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| 1 | Portal vein thrombosis in liver cirrhosis显示文摘Portal vein thrombosis(PVT) is considered to be a frequent complication of liver cirrhosis. However, unlike PVT in patients without cirrhosis, very few data are available on the natural history and management of PVT in cirrhosis, despite its association with potentially life-threatening conditions, such as gastroesophageal bleeding and acute intestinal ischemia. Moreover, no consensus regarding PVT in cirrhosis exists. Suggested causes of PVT in cirrhosis include reduced portal blood flow velocity, multiple congenital or acquired thrombophilic factors, inherited or acquired conditions, and derangement of liver architecture. However, the understanding of PVT in cirrhosis is incomplete. In addition, information on the management of PVT in cirrhosis is inadequate. The aims of this review are to:(1) assemble data on the physiopathological mechanism, clinical findings, diagnosis and management of PVT in cirrhosis;(2) describe the principal factors most frequently involved in PVT development; and(3) summarize the recent knowledge concerning diagnostic and therapeutic procedures. | Nao Kinjo Hirofumi Kawanaka Tomohiko Akahoshi Yoshi-hiro Matsumoto Masahiro Kamori Yoshihiro Nagao Naotaka Hashimoto Hideo Uehara Morimasa Tomikawa Ken Shirabe Yoshihiko Maehara | 2014 | World Journal of Hepatology2014，6，2： | 38 |
| 2 | Impact of Antithrombin III Concentrates on Portal Vein Thrombosis After Splenectomy in Patients With Liver Cirrhosis and Hypersplenism显示文摘 | Hirofumi Kawanaka Tomohiko Akahoshi Nao Kinjo Kozou Konishi Daisuke Yoshida Go Anegawa Shohei Yamaguchi Hideo Uehara Naotaka Hashimoto Norifumi Tsutsumi Morimasa Tomikawa Yoshihiko Maehara | 2010 | Annals of Surgery2010，，1： | 2 |
| 3 | Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism显示文摘 | Akahoshi Tomohiko Tomikawa Morimasa Korenaga Daisuke | 2010 | Surgical Endoscopy2010，24，24： | 1 |
| 4 | Pathogenesis of portal hypertensive gastropathy: A clinical and experimental review显示文摘 | Masayuki Ohta Shohei Yamaguchi Norikazu Gotoh Morimasa Tomikawa | 2002 | Surgery2002，，1： | 1 |
| 5 | Antacid talcid activates in gastric mucosa genes encoding for EGF and its receptor. The molecular basis for its ulcer healing action显示文摘 | Andrzej S Tarnawski Morimasa Tomikawa Masayuki Ohta I.James Sarfeh | 2000 | Journal of Physiology - Paris2000，，2： | 1 |
| 6 | An assessment of surgery for portal hypertensive patients performed at a single community hospital显示文摘 | Morimasa Tomikawa Tomohiko Akahoshi Keishi Sugimachi Yasuharu Ikeda Daisuke Korenaga Kenji Takenaka Makoto Hashizume Yoshihiko Maehara | 2010 | Surgery Today2010，，7： | 1 |
| 7 | Despite activation of EGF-receptor-ERK signaling path way, epithelial proliferation is impaired in portal hypertensive gastric mucosa Relevance of MKP-1, c-fos, c-myc and cyclin D1 expression 显示文摘 | Hirofumi Kawanaka Morimasa Tomikawa Dolgor Baatar | 2001 | Life Sci2001，69，： | 1 |
| 8 | Antacid talcid activates in gastric mucosa genes encoding for EGF and its receptor. The molecular basis for its ulcer healing action显示文摘 | Andrzej S Tarnawski Morimasa Tomikawa Masayuki Ohta I.James Sarfeh | 2000 | Journal of Physiology - Paris2000，，： | 1 |
| 9 | Technical standardization of laparoscopic splenectomy harmonized with hand-assisted laparoscopic surgery for patients with liver cirrhosis and hypersplenism显示文摘 | Hirofumi Kawanaka Tomohiko Akahoshi Nao Kinjo Kozou Konishi Daisuke Yoshida Go Anegawa Shohei Yamaguchi Hideo Uehara Naotaka Hashimoto Norifumi Tsutsumi Morimasa Tomikawa Kenichi Koushi Noboru Harada Yasuharu Ikeda Daisuke Korenaga Kenji Takenaka Yoshihik | 2009 | Journal of Hepato - Biliary - Pancreatic Surgery2009，，6： | 1 |
