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| 1 | Ocular Surface Characteristics and Impression Cytology in Patients with Active versus Inactive Thyroid Eye Disease显示文摘Purpose:To compare the clinical findings, tear film function and impression cytology between patients with active and inactive Thyroid Eye Disease (TED). Methods:.A total of 56 patients with TED and 30 controls were recruited in this prospective observational cohort study. TED patients were divided into active TED and inactive TED types according to a seven-point modified formulation of the Clinical Activity Score (CAS). All participants underwent full eye examinations including Ocular Surface Disease Index (OSDI) score, tear film break-up time (TBUT), fluorescein staining and Schirmer I test. Thirty nine patients with thyroid-associated orbitopathy.(TAO) received Nelson's grade with conjunctival impression cytology. Proptosis, palpebral fissure width and lagophthalmos were assessed. Results:.Ocular surface parameters including proptosis, palpebral fissure width and lagophthalmos did not differ between active and inactive TED patients(P>0.05). Both active and inactive TED patients obtained higher fluorescein staining scores, lower TBUT scores and significantly lower Schirmer test scores than those of controls (P<0.001 for all). Additionally, the TBUT score was significantly lower and the OSDI score significantly higher in the active TED group compared with those in the inactive TED group (P<0.001 for both). Impression cytology revealed a higher proportion of grade 2-3 changes in the active TED group compared with the inactive TED group(P<0.001). Conclusion:.Orbital inflammation in TED patients may lead to decreased tear film stability and ocular surface squamous metaplasia. | Nuo Xu Danping Huang Huasheng Yang Zhaoguang Lai Quan Luo | 2012 | Eye Science2012，27，2： | 3 |
| 2 | A CAUSALITY ANALYSIS OF SOCIETAL RISK PERCEPTION AND STOCK MARKET VOLATILITY IN CHINA显示文摘 | Nuo Xu Xijin Tang | 2018 | Journal of Systems Science and Systems Engineering2018，27，5： | 3 |
| 3 | FoxM1 mediated resistance to gefitinib in non-sma cell lung cancer cells显示文摘 | Nuo XU Xin ZHANG Xun WANG Hai-yan GE Xiao-ying WANG David GARFIELD Ping YANG Yuan-lin SONG Chun-xue BAI | 2012 | Acta Pharmacologica Sinica2012，33，5： | 3 |
| 4 | Optimized Bio-inspired Micro-pillar Dry Adhesive and Its Application for an Unmanned Aerial Vehicle Adhering on and Detaching from a Ceiling显示文摘Various bio-inspired dry adhesive materials have been investigated.In this work,lithography and silicon deep etching method were used to fabricate bio-inspired micro-pillar dry adhesive materials of which the parameters,such as side length,Height to Side length Aspect Ratio(HSAR),and inter-pillar Distance to Side length Aspect Ratio(DSAR)were comprehensively studied to obtain a dry adhesive with high adhesion.An orthogonal array method was designed and a series of fabrication experiments were conducted to identify optimum parameters,which resulted in a high normal adhesion of 2.98 N·cm^-2 and a shear adhesion of 9.59 N·cm^-2.An adhesion and desorption device was further designed on basis of the optimum dry adhesive,which enables an Unmanned Aerial Vehicle(UAV)to successfully adhere on and detach from a ceiling.This would allow an UAV to stay aloft for prolonged time,which could be invaluable to many applications,such as energy conservation and aerial detection. | Qingsong He Xianrui Xu Zhiwei Yu Kai Huo Zhaoyang Wang Nuo Chen Xuean Sun Gui Yin Peile Du Yang Li Zhendong Dai | 2020 | Journal of Bionic Engineering2020，17，1： | 2 |
| 5 | Small-molecule fluorescent probes for the detection of carbon dioxide显示文摘During the last few years, the preparation of novel fluorescent probes for the detection of carbon dioxide has attracted considerable attention since carbon dioxide plays extremely important roles in widespread fields including chemical, environmental, clinical analysis, and agri-food industry. This review focuses on the recent advances in the design principles, recognition mechanisms, and preparation of small-molecule fluorescent probes for the selective detection and monitoring of CO_2. Moreover, their properties and functions will be discussed detailedly as well. | Junlong Zhu Peipei Jia Nuo Li Shaoying Tan Junhai Huang Lin Xu | 2018 | Chinese Chemical Letters2018，29，10： | 2 |
