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46篇 您的检索式:作者名="WANG Ming Xuan"
    题名 作者 年代 出处 被引量
1Evaluation of the Prostate Imaging Reporting and Data System for Magnetic Resonance Imaging Diagnosis of Prostate Cancer in Patients with Prostate-specific Antigen 〈20 ng/ml显示文摘Xuan Wang Jian-Ye Wang Chun-Mei Li Ya-Qun Zhang Jian-Long Wang Ben Wan Wei Zhang Min Chen Sa-Ying Li Gang Wan Ming Liu 2016Chinese Medical Journal2016,,12:13
2Molecular characteristics and structure–activity relationships of food-derived bioactive peptides显示文摘Peptides are functional active fragments of proteins which can provide nutrients needed for human growth and development,and they also have unique physiological activity characteristics relative to proteins.Bioactive peptides contain a great deal of development potential.More specifically,food-derived bioactive peptides have the advantages of a wide variety of sources,unique structures,high efficiency and safety,so they have broad development prospects.This review provides an overview of the current advances regarding the preparation,functional characteristics,and structure–activity relationships of food-derived bioactive peptides.Moreover,the prospects for the future development and application of food-derived bioactive peptides are discussed.This review may provide a better understanding of foodderived bioactive peptides,and some constructive inspirations for further research and applications in the food industry.YANG Fu-jia CHEN Xu HUANG Mu-chen YANG Qian CAI Xi-xi CHEN Xuan DU Ming HUANG Jian-lian WANG Shao-yun 2021Journal of Integrative Agriculture2021,20,9:9
3Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes.MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 2020Biomedical and Environmental Sciences2020,33,12:8
4Lung-protective Ventilation in Patients with Brain Injury: A Multicenter Cross-sectional Study and Questionnaire Survey in China显示文摘Xu-Ying Luo Ying-Hong Hu Xiang-Yuan Cao Yan Kang Li-Ping Liu Shou-Hong Wang Rong-Guo Yu Xiang-You Yu Xia Zhang Bao-Shan Li Zeng-Xiang Ma Yi-Bing Weng Heng Zhang De-Chang Chen Wei Chen Wen-Jin Chen Xiu-Mei Chen Bin Du Mei-Li Duan Jin Hu Yun-Feng Hoang Gui-Jun Jia Li-Hong Li Yu-Min Liang Bing-Yu Qin Xian-Dong Wang Jian Xiong Li-Mei Yan Zheng-Ping Yang Chen-Ming Dong Dong-Xin Wang Qing-Yuan Zhan Shuang-Lin FU Lin Zhao Qi-Bing Huang Ying-Guang Xie Xiao-Bo Huang Guo-Bin Zhang Wang-Bin Xu Yuan Xu YaLing Liu He-Ling Zhao Rong-Qing Sun Ming Sun Qing-Hong Cheng Xin Qu Xiao-Feng Yang Ming Xu Zhong-Hua Shi Han Chen Xuan He Yan-Lin Yang Guang-Qiang Chen Xiu-Mei Sun Jian-Xin Zhou 2016Chinese Medical Journal2016,,14:6
5Correlation between the expression of thrombospondin-1 and neovascularization in mucoepidermoid carcinoma显示文摘背景研究人员最近证明了 thrombospondin-1 (TSP-1 ) 在调整 neovascularization 有重要功能。然而,它是否禁止或加速 neovascularization,仍然是争论的。我们在 mucoepidermoid 癌关于在 TSP-1 和 vascularization 之间的关联发现了很少报告。在这研究,在 mucoepidermoid 癌的 TSP-1 的分发和表示被调查。我们也分析了( 1 )在 TSP-1 和 microvessel 密度( MVD )的表示之间的关联作为 neovascularization 活动的指示物,并且( 2 )在 mucoepidermoid carcinoma.Method ( 1 )的下的 xenotransplanted 模型的 neovascularization 和肿瘤生长上的 TSP-1 的效果 TSP-1 和 MVD 的表示的地点和紧张被 streptavidin-peroxidase ( SP )的方法在外科以后在 mucoepidermoid 癌的 45 种情况中分析 immunohistochemistry ;并且(2 ) recombinant 人 thrombospondin-1 (rhTSP-1 ) 一个星期被注射两次因为在在下的 xenotransplanted 肿瘤的肿瘤附近的五个连续星期在裸体老鼠 mucoepidermoid 癌当模特儿。每个星期,肿瘤尺寸被测量,以便拉 mucoepidermoid 癌,和 MVD 的 xenotransplanted 肿瘤模特儿的生长曲线是 TSP-1 蛋白质的积极表示是的 measured.Results (1 )57.78%(26/45 ) 。为 TSP-1 的最积极的染色在癌症房间的细胞质被发现,当染色的一些发生在细胞外的矩阵时。在 mucoepidermoid 癌的 45 种情况中的吝啬的 MVD 是 58.17 獲映牯琠敨搠灥桴漠 ? 湩慶楳湯 ? 潦浲 ? 景朠潲瑷 ? 瀠瑡潨潬楧慣? 牧摡 ? 愠摮搠来敲 ?景搠晩敦敲瑮慩楴 吗?YANG Sen WANG Xiao-yi GUO Li-juan TANG Xiu-fa GAO Qing-hong XUAN Ming ZHANG Qiang TAN Ke WEN Yu-ming WANG Chang-mei XU Rui-an CAO Yu-tang 2008Chinese Medical Journal2008,,19:4
