|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pharmacological interventions for improved colonic anastomotic healing:A meta-analysis显示文摘AIM:To identify pharmaceuticals for the prophylaxis of anastomotic leakage(AL),we systematically reviewed studies on anastomosis repair after colorectal surgery.METHODS:We searched PubMed and EMBASE for articles published between January 1975 and December 2012.We included studies in English with the primary purpose of promoting healing of anastomoses made in the colon or rectum under uncomplicated conditions.We excluded studies on adverse events from interventions,nutritional interventions or in situ physical supporting biomaterials.The primary outcome was biomechanical strength or AL.We performed meta-analyses on therapeutic agents investigated by three or more independent research groups using the same outcome.The DerSimonian-Laird method for random effects was applied with P < 0.05.RESULTS:Of the 56 different therapeutic agents assessed,7 met our inclusion criteria for the metaanalysis.The prostacyclin analog iloprost increased the weighted mean of the early bursting pressure of colonic anastomoses in male rats by 60 mmHg(95%CI:30-89) vs the controls,and the immunosuppressant tacrolimus increased this value by 29 mmHg(95%CI:4-53) vs the controls.Erythropoietin showed an enhancement of bursting pressure by 45 mmHg(95%CI:14-76).The anabolic compound growth hormone augmented the anastomotic strength by 21 mmHg(95%CI:7-35),possibly via the up-regulation of insulin-like growth factor-1,as this growth factor increased the bursting pressure by 61 mmHg(95%CI:43-79) via increased collagen deposition.Hyperbaric oxygen therapy increased the bursting pressure by 24 mmHg(95%CI:13-34).Broad-spectrum matrix metalloproteinase inhibitors increased the bursting pressure by 48 mmHg(95%CI:31-66) on postoperative days 3-4.In the only human study,the AL incidence was not significantly reduced in the 103 colorectal patients treated with aprotinin(11.7%) compared with the 113 placebo-treated patients(9.7%).CONCLUSION:This systematic review identified only one randomized clinical trial and seven therapeutic agents from pre-clinical models that could be explored further for the prophylaxis of AL after colorectal surgery. | Mari Nanna φines Peter-Martin Krarup Lars Nannestad Jorgensen Magnus Sven Agren | 2014 | World Journal of Gastroenterology2014，20，35： | 5 |
| 2 | 年龄>75岁成人他汀类药物的使用情况及不良反应显示文摘自2013年美国心脏病学会/美国心脏协会指南发布以来,目前常规社区治疗实践中老年人用他汀类药物情况不很清楚。研究者比较了在不考虑指南推荐的年龄标准的情况下,符合接受一级或二级预防他汀类药物使用标准年龄〉75和≤75岁成年人的他汀类药物使用和剂量状况。 | 刘青 叶鹏 Nanna MG Navar AM Wang TY Mi X Virani SS Louie MJ Lee LV Goldberg AC Roger VL Robinson J Peterson ED | 2018 | 中华高血压杂志2018，26，7： | 4 |
| 3 | 神经病理性疼痛:用于研究和临床实践的分级系统更新显示文摘一、介绍
1994年国际疼痛学会(International Association for the Study Pain, IASP)定义神经病理性疼痛为"神经系统原发性损伤或功能障碍所引起或导致的疼痛".2008年,IASP神经病理性疼痛特别兴趣小组(NeuPSIG)把定义修改为"由躯体感觉系统的损伤或疾病而直接导致的疼痛",后由IASP分类委员会稍作修改为"由躯体感觉系统的损伤或疾病而导致的疼痛". | Nanna B Finnerup 浦少锋 | 2017 | 中国疼痛医学杂志2017，23，11： | 3 |
| 4 | A critical review on natural compounds interacting with the plant plasma membrane H^(+)-ATPase and their potential as biologicals in agriculture显示文摘The plant plasma membrane(PM)H^(+)-ATPase is an essential enzyme controlling plant growth and development.It is an important factor in response to abiotic and biotic stresses and is subject to tight regulation.We are in demand for new sustainable natural growth regulators and as a key enzyme for regulation of transport into the plant cell the PM H^(+)-ATPase is a potential target for these.In this review,we have evaluated the known non-protein natural compounds with regulatory effects on the PM H^(+)-ATPase,focusing on their mechanism of action and their potential as biologicals/growth regulators in plant production of future sustainable agriculture. | Nanna W.Havshφi Anja T.Fuglsang | 2022 | Journal of Integrative Plant Biology2022，64，2： | 2 |
