| 5 | Colorectal cancer risk following appendectomy:a pooled analysis of three large prospective cohort studies显示文摘Dear Editor,Appendectomy is usually performed to treat acute appendicitis although it may also be conducted in the absence of appendicitis when patients suffer from chronic abdominal pain.Resection is also known to mitigate the risk of ulcerative colitis[1],a risk factor for colorectal cancer.The impact of appendectomy on colorectal cancer risk,particularly in the long term,is unclear.The procedurewas initially hypothesized to increase colorectal cancer risk due to decreased immunocompetency. | Joseph A.Rothwell Nagisa Mori Fanny Artaud Agnès Fournier Marco Conte Marie-Christine Boutron-Ruault Simon S.M.Chan Marc J.Gunter Neil Murphy Gianluca Severi | 2022 | Cancer Communications2022，42，5： | 1 |
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