6Effectiveness of Using Mean Corpuscular Volume and Mean Corpuscular Hemoglobin for Beta-thalassemia Carrier Screening in the Guangdong Population of China显示文摘Beta(β)-thalassemia is one of the most common hemoglobinopathies worldwide,creating major public health problems and social burdens in many regions.Screening forβ-thalassemia carriers is crucial for controlling this condition.To investigate the?effectiveness?of?mean?corpuscular?volume?(MCV)and mean corpuscular hemoglobin(MCH)for screeningβ-thalassemia,retrospective data were analyzed for 6,779β-thalassemia carriers subjected to genetic testing following thalassemia screening in Guangdong province between January 2018 and December 2019.GU Heng WANG Yong Xia DU Meng Xuan XU Shan Shan ZHOU Bing Yi LI Ming Zhen 2021Biomedical and Environmental Sciences2021,34,8:4
7Effect of creatine phosphate sodium on miRNA378,miRNA378* and calumenin mRNA in adriamycin-injured cardiomyocytes显示文摘Objective: To investigate the effect of creatine phosphate sodium(sodium phosphocreatine) on miRNA378, miRNA378* and calumenin m RNA in adriamycin-injured suckling mouse myocardium. Methods: The suckling mouse myocardium of primary culture were randomly divided into control group, adriamycin group and treatment group. To identify the suckling mouse myocardium, Smooth muscle actin-α(α-SMA) was monitored by immunohistochemical method. Cardiac function was evaluated by transthoracic echocardiography. The mRNA change of miRNA378, miRNA378* and calumenin m RNA were detected by quantitative real-time PCR. The expression of calumenin and GRP78 were identified by western blot. Results: Mitochondrial damage and vacuolization were found in adriamycin-induced suckling mouse myocardium compared with control group, while creatine phosphate sodium could reduce this phenomenon. Compared with the control group, the mRNA of miRNA378, miRNA378* and calumenin in adriamycin group was reduced, while creatine phosphate sodium could increase this phenomenon. The expression of calumenin and GRP78 were decreased after adriamycin treatment in suckling mouse myocardiums, creatine phosphate sodium increased the expression of calumenin and GRP78. Conclusion: The results of this experiment might be closely related to the effects of that creatine phosphate sodium reduced the pathological mechanism of suckling mouse myocardium with myocarditis caused by adriamycin.Miao YU Zhi-hui HE Li-ying XUAN Xiao-tong SHAN Jie LONG Jing-yi FENG Yu WANG Ming ZHAO 2016中国应用生理学杂志2016,32,6:4
8Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration显示文摘Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity.Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question.A replication-coupled DNA methylation maintenance model was proposed decades ago,but some observations suggest that a replication-uncoupled maintenance mechanism exists.However,the capacity and the underlying molecular events of replication-uncoupled maintenance are unclear.By measuring maintenance kinetics at the single-molecule level and assessing mutant cells with perturbation of various mechanisms,we found that the kinetics of replication-coupled maintenance are governed by the UHRF1–Ligase 1 and PCNA–DNMT1 interactions,whereas nucleosome occupancy and the interaction between UHRF1 and methylated H3K9 specifically regulate replication-uncoupled maintenance.Surprisingly,replication-uncoupled maintenance is sufficiently robust to largely restore the methylome when replication-coupled maintenance is severely impaired.However,solo-WCGW sites and other CpG sites displaying aging-and cancer-associated hypomethylation exhibit low maintenance efficiency,suggesting that although quite robust,mitotic inheritance of methylation is imperfect and that this imperfection may contribute to selective hypomethylation during aging and tumorigenesis.Xuan Ming Zhuqiang Zhang Zhuoning Zou Cong Lv Qiang Dong Qixiang He Yangyang Yi Yingfeng Li Hailin Wang Bing Zhu 2020Cell Research2020,30,11:4