| 5 | A fluid dynamics study in a 50 cc pulsatile ventricular assist device: influence of heart rate variability显示文摘 | Nanna JC Navitsky MA Topper SR | 2011 | J Biomech Eng2011，133，10： | 1 |
| 6 | Calcium homeostasis and bone metabolis m during pregnancy, lactation, and postweaning :a longitudinal study显示文摘 | Laura SH | 1995 | Am J Clin1995，61，： | 1 |
| 7 | Adenosine A1receptors me-diate local anti-nociceptive effects of acupuncture显示文摘 | Nanna Goldman1 4 Michael Chen | 2010 | Nature Neuroscience2010，13，： | 1 |
| 8 | Assessing the pattern of ST-segment depression during subendocardial ischemia using a computer simulation of the ventricular electrogram显示文摘 | Mauro Bertella Michele Nanna Emilio Vanoli Filippo Scalise | 2009 | Journal of Electrocardiology2009，，： | 1 |
| 9 | Intravenous lidocaine relieves spinal cord injury pain:a randomized controlled trial显示文摘 | Nanna B Finnerup Fin Biering-S(o)rensen Inger L Johannesen | | 0，，05： | 1 |
| 10 | Ethanol production in immobilized-cell bioreactors from mixed sugar syrups and enzymatic hydrolysates of steam-exploded biomass 显示文摘 | De Bari I Cuna D Nanna F | 2004 | Appl Biochem Biotechnol2004，，： | 1 |
| 11 | Pump blood pro- cessing, salvage and re-transfusion improves hemoglobin levels after coronary artery bypass grafting, but affects co- agulative and fibrinolytic systems显示文摘 | Scrascia G Rotunno C Nanna D | 2012 | Perfusion2012，27，4： | 1 |
| 12 | Assessing the pattern of ST-segment depression during subendocardial is chemia using a computer simula- tion of the ventsicular electrogram 显示文摘 | Bertella M Nanna M Vanoli E | 2009 | J Electrocardiol2009，42，1： | 1 |
| 13 | Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of cor-neodesmosomes显示文摘 | Jean-Pierre H Truus R Nanna S | 2010 | J Invest Dermatol2010，130，3： | 1 |
| 14 | Acid impregnation and steam explosion of corn stover in batch processes显示文摘 | ZIMBARDI F VIOLA E NANNA F | 2007 | Ind Crop Prod2007，26，2： | 1 |
| 15 | Developing the library: Between efficiency, account ability an dorms of recognition 显示文摘 | Nanna K Andersen J | 2009 | Journal of Documentation2009，，2： | 1 |
| 16 | Programmed Cell Death 4 (PDCD4) Is an Important Functional Target of the MicroRNA miR-21 in Breast Cancer Cells显示文摘 | Lisa B Frankel Nanna D Christoffersen Anders Jacobsen | 2008 | The Journal of Biological Chemistry2008，283，2： | 1 |
| 17 | Influence of antibiotics on regeneration efficiency in tomato 显示文摘 | Mamidala P Nanna RS | 2009 | Plant Omics Journal2009，2，4： | 1 |
| 18 | Central post-stroke pain: clinical characteristics, pathophysiology, and management显示文摘 | Henriette Klit Nanna B Finnerup Troels S Jensen | 2009 | Lancet Neurology2009，，： | 1 |
| 19 | Effect of different haptencarrierconjugation ratios and molecular orientations on antibody affinityagainst a peptide antigen 显示文摘 | Maiken K Pedersen A Nanna S | 2006 | J Immunol Methods2006，311，12： | 1 |
| 20 | Mg-rich coating: a new paradigm for Cr-free corrosion protection of A1 aerospace alloys显示文摘 | NANNA M E BIERWAGEN G P | 2004 | JCT Research2004，1，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员