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| 1 | 2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma显示文摘The incidence of papillary thyroid carcinoma(PTC)has exponentially increased in recent years.Papillary thyroid microcarcinoma(PTMC)accounts for the majority of the reported cases of PTC.The debates and crucial issues in PTMC management have received researchers'attention.To further improve the clinical management of PTMC in China, | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Li Gao Zhuming Guo Tao Huang Xiaoming Huang Xiaoming Li Yansong Lin Qinjiang Liu Xin Ni Yi Pan Jianwu Qin Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Daiwei Zhao Naisong Zhang ShengZhang Ying Zheng Jingqiang Zhu Dapeng Li Xiangqian Zheng 无 | 2017 | Cancer Biology & Medicine2017，14，3： | 23 |
| 2 | 4-Hydroxybenzyl-substituted amino acid derivatives from Gastrodia elata显示文摘Seven new 4-hydroxybenzyl-substituted amino acid derivatives(1-7), together with 11 known compounds, were isolated from an aqueous extract of the rhizomes of Gastrodia elata Blume.Their structures were determined by spectroscopic and chemical methods. Compounds 1-3 are pyroglutamate derivatives containing 4-hydroxybenzyl units at the N atom and 4-7 are the first examples of natural products with the 4-hydroxybenzyl unit linked via a thioether bond to 2-hydroxy-3-mercaptopropanoic acid(4-6) and 2-hydroxy-4-mercaptobutanoic acid(7), which would be biogenetically derived from cysteine and homocysteine, respectively. The structures of 1 and 2 were verified by synthesis, while the absolute configurations of 4, 5 and 7 were assigned using Mosher's method based on the MPA determination rule of ΔδRS values. The known compound 4-(hydroxymethyl)-5-nitrobenzene-1,2-diol(8) exhibited activity against Fe^(2+)-cysteine induced rat liver microsomal lipid peroxidation with IC_(50) values of 9.99×10^(-6) mol/L. | Qinglan Guo Yanan Wang Sheng Lin Chenggen Zhu Minghua Chen Zhibo Jiang Chengbo Xu Dan Zhang Huailing Wei Jiangong Shi | 2015 | Acta Pharmaceutica Sinica B2015，5，4： | 18 |
| 3 | Three pairs of alkaloid enantiomers from the root of Isatis indigotica显示文摘Three pairs of enantiomerically pure alkaloids with diverse structure features, named isatindigoticoic acid A and epiisatindigoticoic acid A [(—)-1 and(+)-1], phaitanthrin A and epiphaitanthrin A [(—)-2 and(+)-2], and isatindopyrromizol A and epiisatindopyrromizol A [(—)-3and(+)-3], respectively, were isolated from an aqueous extract of the roots of Isatis indigotica. Racemic and scalemic mixtures of these enantiomers were separated by HPLC on a chiral semi-preparative column.Their structures including absolute configurations were determined by extensive spectroscopic analysis in conjunction with the calculation of electronic circular dichroism(ECD) spectra. The enantiomer pairs possess parent structures of 2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid, indolo[2,1-b]quinazolinone, and 3-thioxohexahydro-1H-pyrrolo[1,2-c]imidazol-1-one, respectively. Except for phaitanthrin A[(—)-2] which the configuration was previously undetermined, these compounds are new enantiomeric natural products. | Yufeng Liu Xiaoliang Wang Minghua Chen Sheng Lin Li Li Jiangong Shi | 2016 | Acta Pharmaceutica Sinica B2016，6，2： | 12 |
| 4 | Changes of plasma C-reactive protein in patients with craniocerebral injury before and after hyperbaric oxygenation: A randomly controlled study显示文摘BACKGROUND: Plasma inflammatory factor, such as C-reactive protein, whose content is regarded as a sensitively pathological marked protein and quantitative indexes of central nervous system injury, has been paid more and more attention in clinic. OBJECTIVE: To observe the effects and clinical significance of C-reactive protein in patients with craniocerebral injury after hyperbaric oxygenation. DESIGN: Randomized controlled study. SETTING: Departments of Neurosurgery, Laboratory and Hyperbaric Oxygen, the Second Affiliated Hospital, Medical College of Shantou University. PARTICIPANTS: A total of 60 patients with craniocerebral injury were selected from Department of Neurosurgery, the Second Affiliated Hospital, Medical College of Shantou University from October 2006 to April 2007. There were 37 males and 23 females and the mean age was 26 years. All subjects were certainly diagnosed as history of craniocerebral injury. Patients hospitalized at 24 hours after injury, Glasgow Coma Score ranged from 3 to 12 points, and