9Cognitive magnetic resonance imaging-ultrasound fusion transperineal targeted biopsy combined with randomized biopsy in detection of prostate cancer显示文摘BACKGROUND Prostate cancer(PCa)is one of the most common cancers among men.Various strategies for targeted biopsy based on multiparametric magnetic resonance imaging(mp-MRI)have emerged,which may improve the accuracy of detecting clinically significant PCa in recent years.AIM To investigate the diagnostic efficiency of a template for cognitive MRIultrasound fusion transperineal targeted plus randomized biopsy in detecting PCa.METHODS Data from patients with an increasing prostate-specific antigen(PSA)level but less than 20 ng/mL and at least one lesion suspicious for PCa on MRI from December 2015 to June 2018 were retrospectively analyzed.All patients underwent cognitive fusion transperineal template-guided targeted biopsy followed by randomized biopsy outside the targeted area.A total of 127 patients with complete data were included in the final analysis.A multivariable logistic regression analysis was conducted,and a two-sided P<0.05 was considered statistically significant.RESULTS PCa was detected in 66 of 127 patients,and 56 cases presented clinically significant PCa.Cognitive fusion targeted biopsy alone detected 59/127 cases of PCa,specifically 52/59 cases with clinically significant PCa and 7/59 cases with clinically insignificant PCa.A randomized biopsy detected seven cases of PCa negative on targeted biopsy,and four cases had clinically significant PCa.PSA density(OR:1.008,95%CI:1.003-1.012,P=0.001;OR:1.006,95%CI:1.002-1.010,P=0.004)and Prostate Imaging-Reporting and Data System(PI-RADS)scores(both P<0.001)were independently associated with the results of cognitive fusion targeted biopsy combined with randomized biopsy and targeted biopsy alone.CONCLUSION This single-centered study proposed a feasible template for cognitive MRIultrasound fusion transperineal targeted plus randomized biopsy.Patients with higher PSAD and PI-RADS scores were more likely to be diagnosed with PCa.Cheng Pang Miao Wang Hui-Min Hou Jian-Yong Liu Zhi-Peng Zhang Xuan Wang Ya-Qun Zhang Chun-Mei Li Wei Zhang Jian-Ye Wang Ming Liu 2021World Journal of Clinical Cases2021,9,36:3
10Implementing the communication for development strategy to improve knowledge and coverage of measles vaccination in western Chinese immunization programs:a before-and-after evaluation显示文摘Background:Communication for Development(C4D)is a strategy promoted by the United Nations Children’s Fund to foster positive and measurable changes at the individual,family,community,social,and policy levels of society.In western China,C4D activities have previously been conducted as part of province-level immunization programs.In this study,we evaluated the association of C4D with changes in parental knowledge of immunization services,measles disease,and measles vaccine,and changes in their children’s measles vaccine coverage.Methods:From April 2013 to April 2014,C4D activities were implemented as part of provincial immunization programs in the Inner Mongolia,Guangxi,Chongqing,Guizhou,Tibet,Shaanxi,Gansu,Ningxia,and