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19篇 您的检索式:作者名="Nagy MA"
    题名 作者 年代 出处 被引量
1Inhibition of angiogenesis and HCT-116 xenograft tumor growth in mice by kallistatin显示文摘AIM: To investigate the inhibitory effect of kallistatin (KAL) on angiogenesis and HCT-116 xenograft tumor growth. METHODS: Heterotopic tumors were induced by subcutaneous injection of 2 × 106 HCT-11 cells in mice. Seven days later, 2 × 1011 rAAV-GFP or rAAV-KAL was injected intratumorally (n = 5 for each group). The mice were sacrificed at d 28, by which time the tumors in the rAAV-GFP group had grown to beyond 5% of the total body weight. Tumor growth was measured by calipers in two dimensions. Tumor angiogenesis was determined with tumor microvessel density (MVD) by immunohistology. Tumor cell proliferation was assessed by Ki-67 staining. RESULTS: Intratumor injection of rAAV-KAL inhibited tumor growth in the treatment group by 78% (171 ± 52 mm3) at d 21 after virus infection compared to the control group (776 ± 241 mm3). Microvessel density was significantly inhibited in tumor tissues treated with rAAV-KAL. rAAV-KAL also decreased the proportion of proliferating cells (Ki-67 positive cells) in tumors compared with the control group.CONCLUSION: rAAV-mediated expression of KAL inhibits the growth of colon cancer by reducing angiogenesis and proliferation of tumor cells, and may provide a promising anti-angiogenesis-based approach to the treatment of metastatic colorectal cancer.Yong Diao Jian Ma Wei-Dong Xiao Jia Luo Xin-Yan Li Kin-Wah Chu Peter WC Fung Nagy Habib Farzin Farzaneh Rui-An Xu 2007World Journal of Gastroenterology2007,13,34:15
2Systemic inflammation enhances surgery-induced cognitive dysfunction in mice显示文摘António Rei Fidalgo Mario Cibelli John P.M. White Istvan Nagy Mervyn Maze Daqing Ma 2011Neuroscience Letters2011,,:1
3Spontaneous histologic lesions of the adult naked mole rat (Heterocephalus glaber): A retrospective survey of lesions in a zoo population 显示文摘Delaney MA Nagy L Kinsel MJ 2013Vet Pathol2013,50,4:1
4Variabilitv of standsrd clinical protein assays in the analysis of a model urine solution of fragmented albumin显示文摘Eppel GA Nagy S Jenkins MA 2000Clin Biochem2000,33,:1
5Nomega-nitro-L-arginine methylester ameliorates myocardial toxicity induced by doxorubicin显示文摘Mansour MA El-Din AG Nagi MN 2003J Biochem Mol Biol2003,6,6:1
6Protective effect of aminoguanidine against nephrotoxicity induced by cisplatin in normal rats 显示文摘Mansour MA Mostafa AM Nagi MN 2002Comp Biochem Physiol CToxicol Pharmacol2002,132,:1
7Protective effect of aminoguanidine against nephrotoxicity induced by cisplatin in normal rats显示文摘Mansour MA Mostafa AM Nagi MN 2002Comp Biochem Physiol C Toxicol Pharmacol2002,132,:1
8Aluminous cements containing magnesium aluminate spinel from Egyptian dolomite显示文摘Khalil Nagy MA EI-Henaly SAS Girgis Lamey G 2001Ceramics International2001,,27:1
9Variability of standard clinical protein assays in the analysis of a model urine solution of fragmented albumin 显示文摘Eppel GA Nagy S Jenkins MA 2000Clin Bioehem2000,33,6:1
10Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats:a possible mechanism of proteetion显示文摘Nagi MN Mansour MA 2000Phamlaeol Res2000,41,3:1
11Protective effect of amin- oguanidine against nephrotoxieity induced by cisplatin in normal rats显示文摘Mansour MA Mostafa AM Nagi MN 2002Comp Biochem Physiol C Toxicol Pharmacol2002,132,2:1
12Innate immunity and cell death in alcoholic liver disease: role of cytochrome P4502El显示文摘Barnes MA Roychowdhury S Nagy LE 2014Redox Biol2014,8,2:1
13Cytokeratin-19 fragments, nueleosomes and neuron-specific enolase as early measures of ehemotherapy response in non-small eell lung eaneer显示文摘Alm El-Din MA Farouk G Nagy H 2012Int J Biol Markers2012,27,2:1
14Systemic inflammation enhances surgery-induced cognitive dysfunction in mice显示文摘António Rei Fidalgo Mario Cibelli John P.M. White Istvan Nagy Mervyn Maze Daqing Ma 2011Neuroscience Letters2011,,1:1
15Protective effect of aminoguanidine against nephrotoxicity induced by cisplatin in normal rats 显示文摘Mansour MA Mostafa AM Nagi MN 2002Comp Biochem Physiol CToxicol Pharmacol2002,132,:1
16Experimental acute pancreatitis results in increased blood-brain barrier permeability in the rat:a potential role for tumor necrosis factor and interleukin 6显示文摘Farkas G Marton J Nagy Z Mandi Y Takacs T Deli MA 1998Neurosci Lett1998,242,:1
17Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats:A possible mechanism of protection 显示文摘 Mansour MA 2000Pharmacol Res2000,41,3:1
18Aluminous cements containing magnesium aluminate spinel from Egyptian dolomite显示文摘Nagy MA El - Hemaly S A S Lamey G G 2001Ceram Inter2001,27,8:1
19Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats显示文摘Amin KA Nagy MA 2009Diabetol Metab Syn- dr2009,1,1:1
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