| 6 | Biodegradable, Super-Strong, and Conductive Cellulose Macrofibers for Fabric-Based Triboelectric Nanogenerator显示文摘Electronic fibers used to fabricate wearable triboelectric nanogenerator(TENG) for harvesting human mechanical energy have been extensively explored. However, little attention is paid to their mutual advantages of environmental friendliness, mechanical properties, and stability. Here, we report a super-strong, biodegradable, and washable cellulose-based conductive macrofibers, which is prepared by wet-stretching and wet-twisting bacterial cellulose hydrogel incorporated with carbon nanotubes and polypyrrole. The cellulose-based conductive macrofibers possess high tensile strength of 449 MPa(able to lift 2 kg weights), good electrical conductivity(~ 5.32 S cm^(-1)), and excellent stability(Tensile strength and conductivity only decrease by 6.7% and 8.1% after immersing in water for 1 day). The degradation experiment demonstrates macrofibers can be degraded within 108 h in the cellulase solution. The designed fabric-based TENG from the cellulose-base conductive macrofibers shows a maximum open-circuit voltage of 170 V, short-circuit current of 0.8 μA, and output power at 352 μW, which is capable of powering the commercial electronics by charging the capacitors. More importantly, the fabric-based TENGs can be attached to the human body and work as self-powered sensors to effectively monitor human motions. This study suggests the potential of biodegradable, super-strong, and washable conductive cellulose-based fiber for designing eco-friendly fabric-based TENG for energy harvesting and biomechanical monitoring. | Sanming Hu Jing Han Zhijun Shi Kun Chen Nuo Xu Yifei Wang Ruizhu Zheng Yongzhen Tao Qijun Sun Zhong Lin Wang Guang Yang | 2022 | Nano-Micro Letters2022，14，7： | 2 |
| 7 | Comparison of Dynamic Perform- ance of Reinforced Concrete Frame Joint with Different Failure Modes显示文摘 | Yu Jie Chen Lingli Xu Nuo | 2011 | Journal of Shanghai University ( Natural Science)2011，17，5： | 1 |
| 8 | Nanolaminate-based design for UV laser mirror coatings显示文摘With ever-increasing laser power,the requirements for ultraviolet(UV)coatings increase continuously.The fundamental challenge for UV laser-resistant mirror coatings is to simultaneously exhibit a high reflectivity with a large bandwidth and high laser resistance.These characteristics are traditionally achieved by the deposition of laser-resistant layers on highly reflective layers.We propose a“reflectivity and laser resistance in one”design by using tunable nanolaminate layers that serve as an effective layer with a high refractive index and a large optical bandgap.An Al_(2)O_(3)-HfO_(2) nanolaminate-based mirror coating for UV laser applications is experimentally demonstrated using ebeam deposition.The bandwidth,over which the reflectance is >99.5%,is more than twice that of a traditional mirror with a comparable overall thickness.The laser-induced damage threshold is increased by a factor of ~1.3 for 7.6 ns pulses at a wavelength of 355 nm.This tunable,nanolaminate-based new design strategy paves the way toward a new generation of UV coatings for high-power laser applications. | Meiping Zhu Nuo Xu Behshad Roshanzadeh STPBoyd Wolfgang Rudolph Yingjie Chai Jianda Shao | 2020 | Light(Science & Applications)2020，9，1： | 1 |
| 9 | Multi-sensor multi-target passive locating and tracking显示文摘 | Mei Liu Haihao Li Nuo Xu | 2007 | International Journal of Control Automation and Systems2007，5，2： | 1 |
| 10 | Evolution Analysis of Societal Risk Events by Risk Maps显示文摘Event evolution analysis which provides an effective approach to capture the main context of a story from explosive increased news texts has become the critical basis for many real applications,such as crisis and emergency management and decision making.Especially,the development of societal risk events which may cause some possible harm to society or individuals has been heavily concerned by both the government and the public.In order to capture the evolution and trends of societal risk events,this paper presents an improved algorithm based on the method of information maps.It contains an event-level cluster generation algorithm and an evaluation algorithm.The main work includes:1)Word embedding representation is adopted and event-level clusters are chosen as nodes of the events evolution chains which may comprehensively present the underlying structure of events.Meanwhile,clusters that consist of risk-labeled events enable to illustrate how events evolve along the time with transitions of risks.2)One real-world case,the event of'Chinese Red Cross',is studied and a series of experiments are conducted.3)An evaluation algorithm is proposed on the basis of indicators of map construction without massive human-annotated dataset.Our approach for event evolution analysis automatically generates a visual evolution of societal risk events,displaying a clear and structural picture of events development. | Nuo Xu Xjjin Tang | 2020 | Journal of Systems Science and Systems Engineering2020，29，4： | 1 |
