|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gut-microbiome-brain axis:the crosstalk between the vagus nerve,alpha-synuclein and the brain in Parkinson's disease显示文摘This critical review of the literature shows that there is a close link between the microbiome,the gut,and the brain in Parkinson's disease.The vagus nerve,the main component of the parasympathetic nervous system,is involved in the regulation of immune response,digestion,heart rate,and control of mood.It can detect microbiota metabolites through its afferents,transferring this gut information to the central nervous system.Preclinical and clinical studies have shown the important role played by the gut microbiome and gut-related factors in disease development and progression,as well as treatment responses.These findings suggest that the gut microbiome may be a valuable target for new therapeutic strategies for Parkinson's disease.More studies are needed to better understand the underlying biology and how this axis can be modulated for the patient's benefit. | Júlio César Claudino dos Santos Leandro Freitas Oliveira Felipe Micelli Noleto Camilla Teixeira Pinheiro Gusmão Gerly Anne de Castro Brito Glauce Socorro de Barros Viana | 2023 | Neural Regeneration Research2023，18，12： | 2 |
| 2 | Essential oils and their compounds as Aedes aegypti L. (Diptera: Culicidae) larvicides: review显示文摘 | Clarice Noleto Dias Denise Fernandes Coutinho Moraes | 2014 | Parasitology Research2014，，2： | 2 |
| 3 | Refractory remodeling of the microenvironment by abnormal type V collagen,apoptosis,and immune response in non-small cell lung cancer显示文摘 | Souza P Rizzardi F Noleto G | | 0，，02： | 1 |
| 4 | Giant acute epi- dural hematoma after ventriculoperitoneal shunt: a case report and literature review显示文摘 | Noleto G Neville IS Tavares WM | 2014 | Int J Clin Exp Med2014，11，8： | 1 |
| 5 | Chemical Composition and Larvicidal Activity of Essential Oils Extracted from Brazilian Legal Amazon Plants against Aedes aegypti L. (Diptera: Culicidae)显示文摘 | Clarice Noleto Dias Luciana Patrícia Lima Alves Klinger Antonio da Franca Rodrigues Maria Cristiane Aranha Brito Carliane dos Santos Rosa Flavia Maria Mendon?a do Amaral Odair dos Santos Monteiro Eloisa Helena de Aguiar Andrade José Guilherme Soares Maia | 2015 | Evidence-Based Complementary and Alternative Medicine2015，，： | 1 |
| 6 | Giant acute epidural hematoma after ventriculoperitoneal shunt: a case report and literature review显示文摘 | Noleto G Neville IS Tavares WM | 2014 | Int J Clin Exp Med2014，7，： | 1 |
| 7 | Yeast mannan-vanadium(Ⅳ) complexes and their effect on peritoneal macrophages显示文摘 | NOLETO G R MERCE A L R IACOMINI M GORIN P A J OLIVEIRA M B M | 2004 | Carbohydrate Polymers2004，57，2： | 1 |
| 8 | Identification,purification,and some physicochemical properties of staphylococcal enterotoxin C3显示文摘 | Reiser RF Robbins RN Noleto AL | 1984 | Infect Immun1984，45，： | 1 |
| 9 | Nutritional status of zinc and activity super- oxide dismutasc in chronic renal patients undergoing hemodialysis 显示文摘 | Noleto Magalhaes RC Guedes Borges de Araujo C Batista de Sousa Lima V | 2011 | Natr Hosp2011，26，6： | 1 |
| 10 | Nutritional status of zinc and activity superoxide dismu- tase in chronic renal patients undergoing hemodialysis显示文摘 | Noleto Magalhies R Guedes Borges de Araujo C Batista de Sousa Lima V | 2011 | Nutrici6n I-Ios- pitalaria2011，26，6： | 1 |
| 11 | Artemisia absinthium and Artemisia vulgaris : A comparative study of infusion polysaccharides显示文摘 | Marília Locatelli Corrêa-Ferreira Guilhermina Rodrigues Noleto Carmen Lúcia Oliveira Petkowicz | 2013 | Carbohydrate Polymers2013，，： | 1 |
| 12 | Refractory remodeling of the microenvironment by abnormal type V collagen,apoptosis,and immune response in non-small cell lung cancer显示文摘 | Souza P Rizzardi F Noleto G Atanazio M Bianchi O Parra ER | | 0，，： | 1 |
| 13 | Punch‑excised explants of bovine mammary gland to model early immune response to infection显示文摘Background Mammary gland(MG)infections(mastitis)are frequent diseases of dairy cows that affect milk quality,animal welfare and farming profitability.These infections are commonly associated with the bacteria Escherichia coli and Staphylococcus aureus.Different in vitro models have been used to investigate the early response of the MG to bacteria,but the role of the teat in mastitis pathogenesis has received less attention.In this study,we used punch-excised teat tissue as an ex vivo model to study the immune mechanisms that arise early during infection when bacteria have entered the MG.Results Cytotoxicity and microscopic analyses showed that bovine teat sinus explants have their morphology and viability preserved after 24 h of culture and respond to ex vivo stimulation with TLR-agonists and bacteria.LPS and E.coli trigger stronger inflammatory response in teat when compared to LTA and S.aureus,leading to a higher produc-tion of IL-6 and IL-8,as well as to an up-regulation of proinflammatory genes.We also demonstrated that our ex vivo model can be applied to frozen-stored explants.Conclusions In compliance with the 3Rs principle(replacement,reduction and refinement)in animal experimenta-tion,ex vivo explant analyses proved to be a simple and affordable approach to study MG immune response to infec-tion.This model,which better reproduces organ complexity than epithelial cell cultures or tissue slices,lends itself particularly well to studying the early phases of the MG immune response to infection. | Pablo Gomes Noleto Florence B.Gilbert Christelle Rossignol Patricia Cunha Pierre Germon Pascal Rainard Rodrigo Prado Martins | 2023 | Journal of Animal Science and Biotechnology2023，14，6： | 0 |
| 14 | A Pseudo-Stokes Mesh Motion Algorithm显示文摘This work presents a moving mesh methodology based on the solution of a pseudo flow problem.The mesh motion is modeled as a pseudo Stokes problem solved by an explicit finite element projection method.The mesh quality requirements are satisfied by employing a null divergent velocity condition.This methodology is applied to triangular unstructured meshes and compared to well known approaches such as the ones based on diffusion and pseudo structural problems.One of the test cases is an airfoil with a fully meshed domain.A specific rotation velocity is imposed as the airfoil boundary condition.The other test is a set of two cylinders that move toward each other.A mesh quality criteria is employed to identify critically distorted elements and to evaluate the performance of each mesh motion approach.The results obtained for each test case show that the pseudo-flow methodology produces satisfactory meshes during the moving process. | Luciano Goncalves Noleto Manuel N.D.Barcelos Jr. Antonio C.P.Brasil Jr. | 2013 | Advances in Applied Mathematics and Mechanics2013，5，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员