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21篇 您的检索式:作者名="Naosuke"
    题名 作者 年代 出处 被引量
1Endoplasmic reticulum stress transducer old astrocyte specifically induced substance contributes to astrogliosis after spinal cord injury显示文摘Old astrocyte specifically induced substance(OASIS) is an endoplasmic reticulum(ER) stress transducer specifically expressed in astrocytes and osteoblasts. OASIS regulates the differentiation of neural precursor cells into astrocytes in the central nervous system. This study aimed to elucidate the involvement of ER stress responses stimulated via OASIS in astrogliosis following spinal cord injury. In a mouse model of spinal cord contusion injury, OASIS m RNA and protein expression were evaluated at days 7 and 14. A significant increase in OASIS m RNA on day 7 and an increase in protein on days 7 and 14 was observed in injured spinal cords. Immunostaining on day 7 revealed co-localization of OASIS and astrocytes in the periphery of the injury site. Furthermore, anti-OASIS small interfering RNA(si RNA) was injected at the injury sites on day 5 to elucidate the function of OASIS. Treatment with anti-OASIS si RNA caused a significant decrease in OASIS m RNA on day 7 and protein on days 7 and 14, and was associated with the inhibition of astrogliosis and hindlimb motor function recovery. Results of our study show that OASIS expression synchronizes with astrogliosis and is functionally associated with astrogliosis after spinal cord injury.Atsushi Takazawa Naosuke Kamei Nobuo Adachi Mitsuo Ochi 2018Neural Regeneration Research2018,13,3:4
2Interleukin-I as a pathogenetic mediator of ischemic brain damage in rats显示文摘Yasando Y Naosuke M Hidetaka S 1995Stoke1995,26,4:1
3Isolation, sequence and bacterial expression of a eDNA for (S) - tetrahydroberberine oxidase from cultured berberine- producing Coptis japonica cells 显示文摘Naosuke O Koizumi N Tanaka T 1989Pro Nati Acad Sci USA1989,86,2:1
4Pharmacological Preconditioning Protects Lung Injury Induced by Intestinal Ischemia/Reperfusion in Rat显示文摘Koji Ito Hisashi Ozasa Naosuke Kojima Mitsutaka Miura Takehisa Iwai Haruki Senoo Saburo Horikawa 2003Shock2003,,5:1
5Interleukin-1as a pathogenetic mediator of ische-mic brain damage in rats显示文摘Yasundo Yamasaki Naosuke Matsuura Hidetaka Shozu-hara 1995Stroke1995,26,:1
6Intergeneric co-culture of genetically transformed organs for the production of scopolamine 显示文摘Okada Naosuke Verpoorte R 1998Phytochem USA1998,86,1:1
7Intergeneric co - culture of genetically transformed organs for the production of scopolamine 显示文摘Okada Naosuke Verpoorte R 1989Proc Natl Acad Sci USA1989,86,1:1
8Dry coating: an innovative enteric coating method using a cellulose derivative 显示文摘Obara Sakae Maruyama Naosuke Nishiyama Yuichi 1999Eur J Pharm Biopharm1999,47,1:1
9Isolation ofthree new sesquiterpene lactones from the periearps of Illieium majus显示文摘Isao Kouno Naosuke Baba Miwa Hashimoto Nobusuke Kawano Masakatsu Takahashi Hiroshi Kaneto Chun-shu Yang Sadao Sato 1989Chem Pharm Bull1989,37,9:1
10A new sesquiterpene lactone and its glucoside from the pericarps of Illicium majus 显示文摘Isao Kouno Naosuke Baba Miwa Hashimoto Nobusuke Kawano Chun-shu Yang Sadao Sato 1989Chem Pharm Bull1989,37,9:1
11A new toxic neoanisation derivative from the pericarps of Illicium majus显示文摘Chun-shu Yang Miwa Hashimoto Naosuke Baba Masakatsu Takahashi Hiroshi Kaneto Nobusuke Kawano Isao Kouno 1990Chem Pharm Bull1990,38,1:1
12Pharmacological preconditioning protects lung injury induced by intestine ischemial / reperfusion in rat 显示文摘Koji ho Hisashi Ozasa Naosuke 2003Shock2003,19,5:1
13TERT promoter mutations in primary and secondary glioblastomas显示文摘Naosuke Nonoguchi Takashi Ohta Ji-Eun Oh Young-Ho Kim Paul Kleihues Hiroko Ohgaki 2013Acta Neuropathologica2013,,6:1
14Postoperative Segmental C5 Palsy After Cervical Laminoplasty May Occur Without Intraoperative Nerve Injury: A Prospective Study With Transcranial Electric Motor-Evoked Potentials显示文摘Nobuhiro Tanaka Kazuyoshi Nakanishi Yasushi Fujiwara Naosuke Kamei Mitsuo Ochi 2006Spine2006,,26:1
15Bone marrow stromal cells that enhanced fibroblast growth factor-2 secretion by herpes simplex virus vector improve neurological outcome after transient focal cerebral ischemia in rats显示文摘Naokado Ikeda Naosuke Nonoguchi Ming Zhu Zhao 2005Stroke2005,36,12:1
16Effects of water stress on sorbitol production and anatomical changes in the nuclei of leaf and root cells of young loquat tress显示文摘Cui S M Chen G L Naosuke Nii 2003J Japan Soc Hort Sci2003,72,:1
17Effects of water stress on sorbitol production and anatomical changes in the nuclei of leaf and root cells of young loquat tress 显示文摘Cui Shimao Chen Guilin Nil Naosuke 2003Journal of the Japanese Society for Horticultural Science2003,72,5:1
18Anatomical Development of Phi Thickening and the Casparian Strip in Loquat Roots显示文摘Pan C X Yoshinori Nakao and Naosuke Nii 2006J Soc Hort Sci2006,,6:1
19Isolation ,sequence and bacterial expression of a cDNA for (s)-tetrahy-droberberine oxidase from cultured berberine- producing Coptis japonica cells显示文摘 Koizumi N Tanaka T 1989Proc Natl Acad Sci USA1989,86,:1
20Primary Xylem Differentiation Relative to Differences in Root Diameter in Various Fruit Tree Species显示文摘Pan C X Naosuke Nii 2005Journal of Meijo University2005,,41:1
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