| 10 | Quality of life after laparoscopy-assisted pylorus-preserving gastrectomy: an evaluation using a questionnaire mailed to the patients显示文摘 | Morimasa Tomikawa Daisuke Korenaga Tomohiko Akahoshi Kenichi Kohshi Keishi Sugimachi Yoshihiro Nagao Norifumi Tsutsumi Kenji Takenaka Yoshihiro Kakeji Makoto Hashizume Yoshihiko Maehara | 2012 | Surgery Today2012，，7： | 1 |
| 11 | A Comparison of an Open and Laparoscopic Appendectomy for Patients With Liver Cirrhosis显示文摘 | Kouji Tsugawa Nobuhiro Koyanagi Makoto Hashizume Morimasa Tomikawa Katsuhiko Ayukawa Kazuya Akahoshi Keizo Sugimachi | 2001 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2001，，3： | 1 |
| 12 | Predictive factors for platelet count after laparoscopic splenectomy in cirrhotic patients显示文摘 | Daisuke Yoshida Yoshihiro Nagao Morimasa Tomikawa Hirofumi Kawanaka Tomohiko Akahoshi Nao Kinjo Hideo Uehara Naotaka Hashimoto Makoto Hashizume Yoshihiko Maehara | 2012 | Hepatology International2012，，3： | 1 |
| 13 | Impact of Antithrombin III Concentrates on Portal Vein Thrombosis After Splenectomy in Patients With Liver Cirrhosis and Hypersplenism显示文摘 | Hirofumi Kawanaka Tomohiko Akahoshi Nao Kinjo Kozou Konishi Daisuke Yoshida Go Anegawa Shohei Yamaguchi Hideo Uehara Naotaka Hashimoto Norifumi Tsutsumi Morimasa Tomikawa Yoshihiko Maehara | 2010 | Annals of Surgery2010，，1： | 1 |
| 14 | Impact of balloon‐occluded retrograde transvenous obliteration on management of isolated fundal gastric variceal bleeding显示文摘 | Tomohiko Akahoshi Morimasa Tomikawa Masao Kamori Norifumi Tsutsumi Yoshihiro Nagao Makoto Hashizume Yoshihiko Maehara | 2012 | Hepatology Research2012，，： | 1 |
| 15 | Despite activation of EGF-receptor-ERK signaling pathway,epithelial proliferation is impairedin portal hypertensive gastric mucosa Relevance of MKP-1,c-fos,c-myc and cyclin D1 expression显示文摘 | Hirofumi Kawanaka Morimasa Tomikawa Dolgor Baatar | 2001 | Life Sciences2001，69，2001： | 1 |
| 16 | Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism显示文摘 | Tomohiko Akahoshi Morimasa Tomikawa Daisuke Korenaga Koji Ikejiri Motonori Saku Kenji Takenaka | 2010 | Surgical Endoscopy2010，，3： | 1 |
| 17 | The Feasibility and Effectiveness of a Hand-assisted Laparoscopic Splenectomy for Hypersplenism in Patients After Living-donor Liver Transplantation显示文摘 | Hideo Uehara Hirofumi Kawanaka Tomohiko Akahoshi Morimasa Tomikawa Nao Kinjo Naotaka Hashimoto Toru Ikegami Yuuji Soejima Akinobu Taketomi Yoshihiko Maehara | 2009 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2009，，6： | 1 |
| 18 | Technical standardization of laparoscopic splenectomy harmonized with hand-assisted laparoscopic surgery for patients with liver cirrhosis and hypersplenism显示文摘 | Hirofumi Kawanaka Tomohiko Akahoshi Nao Kinjo Kozou Konishi Daisuke Yoshida Go Anegawa Shohei Yamaguchi Hideo Uehara Naotaka Hashimoto Norifumi Tsutsumi Morimasa Tomikawa Kenichi Koushi Noboru Harada Yasuharu Ikeda Daisuke Korenaga Kenji Takenaka Yoshihik | 2009 | Journal of Hepato - Biliary - Pancreatic Surgery2009，，6： | 1 |
| 19 | Comparison of open, laparoscopic, and hand‐assisted laparoscopic devascularization of the upper stomach and splenectomy for treatment of esophageal and gastric varices: A single‐center experience显示文摘 | Tomohiko Akahoshi Hideo Uehara Morimasa Tomikawa Hirofumi Kawanaka Makoto Hashizume Yoshihiko Maehara | 2014 | Asian J Endosc Surg2014，，2： | 1 |
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