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| 1 | Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions. | Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro | 2019 | World Journal of Clinical Oncology2019，10，10： | 5 |
| 2 | Addition of statins to the standard treatment in patients with cirrhosis:Safety and efficacy显示文摘This review summarizes the safety and efficacy of statins in patients with cirrhosis.Due to concerns about the safety of statins in patients with impaired liver function,they have recently been investigated as a potential treatment option in cirrhosis.The most clinically significant adverse event is statin-related myopathy,and this may be related to the high serum statin concentrations in the setting of severely impaired liver function.Rhabdomyolysis is the most serious and potentially life-threatening manifestation.It has recently been demonstrated that the recommended dose of simvastatin in patients with decompensated cirrhosis would be 20 mg/d because higher values,such as 40 mg/d,are associated with many adverse events,especially muscle injury.Likewise,simvastatin should not be administered to patients with Model for End-stage Liver Disease score>12 and/or Child-Pugh class C because of the high risk of severe muscle injury.Due to the pleiotropic effects,the focus on statins has shifted from being considered harmful to something useful.Through these effects,statins could prevent liver-related morbidity and mortality in cirrhotic patients.Observational studies in large populations of patients with cirrhosis have shown that treatment with statins to decrease high cholesterol levels was associated with a reduced risk of hepatic decompensation,hepatocellular carcinoma development and death.The few randomized controlled trials in patients with cirrhosis and portal hypertension showed that statins lower portal pressure,quite likely through a reduction in hepatic resistance.Another large randomized controlled trial in patients with variceal bleeding showed that simvastatin in addition to standard of care did not prevent rebleeding but improved survival rate.Despite these encouraging outcomes,the quality of the evidence regarding the use of statins is low or very low due to the observational characteristics of most of the studies involved.Therefore,it is advisable to perform further randomized controlled trials on a large series of patients with hard clinical endpoints,using different statin types and varying doses.The objectives would be to prevent liver-related morbidity and mortality rather than treating cirrhosis complications to take additional information that makes it possible to add statins to the standard of care of these patients. | Alberto E Muñoz Florencia D Pollarsky Mónica Marino Mariano Cartier Horacio Vázquez Pablo Salgado Gustavo Romero | 2021 | World Journal of Gastroenterology2021，27，28： | 4 |
| 3 | Analysis of concrete from corroded sewer pipe显示文摘 | DAVIS J L NICA D | 1998 | International Biodeterioration and Biodegradation1998，42，2： | 1 |
| 4 | Quantifying microbially induced deterioration of concrete:initial studies显示文摘 | D J Roberts D Nica G Zuo | 2002 | International Biodeterioration & Biodegradation2002，49，： | 1 |
| 5 | Absence of alphavbe- ta6 integrin is linked to initiation and progression of perio- dontaldisease显示文摘 | Ghannad F1 Nica D Fulle MI | 2008 | Am J Pathol2008，172，5： | 1 |
| 6 | Growth cruves for Pinus elliottii,Pinus taeda and Pinus radiata in two areas of the Calamuchita Valley显示文摘 | MóNICA D EDUARDO A GRACIELA V | 1997 | For Ecol Manage1997，95，： | 1 |
| 7 | Biological Signatures of Asymptomatic Extra- and Intracranial Atherosclerosis: The Barcelona-AsIA (Asymptomatic Intracranial Atherosclerosis) Study显示文摘 | Elena López-Cancio Amparo Galán Laura Dorado Marta Jiménez María Hernández Mónica Millán Silvia Reverté Anna Su?ol Jaume Barallat Anna Massuet Maria Teresa Alzamora Antonio Dávalos Juan Francisco Arenillas | 2012 | Stroke2012，，10： | 1 |
