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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | Synthesis of zeolites from thermally activated kaolinite some observations on nucleation and growth 显示文摘 | Murat M Amokrane A Baastide J P Montanaro L | 1992 | Clay Minerals1992，27，： | 1 |
| 3 | In-Situ Determi- nation of Creep Properties of Sea Ice with the Pres- suremeter显示文摘 | Murat J R Ladanyi B Huneauit P | 1989 | Canadian Geotechnical Journal1989，26，： | 1 |
| 4 | Perioperative f~Sti0g i~ ~dults aqd children:guidelines from the European Society of Anaesthesiology 显示文摘 | Smith I Kranke P Murat I | 2011 | Eur J Anaesthesio12011，28，8： | 1 |
| 5 | Synthesis of Zeolites from thermally activated kaolinite,some observations on nucleation and growth显示文摘 | Murat M Amokrane A Bastide J P Montanaro L | 1992 | Clay Minerals1992，27，： | 1 |
| 6 | Perioperative fasting in adults and chil- dren:Guidelines from the European Society of Anaesthesiology 显示文摘 | Smith I Kranke P Murat I | 2011 | Euro J Anaesthesiol2011，28，8： | 1 |
| 7 | Locally recurrent prostate can- cer after initial radiation therapy: early salvage high-intensity focused ultrasound improves oncologic outcomes显示文摘 | Crouzet S Murat F J Pommier P | 2012 | Radiother Oncol2012，105，2： | 1 |
| 8 | The draft genome of watermelon (Citrullus lanatus ) and reseqnencing of 20 diverse accessions显示文摘 | Guo S G Zhang J G Sun H H Salse J Lucas W J Zhang H Y Zheng Y Mao L Y Ren Y WangZ W Min J M Guo X S Murat F Ham B K Zhang Z L Gao S Huang M Xu Y M Zhong S L Bombarely A Mueller L Zhao H He H Q Zhang Y Zhang Z H Huang S W Tan T Pang E Lin K Hu Q Kuang H H Ni P X Wang B Liu J G Kou Q H Hou W J Zou X H Jiang J Gong G Y Klee K Schoof H Huang Y Hu X S Dong S S Liang D Q Wang J Wu K Xia Y Zhao X Zheng Z Q Xing M Liang X M Huang B Q Lv T Wang J Y Yin Y Yi H P Li R Q Wu M Z Levi A Zhang X P Giovannoni J Wang J Li YF Fei Z J Xu Y | 2013 | Nature genetics2013，45，1： | 1 |
| 9 | miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells 显示文摘 | Sun GQ Ye P Murat K | 2011 | Nature communications2011，2，： | 1 |
| 10 | Diagnosis, management, and results of treatment for aortopulmo- narywindow显示文摘 | MURAT M TUFAN P ATIF A | 2004 | Cardiol Young2004，14，： | 1 |
| 11 | Mass spec- trometry identification of potential mediators of progestin - only contraceptive - induced abnormal uterine bleeding in human endo- metrial stromal cells 显示文摘 | John P Shapiro Murat Basar Umit A Kayisli | 2015 | Contraception2015，91，3： | 1 |
| 12 | Perioperative fasting in adults and children: guidelines from the European Society of Anaesthe- siology显示文摘 | Smith I Kranke P Murat I | 2011 | Eur J Anaesthesiol2011，28，8： | 1 |
| 13 | Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins显示文摘 | Wu L Murat P Matak-Vinkovic D | 2013 | Biochemistry2013，52，52： | 1 |
| 14 | Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins显示文摘 | Wu L Murat P Matak-Vinkovic D | 2013 | Biochemistry2013，52，52： | 1 |
| 15 | Perioperafive fasting in adults and children:guidelines from the European Society of Anaesthei- ology 显示文摘 | Smith I Kranke P Murat I | 2011 | Eur J Anaesthesio12011，28，8： | 1 |
| 16 | Perioperative fasting in adults and children:guidelines from the European Society of Anaesthesiology显示文摘 | Smith I Kranke P Murat I | 2011 | Eur J Anaesthesiol2011，28，8： | 1 |
| 17 | The comparison of socio-eco-nomic conditions and personal hygiene habits of neuro-Beh§et,s dis-ease and multiple sclerosis patients显示文摘 | Munevver P Murat K Erdem T | 2011 | Int J Hyg Environ Health2011，214，4： | 1 |
| 18 | Adrenal Lymphangioma Mimicking Renal Cyst: A Case Report and Review of the Literature显示文摘 | Murat Akand Mustafa Kucur P?nar Karabagli Ozcan Kilic Bedreddin Seckin Serdar Goktas L. Ammar-Keskes M. Gallucci C. Liao | 2013 | Case Reports in Urology2013，，： | 1 |
| 19 | Thymic neuroendocrine tumors in multiple endocrine neoplasia type 1 : a comparative study on 21 cases among a series of 761 MEN 1 from the GTE ( Groupe des Tumeurs Endoerines) 显示文摘 | Goudet P Murat A Cardot-Bauters C | 2009 | World J Surg2009，33，6： | 1 |
| 20 | Polymorphism at the ribosomal DNA ITS and its relation to postglacial re-colonization routes of the Perigord truffle Tuber melanosporum显示文摘 | Murat C Diez J Luis P | 2004 | New Phytologist2004，164，2： | 1 |
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