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| 1 | A study of pulmonary embolism after abdominal surgery in patients undergoing prophylaxis显示文摘AIM:To determine risk factors for pulmonary embolism and estimate effects and benefits of prophylaxis.METHODS:We included 78 patients who died subsequently to a pulmonary embolism after major abdomi nal surgery from 1985 to 2003.A first,retrospective analysis involved 41 patients who underwent elective surgery between 1985 and 1990 without receiving any prophylaxis.In the prospectively evaluated subgroup,37 patients undergoing major surgery between 1991 and 2003 were enrolled:all of them had received a prophylaxis consisting in low-molecular weight heparin,given subcutaneously at a dose of 2850 IU AXa/0.3 mL(body weight < 50 kg) or 5700 IU AXa/0.6 mL(body weight ≥ 50 kg).RESULTS:A higher incidence of thromboembolism(43.9% and 46.34% in the two groups,respectively) was found in older patients(> 60 years).The incidence of pulmonary embolism after major abdominal surgery in patients who had received the prophylaxis was signifi cantly lower compared to the subjects with the same condition who had not received any prophylaxis(P < 0.001,OR = 2.825;95% CI,1.811-4.408).Furthermore,the incidence of pulmonary embolism after colorectal cancer surgery was signifi cantly higher compared to incidence of pulmonary embolism after other abdominal surgical procedures.Finally,the incidence of pulmonary embolism after colorectal cancer surgery among the patients who had received the prophylaxis(11/4316,0.26%) was significantly lower compared to subjects undergoing a surgical procedure for the same indication but without prophylaxis(10/1562,0.64%)(P < 0.05,OR = 2.522;95% CI,1.069-5.949).CONCLUSION:Prophylaxis with low molecular weight heparin is highly recommended during the preoperative period in patients with diagnosis of colorectal cancer due to high risk of pulmonary embolism after elective surgery. | Mirko D Kerkez Dorde M ulafi Dragana D Mija Vitomir I Rankovi Nebja S Leki Dejan Z Stefanovi | 2009 | World Journal of Gastroenterology2009，15，3： | 14 |
| 2 | Color Doppler sonography and angioscintigraphy in hepatic Hodgkin's lymphoma显示文摘AIM:To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography (HRA) in secondary Hodgkin's hepatic lymphoma.METHODS:The research included patients with a diagnosis of Hodgkin's lymphoma with metastatic focal lesions in the liver and controls.Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal,hepatic and splenic veins were examined.Hepatic perfusion index (HPI) estimated by HRA was calculated.RESULTS:In the majority of patients,hepatomegaly was observed.Lesions were mostly hypoechoic and mixed,solitary or multiple.Some of the patients presented with dilated splenic veins and hepatofugal blood flow.A pulse wave was registered in the centre and at the margins of lymphoma.The average velocity of the pulse wave was higher at the margins (P>0.05).A continuous venous wave was found only at the margins of lymphoma.There was no linear correlation between lymphoma size and velocity of pulse and continuous wave (r=390,P<0.01).HPI was significantly lower in patients with lymphomas than in controls (P<0.05),pointing out increased arterial perfusion in comparison to portal perfusion.CONCLUSION:Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin's hepatic lymphoma and estimation of its intensity.Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions. | Mirjana V Stojkovi Vera M Artiko Irena B Radoman Slavko J Knezevi Snezana M Luki Mirko D Kerkez Nebojsa S Leki Andrija A Anti Marinko M Zuvela Vitomir I Rankovi Milorad N Petrovi Dragana P obi Vladimir B Obradovi | 2009 | World Journal of Gastroenterology2009，15，26： | 2 |
