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| 1 | Gestational diabetes from A to Z显示文摘Gestational diabetes mellitus(GDM) is defined as any degree of hyperglycaemia that is recognized for the first time during pregnancy. This definition includes cases of undiagnosed type 2 diabetes mellitus(T2 DM) identified early in pregnancy and true GDM which develops later. GDM constitutes a greater impact on diabetes epidemic as it carries a major risk of developing T2 DM to the mother and foetus later in life. In addition, GDM has also been linked with cardiometabolic risk factors such as lipid abnormalities, hypertensive disorders and hyperinsulinemia. These might result in later development of cardiovascular disease and metabolic syndrome. The understanding of the different risk factors, the pathophysiological mechanisms and the genetic factors of GDM, will help us to identify the women at risk, to develop effective preventive measures and to provide adequate management of the disease. Clinical trials have shown that T2 DM can be prevented in women with prior GDM, by intensive lifestyle modification and by using pioglitazone and metformin. However, a matter of controversy surrounding both screening and management of GDM continues to emerge, despite several recent welldesigned clinical trials tackling these issues. The aim of this manuscript is to critically review GDM in a detailed and comprehensive manner, in order to provide a scientific analysis and updated write-up of different related aspects. | AbdelHameed Mirghani Dirar John Doupis | 2017 | World Journal of Diabetes2017，8，12： | 10 |
| 2 | Hypothyroidism during pregnancy: Controversy over screening and intervention显示文摘Thyroid hormones are critical for foetal neurological development and maternal health. Maternal hypothyroidism during pregnancy is associated with adverse impact on health of the mother as well as the progeny. Reduced thyroid hormone levels predispose the child to develop mental retardation and cognitive delay in early life. In the mother, hypothyroidism during pregnancy is associated with spontaneous abortion, placental abruption, preterm delivery and hypertensive disorders. Therefore, screening and therapeutic intervention is justified to prevent foetal as well as maternal co-morbidities. In view of impact of such a large-scale screening and intervention program on limited healthcare resources, it is debatable if a targeted rather than universal screening program will result in comparable outcomes. In addition, there is an ongoing debate regarding best evidence-based practice for the management of isolated hypothyroxinaemia, subclinical hypothyroidism and euthyroid women with autoimmune hypothyroidism. We have carried out a review of the literature; firstly, to determine whether universal screening for asymptomatic women in early pregnancy would be cost-effective. Secondly, we have retrospectively reviewed the literature to analyse the evidence regarding the impact of therapeutic intervention in women with subclinical hypothyroidism. | Abdel Hameed Mirghani Dirar Atul Kalhan | 2018 | World Journal of Obstetrics and Gynecology2018，7，1： | 2 |
| 3 | Analysis of potential lard adulteration in chocolate and chocolate products using fourier transform infrared spectroscopy 显示文摘 | Che Man Y B Syahariza Z A Mirghani M E S | 2005 | Food Chemistry2005，90，4： | 1 |
| 4 | Pregnancy oulcome post renal transplantation显示文摘 | Sgro MD Barozzino T Mirghani HM | 2002 | Teratology2002，65，： | 1 |
| 5 | Pregnancy outcome post renal transplantation显示文摘 | Sgro M D Barozzino T Mirghani H M | 2002 | Teratology2002，65，1： | 1 |
| 6 | The role of ultrasound in life-threatening situations in pregnancy 显示文摘 | Kadasne AR Mirghani HM | 2011 | J Emerg Trauma Shock2011，4，4： | 1 |
| 7 | The role of ultrasound in lifethreatening situations in pregnancy 显示文摘 | Kadasne AR Mirghani HM | 2011 | J Emery Trauma Shock2011，4，： | 1 |
| 8 | Early administration of enzyme replacement therapy for Pompe disease: short-term fol- low-up results显示文摘 | Hamdan MA Almalik MH Mirghani HM | 2008 | J Inherit Metab Dis2008，，： | 1 |
| 9 | Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers显示文摘 | Annika Allqvist Jun Miura Leif Bertilsson Rajaa A. Mirghani | 2007 | European Journal of Clinical Pharmacology2007，，2： | 1 |
| 10 | Pregnancy outcome post renal transplantation显示文摘 | Sgro MD Barozzino T Mirghani HM | 2002 | Teratology2002，65，1： | 1 |
| 11 | A new method for determining gossypol in cottonseed oil by FTIR spectroscopy 显示文摘 | Mirghani MES Man YBC | 2003 | Journal of the American Oil Chemists Society2003，80，7： | 1 |
| 12 | Gestational Dibetes Millitus:Fetal Liver Length Measurements Between 21 and 24 Weeks' Gestation 显示文摘 | Mirghani H Zayed R Thorns L | 2007 | Clin Ultrasound2007，35，1： | 1 |
| 13 | A New Method for Determining Gossypol in Cottonseed Oil by FTIR Spectroscopy 显示文摘 | Mirghani M E S Che Man Y B | 2003 | JAOCS2003，80，7： | 1 |
| 14 | Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro: 3-hydrox- ylation by CYP3A4 is indeed the major metabolic pathway显示文摘 | Mirghani RA Yasar U Zheng T | 2002 | Drug Metab Dispos2002，30，12： | 1 |
| 15 | Pregnancy outcome post renal transplantation显示文摘 | Barozzino T Mirghani HM | 2002 | Teratology2002，65，： | 1 |
| 16 | Reduction of high content of free fatty acid in sludge palm oil via acid catalyst for biodiesel production显示文摘 | Hayyan A Alam M Z Mirghani M E S | 2011 | Fuel Processing Technology2011，92，5： | 1 |
| 17 | Human papilloma virustesting in oropharyngeal squamous cell carcinoma:what theclinician should know?显示文摘 | Mirghani H Amen F Moreau F | 2014 | Oral Oncol2014，50，1： | 1 |
| 18 | The effect of maternal diet restriction on pregnancy outcome显示文摘 | Mirghani HM Hamud OA | 2006 | Am J Perinatol2006，23，： | 1 |
| 19 | Comparison between visual and computerized cardiotocography in low risk pregnancy 显示文摘 | Mirghani HM Khair H | 2005 | Saudi Med J2005，26，8： | 1 |
| 20 | Production of biodiesel from sludge palm oil by esterification process 显示文摘 | Hayyan A Alam M Z Mirghani M E S | 2009 | J Energy Power Eng2009，4，1： | 1 |
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