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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Biofabrication of natural hydrogels for cardiac,neural,and bone Tissue engineering Applications显示文摘Natural hydrogels are one of the most promising biomaterials for tissue engineering applications,due to their biocompatibility,biodegradability,and extracellular matrix mimicking ability.To surpass the limitations of conventional fabrication techniques and to recapitulate the complex architecture of native tissue structure,natural hydrogels are being constructed using novel biofabrication strategies,such as textile techniques and three-dimensional bioprinting.These innovative techniques play an enormous role in the development of advanced scaffolds for various tissue engineering applications.The progress,advantages,and shortcomings of the emerging biofabrication techniques are highlighted in this review.Additionally,the novel applications of biofabricated natural hydrogels in cardiac,neural,and bone tissue engineering are discussed as well. | Kamil Elkhoury Margaretha Morsink Laura Sanchez-Gonzalez Cyril Kahn Ali Tamayol Elmira Arab-Tehrany | 2021 | Bioactive Materials2021，6，11： | 2 |
| 3 | Monoclonal origin of primary unilateral multifocal pleomorphic adenoma of the parotid gland显示文摘 | Sylvia L. van Egmond Wendy W.J. de Leng Folkert H.M. Morsink G.Johan A. Offerhaus Lodewijk A.A. Brosens | 2012 | Human Pathology2012，，： | 1 |
| 4 | Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines显示文摘 | R. Sitarz R.J. Leguit W.W.J. de Leng F.H.M. Morsink W.P. Polkowski R. Maciejewski G.J.A. Offerhaus A.N. Milne | 2009 | Cellular Oncology2009，，6： | 1 |
| 5 | IL-1B ?31T>C promoter polymorphism is associated with gastric stump cancer but not with early onset or conventional gastric cancers显示文摘 | R. Sitarz W. W. J. Leng M. Polak F. H. M. Morsink O. Bakker W. P. Polkowski R. Maciejewski G. J. A. Offerhaus A. N. Milne | 2008 | Virchows Archiv2008，，3： | 1 |
| 6 | SGLT2 inhibitors for diabetes:turning symptoms into therapy 显示文摘 | Diamant M Morsink L M | 2013 | Lancet2013，382，9896： | 1 |
| 7 | Detection of colon flora in peritoneal drain fluid after colorectal surgery:canRT-PCR play a role in diagnosing anastomotic leakage?显示文摘 | Komen N Morsink MC Beiboer S | 2009 | J Microbiol Methods2009，79，1： | 1 |
| 8 | Correlations in the quasi-periodic oscillation frequencies of low-mass X-ray binaries and the relativistic precession model显示文摘 | Stella L Vietri M Morsink S M | | 0，，： | 1 |
| 9 | Squamous cell carcinoma in Barrett’s esophagus: field effect versus metastasis显示文摘 | M. M. Streppel P. D. Siersema W. W. de Leng F. H. Morsink F. P. Vleggaar A. Maitra E. A. Montgomery G. J. Offerhaus | 2012 | Diseases of the Esophagus2012，，7： | 1 |
| 10 | Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers 显示文摘 | Milne A N Carvalho R Morsink F M | 2006 | Mod Pathol2006，19，4： | 1 |
| 11 | Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines显示文摘 | R. Sitarz R.J. Leguit W.W.J. de Leng F.H.M. Morsink W.P. Polkowski R. Maciejewski G.J.A. Offerhaus A.N. Milne | 2009 | Cellular Oncology2009，，6： | 1 |
| 12 | Detection of colon flora in peritoneal drain fluid afteredoreetal surgery:can RT-PCR play a role in diagnosing anastomotic leakage?显示文摘 | Komen N Morsink MC Beiboer S | 2009 | J Microbiol Methods2009，79，1： | 1 |
| 13 | Associations between sex steroid hormone levels and depressive symptoms in elderly men and women:results from the health ABC study显示文摘 | Morsink LFJ Vogelzangs N Nicklas BJ | 2007 | Psychoneuroendocrinology2007，32，： | 1 |
| 14 | Multiple colorectal neoplasms in X-linked agammaglobulinemia 显示文摘 | Brosens LA Tytgat KM Morsink FH | 2008 | Clin Gastroen- terol Hepatol2008，6，1： | 1 |
| 15 | IL-1B ?31T>C promoter polymorphism is associated with gastric stump cancer but not with early onset or conventional gastric cancers显示文摘 | R. Sitarz W. W. J. Leng M. Polak F. H. M. Morsink O. Bakker W. P. Polkowski R. Maciejewski G. J. A. Offerhaus A. N. Milne | 2008 | Virchows Archiv2008，，3： | 1 |
| 16 | The gut- renalaxis: do incretin- based agents confer renoprotection indiabetes?显示文摘 | Muskiet MH Smits MM Morsink LM | 2014 | Nat Rev Nephrol2014，10，2： | 1 |
| 17 | Epithelial-Specific Loss of PTEN Results in Colorectal Juvenile Polyp Formation and Invasive Cancer显示文摘 | Victoria Marsh Durban Marnix Jansen Emma J. Davies Folkert H. Morsink G. Johan A. Offerhaus Alan R. Clarke | 2014 | The American Journal of Pathology2014，，1： | 1 |
| 18 | Associations between sex steroid hormone levels and depressive symptoms in elderly men and women:Results from the Health ABC study显示文摘 | Morsink L F J Vogelzangs N Nicklas B J | 2007 | Psychoneuroendocrinology2007，32，810： | 1 |
| 19 | SGLT2 inhibitors for diabetes: turning symptoms into therapy显示文摘 | Michaela Diamant Linde M Morsink | 2013 | The Lancet2013，，： | 1 |
| 20 | Expression of CD44 splice variants in human primary brain tumors显示文摘 | Kaaijk P Troost D Morsink F | 1995 | J Neurooncol1995，26，3： | 1 |
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