| 8 | Quantilying microbially induced deterioration of concrete:initial studies显示文摘 | ROBERTS D J NICA D ZUO G et a1 | 2002 | InterBiodeter Biodegr2002，49，： | 1 |
| 9 | Consumer preferences for wine applying best-worst scaling: a Spanish case study显示文摘 | Rodolfo Bernabéu Mónica Díaz Raquel Olivas Miguel Olmeda | 2012 | British Food Journal2012，，9： | 1 |
| 10 | Bioaccumulative and conehologieal assessment of heavy metal transfer in a soil - plant - snail foodchain显示文摘 | NICA D V BURA M GERGEN I | 2012 | Chem Cent J2012，6，1： | 1 |
| 11 | Free Random Variables,CMR Monograph Series显示文摘 | Voiculescu D Dykema K Nica A | 1992 | Amer Math Soc1992，1，： | 1 |
| 12 | The African swine fever virus dynein-binding protein p54 induces infected cell apoptosis显示文摘 | Bruno Hernáez Gema D??az-Gil Mónica Garc??a-Gallo José Ignacio Quetglas Ignacio Rodr??guez-Crespo Linda Dixon José M Escribano Covadonga Alonso | 2004 | FEBS Letters2004，，1： | 1 |
| 13 | Modulation of the Activities of Catalase, Cu-Zn, Mn Superoxide Dismutase, and Glutathione Peroxidase in Adipocyte from Ovariectomised Female Rats with Metabolic Syndrome显示文摘 | Rebeca Cambray Guerra Alejandra Zu?iga-Mu?oz Verónica Guarner Lans Eulises Díaz-Díaz Carlos Alberto Tena Betancourt Israel Pérez-Torres Joseph R. Vasselli | 2014 | International Journal of Endocrinology2014，，： | 1 |
| 14 | Photomicrographic evaluation of the apical sealing capacity of three types of gutta - percha master cones : an in vitro study 显示文摘 | Nica LM Didilescu A Rusu D | 2012 | Odontology2012，100，1： | 1 |
| 15 | 法国立体定向脑电图指南显示文摘立体定向脑电图(SEEG)在上世纪60年代诞生于法国,由J.Talairach和J.Bancaud共同发明。SEEG为一种介入方法,可用于耐药性局灶癫痫,对癫痫放电在三维空间内进行实时记录,为'解剖-电关联分析'及精确外科切除提供客观依据。尽管这种方法被部分欧洲癫痫中心专家沿用长达数十年,然而,仅在近十年来才在世界范围内逐渐推广应用。在当代医疗实践中,SEEG不仅为诊断方法,也被用于治疗,如射频热凝治疗等。为达到临床上更加合理应用SEEG的目的,我们认为需要有正式指南,为此成立了特别工作组,由全法国各地大型癫痫中心(过去连续5年中每年完成SEEG超过10例)专家组成。先由工作组会议形成初步建议,然后由全体专家依据已有方法学对其进行评分。指南第一部分包括下列主题内形成框架建议:SEEG适应证与局限性;SEEG计划与实施;外科技术;电生理操作技术;SEEG解读;SEEG引导下射频热凝。指南的第二部分,由各个专家小组基于现有文献以及他们个人经验对这些议题的具体内容进一步详述。这项工作旨在向应用SEEG的癫痫中心提供了解法国专家共识的机会,尤其是那些正处在起步阶段的癫痫中心,可以作为参考蓝本。该指南的编写得到法国临床神经生理学会、国际抗癫痫联盟法国分支机构的支持。 | Isnard J Taussig D Bartolomei F Bourdillon P Catenoix H Chassoux F Chipaux M Clémenceau S Colnat-Coulbois S Denuelle M Derrey S Devaux B Dorfmüller G Gilard V Guenot M Job-Chapron AS LandréE Lebas A Maillard L McGonigal A Minotti L Montavont A Navarro V Nica A Reyns N Scholly J Sol JC Szurhaj W Trebuchon A Tyvaert L Valenti-Hirsch MP Valton L Vignal JP Sauleau P 龙绮婷 张翠荣 尚力 张玮 刘兴洲 | 2018 | 癫痫杂志2018，4，4： | 1 |
| 16 | Serum Cellular Fibronectin and Matrix Metalloproteinase-9 as Screening Biomarkers for the Prediction of Parenchymal Hematoma After Thrombolytic Therapy in Acute Ischemic Stroke: A Multicenter Confirmatory Study显示文摘 | Mar Castellanos Tomás Sobrino Mónica Millán María García Juan Arenillas Florentino Nombela David Brea Natalia Perez de la Ossa Joaquín Serena José Vivancos José Castillo Antoni Dávalos | 2007 | Stroke2007，，6： | 1 |
| 17 | Photomicrographic evaluation of the apical sealing capacity of three types of gutta-percha master cones:an in vitro study显示文摘 | Nica LM Didilescu A Rusu D | 2012 | Odontology2012，100，1： | 1 |
| 18 | Substituent effects on the reaction mode between 2-hydroxybenzyl alcohol derivatives and MEM chloride: synthesis and mechanistic aspects of seven- and ten-membered benzo-fused O , O -acetals显示文摘 | Estrella Saniger Mónica Díaz-Gavilán Beatriz Delgado Duane Choquesillo Josefa M. González-Pérez Stefania Aiello Miguel á. Gallo Antonio Espinosa Joaquín M. Campos | 2004 | Tetrahedron2004，，50： | 1 |
| 19 | Demographic data,natural history,and prognostic factors of idiopathic thrombocytopenic purpura in children:a multicentered study from argentina显示文摘 | Hugo D Armando P Mnica M | 2009 | Pediatr Blood Cancer2009，52，： | 1 |
| 20 | Tonometry as a predictor of inadequate splanchnic perfusion in an intra-abdominal hypertension animal model显示文摘 | Laura Correa-Martín Gregorio Castellanos Mónica García-Lindo Idoia Díaz-Güemes Francisco M. Sánchez-Margallo | 2013 | Journal of Surgical Research2013，，： | 1 |
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