all patients were certainly diagnosed with CT or MR scanning. Patients and their relatives provided confirmed consent. All the subjects were randomly divided into hyperbaric oxygenation group and control group with 30 in each group. METHODS: Patients in the control group were treated with routinely neurosurgical therapy after hospitalization; however, based the same basic treatment in the control group, patients in the hyperbaric oxygenation group received hyperbaric oxygenation by using iced-wheel four-door 2-cabin air-compression chamber (made in Yantai) from 24 hours to 10 days after operation or injury. After entering the cabin, patients who had a clear consciousness breathed the oxygen by using face mask; contrarily, patients directly breathed the oxygen. Therapeutic project: Expression was increased for about 15–20 minutes, maintained for about 70–80 minutes, and decreased for 20 minutes. Otherwise, pressure was maintained from 0.2 to 0.25 MPa. Hyperbaric oxygenation took an hour for once a day and 10 times were regarded as a course. Venous blood was collected before treatment and on the next day of the first course end. Content of C-reactive protein in plasma was measured with immune turbidimetry in hyperbaric oxygenation group; in addition, content of C-reactive protein in plasma was directly measured with the same method at the corresponding time in the control group. If the content was less or equal to 8 mg/L, it was regarded as normal value. Effects of the two groups were evaluated based on Glasgow Coma Score before and after treatment. MAIN OUTCOME MEASURES: Content of plasma C-reactive protein and Glasgow Coma Score in the two groups before and after treatment. RESULTS: All 60 patients were involved in the final analysis. ① Content of plasma C-reactive protein: The two contents were obviously higher than normal value after craniocerebral injury. There was no significant difference in the two groups before treatment (P > 0.05), but both contents were decreased after treatment, and there was significant difference between HBOT group and control group after treatment (t =4.756, P < 0.01). In addition, there was significant difference in hyperbaric oxygen therapy group before and after treatment (t =5.236, P < 0.01). ② Glasgow Coma Score: There was no significant difference in the two groups before treatment (P > 0.05), but scores were increased in both groups after treatment (t =9.92, 2.51, P < 0.01, 0.05); on the other hand, therefore, there was significant difference between the two groupsafter treatment (t =9.21, P < 0.01). CONCLUSION: Hyperbaric oxygenation can remarkably decrease content of plasma C-reactive protein in patients with craniocerebral injury at the phase of stress. | Zeyu Xie Minghua Zhuang Lan Lin Hongwu Xu Linxing Chen Lina Hu | 2007 | Neural Regeneration Research2007，2，5： | 9 |
| 5 | Sulfur-enriched alkaloids from the root of Isatis indigotica显示文摘Five new sulfur-enriched alkaloids isatithioetherins A–E(1–5), and two pairs of scalemic enantiomers(t)-and( à)-isatithiopyrin B(6 a and 6 b) and isoepigoitrin and isogoitrin(7 a and 7 b), along with the known scalemic enantiomers epigoitrin and goitrin(8 a and 8 b), were isolated and characterized from an aqueous extract of the Isatis indigotica roots. Their structures were determined by extensive spectroscopic data analysis, including 2 D NMR and theoretical calculations of electronic circular dichroism(ECD) spectra based on the quantum-mechanical time-dependent density functional theory(TDDFT). Compounds 1–5 represent a novel group of sulfur-enriched alkaloids, biogenetically originating from stereoselective assemblies of epigoitrin-derived units. Isolation and structure characterization of 6 a and 6 b support the postulated biosynthetic pathways for the diastereomers 9 a and 9 b via a rare thio-Diels–Alder reaction. Compounds 2 and 4 showed antiviral activity against the influenza virus A/Hanfang/359/95(H3 N2, IC500.60 and 1.92 μmol/L) and the herpes simplex virus 1(HSV-1, IC503.70 and 2.87 μmol/L), and 2 also inhibited Coxsackie virus B3(IC500.71 μmol/L).& 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/). | Qinglan Guo Chengbo Xu Minghua Chen Sheng Lin Yuhuan Li Chenggen Zhu JiANDong Jiang Yongchun Yang Jiangong Shi | 2018 | Acta Pharmaceutica Sinica B2018，8，6： | 8 |