Qinghai provinces.We used a before-and-after study design and employed face-to-face interviews to assess changes in parental knowledge and vaccination coverage.Results:We surveyed 2107 households at baseline and 2070 households after 1 year of C4D activities.Following C4D,95%of caregivers were aware of the vaccination record check requirement for entry into kindergarten and primary school;80%of caregivers were aware that migrant children were eligible for free vaccination;more than 70%of caregivers knew that measles is a respiratory infectious disease;and 90%of caregivers knew the symptoms of measles.Caregivers’willingness to take their children to the clinic for vaccination increased from 51.3%at baseline to 67.4%in the post-C4D survey.Coverage of one-dose measles-containing vaccine(MCV)increased from 83.8%at baseline to 90.1%after C4D.One-dose MCV coverage was greater than 95%in the Guangxi,Shaanxi,and Gansu provinces.Two-dose MCV coverage increased from 68.5 to 77.6%.House-to-house communication was the most popular C4D activity among caregivers(91.6%favoring),followed by posters and educational talks(64.8 and 49.9%favoring).Conclusions:C4D is associated with increased caregiver knowledge about measles,increased willingness to seek immunization services for their children,and increased measles vaccination coverage.Tailored communication strategies based on insights gained from these analyses may be able to increase vaccination coverage in hard-to-reach areas.C4D should be considered for larger scale implementation in China.Ming Lu Yao-Zhu Chu Wen-Zhou Yu Robert Scherpbier Yu-Qing Zhou Xu Zhu Qi-Ru Su Meng-Juan Duan Xuan Zhang Fu-Qiang Cui Hua-Qing Wang Yi-Biao Zhou Qing-Wu Jiang 2017Infectious Diseases of Poverty2017,6,1:3
11Overview of the Solar Polar Orbit Telescope Project for Space Weather Mission显示文摘The Solar Polar ORbit Telescope(SPORT) project for space weather mission has been under intensive scientific and engineering background studies since it was incorporated into the Chinese Space Science Strategic Pioneer Project in 2011.SPORT is designed to carry a suite of remote-sensing and in-situ instruments to observe Coronal Mass Ejections(CMEs),energetic particles,solar high-latitude magnetism,and the fast solar wind from a polar orbit around the Sun.The first extended view of the polar regions of the Sun and the ecliptic enabled by SPORT will provide a unique opportunity to study CME propagation through the inner heliosphere,and the solar high-latitude magnetism giving rise to eruptions and the fast solar wind.Coordinated observations between SPORT and other spaceborne/ground-based facilities within the International Living With a Star(ILWS) framework can significantly enhance scientific output.SPORT is now competing for official selection and implementation during China's 13 th Five-Year Plan period of 2016-2020.XIONG Ming LIU Ying LIU Hao LI Baoquan ZHENG Jianhua ZHANG Cheng XIA Lidong ZHANG Hongxin RAO Wei CHEN Changya SUN Weiying WU Xia DENG Yuanyong HE Han JIANG Bo WANG Yuming WANG Chuanbing SHEN Chenglong ZHANG Haiying ZHANG Shenyi YANG Xuan SANG Peng WU Ji 2016空间科学学报2016,36,3:3
12On s-semipermutable Subgroups of Finite Groups显示文摘假定 G 是一个有限的组, H 是 G 的亚群。我们说 H 是在 G 的 s-semipermutable 如果为 G 与的任何 Sylow p 亚群 G p 的 H G p = G p H (p, |H|)= 1。我们在有限的组的结构上调查 s-semipermutable 亚群的影响。一些最近的结果被概括并且统一。关键词 s-semipermutable 亚群 - 概括恰当的亚群 - p-nilpotent 组 - 浸透的形成先生(2000 ) 题目分类 20D10 - 20D20 由中国(资助号码 10871210 ) 的国家自然科学基础支持了,广东省(资助号码 06023728 )Yang Ming LI Xuan Li HE Yan Ming WANG 2010Acta Mathematica Sinica,English Series2010,26,11:3