| 11 | A magnesium carbo- nate recyclable template to synthesize micro hollow struc- tures at a large scale显示文摘 | Tian Peng Ye Junwei Xu Nuo | 2011 | Chem Commun2011，47，12： | 1 |
| 12 | Temperature com-pensation in bootstrapped current reference source显示文摘 | Jingmei Lu Yi Wang Nuo Xu | | 0，，12： | 1 |
| 13 | Changes in the Urban Surface Thermal Environment of a Chinese Coastal City Revealed by Downscaling MODIS LST with Random Forest Algorithm显示文摘Analysis of the formation and evolution of urban surface thermal environment is crucial for urban planning and improving the environment of a settlement.Qingdao was selected in this study as a typical coastal city undergoing rapid urbanization,and the spatiotemporal dynamic characteristics of its urban surface thermal environment from2010 to 2019 were evaluated.The random forest(RF)algorithm was adopted to obtain its land surface temperature(LST)map with 30-m resolution by downscaling the Moderate Resolution Imaging Spectroradiometer(MODIS)LST product;the remote sensing indices emphasizing different land cover types,LST calculated by the radiative transfer equation,and elevation were used as input variables in the algorithm.The heat island intensity(HII),urban heat island(UHI)volume,and UHI grade were used to analyze the spatiotemporal dynamic characteristics of the urban surface thermal environment in Qingdao.The results show an increasing trend in average HII between 1.1 and 2.52°C in the study area over the past 10 years.The northern city appeared to have the highest UHI volume,while change of the UHI volume in Huangdao District of southwestern Qingdao was the most significant.The areas with high HII have gradually expanded during the last 10 years,and the areas with a 10-yr persistently high HII are distributed mainly in old urban areas with high building density and a dense population.Different factors may influence UHI,such as artificial heat sources,surface heat sources,and hybrid heat sources.Finally,adjusting the urban structure,increasing the vegetated area,and changing building colors are proposed to mitigate UHI in the areas with continuously high HII. | Nuo XU Fan DENG Bingqi LIU Caixia LI Hancong FU Huan YANG Jiahua ZHANG | 2021 | Journal of Meteorological Research2021，35，5： | 1 |
| 14 | Effects of Leptocybe invasa Damage on Chemical Components of Eucalyptus显示文摘[Objective] The aim was to illustrate the relation between Leptocybe invasa and eucalyptus, so as to provide the basis for scientific control of L. invasa. [Method] The chemical components of eucalyptus were extracted by solid phase micro-extraction (SPME) technique and ethanol extraction method, and detected by gas chromatograph-mass spectrometer. The relative contents of various components were determined by area normalization. [Result] When eucalyptus was damaged by L. invasa, not only some substances disappeared, but also new substances were induced. Among 4 induced volatiles, the content of terpinolene was the highest of 37.66%. Eight new chemical substances were also detected from the ethanol extract of damaged leaves, and the content of 3-phenyl-2-propenyl phenpropionate was the highest of 30.95%.[Conclusion] The damage caused by L. invasa had obvious effect on composition and contents of chemical components of eucalyptus. | LV Wen-ling LI Nuo YANG Zhen-de YU Shu-zhong XU Li ZHAO Yan-yan | 2012 | Plant Diseases and Pests2012，3，1： | 1 |
