue fluorescent properties and good film formation ability. This novel polymer can be used as a blue organic electroluminescent material (OELM) in organic electroluminescent devices. | Zhi Yun LU, Tong Suo YUAN, Yan Lai CHEN, Xiao Qiang WEI, Wei Guo ZHU, Ming Gui XIE* Department of Chemistry, Sichuan University, Chengdu 610064 | 2002 | Chinese Chemical Letters2002，13，7： | 0 |
| 15 | PARM: a New QSAR Research Method Based on Genetic Algorithm显示文摘Based on Walters’ GERM[3](Genetic Evolved Receptor Model) algorithm. an improved algorithm PARM(Pseudo Atomic Receptor Model) was put forward.PARM uses combination of genetic algorithm and cross-validation technique to produce atomic-level pseudo receptor model, based on a set of known structure-activity relationship. This algorithm has been applied to one system and afforded reasonable results. | Hong Ming CHEN Jia Ju ZHOU Tian Rui REN Gui Rong XIE (Laboratory of Computer Chemsitry, Institute of Chemical Metallurgy Chinses Academy of Sciences, Beijing 100080) | 1997 | Chinese Chemical Letters1997，8，11： | 0 |
| 16 | SYNTHESIS OF DIAZA CROWN ETHER CHIRAL LIQUID CRYSTAL显示文摘A chiral liquid crystal crown ether containing diaza-18-crown-6 was synthesized with the help of CPK atomic model and in the meantime a nonchiral liquid crystal crown ether of alike structure was also synthesized for comparison, indicating that only the former was asymmetric. The present work represents the first attempt of the investigation in chiral liquid crystal crown ether, thus providing basis for further research into problems as such. | Ming Gui XIE~*, Jun QIN, Zi Lun HU, Hua Ming ZHAO Department of Chemistry, Sichuan University, Chengdu 610064. | 1992 | Chinese Chemical Letters1992，3，10： | 0 |
| 17 | SYNTHESIS OF AZA-CROWN-ETHER CHOLESTERIC LIQUID CRYSTALS显示文摘Five aza-crown-ethers were synthesized and four of them shown to have cholesteric liquid crystalline properties. Their properties relevant to cholesteric liquid crystal were determined by DSC and the textures. The type of cholesteric mesomorphic azacrown ether have not been reported so far. | Ming Gui XIE~a,Shi Kui LIU~b, Gang LIU~c and Jiang Ling LI~d ~aDepartment of Chemistry, Sichuan University, Chengdu, 610064. ~bChengdu Institute of Organic Chemistry, Academia Sinica, 610015. ~cChengdu Institute of Chemical Engineering Research and Design, Chengdu, 610061 ~dEnviromental Monitoring Station of Wuhou District, Chengdu, 610041. | 1992 | Chinese Chemical Letters1992，3，10： | 0 |
| 18 | Synthesis and characterization of novel low band-gap polymers containing squaraine units显示文摘小说基于有 2,5 二度的 squaric 酸结合了聚合物[在主要的链联合起来的(E)-N-alkylpyrrol-2-ylvinyl]-3-alkylthiophene (PVTVP ) 成功地通过 polycondensation 反应在好收益被综合。他们的分子的结构被英尺红外和 1H NMR 描绘。他们在普通器官的溶剂,由热 gravimetric 分析的好热稳定性和高分子的重量有好溶解度。他们的光性质被紫外力吸收系列在 CH2Cl2 答案调查,结果显示了宽广、强壮的显示出的所有这些混合物光谱对 900 nm 的从 200 nm 的回答,作为器官的塑料为申请建议他们的潜力太阳能电池。 | Er Fu Huo Jiang Yong Wu Bao Feng Song Ying Li Qing Jiang Ming Gui Xie | 2007 | Chinese Chemical Letters2007，18，12： | 0 |
| 19 | Synthesis and Fluorescent Properties of New Binuclear Europiumβ-Diketone Chelates Eu_mY_(1-m)(TTA)_3phen as Red Electroluminescent Materials显示文摘A new type of binuclear europlum β-diketone chelates Eum Y1-m(TTA)3 phen (0≤m≤1) and the influence of the proportion of Y on fluorescence intensity of the Eu-complexes were studied. It was found the proportion of Y3+ could affect the fluorescence properties and the film formation seriously. only m≥0.5.Y3+ could increase the luminescent intensity and improve the film formalion. As a resull. three new binuclear europium β-diketone chelales consisted of Eu, Y1-m (TTA)3phen (m=0.9. 0.7 and 0.5) were designed and synthesized. Their structures were elucidated by IR. UV. DSC and Elementary Analysis. Their PL properties were studied. The results showed that the three binuclear europium β-diketone chelates had better PL properties and film formation than Eu(TYA)3phen. They could emit sharply red light, and fluorescenl wavelength of them was all at 613nm (half bandwidth 10nm). They can be used as red organic electroluminescent materials (OELMs) in organic electrolminescent devices (OELDS). | Wei Guo ZHU Xiao Qiang WEI Zhi Yun LU Qing JIANG Ming Gui XIE(Department of Chemistry. Sichuan University. Chengdu 610064) | 1999 | Chinese Chemical Letters1999，10，7： | 0 |
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