| 6 | Formulation of a new ocean salinity boundary condition and impact on the simulated climate of an oceanic general circulation model显示文摘The salinity boundary condition at the ocean surface plays an important role in the stability of long-term integrations of an oceanic general circulation model(OGCM) and in determining its equilibrium solutions.This study presents a new formulation of the salt flux calculation at the ocean surface based on physical processes of salt exchange at the air-sea interface.The formulation improves the commonly used virtual salt flux with constant reference salinity by allowing for spatial correlations between surface freshwater flux and sea-surface salinity while preserving the conservation of global salinity.The new boundary condition is implemented in the latest version of the National Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics/Institute of Atmospheric Physics Climate Ocean Model version 2(LICOM2.0).The impact of the new boundary condition on the equilibrium simulations of the model is presented.It is shown that the new formulation leads to a stronger Atlantic meridional overturning circulation(AMOC) that is closer to observational estimates.It also slightly improves poleward heat transport by the oceans in both the Atlantic and the global oceans. | JIN JiangBo ZENG QingCun WU Lin LIU HaiLong ZHANG MingHua | 2017 | Science China Earth Sciences2017，60，3： | 7 |
| 7 | A critical epitope in CD147 facilitates memory CD4^(+) T-cell hyper-activation in rheumatoid arthritis显示文摘The abnormal activation of CD4^(+)CD45RO+memory T(Tm)cells plays an important role in the pathogenesis of rheumatoid arthritis(RA).Previous studies have shown that CD147 participates in T-cell activation.However,it remains unclear whether CD147 is involved in abnormal Tm-cell activation in RA patients.In this study,we demonstrated that CD147 was predominantly upregulated in Tm cells derived from RA patients.The anti-CD147 mAb 5A12 specifically inhibited Tm-cell activation and proliferation and further restrained osteoclastogenesis.Using a structural–functional approach,we depicted the interface between 5A12 and CD147.This allowed us to identify two critical residues,Lys63 and Asp65,as potential targets for RA treatment,as the double mutation K63A/D65A inhibited Tm-cell activation,mimicking the neutralization by 5A12.This study provides not only a theoretical basis for a“CD147-Tm/Osteoclast-RA chain”for the potential prevention and treatment of RA or other T-cell-mediated autoimmune diseases but also a new target for related drug design and development. | Na Guo Sheng Ye Kui Zhang Xiaoling Yu Hongyong Cui Xiangmin Yang Peng lin Minghua Lv Jinlin Miao Yang Zhang Qing Han Rongguang Zhang Zhinan Chen Ping Zhu | 2019 | Cellular & Molecular Immunology2019，16，6： | 6 |
| 8 | miR-137 and miR-491 Negatively Regulate Dopamine Transporter Expression and Function in Neural Cells显示文摘The dopamine transporter(DAT) is involved in the regulation of extracellular dopamine levels.A 40-bp variable-number tandem repeat(VNTR) polymorphism in the 3'-untranslated region(3'UTR) of the DAT has been reported to be associated with various phenotypes that are involved in the aberrant regulation of dopaminergic neurotransmission.In the present study,we found that miR-137 and miR-491 caused a marked reduction of DAT expression,thereby influencing neuronal dopamine transport.Moreover,the regulation of miR-137 and miR-491 on this transport disappeared after the DAT was silenced.The miR-491 seed region that is located on the VNTR sequence in the 3'UTR of the DAT and the regulatory effect of miR-491 on the DAT depended on the VNTR copy-number.These data indicate that miR-137 and miR-491 regulate DAT expression and dopamine transport at the posttranscriptional level,suggesting that microRNA may be targeted for the treatment of diseases associated with DAT dysfunction. | Xiaojian Jia Feng Wang Ying Han XuewenGeng Minghua Li Yu Shi Lin Lu Yun Chen | 2016 | Neuroscience Bulletin2016，32，6： | 5 |