| 15 | A pH-responsive biomimetic drug delivery nanosystem for targeted chemo-photothermal therapy of tumors显示文摘Smart drug delivery nanosystem is significant for tumor treatments due to its possibility of temporally,spatially,and dose-controlled release.However,the therapeutic efficacy of drug delivery nanosystem is often compromised in cancer treatment as the enrichment of therapeutic agents in the reticuloendothelial system.Herein,doxorubicin(DOX)loaded biomimetic drug delivery nanosystem with macrophage cell membrane(MCM)camouflaged,MnFe_(2)O_(4)-DOX-MCM nanocube(NC),is developed for cancer treatment with tumor targeting,pH-stimuli drug release,and chemo-photothermal therapeutic effects.The nanosystem shows the capability of immune escape and enhanced cellular uptake of cancer cells due to the MCM decoration.Acid-labile bond between the MnFe2O4 NCs and DOX remains stable at physiological condition and release drugs immediately in response to the endo-/lysosome pH stimuli.Meanwhile,the photothermal effect of the nanosystem destroys tumor tissue,which further promotes chemotherapeutic efficacy.In vivo results demonstrate the tumor homing ability and produce a notable synergistic therapeutic effect of the NCs.Thus,biomimetic pH-responsive drug delivery nanosystem,MnFe_(2)O_(4)-DOX-MCM NCs,is an effective nanoplatform,which might be potential application for cancer synergistic treatment. | Yanmin Ju Zhiyi Wang Zeeshan Ali Hongchen Zhang Yazhou Wang Nuo Xu Hui Yin Fugeng Sheng Yanglong Hou | 2022 | Nano Research2022，15，5： | 1 |
| 16 | Histological and ultrastructural study on the medial canthal ligament of blepharophimosis, ptosis and epicanthus inversus syndrome显示文摘背景 Blepharophimosis 下垂蒙古内此赘皮 inversus 症候群(BPES ) 是稀罕先天的眼的混乱,包括双边的下垂由先天的眼皮畸形性描绘了,在内部 canthi 之间的水平眼皮裂缝,蒙古内此赘皮 inversus,和增加的距离弄短。在这研究,我们与 BPES.Methods 学习了病人的中间的 canthal 系带的组织学的结构和超微结构从 2006 年 3 月在中山眼的中心收到了整形外科到 2008 年 1 月的有 BPES 的三十个病人被学习。与平均年龄有 17 男性和 13 女性(8.73 ?@ | HUANG Dan-ping ZHUO Ye-hong CAI Jian-hao XU Nuo ZHONG Xiu-feng YU Yang-yang LAI Zhao-guang GONG Di GE Jian | 2009 | Chinese Medical Journal2009，，22： | 1 |
| 17 | Polar Gini Curve:A Technique to Discover Gene Expression Spatial Patterns from Single-cell RNA-seq Data显示文摘In this work,we describe the development of Polar Gini Curve,a method for characterizing cluster markers by analyzing single-cell RNA sequencing(scRNA-seq)data.Polar Gini Curve combines the gene expression and the 2D coordinates(“spatial”)information to detect patterns of uniformity in any clustered cells from scRNA-seq data.We demonstrate that Polar Gini Curve can help users characterize the shape and density distribution of cells in a particular cluster,which can be generated during routine scRNA-seq data analysis.To quantify the extent to which a gene is uniformly distributed in a cell cluster space,we combine two polar Gini curves(PGCs)—one drawn upon the cell-points expressing the gene(the“foreground curve”)and the other drawn upon all cell-points in the cluster(the“background curve”).We show that genes with highly dissimilar foreground and background curves tend not to uniformly distributed in the cell cluster—thus having spatially divergent gene expression patterns within the cluster.Genes with similar foreground and background curves tend to uniformly distributed in the cell cluster—thus having uniform gene expression patterns within the cluster.Such quantitative attributes of PGCs can be applied to sensitively discover biomarkers across clusters from scRNA-seq data.We demonstrate the performance of the Polar Gini Curve framework in several simulation case studies.Using this framework to analyze a real-world neonatal mouse heart cell dataset,the detected biomarkers may characterize novel subtypes of cardiac muscle cells.The source code and data for Polar Gini Curve could be found at http://discovery.informatics.uab.edu/PGC/or https://figshare.com/projects/Polar_Gini_Curve/76749. | Thanh Minh Nguyen Jacob John Jeevan Nuo Xu Jake Y.Chen | 2021 | Genomics, Proteomics & Bioinformatics2021，19，3： | 1 |
| 18 | Influences of Co-Flow and Counter-Flow Modes of Reactant Flow Arrangement on a PEMFC at Start-Up显示文摘To investigate the influences of co-flowand counter-flowmodes of reactant flowarrangement on a proton exchange membrane fuel cell(PEMFC)during start-up,unsteady physical and mathematical models fully coupling the flow,heat,and electrochemical reactions in a PEMFC are established.The continuity equation and momentum equation are solved by handling pressure-velocity coupling using the SIMPLE algorithm.The electrochemical reaction rates in the catalyst layers(CLs)of the cathode and anode are calculated using the Butler-Volmer equation.The multiphase mixture model describes the multiphase transport process of gas mixtures and liquid water in the fuel cell.After validation,the influences of co-flow and counter-flow modes on the PEMFC performance are