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6篇 您的检索式：作者名="Moyec"

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		题名	作者	年代	出处	被引量
	1	Nuclear magnetic resonance based metabolomics and liverdiseases:Recent advances and future clinical applications显示文摘Metabolomics is defined as the quantitative measurement of the dynamic multiparametric metabolic response of living systems to pathophysiological stimuli or genetic modification.It is an'omics'technique that is situated downstream of genomics,transcriptomics and proteomics.Metabolomics is recognized as a promising technique in the field of systems biology for the evaluation of global metabolic changes.During the last decade,metabolomics approaches have become widely used in the study of liver diseases for the detection of early biomarkers and altered metabolic pathways.It is a powerful technique to improve our pathophysiological knowledge of various liver diseases.It can be a useful tool to help clinicians in the diagnostic process especially to distinguish malignant and non-malignant liver disease as well as to determine the etiology or severity of the liver disease.It can also assess therapeutic response or predict drug induced liver injury.Nevertheless,the usefulness of metabolomics is often not understood by clinicians,especially the concept of metabolomics profiling or fingerprinting.In the present work,after a concise description of the different techniques and processes used in metabolomics,we will review the main research on this subject by focusing specifically on in vitro proton nuclear magnetic resonance spectroscopy based metabolomics approaches in human studies.We will first consider the clinical point of view enlighten physicians on this new approach and emphasis its future use in clinical'routine'.	Roland Amathieu Mohamed Nawfal Triba Corentine Goossens Nadia Bouchemal Pierre Nahon Philippe Savarin Laurence Le Moyec	2016	World Journal of Gastroenterology2016，22，1：	6
	2	TRIMETAZIDINE PREVENTS RENAL INJURY IN THE ISOLATED PERFUSED PIG KIDNEY EXPOSED TO PROLONGED COLD ISCHEMIA显示文摘	Thierry Hauet Denis Mothes Jean-Michel Goujon Jean Claude Caritez Michel Carretier Laurence le Moyec Michel Eugene Jean-Paul Tillement	1997	Transplantation1997，，7：	1
	3	Decrease of P-glycoprotein activity in K562/ ADR cells by MβCD and filipin and lack of effect in- duced by cholesterol oxidase indicate that this trans- porter is not located in rafts显示文摘	Reungpatthanaphong P Marbeuf-Gueye C Le Moyec L	2004	J Bioenerg Biomem- br2004，36，6：	1
	4	Call and membrance lipid analysis by proton magnetic resonance spectroscopy in five breast cancer cell lines显示文摘	Le Moyec L Tatoud M Eugene M	1992	Br J Cancer1992，66，4：	1
	5	NMR metabolomics for assessment of exercise effects with mouse biofluids 显示文摘	LE MOYEC L MILLE-HAMARD L TRIBA M N	2012	Anal Bioanal Chem2012，404，2：	1
	6	NMR metabolomics for assessment of exercise effects with mouse biofluids 显示文摘	LE MOYEC L MILLE-HAMARD L TRIBA MN	2012	Anal Bioanal Chem2012，404，2：	1

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