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| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | The global image of the Moon obtained by the Chang'E-1:Data processing and lunar cartography显示文摘The global lunar image of the first phase of Chinese Lunar Exploration Program is the first image that covered all over the surface of the Moon. It will serve as a critical foundation for succeeding exploration and scientific research. In this paper, the acquisition, characteristics, and data quality of Chang'E-1 CCD image data are described in detail. Also described are the methodology and procedure of data processing. According to rule of planetary cartography, the image data have been processed, geometrically corrected, and then mosaicked and merged in a scale of 1:2.5 million. The results of data processing and charting show that the image data of Chang'E-1 CCD and their geometric precision meet the demand of charting a map in the scale of 1:2.5 million. The relative geometric positioning precision of the global image is better than 240 m, and the absolute geometric positioning precision is slightly better than that of the ULCN2005 and Clementine lunar basemap (V2.0). The plane positioning precision is approximately 100-1500 m. This global image proves to be the best global image of the Moon so far in terms of space coverage, image quality, and positioning precision. | LI ChunLai1, LIU JianJun1, REN Xin1, MOU LingLi1, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, ZHAO BaoChang2, YANG JianFeng2, ZOU XiaoDuan1, WANG Min1, XU Chun1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, LI JunDuo1 & OUYANG ZiYuan11 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China | 2010 | Science China Earth Sciences2010，53，8： | 22 |
| 3 | Laser altimetry data of Chang'E-1 and the global lunar DEM model显示文摘The Laser AltiMeter (LAM), as one of the main payloads of Chang'E-1 probe, is used to measure the topography of the lunar surface. It performed the first measurement at 02:22 on November 28th, 2007. Up to December 4th 2008, the total number of measurements was approximately 9.12 million, covering the whole surface of the Moon. Using the LAM data, we constructed a global lunar Digtal Elevation Model (DEM) with 3 km spatial resolution. The model shows pronounced morphological characteristics, legible and vivid details of the lunar surface. The plane positioning accuracy of the DEM is 445 m (1σ), and the vertical accuracy is 60 m (1σ). From this DEM model, we measured the full range of the altitude difference on the lunar sur-face, which is about 19.807 km. The highest point is 10.629 km high, on a peak between crater Korolev and crater Dirichlet-Jackson at (158.656°W, 5.441°N) and the lowest point is -9.178 km in height, inside crater Antoniadi (172.413°W, 70.368°S) in the South Pole-Aitken Basin. By comparison, the DEM model of Chang'E-1 is better than the USA ULCN2005 in accuracy and resolution and is probably identical to the DEM of Japan SELENE, but the DEM of Chang'E-1 reveals a new lowest point, clearly lower than that of SELENE. | LI ChunLai1, REN Xin1, LIU JianJun1, ZOU XiaoDuan1, MU LingLi1, WANG JianYu2, SHU Rong2, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, WANG Min1, XU Chun1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, LI JunDuo1 & OUYANG ZiYuan1 1 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China | 2010 | Science China Earth Sciences2010，53，11： | 19 |
| 4 | RESEARCH ON THE EVALUATION METHOD OF FRICTION AND LUBRICATION IN DEEP DRAWING显示文摘The deformation characteristic of bland in deep drawing is discussed. It is pointed out that the friction and lubrication conditions in for drawing are different from that in mechanical motion or machine work or other plastic process. The common test methods in laboratories are analyzed. It shows that though all those test methods can test the friction coefficient, the probe test method is most suitable for the research of friction and lubrication and the process in deep drawing, for this method is identical with the actual work condition either from the test principle or deformation status of the blank. Last the successful application in the deep drawing simulator newly developed the the probe method are intro- duced in detail. | D. N. He, X. F. Yin, H. Z. Thao, D. L*, X. Y. Ruan, J. L. Cheng and J. Y. Jiang 1) Shanghai Jiao Tong University, National Die & Mold CAD E. R. C, Shanghai 200030, China 2) Shanghai Vopkswagen Automotive Company Ltd., Shanghai 201805, China Manuscript re | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 13 |
