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| 1 | nterferon alpha (IFNα)-induced TRIM22 interrupts HCV 'eplication by ubiquitinating NS5A显示文摘 | Chen Yang Xinhao Zhao Dakang Sun Leilei Yang Chang Chong Yu Pan Xiumei Chi Yanhang Gao Moli Wang Xiaodong Shi Haibo Sun Juan Lv Yuanda Gao Jin Zhong Junqi Niu Bing Sun | 2016 | Cellular & Molecular Immunology2016，13，1： | 13 |
| 2 | Numerical solution of oscillatory flow of Maxwell fluid in a rectangular straight duct显示文摘A numerical analysis is presented for the oscillatory flow of Maxwell fluid in a rectangular straight duct subjected to a simple harmonic periodic pressure gradient.The numerical solutions are obtained by a finite difference scheme method.The stability of this finite difference scheme method is discussed.The distributions of the velocity and phase difference are given numerically and graphically.The effects of the Reynolds number,relaxation time,and aspect ratio of the cross section on the oscillatory flow are investigated.The results show that when the relaxation time of the Maxwell model and the Reynolds number increase,the resonance phenomena for the distributions of the velocity and phase difference enhance. | Xuyang SUN Shaowei WANG Moli ZHAO Qiangyong ZHANG | 2019 | Applied Mathematics and Mechanics(English Edition)2019，40，11： | 2 |
| 3 | Identification of genes regulated by Wnt/β - catenin pathway and involved in apoptosis via microarray analysis显示文摘 | Moli Huang Yihua Wang Daochun Sun | 2006 | BMC Cancer2006，6，： | 1 |
| 4 | Identification of genes regulated by Wnt/β-catenin patlway and involved in apoptosis via microarray analysis显示文摘 | Moli Huang Yihua Wang ectal | 2006 | BMC Cancer2006，6，： | 1 |
| 5 | A longitudinal diffusion tensor imaging study on Wallerian degeneration of corticospinal tract after motor pathway stroke显示文摘 | Chunshui Yu Chaozhe Zhu Yujin Zhang Hai Chen Wen Qin Moli Wang Kuncheng Li | 2009 | Neuroimage2009，，2： | 1 |
| 6 | Verify the Function of a Potential Growth-Regulating Gene in Marine Bivalve Using a Candidate Model Organism Mulinia lateralis显示文摘A better understanding of genetic bases of growth regulation is essential for bivalve breeding,which is helpful to improve the yield of the commercially important bivalves.While previous studies have identified some candidate genes accounting for variation in growth-related traits through genotype-phenotype association analyses,seldom of them have verified the functions of these putative,growth-related genes beyond the genomic level due to the difficulty of culturing commercial bivalves under laboratory conditions.Fortunately,dwarf surf clam Mulinia lateralis can serve as a model organism for studying marine bivalves given its short generation time,the feasibility of being grown under experimental conditions and the availability of genetic and biological information.Using dwarf surf clam as a model bivalve,we characterize E2F3,a gene that has been found to account for variation in growth in scallops by a previous genome-wide association study,and verify its function in growth regulation through RNA interference(RNAi)experiments.For the first time,E2F3 in dwarf surf clam,which is termed as MulE2F3,is characterized.The results reveal that dwarf surf clams with MulE2F3 knocked down exhibit a reduction in both shell size and soft-tissue weight,indicating the functions of MulE2F3 in positively regulating bivalve growth.More importantly,we demonstrate how dwarf surf clam can be used as a model organism to investigate gene functions in commercial bivalves,shedding light on genetic causes for variation in growth to enhance the efficiency of bivalve farming. | WANG Chen KONG Lingling LIAN Shanshan YANG Zujing MENG Deting LI Moli ZHANG Xiangchao BAO Zhenmin HU Xiaoli | 2023 | Journal of Ocean University of China2023，22，4： | 0 |
| 7 | Identification of Monitoring Organ in Bivalves for Early Warning of Paralytic Shellfish Toxins Accumulation显示文摘Bivalve farming plays a dominant role in mariculture in China.Paralytic shellfish toxins(PSTs)can be accumulated in bivalves and cause poisoning the consumers.A sensitive detection of PSTs can provide early warning to decrease poisoning events in bivalve consuming.PSTs are traditionally examined using the whole soft-tissues.However,PSTs accumulation varies dramatically in different tissues of bivalves.Some tough tissues/organs(such as mantle),which account for a large proportion of the total soft body,exhibit a lower accumulation of PSTs and make the toxin extraction time-and reagent-consuming,potentially decreasing the accuracy and sensitivity of PSTs monitoring in bivalves.To develop a sensitive and cost-effective approach for PSTs examination in massively farmed bivalves,we fed three commercially important bivalves,Yesso scallop Patinopecten yessoensis,Pacific oyster Crassostrea gigas,and blue mussel Mytilus edulis with PSTs-producing dinoflagellate Alexandrium catenella,and detected PSTs concentration in different tissues.For all three bivalve species,the digestive gland accumulated much more PSTs than other tissues,and the digestive gland’s toxicity was significantly correlated with the PSTs toxicity of the whole soft-tissues,with r^(2)=0.94,0.92,and 0.94 for Yesso scallop,Pacific oyster,and blue mussel,respectively.When the toxicity of the whole soft-tissues reached 80μgSTXeq(100g)^(−1),the regulatory limit for commercial shellfish,the digestive gland’s toxicity reached 571.48,498.90,and 859.20μgSTXeq(100g)^(−1) in Yesso scallop,Pacific oyster,and blue mussel,respectively.Our results indicate that digestive gland can be used for the sensitive and cost-effective monitoring of PSTs in bivalves. | MENG Deting SHI Jiaoxia LI Moli WEI Zhongcheng WANG Yangrui XU Yiqiang LI Yubo BAO Zhenmin HU Xiaoli | 2023 | Journal of Ocean University of China2023，22，1： | 0 |
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