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| 1 | 非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。 | R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 | 1998 | 英国医学杂志中文版1998，0，3： | 11 |
| 2 | Trinexapac-ethyl influence on cell membrane thermostability of Kentucky bluegrass leaf tissue显示文摘 | Neil L H Garald L H Roch E G | 2002 | Scinesia Horticulturae2002，92，： | 1 |
| 3 | Effeets of furoquinoline alkaloids on the growth and feeding of two polyphagous lepidopterans显示文摘 | Tara E Saekett G H Neil Towers Murray B Isman | 2007 | Chemoecology2007，17，： | 1 |
| 4 | Gouhy pore pressure estimation from mudrock porosities in Tertiary basins, southeast Asia 显示文摘 | Toby W D H Richard E S Neil R | 1999 | AAPG Bulletin1999，83，7： | 1 |
| 5 | Hyperglycemia and hyperinsulinemia at diagnosis of diabetes and their association with subsequent cardiovascular disease in the United Kingdom prospective diabetes study (UKPDS 47) 显示文摘 | Adler A I Neil H A Manley S E | 1999 | Am Heart J1999，138，51： | 1 |
| 6 | Reliability and validity of a computer--based knowledge mapping system to measure content understanding 显示文摘 | HERL H E O'NEIL JR H F CHUNG G K W K | 1999 | Computer in Human Behavior1999，15，： | 1 |
| 7 | Medication beliefs predict medication adherence in ambulatory patients with decompensated cirrhosis显示文摘AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis.METHODS One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky Medication Adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic Liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. Least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = 0.05.RESULTS Medication adherence was ' High ' in 42 % o f participants, 'Medium' in 37%, and 'Low' in 21%. Compared to patients with 'High' adherence, those with 'Medium' or 'Low' adherence were more likely to report difficulty affording their medications(P < 0.001), lower perception of treatment helpfulness(P = 0.003) and stronger medication concerns relative to medication necessity beliefs(P = 0.003). People with 'Low' adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of 'Low'adherence.CONCLUSION The association between 'Low' adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explored further given the clinical relevance. | Kelly L Hayward Patricia C Valery Jennifer H Martin Antara Karmakar Preya J Patel Leigh U Horsfall Caroline J Tallis Katherine A Stuart Penny L Wright David D Smith Katharine M Irvine Elizabeth E Powell W Neil Cottrell | 2017 | World Journal of Gastroenterology2017，23，40： | 1 |
| 8 | Banana con- tains a diverse array of endogenous badnaviruses 显示文摘 | Andrew D W G Neil E O Glyn H | 2005 | Journal of General Virology2005，86，： | 1 |
| 9 | 1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction显示文摘 | Thomas J Ryan Elliott M Antman Neil H Brooks Robert M Califf L.David Hillis Loren F Hiratzka Elliot Rapaport Barbara Riegel Richard O Russell Earl E Smith W.Douglas Weaver Raymond J Gibbons Joseph S Alpert Kim A Eagle Timothy J Gardner Arthur Garson Gabri | 1999 | Journal of the American College of Cardiology1999，，3： | 1 |
| 10 | Current options for the management of rectal cancer显示文摘 | O'Neil B H Tepper J E | 2007 | Curr Treat Options Oncol2007，8，5： | 1 |
| 11 | CD4^sup +^CD25^sup +^Foxp3^sup +^ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury显示文摘 | D’Alessio Franco R Tsushima Kenji Aggarwal Neil R West Erin E Willett Matthew H Britos Martin F Pipeling Matthew R Brower Roy G Tuder Rubin M McDyer John F King Landon S | 2009 | Journal of Clinical Investigation2009，，10： | 1 |
| 12 | The Addition of MRI and CT Based Stroke and TIA Evaluation Does Not Impact One year Outcomes显示文摘 | Hefzy H Neil E | 2013 | Open Neurol J2013，7，： | 1 |
| 13 | Integrated in- Flight Fault Detection and Accommodation: A Model- Based Study 显示文摘 | Randal T R Kai F G Neil H E | 2007 | Transactions of ASME2007，129，： | 1 |
| 14 | Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus 显示文摘 | Nierman WC Pain A Anderson MJ Wortman JR Kim HS Arroyo J Berriman M Abe K Archer DB Bermejo C Bennett J Bowyer P Chen D Collins M Coulsen R Davies R Dyer PS Farman M Fedorova N Fedorova N Feldblyum TV Fischer R Fosker N Fraser A Garcla JL Garcia MJ Goble A Goldman GH Gomi K Griffith- Jones S Gwilliam R Haas B Haas H Harris D Horiuchi H Huang J Humphray S Jim6nez J Keller N Khouri H Kitamoto K Kobayashi T Konzack S Kulkarni R Kumagai T Lafon A Latgo JP Li W Lord A Lu C Majoros WH May GS Miller BL Mohamoud Y Molina M Monod M Mouyna I Mulligan S Murphy L O'Neil S Paulsen I Pefialva MA Pertea M Price C Pritchard BL Quail MA Rabbinowitsch E Rawlins N Rajandream MA Reichard U Renauld H Robson GD Rodriguez de Cordoba S Rodriguez-Pefia JM Ronning CM Putter S Salzberg SL Sanchez M Sfnchez-Ferrero JC Saunders D Seeger K Squares R Squares S Takeuchi M Tekaia F Turner G Vazquez de Aldana CR Weidman J White O Woodward J Yu JH Fraser C Galagan JE Asai K Machida M Hall N Barrell B Denning DW | 2005 | Nature2005，438，7071： | 1 |
| 15 | Current options for the management of rectaleaneer显示文摘 | O~Neil B H Tepper J E | 2007 | Curt Treat Options Oncol2007，8，5： | 1 |
| 16 | A review of materials, heat transfer and phase change problem for- mulation for latent heat thermal energy storage systems 显示文摘 | FRANCIS A NEIL H PHILIP E | 2010 | Renewable and Sustainable Energy Reviews2010，，14： | 1 |
| 17 | First accuracy evaluation of NIST-F2显示文摘 | Thomas P Heavner Elizabeth A Donley Filippo Levi Giovanni Costanzo Thomas E Parker Jon H Shirley Neil Ashby Stephan Barlow S R Jefferts | 2014 | Metrologia2014，，3： | 1 |
| 18 | Superior vena caval obstruction:detection using CT显示文摘 | Robert E Neil T Robert H | 1985 | Radiology1985，157，2： | 1 |
| 19 | T Cell activation-associated hepatic injury : mediation by tumor necrosis factors and protection by interleukin 6显示文摘 | Mizuhara H O'Neil E Seki N | 1994 | J Exp Med1994，179，5： | 1 |
| 20 | Reduction of murine mammary tumor metastasis by conjugated linoleicacid显示文摘 | Neil E H Debora L Lwari S et al | 2000 | Cancer Letters2000，150，1： | 1 |
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