| 5 | Primary scientific results of Chang'E-1 lunar mission显示文摘The strategic plan for the development of the unmanned Chinese Lunar Exploration Program is characterized by three distinct stages: 'orbiting around', 'landing on' and 'returning from' the Moon. The first Chinese lunar probe, Chang'E-1, which was successfully launched on October 24th, 2007 at Xichang Satellite Launch Center, and guided to crash on the Moon on March 1st, 2009, at 52.36°E, 1.50°S, in the north of Mare Fecunditatis, is the first step towards the 'orbiting around' stage. The Chang'E-1 mission lasted 495 days, exceeding the expected life-span by about four months. A total of 1.37 TB raw data was received from Chang'E-1. It was then processed into 4 TB scientific data products at various levels. Many scientific results have been obtained by analyzing these data, including especially the 'global lunar image from the first Chinese lunar explora- tion mission'. All scientific goals of Chang'E-1 have been achieved. It provides much useful materials for further advances of lunar sciences and planetary chemistry. Meanwhile, these results will serve as a firm basis for future Chinese lunar missions. | OUYANG ZiYuan1,2, LI ChunLai1, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, LIU JianJun1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, ZHAO BaoChang3, WANG JianYu4, YANG JianFeng3, CHANG Jin5, WANG HuanYu6, ZHANG XiaoHui7, WANG ShiJin7, WANG Min1, REN Xin1, MU LingLi1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, ZHENG YongChun1, LI JunDuo1, ZOU XiaoDuan1, XU Chun1, SHI ShuoBiao1, GAO YiFei1 & GAO GuanNan1 1 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China 3 Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China 4 Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China 5 Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008, China 6 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China 7 Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing 100190, China | 2010 | Science China Earth Sciences2010，53，11： | 11 |
| 6 | Partial sequencing of 5' non-coding region of 7 HGV strains isolated from different areas of China显示文摘 | WANG Xing-Tai ZHUANG Hui SONG Hai-Bo Ll He-Min ZHANG Hua-Yuan and YU Yang(National Institute for the Control of bormceutical and BiologicalPriducts, Beijing 100050, China)(Department of Microbiology, Beijing Medical University, Beijing100083, China)(L | 1999 | World Journal of Gastroenterology1999，5，5： | 7 |
| 7 | Relation of ice conditions to climate change in the Bohai Sea of China显示文摘The ice conditions in the Bohai Sea and the northern Huanghai Sea greatly change from year to year with winter climate. Ice only covers below 15% of the the waters during the wannest win-ter, while it covers more than 80% during the coldest winter. Ice observation and data acquisition are outlined in the paper. The ice-covered area, the position of ice edge and the ice grades give indication of the ice conditions. The local climate of the waters can be expressed by using the air temperature of the stations of Dalian and Yingkou. The variation of the ice condition indexes with the monthly mean air temperature at Dalian from 1952 to 2000 is shown, as well. The local climate and ice conditions in the waters are affected by many factors,such as, evolution of the general atmospheric circulation and the solar activity. The delayed correlation between the ice conditions and lots of the affecting factors is analysed in the paper. The ice conditions are continuously mild since the 1990s, that is relative to the tendency of the global warming. The ice condition variation of the Bohai Sea is related to the El Nino event and the sunspot period. The seasonal evolution of the ice conditions is also described in the paper. | Bai Shan, Liu Qinzheng, Wu Huiding I. National Center fOr Marine Environmnt FOrecats, ffeijing l(XX)8I. China. | 2001 | Acta Oceanologica Sinica2001，20，3： | 7 |
| 8 | Suspended sediment flux of river:Wavelet analysis in the Panlong basin of the Upper Red River (Honghe River),China显示文摘这份报纸把小浪分析用于检验变化趋势,多时间规模变化,在上面的红河的 Panlong 盆的推迟的沉积流动(SSF ) 的周期、突然的变化特征,中国。结果显示 SSF 从 1951 ~ 1997 增加了,但是自从 1998,衰退了。SSF 的变化把多时间规模特征和变化在不同时间时期改变了。三周期的时间规模, 4, 7 和 22 年,被决定。22 年的周期的时间规模,是在三次规模之中的最明显的,通过整个研究时期延长了,而第 4-a 7 年的时间规模在某些时间时期仅仅是明显的。分别地有 27 次越过 4 年的时间规模,越过 7 年的时间规模的 16 次和越过 22 年的时间规模的 5 次的突然的变化。根据统计的聚会和气候数据分析,我们断定人的活动是导致了多时间规模的 SSF,而是特征的变化趋势的主要原因,周期、突然的变化被气候变化主要影响。 | DING WenRong~(1,2+) ZHOU Yue~(1,3) L XiXi~4 1 The Faculty of Environment Science and Engineering,Kunming University of Science and Technology,Kunming 650093,China 2 College of Tourism and Geography Science,Yunnan Normal University,Kunming 650092,China 3 Yunnan University of Finance and Economics,Kunming 650221,China 4 Department of Geography,National University of Singapore 119260,Singapore | 2007 | Chinese Science Bulletin2007，52，A02： | 4 |