13The Influence of Diabetes, Hypertension, and Hyperlipidemia on the Onset of Age-Related Macular Degeneration in North China: The Kailuan Eye Study显示文摘Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for AMD.Methods A population-based cross-sectional epidemiologic study was conducted involving 14,440 individuals.We assessed the prevalence of dry and wet AMD in diabetic and non-diabetic subjects and analyzed the risk factors for AMD.Results The prevalence of wet AMD in diabetic and non-diabetic patients was 0.3%and 0.5%,respectively,and the prevalence of dry AMD was 17%and 16.4%,respectively.The prevalence of wet AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 0.5%,0.3%,0.2%,and 0.7%,respectively.The prevalence of dry AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 16.6%,16.2%,15.2%,and 17.2%,respectively.Age,sex,body mass index,and use of hypoglycemic drugs or lowering blood pressure drugs were corrected in the risk factor analysis of AMD.Diabetes,diabetes/hypertension,diabetes/hyperlipidemia,and diabetes/hypertension/hyperlipidemia were analyzed.None of the factors analyzed in the current study increased the risk for the onset of AMD.Conclusion There was no significant difference in the prevalence of wet and dry AMD among diabetic and non-diabetic subjects.Similarly,there was no significant difference in the prevalence of wet and dry AMD among subjects with hypertension and hyperlipidemia.Diabetes co-existing with hypertension and hyperlipidemia were not shown to be risk factors for the onset of dry AMD.ZHANG Yong Peng WANG Ya Xing ZHOU Jin Qiong WANG Qian YAN Yan Ni YANG Xuan YANG Jing Yan ZHOU Wen Jia WANG Ping SHEN Chang YANG Ming LUAN Ya Nan WANG Jin Yuan WU Shou Ling CHEN Shuo Hua WANG Hai Wei FANG Li Jian WAN Qian Qian ZHU Jing Yuan NIE Zi Han CHEN Yu Ning XIE Ying JONAS JB WEI Wen Bin 2022Biomedical and Environmental Sciences2022,35,7:2
14Effects of MCI-186 on intracellular calcium ion concentration and membrane fluidity of hippocampal neurons in a rat model of Alzheimer's disease显示文摘The present study observed the effects of MCI-186 on the intracellular calcium ion concentra-tion ([Ca2+]i) and membrane fluidity of hippocampal neurons in Alzheimer's disease (AD) model rats to validate the neuroprotective effects of MCI-186.Compared with normal and sham-operated rats,the escape latency was obviously prolonged,spanning platform times were obviously reduced,[Ca2+]i was increased,and microviscosity η value was increased in AD rats.MCI-186 at 0.5 mg/mL and 0.2 mg/mL obviously shortened escape latency,increased spanning platform times and decreased [Ca2+]i and microviscosity η values in AD rats at 7 and 17 days after induction of the model.The differences in the above-mentioned indices between normal and MCI-186-treated rats were statistically significant.MCI-186 at 0.2 mg/mL yielded better curative effects than 0.5 mg/mL MCI-186.These findings suggest that MCI-186 improves learning and memory abilities in AD rats by decreasing [Ca2+]i and increasing membrane fluidity of hippocampal neurons.Ming Yu Lei Qin Zhao Wang Xiaohong Lu Ying Zhu Wenhui Leng Xuan Wang 2011Neural Regeneration Research2011,6,29:2
15Author Correction: Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration显示文摘We apologize for the mistake of the fund information in the acknowledgements.The correct information is as follows.This correction does not affect the conclusion of the work.Xuan Ming Zhuqiang Zhang Zhuoning Zou Cong Lv Qiang Dong Qixiang He Yangyang Yi Yingfeng Li Hailin Wang Bing Zhu 2021Cell Research2021,31,3:2
