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9篇 您的检索式:作者名="Nuez G"
    题名 作者 年代 出处 被引量
1Genetic and bioclimatic variation in Solanum pimpinellifolium显示文摘Zuriaga E Blanca J M Cordero L Sifres A Blas-Cerdán W G Morales R Nuez F 0,,:1
2The NOD:a signalling molecular that regulates apoptosis and host defense against pathogens显示文摘Inohara N Nuez G 2001Oncogene2001,20,44:1
3Caspases:the proteases of the apoptotic pathway显示文摘Nuez G Benedict MA Hu L 1998Oncogene1998,17,25:1
4The use of Lycopersicon cheesmannii in breeding for salt tolerance tomatoes显示文摘Costa J Nuez F Anastasio G 1990Tomato Genetics and Cooperative1990,40,:1
5Antigen carbohydrate 125 in heart failure: A promising clinical tool显示文摘Nuez J Muana G Nuez E 2011Int J Cardiol2011,150,3:1
6Sensing and reacting to microbes through the inflammasomes显示文摘Franchi L Munoz-Planillo R Nuez G 2012Nat Immunol2012,13,4:1
7Multivariate analysis applied to tomato hybrid production 显示文摘Balasch S Nuez F Palomares G 1984Thero Appl Genet1984,69,:1
8Sex differences in response to kainic acid and estradiol in the hippocampus of newborn rats显示文摘Hilton G D Nuez J L McCarthy M M 2003Neuroscience2003,116,2:1
9Integration of molecular testing for the personalized management of patients with diffuse large B-cell lymphoma and follicular lymphoma显示文摘Diffuse large B-cell lymphoma(DLBCL)and follicular lymphoma(FL)are the most common forms of aggressive and indolent lymphoma,respectively.The majority of patients are cured by standard R-CHOP immunochemotherapy,but 30%–40%of DLBCL and 20%of FL patients relapse or are refractory(R/R).DLBCL and FL are phenotypically and genetically hereterogenous B-cell neoplasms.To date,the diagnosis of DLBCL and FL has been based on morphology,immunophenotyping and cytogenetics.However,next-generation sequencing(NGS)is widening our understanding of the genetic basis of the B-cell lymphomas.In this review we will discuss how integrating the NGS-based characterization of somatic gene mutations with diagnostic or prognostic value in DLBCL and FL could help refine B-cell lymphoma classification as part of a multidisciplinary pathology work-up.We will also discuss how molecular testing can identify candidates for clinical trials with targeted therapies and help predict therapeutic outcome to currently available treatments,including chimeric antigen receptor T-cell,as well as explore the application of circulating cell-free DNA,a non-invasive method for patient monitoring.We conclude that molecular analyses can drive improvements in patient outcomes due to an increased understanding of the different pathogenic pathways affected by each DLBCL subtype and indolent FL vs R/R FL.Ruth Stuckey Hugo Luzardo Henríquez Haridian de la Nuez Melian JoséCarlos Rivero Vera Cristina Bilbao-Sieyro María Teresa Gómez-Casares 2023World Journal of Clinical Oncology2023,14,4:0
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