| 9 | Deep placement of nitrogen fertilizer increases rice yield and nitrogen use efficiency with fewer greenhouse gas emissions in a mechanical direct-seeded cropping system显示文摘Deep placement of nitrogen fertilizer is a key strategy for improving nitrogen use efficiency. A two-year field experiment was conducted during the early rice growing seasons(March–July) of 2016 and 2017.The experimental treatments comprised two rice cultivars: Wufengyou 615(WFY 615) and Yuxiangyouzhan(YXYZ), and three N treatments: mechanical deep placement of all fertilizers as basal dose at 10 cm soil depth(one-time deep-placement fertilization, namely OTDP fertilization);manual surface broadcast(the common farmer practice) of 40% N fertilizer at one day before sowing(basal fertilizer)followed by broadcast application of 30% each at tillering and panicle initiation stages;and no fertilizer application at any growth stage as a control. One-time deep-placement fertilization increased grain yield of both rice cultivars by 11.8%–19.6%, total nitrogen accumulation by 10.3%–13.1%, nitrogen grain production efficiency by 29.7%–31.5%, nitrogen harvest index by 27.8%–30.0%, nitrogen agronomic efficiency by 71.3%–77.2%, and nitrogen recovery efficiency by 42.4%–56.7% for both rice cultivars, compared with the multiple-broadcast treatment. One-time deep-placement fertilization reduced CH4-induced global warming potential(GWP) by 20.7%–25.3%, N2O-induced GWP by 7.2%–12.3%, and total GWP by 14.7%–22.9% for both rice cultivars relative to the multiple-broadcast treatment. The activities of glutamine synthetase and nitrate reductase were increased at both panicle-initiation and heading stages in both rice cultivars following one-time deep-placement fertilization treatment. Larger leaf area index at heading stage and more favorable root morphological traits expressed as larger total root length, mean root diameter, and total root volume per hill were also observed. One-time deep-placement fertilization could be an effective strategy for increasing grain yield and nitrogen use efficiency and lowering greenhouse-gas emissions under mechanical direct-seeded cropping systems. | Lin Li Hua Tian Minghua Zhang Pingshan Fan Umair Ashraf Haidong Liu Xiongfei Chen Meiyang Duan Xiangru Tang Zaiman Wang Zheng Zhang Shenggang Pan | 2021 | The Crop Journal2021，9，6： | 4 |
| 10 | Selenium Enrichment in Cambrian Stratabound Gold Deposits in the Western Qinling Mountains显示文摘Stratabound gold deposits in the western Qinling Mountains occur in Cambrian chert formation composed of carbonaceous chert and carbonaceous slate. The distinctive chert formation provides important grounds for the mineralization and controls on the formation of gold deposits. Study shows that Se is exceptionally higher in both host rocks and gold orebodies. It may be recovered as a valuable component in ores for total utilization, and in some localities even independent Se orebodies (which are mined exclusively for Se) may be delineated. In gold ore Se mainly occurs as independent minerals or in the isomorphous form in sulphides and there is a positive correlation between Se and Au. | Liu Jiajun,Open Laboratory of Ore Deposit Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang, Guizhou 550002Zheng Minghua, Chengdu Institute of Technology, Chengdu, Sichuan 610059Liu Jianming, Research Centre of Mineral Resources Exploration, Chinese Academy of Sciences,Beijing 100101Zhou Yufeng, Gu Xuexiang, Zhang Bin, Lin Li, Chengdu Institute of Technology, Chengdu, Sichuan 610059and Lu Wenquan Institute of Comprehensive Utilization of Mineral Resources, Chengdu, Sichuan 610041 | 1997 | Acta Geologica Sinica(English Edition)1997，71，4： | 3 |
| 11 | 2017 Chinese expert consensus on the clinical application ofserum marker for thyroid cancer显示文摘In recent years, the clinical incidence of thyroid cancer has been increasing year by year, and its risk assessment and clinical management methods have also been accordingly modified and constantly improved. There are great differences between the clinical diagnostic and therapeutic modes and disease management of thyroid cancer employed by various medical institutions in China, particularly with regard to the clinical application of serum marker of thyroid cancer. To this end, the China Anti-Cancer Association Thyroid Cancer Specialized Committee Chinese Association of Thyroid Oncology organized this compilation of ExpertConsensus on Clinical Application of Serum Marker of Thyroid Cancer to help and impel relevant clinical institutions and professionals to standardize clinical diagnosis, treatment, and long-term management of thyroid cancer, and to properly utilize the serum marker for scientific auxiliary clinical diagnosis and assessment of thyroid cancer before and after operation. | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Wei Cui Li Gao Zairong Gao Lin Guo Zhuming Guo Tao Huang Xiaoming Huang Yansong Lin Qinjiang Liu Xin Ni Jianwu Qin Li Ren Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Bin Zhang DaiweiZhao Ying Zheng Jingqiang Zhu Xiangqian Zheng 无 | 2018 | Cancer Biology & Medicine2018，15，4： | 3 |