investigated,including the evolution of the current density,flow field,temperature field,and reactant concentration field during start-up,as well as the steady distribution of the current density,reactant concentration,andmembrane water content when the start-up stabilizes.Co-flow and counter-flow modes influence the current density distribution and temperature distribution.On the one hand,the co-flow mode accelerates the start-up process of the PEMFC and leads to a more evenly distributed current density than the counter-flow mode.On the other hand,the temperature difference between the inlet and outlet sections of the cell is up to 10.1℃ under the co-flow mode,much larger than the 5.0℃ observed in the counter-flow mode.Accordingly,the counter-flowmode results in a more evenly distributed temperature and a lower maximum temperature than the co-flow case.Therefore,in the flow field design of a PEMFC,the reactant flow arrangements can be considered to weigh between better heat management and higher current density distribution of the cell. | Qianqian Shao Min Wang Nuo Xu | 2024 | Computer Modeling in Engineering & Sciences2024，139，5： | 0 |
| 19 | Towards a tailored indoor horticulture:a functional genomics guided phenotypic approach显示文摘As indoor horticulture gathers momentum,electric(also termed artificial)lighting systems with the ability to generate specific and tunable wavelengths have been developed and applied.While the effects of light quality on plant growth and development have been studied,authoritative and reliable sets of light formulae tailored for the cultivation of economically important plants and plant traits are lacking as light qualities employed across laboratories are inconsistent.This is due,at least in part,to the lack of molecular data for plants examined under electric lights in indoor environments.It has hampered progress in the field of indoor horticulture,in particular,the transition from small-scale indoor farming to commercial plant factories.Here,we review the effects of light quality on model and crop plants studied from a physiological,physical and biochemical perspective,and explain how functional genomics can be employed in tandem to generate a wealth of molecular data specific for plants cultivated under indoor lighting.We also review the current state of lighting technologies in indoor horticulture specifically discussing how recent narrow-bandwidth lighting technologies can be tailored to cultivate economically valuable plant species and traits.Knowledge gained from a complementary phenotypic and functional genomics approach can be harvested not only for economical gains but also for sustainable food production.We believe that this review serves as a platform that guides future light-related plant research. | Claudius Marondedze Xinyun Liu Shihui Huang Cynthia Wong Xuan Zhou Xutong Pan Huiting An Nuo Xu Xuechen Tian Aloysius Wong | 2018 | Horticulture Research2018，5，1： | 0 |
| 20 | Chemical cross-linking and mechanically reinforced carbon network constructed by graphene boosts potassium ion storage显示文摘Carbon-based electrodes of potassium-ion batteries are of great research interest ascribed to their low cost and environmentally friendly distinctions.However,traditional carbon materials usually exhibit weak mechanical properties and incomplete crosslinking,resulting in poor stability and electrochemical performance.Herein,we report a new strategy for modifying reduced graphene oxide into a uniform few-layer structure through a sol–gel method combined with acid etching treatment.The obtained chemical cross-linking and mechanically reinforced carbon network constructed by graphene(CNCG)demonstrates excellent electrochemical and mechanical properties.Adopted as a free-standing anode(~7 mg·cm^(−2))for potassium ion battery,the asachieved CNCG delivers a high reversible specific capacity of 317.7 mAh·g^(−1) at a current density of 50 mA·g^(−1) and admirable cycle stability(208.4 mAh·g^(−1) at 50 mA·g^(−1) after 500 cycles).The highly reversible structural stability and fully cross-linked properties during potassiation are revealed by ex-situ characterization.This work provides new ideas for the synthesis of new carbon materials and the development of high-performance electrodes. | Chenxu Wang Ruohan Yu Wen Luo Wencong Feng Yuanhao Shen Nuo Xu Liqiang Mai | 2022 | Nano Research2022，15，10： | 0 |
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