16Site testing campaign for the Large Optical/infrared Telescope of China:overview显示文摘The Large Optical/infrared Telescope(LOT)is a ground-based 12 m diameter optical/infrared telescope which is proposed to be built in the western part of China in the next decade.Based on satellite remote sensing data,along with geographical,logistical and political considerations,three candidate sites were chosen for ground-based astronomical performance monitoring.These sites include:Ali in Tibet,Daocheng in Sichuan and Muztagh-ata in Xinjiang.Up until now,all three sites have continuously collected data for two years.In this paper,we will introduce this site testing campaign,and present its monitoring results obtained during the period between March 2017 and March 2019.Lu Feng Jin-Xin Hao Zi-Huang Cao Jin-Min Bai Ji Yang Xu Zhou Yong-Qiang Yao Jin-Liang Hou Yong-Heng Zhao Yu Liu Teng-Fei Song Li-Yong Liu Jia Yin Hua-Lin Chen Chong Pei Ali Esamdin Lu Ma Chun-Hai Bai Peng Wei Jing Xu Guang-Xin Pu Guo-Jie Feng Xuan Zhang Liang Ming Abudusaimaitijiang Yisikandee Jian-Rong Shi Jian Li Yuan Tian Zheng Wang Xia Wang Xiao-Jun Jiang Jian-Feng Wang Jian-Feng Tian Yan-Jie Xue Jian-Sheng Chen Jing-Yao Hu Zhi-Xia Shen Yun-Ying Jiang 2020Research in Astronomy and Astrophysics2020,20,6:2
17Comparison of Clinical Characteristics and Outcomes of Pediatric and Adult Patients with Coronavirus Disease 2019 in Shenzhen,China显示文摘Objective Here we aimed to investigate the difference in clinical characteristics and outcomes between pediatric and adult patients with COVID-19.Methods A total of 333 consecutive patients with laboratory-confirmed SARS-CoV-2 infection treated in the departments of Internal medicine of Shenzhen Third People’s Hospital from January 11 th to February 10 th,2020 were included.The data were obtained from electronic medical records.The epidemiological data,clinical characteristics,length of hospital stays,and outcomes of pediatric and adult patients were compared.Results Compared with adult patients,pediatric patients had a shorter time of symptom onset to hospitalization than adults[median time,1(IQR,1.0-1.0)d vs.3(IQR,2.0-6.0)d,P<0.001],milder or fewer symptoms,less severe chest CT findings.The clinical severity classification of children was less severe than adults.Up to 15 th March,the end of the follow-up,33(100%)children and 292(97.3%)adult patients had been discharged from hospital.Only 2(0.7%)adult patients died,with an overall case mortality of 0.6%.The median length of hospital stay of pediatric patients was shorter than that of adult patients[19(95%CI:16.6-21.4)d vs.21(95%CI:19.9-22.1)d,P=0.024].Conclusion Pediatric patients with COVID-19 had milder or less clinical symptoms,less evident pulmonary imaging changes,better prognosis,and shorter length of hospital stay.WANG Fang LAI Chang Xiang HUANG Peng Yu LIU Jia Ming WANG Xian Feng TANG Qi Yuan ZHOU Xuan XIAN Wen Jie CHEN Rui Kun LI Xuan LI Zhi Yu LIAO Li Qun HE Qing LIU Lei 2020Biomedical and Environmental Sciences2020,33,12:2
18The impacts of different embolization techniques on splenic artery embolization for blunt splenic injury: a systematic review and meta-analysis显示文摘Background: Splenic artery embolization(SAE) has been an effective adjunct to the Non-operative management(NOM) for blunt splenic injury(BSI). However, the optimal embolization techniques are still inconclusive. To further understand the roles of different embolization locations and embolic materials in SAE, we conducted this system review and meta-analyses.Methods: Clinical studies related to SAE for adult patients were researched in electronic databases, included Pub Med, Embase, Science Direct and Google Scholar Search(between October 1991 and March 2013), and relevant information was extracted. To eliminate the