| 3 | Results of National Colorectal Cancer Screening Program in Croatia(2007-2011)显示文摘AIM:To study the epidemiologic indicators of uptake and characteristic colonoscopic findings in the Croatian National Colorectal Cancer Screening Program.METHODS:Colorectal cancer(CRC) was the second leading cause of cancer mortality in men(n = 1063,49.77/100 000),as well as women(n = 803,34.89/100 000) in Croatia in 2009.The Croatian National CRC Screening Program was established by the Ministry of Health and Social Welfare,and its implementation started in September,2007.The coordinators were recruited in each county institute of public health with an obligation to provide fecal occult blood testing(FOBT) to the participants,followed by colonoscopy in all positive cases.The FOBT was performed by hypersensitive guaiac-based Hemognost card test(Biognost,Zagreb).The test and short questionnaire were delivered to the home addresses of all citizens aged 50-74 years consecutively during a 3-year period.Each participant was required to complete the questionnaire and send it together with the stool specimen on three test cards back to the institute for further analysis.About 4% FOBT positive cases are expected in normal risk populations.A descriptive analysis was performed.RESULTS:A total of 1 056 694 individuals(born between 1933-1945 and 1952-1957) were invited to screening by the end of September 2011.In total,210 239(19.9%) persons returned the envelope with a completed questionnaire,and 181 102 of them returned it with a correctly placed stool specimen on FOBT cards.Until now,12 477(6.9%),FOBT-positive patients have been found,which is at the upper limit of the expected values in European Guidelines for Quality Assurance in CRC Screening and Diagnosis [European Union(EU) Guidelines].Colonoscopy was performed in 8541 cases(uptake 66%).Screening has identified CRC in 472 patients(5.5% of colonoscopied,3.8% of FOBT-positive,and 0.26% of all screened individuals).This is also in the expected range according to EU Guidelines.Polyps were found and removed in 3329(39% of colonoscopied) patients.The largest number of polyps were found in the left half of the colon:64%(19%,37% and 8% in the rectum,sigma,and descendens,respectively).The other 36% were detected in the proximal part(17% in the transverse colon and 19% in ceco-ascending colon).Small polyps in the rectum(5-10 mm in diameter),sigmoid and descending colon were histologically found to be tubular adenomas in 60% of cases,with a low degree of dysplasia,and 40% were classified as hyperplastic.Polyps of this size in the transverse or ceco-ascending colon in almost 20% had a histologically villous component,but still had a low degree of dysplasia.Polyps sized 10-20 mm in diameter were in 43% cases tubulovillous,and among them,32% had areas with a high degree of dysplasia,especially those polyps in the cecoascending or transverse part.The characteristics of the Croatian CRC Screening National Program in the first 3 years were as follows:relatively low percentage of returned FOBT,higher number of FOBT-positive persons but still in the range for population-based programs,and higher number of pathologic findings(polyps and cancers).CONCLUSION:These results suggest a need for intervention strategies that include organizational changes and educational activities to improve awareness of CRC screening usefulness and increase participation rates. | Miroslava Katii Nataa Antoljak Milan Kujundzi Valerija Stameni Dunja Skoko Poljak Danica Kramari Davor timac Marija Strnad Peikan Mirko amija Zdravko Ebling | 2012 | World Journal of Gastroenterology2012，18，32： | 2 |
| 4 | Endoscopic manometry of the sphincter of Oddi and pancreatic duct in patients with chronic pancreatitis显示文摘 | Milenko Uglje?i? Mirko Bulaji? Tomica Milosavljevi? Bojan ?timec | 1996 | International Journal of Pancreatology1996，，3： | 1 |
| 5 | The rate matching effect: A hidden property of a periodic stochastic resonance显示文摘 | MIRKO L MASSIMILIANO I Leone F | 2008 | Physics Letters A2008，372，15： | 1 |
| 6 | Generation of remote homogeneous magnetic fields显示文摘 | Mirko I | 2002 | IEEE Trans on Magnetics2002，38，3： | 1 |
| 7 | On the role of working fluid propertiesin Organic Rankine Cycle performance显示文摘 | Mirko Z Stijepovic Patrick Linke Athanasios I Pa-padopoulos | 2012 | Applied Ther-mal Engineering2012，36，： | 1 |
| 8 | Study ofdynamic multi-dimensional temperature and concentration distributionin liquid-sprayed fluidized beds 显示文摘 | Stefan H Jan B Markus H Matthias I Mirko P Lothar M | 2003 | Chemical Engineering Science2003，23，58： | 1 |
| 9 | The rate matc- hing effect: a hidden property of a periodic stochastic resonance 显示文摘 | MIRKO L MASSIMILIANO I LEONE F | 2008 | Physics Letters A2008，372，15： | 1 |
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