| 12 | Effects of different long-term crop straw management practices on ammonia volatilization from subtropical calcareous agricultural soil显示文摘长期秸秆还田或秸秆焚烧会显著影响土壤肥力及土壤氮素循环,但该措施对土壤氨挥发的影响仍尚不明确。本研究利用秸秆还田长期定位试验小区,研究了无秸秆配施(CK),配施100%或50%秸秆(SI1, SI2)和配施50%秸秆焚烧(SI2B)对土壤氨挥发的影响。结果表明:氨挥发在小麦季持续38天,而玉米季持续7–10天。秸秆还田显著影响混施基肥期的土壤氨挥发而非表施追肥期。与CK相比, SI1和SI2分别降低了35.1%和16.1%的年累积氨排放,可能因为秸秆的高C/N比及较高的微生物活性促进了无机氮的固定降低土壤NH4+的浓度。SI2B比SI2增加了29.9%的氨排放。因此,长期合理的秸秆还田可为石灰性旱地土壤氨挥发减排提供选择和依据。 | ZHANG Bowen ZHOU Minghua LIN Hongyu NTACYABUKURA Tite WANG Yanqiang ZHU Bo | 2020 | Atmospheric and Oceanic Science Letters2020，13，3： | 3 |
| 13 | Cellulose Functionalization via ATRP Grafting of Glycidyl Methacrylate for Cr(VI) Adsorption显示文摘纤维素在经由原子转移激进分子聚合(ATRP ) 的离子的液体是有 glycidyl methacrylate (GMA ) 的第一 grafted 然后介绍环氧基树脂组与 ethanediamine (EDA ) 被反应获得氨基的吸附物。grafting 共聚物和获得的吸附物被 FTIR, 1H NMR, TEM 和 SEM 描绘。结果证明 grafted 共聚物与控制得好的分子的重量和多分散性有 grafted 聚合物链,聚合是一个控制系统。纤维素吸附物在表面上有众多的 micropores 并且为 Cr (VI ) 吸附显示出高效。吸附行为是依赖的 pH,吸着平衡在吸附物上在 2 h 以内被完成。 | Chunxiang Lin Sha Qiao Danhui Liu Minghua Liu | 2013 | Chinese Journal of Chemistry2013，31，12： | 3 |
| 14 | Proteomic analysis of a toxic dinoflagellate Alexandrium catenella under different growth phases and conditions显示文摘Alexandrium is a widely spread dinoflagellate genus throughout many regions of the world,which not only causes the harmful algal blooms(HABs) but also results in the paralytic shellfish poisoning(PSP) throughout the world.This study compared protein profiles of A.catenella grown under different growth phases and conditions using a proteomic approach,and identified the differentially expressed proteins.The results showed that the expressions of proteins identified in three different regions of the gels,the groups 1,2 and 3 proteins,varied significantly with the growth phases and conditions.Group 1 proteins and six Group 2 proteins were highly expressed at the initial,exponential and stationary growth phases,eight Group 2 proteins were highly expressed only at the initial phase,and Group 3 proteins were highly expressed at the exponential and/or stationary phases.However,all these proteins were expressed at low levels or were barely visible at the dissipation phase.The expressions of groups 1 and 2 proteins were low or barely visible in various growth conditions except in continuous darkness they were highly expressed.Group 3 proteins,on the other hand,were overexpressed in continuous illumination and expressed at low levels or barely visible in continuous darkness or under nitrate-starvation.The data from MALDI-TOF-TOF mass spectrometry demonstrated that these differentially expressed proteins were associated with macromolecular biosynthesis,photosynthesis,tRNA synthesis and DNA stability,stress response and cell division regulation.Synthetase was the major component of the altered proteins.This is one of the first comprehensive proteomic study of a dinoflagellate,A.catenella,that provides a fundamental understanding of the proteins involved in A.catenella growth and response to environmental stresses,and potential physiological indicator proteins related to growth and environmental stress have been identified. | WANG DaZhi LIN Lin WANG MingHua LI Cheng HONG HuaSheng | 2012 | Chinese Science Bulletin2012，57，25： | 2 |
| 15 | Bio-remediation of acephate–Pb(Ⅱ) compound contaminants by Bacillus subtilis FZUL-33显示文摘Removal of Pb^(2+)and biodegradation of organophosphorus have been both widely investigated respectively. However, bio-remediation of both Pb^(2+)and organophosphorus still remains largely unexplored. Bacillus subtilis FZUL-33, which was isolated from the sediment of a lake, possesses the capability for both biomineralization of Pb^(2+)and biodegradation of acephate. In the present study, both Pb^(2+)and acephate were simultaneously removed via biodegradation and biomineralization in aqueous solutions.Batch experiments were conducted to study the influence of p H, interaction time and Pb^(2+)concentration on the process of removal of Pb2+. At the temperature of 25°C, the maximum removal of Pb^(2+)by B. subtilis FZUL-33 was 381.31 ± 11.46 mg/g under the conditions of p H 5.5, initial Pb^(2+)concentration of 1300 mg/L, and contact time of 10 min. Batch experiments were conducted to study the influence of acephate on removal of Pb^(2+)and the influence of Pb2+on biodegradation of acephate by B. subtilis FZUL-33. In the mixed system of acephate–Pb2+, the results show that biodegradation of acephate by B. subtilis FZUL-33 released PO43+, which promotes mineralization of Pb2+. The process of biodegradation of acephate was affected slightly when the concentration of Pb2+was below 100 mg/L. Based on the results, it can be inferred that the B. subtilis FZUL-33 plays a significant role in bio-remediation of organophosphorus-heavy metal compound contamination. | Wenting Lin Zhen Huang Xuezhen Li Minghua Liu Yangjian Cheng | 2016 | Journal of Environmental Sciences2016，28，7： | 2 |