heterogeneity, a sensitivity analysis was conducted on two reduced study sets. Then, the pooled outcomes were compared and the quality assessments were performed using Newcastle-Ottawa Scale(NOS). The SAE success rate, incidences of life-threatening complications of different embolization techniques were compared by χ2 test in 1 st study set. Associations between different embolization techniques and clinical outcomes were evaluated by fixed-effects model in 2 nd study set.Results: Twenty-three studies were included in 1 st study set. And then, 13 of them were excluded, because lack of the necessary details of SAE. The remaining 10 studies comprised 2 nd study set, and quality assessments were performed using NOS. In 1 st set, the primary success rate is 90.1% and the incidence of life-threatening complications is 20.4%, though the cases which required surgical intervention are very few(6.4%). For different embolization locations, there was no obvious association between primary success rate and embolization location in both 1 st and 2 nd study sets(P >0.05). But in 2 nd study set, it indicated that proximal embolization reduced severe complications and complications needed surgical management. As for the embolic materials, the success rate between coil and gelfoam is not significant. However, coil is associated with a lower risk of life-threatening complications, as well as less complications requiring surgical management.Conclusion: Different embolization techniques affect the clinical outcomes of SAE. The proximal embolization is the best option due to the less life-threatening complications. For commonly embolic material, coil is superior to gelfoam for fewer severe complications and less further surgery management.Jing-Jing Rong Dan Liu Ming Liang Qing-Hua Wang Jing-Yang Sun Quan-Yu Zhang Cheng-Fei Peng Feng-Qi Xuan Li-Jun Zhao Xiao-Xiang Tian Ya-Ling Han 2018Military Medical Research2018,5,1:2
19Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China显示文摘Gui‐Rui Yu Xian‐Jin Zhu Yu‐Ling Fu Hong‐Lin He Qiu‐Feng Wang Xue‐Fa Wen Xuan‐Ran Li Lei‐Ming Zhang Li Zhang Wen Su Sheng‐Gong Li Xiao‐Min Sun Yi‐Ping Zhang Jun‐Hui Zhang Jun‐Hua Yan Hui‐Min Wang Guang‐Sheng Zhou Bing‐Rui Jia Wen‐Hua Xiang Ying‐Nian Li Lia 2012Glob Change Biol2012,,3:1
20Site-testing at Muztagh-ata site Ⅰ:ground meteorology and sky brightness显示文摘Site-testing is crucial for achieving the goal of scientific research and analysis of meteorological and optical observing conditions,one of the associated basic tasks.As one of three potential sites to host the 12-meter Large Optical/infrared Telescope(LOT),the Muztagh-ata site,which is located on the Pamir Plateau in Xinjiang,in west China,began its site-testing task in the spring of 2017.In this paper,we firstly start with an introduction to the site and then present a statistical analysis of the ground-level meteorological properties such as air temperature,barometric pressure,relative humidity,and wind speed and direction,recorded by an automatic weather station with standard meteorological sensors for a two-year duration.We also show the monitoring results of sky brightness during this period.Jing Xu Ali Esamdin Jin-Xin Hao Jin-Min Bai Ji Yang Xu Zhou Yong-Qiang Yao Jin-Liang Hou Guang-Xin Pu Guo-Jie Feng Chun-Hai Bai Peng Wei Shu-Guo Ma Abudusaimaitijiang Yisikandee Le-Tian Wang Xuan Zhang Liang Ming Lu Ma Jin-Zhong Liu Zi-Huang Cao Yong-Heng Zhao Lu Feng Jian-Rong Shi Hua-Lin Chen Chong Pei Xiao-Jun Jiang Jian-Feng Wang Jian-Feng Tian Yan-Jie Xue Jing-Yao Hu Yun-Ying Jiang 2020Research in Astronomy and Astrophysics2020,20,6:1
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