| 9 | Detection of protein microarrays by oblique-incidence reflectivity difference technique显示文摘Biological microarrays with different proteins and different protein concentrations are detected without external labeling by an oblique-incidence reflectivity difference (OIRD) technique. The initial experiment results reveal that the intensities of OIRD signals can distinguish the different proteins and concentrations of protein. The OIRD technique promises feasible applications to life sciences for label-free and high-throughput detection. | WEN Juan1,LU Heng1,WANG Xu1,YUAN Kun1,L HuiBin1,ZHOU YueLiang1,JIN KuiJuan1,YANG GuoZhen1,LI Wei2 & RUAN KangCheng2 1 Beijing National Laboratory for Condensed Matter Physics,Institute of Physics,Chinese Academy of Sciences,Beijing 100190,China 2 Key Laboratory of Proteomics,Institute of Biochemistry and Cell Biology,Shanghai Institute for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，2： | 4 |
| 10 | Triaxial ellipsoid models of the Moon based on the laser altimetry data of Chang'E-1显示文摘Lunar geodetic parameters, which play an important role in lunar exploration, can be calculated from the gravity and topography data. With the CE-1 altimetry data and LP gravity model, we calculate such geodetic parameters as the principle moment of inertia, the principle inertia axes, equatorial radius, polar radius, mean radius, flattening and offset between center of mass and center of figure (DCOM-COF). According to the CE-1 altimetry data and the above geodetic parameters, a tri-axial ellipsoid (CE-1-LAM-GEO) and a tri-axial level ellipsoid (CE-1-LAM-LEVEL) are calculated individually, providing mass center and figure center offset (DCOM-COF) and parameters more reliable in direction and magnitude. | WANG WenRui1,2,3, LI Fei1, LIU JianJun1, REN Xin2, ZOU XiaoDuan2,3, MU LingLi2, YAN JianGuo1, ZOU YongLiao2, ZHANG HongBo2, Lü Chang2, LIU JianZhong2, ZUO Wei2, SU Yan2, WEN WeiBin2, BIAN Wei2, WANG Min2, LI ChunLai2 & OUYANG ZiYuan2 1 School of Geodesy and Geomatics, Wuhan University, Wuhan 430079, China 2 National Astronomical Observatory of Chinese Academy of Sciences, Beijing 100012, China 3 Graduate School of Chinese Academy of Sciences, Beijing 100049, China | 2010 | Science China Earth Sciences2010，53，11： | 2 |
| 11 | Use of High -performance Liquid Chromatography to Study the Pharmacokinetics of Coloistin Sulfate in Rats Following Intravenous Adminstration显示文摘 | Li -J Milne R W Nation R L | 2003 | Antimicrob Agents Chemother2003，47，5： | 1 |
| 12 | Elevated pulse pres- sure is associated with age-related decline in language ability 显示文摘 | Nation DA Wierenga CE Delano-Wood L | 2010 | J Int Neuropsychol Soc2010，16，5： | 1 |
| 13 | Colistin: the reemerging antibiotic for multidrug-resistant Gram-negative bacterial infections显示文摘 | Li J Nation R L Turnidge J D | 2006 | Lancet Infect Dis2006，6，： | 1 |
| 14 | Myasthenia gravis activities of daily living profile显示文摘 | Wolfe GI Herbelin L Nations SP | 1999 | Neurology1999，52，： | 1 |
| 15 | Pharmacy education in the context of Australian practice显示文摘 | Marriott J Nation R Roller L | 2008 | American Journal of Pharmaceutical Education2008，72，6： | 1 |
| 16 | Pharmacokinetics of Colistin Methanesulfonate and Colistin in a Critically Ⅲ Patient Receiving Continuous Venovenous Hemodiafihration 显示文摘 | Li J Rayner C R Nation R L | 2005 | Antimicrob Agents Chemothe2005，49，11： | 1 |
| 17 | Pharmaeokinetics of Colistin Methanesulphonate and Colistin in Rats Following an Intravenous Dose of Colistin Methanesulphonate 显示文摘 | Li J Miline R W Nation R L | 2004 | J Antimicrob Chemother2004，53，5： | 1 |
| 18 | Word families显示文摘 | Nation P | 1993 | International Journal of Lexicography1993，，3： | 1 |
| 19 | Elevatedpulse pressure is associated with age-related decline inlanguage ability 显示文摘 | Nation D A Wierenga C E Delano-Wood L | 2010 | J Int Neuropsychol Soc2010，16，5： | 1 |
| 20 | Myasthenia gravis activities of daily living profile显示文摘 | Wolfe GI Herbelin L Nations SP | 1999 | Neurology1999，52，： | 1 |
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