| 16 | Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis显示文摘 | Xiaobing Chen Yongsheng Wang Hongping Xia Qiwu Wang Xiaochun Jiang Zihong Lin Yuedong Ma Yang Yang Minghua Hu | 2012 | Molecular Biology Reports2012，，： | 2 |
| 17 | Anovel multi-dimensional features fusion algorithm for the EEG signal recognition of brain’s sensorimotor region activated tasks显示文摘Purpose-Aiming at the shortcomings of EEG signals generated by brain’s sensorimotor region activated tasks,such as poor performance,low efficiency and weak robustness,this paper proposes an EEG signals classification method based on multi-dimensional fusion features.Design/methodology/approach-First,the improved Morlet wavelet is used to extract the spectrum feature maps from EEG signals.Then,the spatial-frequency features are extracted from the PSD maps by using the three-dimensional convolutional neural networks(3DCNNs)model.Finally,the spatial-frequency features are incorporated to the bidirectional gated recurrent units(Bi-GRUs)models to extract the spatial-frequencysequential multi-dimensional fusion features for recognition of brain’s sensorimotor region activated task.Findings-In the comparative experiments,the data sets of motor imagery(MI)/action observation(AO)/action execution(AE)tasks are selected to test the classification performance and robustness of the proposed algorithm.In addition,the impact of extracted features on the sensorimotor region and the impact on the classification processing are also analyzed by visualization during experiments.Originality/value-The experimental results show that the proposed algorithm extracts the corresponding brain activation features for different action related tasks,so as to achieve more stable classification performance in dealing with AO/MI/AE tasks,and has the best robustness on EEGsignals of different subjects. | Minghua Wei Feng Lin | 2020 | International Journal of Intelligent Computing and Cybernetics2020，13，2： | 1 |
| 18 | An optimization approach for solving signomial discrete programming prob-lems with free variables显示文摘 | Tsai Jungfa LIN Minghua | 2006 | Computers and Chemical Engineering2006，30，： | 1 |
| 19 | Highly efficient and selective removal of low-concentration antibiotics from aqueous solution by regenerable Mg(OH)2显示文摘The prevalent presence of fluoroquinolone antibiotics in aquatic environments has attracted considerable attention because of their harmful effects on humans and the ecological environment.Magnesium hydroxide nanocrystals were found to act as a simple and effective adsorbent to remove low-concentration ciprofloxacin(CIP)in aqueous solution.The as-prepared Mg(OH)2 nanocrystals exhibited excellent CIP adsorption performance and high selectivity toward CIP molecules compared with other antibiotics or aromatics,e.g.,norfloxacin(NOR)and eosin B(EB).The adsorbent showed pH-dependent adsorption,indicating that the adsorption process is probably dominated by an electrostatic interaction mechanism.In addition,structural analysis of the adsorbent indicated that coordination and hydrogen bonding between CIP and Mg(OH)2 nanocrystal might also be involved in the adsorption process.Moreover,the adsorbent could be easily recovered by pyrolysis and hydration without significant reduction of adsorption capacity.The superior adsorption behavior of Mg(OH)2 nanocrystal indicates that it may serve as a potential adsorbent material candidate for the selective removal of CIP from aquatic environments. | Yongjing Wang Jingjing Lin Yonghao Wang Zemeng Liu Jinlu Lian Minghua Liu | 2020 | Journal of Environmental Sciences2020，32，1： | 1 |
| 20 | A matrix trace inequality and its application 显示文摘 | Shigeru Furuichi LIN Minghua | 2010 | Linear Algebra and Its Applications2010，433，： | 1 |
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