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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial显示文摘 | Eric Lawitz Fred F Poordad Phillip S Pang Robert H Hyland Xiao Ding Hongmei Mo William T Symonds John G McHutchison Fernando E Membreno | 2013 | The Lancet2013，，： | 5 |
| 3 | Effect of the Woods-Saxon nuclear distribution on the chiral magnetic field in Relativ- istic Heavy-ion Collisions显示文摘 | Mo Y J Feng S Q Shi Y F | 2013 | Physical Review C2013，88，88： | 1 |
| 4 | Biological marker compounds as indicators of depositional history of the Maoming oil shale显示文摘 | Brassell S C Eglinton G Mo F J | 1986 | Organic Geochemistry1986，10，： | 1 |
| 5 | Geochemical investigation of Early Cretaceous igneous rocks along an east-west traverse throughout the central Lhasa Terrane, Tibet显示文摘 | Zhu D C Mo X X Niu Y L Zhao Z D Wang L Q Liu Y S Wu F Y | 2009 | Chem Geol2009，268，34： | 1 |
| 6 | Statistical analysis and online monitoring for handling multiphase batch processes with varying du- rations 显示文摘 | ZHAO C H MO S GAO F R | 2011 | Journal of Process Control2011，21，6： | 1 |
| 7 | Development of microwave assisted extraction for the simultaneous determination of isoflavonoids and sa- ponins in radix astragali by high performance liquid chromatography显示文摘 | SONG J Z MO S F YIP Y K ct al | 2007 | J Sep Sci2007，30，6： | 1 |
| 8 | Serum immunoreactivity of SMP30 and its tissues expression in hepatocellular carcinoma显示文摘 | Zhou S F Mo F R Bin Y H | 2011 | Clinical Biochemistry2011，44，4： | 1 |
| 9 | Nickel-catalyzed propylene dimerization in organochloroaluminate ionic liq uids: control of the isomerization reaction显示文摘 | SOUZA R F D LEAL B C MO D S | 2007 | J Mol Catal A: Chem2007，272，12： | 1 |
| 10 | Multi{unctional magnetic nanoparticles {or targeted delivery显示文摘 | Kumar A Jena P K Behera S Lockey R F Mohapatra S Mo hapatra S | | Nanomedicine0，6，： | 1 |
| 11 | Clinical characteristics of 10 patients with continuous spikes and waves during slow sleep syndrome显示文摘 | Herguner MO Incecik F Altunbasak S | 2008 | Pediatr Neurol2008，38，6： | 1 |
| 12 | Scaffold development using 3D printing with a starch-based polymer显示文摘 | Lam C X F Mo X M Teoh S H | 2002 | Materials Science and Engineering: C2002，20，12： | 1 |
| 13 | Study on instability of the point bolster sheet metal dieless forming显示文摘 | MAO F MO J H HUANG S H | 2006 | Journal of Materials Processing Technology2006，176，： | 1 |
| 14 | A study of circulat- ing interleukin 10 in prognostication of unresectable hepa- tocellular carcinoma显示文摘 | Chan S L Mo F K Wong C S | 2012 | Cancer2012，118，16： | 1 |
| 15 | Psoralenoside and isopsoralenoside, two new benzofuran glycosidesfrom Psoralea corylifolia 显示文摘 | Qiao C F Han Q B Mo S F | 2006 | Chem Pharm Bull2006，54，5： | 1 |
| 16 | Scaffold development using 3D printing with a starch-based polymer显示文摘 | LAM C X F MO X M TEOH S H | 2002 | Materials Science & Engineering C-Biomimetic and Supramolecular Systems2002，20，12： | 1 |
| 17 | Effects of experimental nitrogen additions on plant diversity in an old-growth tropical forest显示文摘 | LU X MO J GILLIAM F S | 2010 | Global Change Biology2010，16，10： | 1 |
| 18 | The holy grail of science policy:exploring and combining bibliometric tools in search of scientific excellence显示文摘 | THED N VANLEEUWEN MARTIN S VISSER HENK F MOED TON J NEDERHOF ANTHONY F J VANRAAN | 2003 | Scientometrics2003，，2： | 1 |
| 19 | Scaffold development using 3D printing with a starch-based polymer 显示文摘 | LAM C X F MO X M TEOH S H HUTMACHER D W | 2002 | Mater Sci Eng C2002，20，12： | 1 |
| 20 | Hypouricemic action of selected flavonoids in mice: structure-activity relationships 显示文摘 | MO S F ZHOU F LV Y Z | 2007 | Biol Pharm Bull2007，30，8： | 1 |
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