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| 1 | Effects of melatonin on lipid peroxidation and antioxidant enzymes in streptozotocin-induced diabetic rat testis显示文摘瞄准:为了在 streptozotocin (STZ ) 的阴囊的组织每氧化(LPO ) 和抗氧化剂酶的活动在类脂化合物上检验 melatonin 治疗的效果,导致了糖尿病的老鼠。方法:26 只雄的老鼠随机如下被划分成三个组:组我,控制,非糖尿病的老鼠(n = 9 ) ;组 II,导致 STZ 的、未经治疗的糖尿病的老鼠(n = 8 ) ;组 III,导致 STZ,对待 melatonin (10 mg/kg 的剂量。白天) 糖尿病的老鼠(n = 9 ) 。后面的 8 星期的 melatonin 处理,所有老鼠被使麻木然后被打死把睾丸从阴囊移开。结果:作为与组相比我,在老鼠组 II 的阴囊的纸巾, malondialdehyde ( MDA )的增加的层次( P <
0.01 )并且超级氧化物歧化酶(草皮)( P <
0.01 )象过氧化氢酶(猫)的减少的层次一样( P <
0.01 )并且谷胱甘肽过氧化物酶( GSH-Px )( P >
0.05 )被发现。相反作为与组 II 相比,在老鼠组 III 的阴囊的纸巾, MDA 的层次减少了(但是这减少不是重要的, P >
0.05 ) 并且草皮(P <
0.01 ) 象猫一样(P <
0.05 ) 增加。GSH-Px 没被任何处理影响。Melatonin 显著地没影响糖尿病的组的提高的葡萄糖集中。在学习的结束,借助于身体和阴囊的重量在对待 melatonin 的组和未经治疗的组之间没有有效差量。结论:糖尿病增加氧化应力, melatonin 每氧化和力量禁止类脂化合物调整糖尿病的老鼠睾丸的抗氧化剂酶的活动。 | Abdullah Armagan EfkanUz H.RamazanYilmaz SedatSoyupek TaylanOksay Nurten Ozcelik | 2006 | Asian Journal of Andrology2006，8，5： | 17 |
| 2 | Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver显示文摘AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sati-va (NS) treatment group (Group 3). All rats underwent hepatic ischemia for 45 min followed by 60 min period of reperfusion. Rats were intraperitoneally infused with only 0.9% saline solution in group 2. Rats in group 3 received NS (0.2 mL/kg) intraperitoneally, before isch-emia and before reperfusion. Blood samples and liver tissues were harvested from the rats, and then the rats were sacrifi ced. Serum aspartate aminotransfera-se (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined. Total antioxidant capacity (TAC), catalase (CAT), total oxida-tive status (TOS), oxidative stress index (OSI) and my-eloperoxidase (MPO) in hepatic tissue were measured. Also liver tissue histopathology was evaluated by light microscopy. RESULTS: The levels of liver enzymes in group 3 weresignifi cantly lower than those in the group 2. TAC in liver tissue was significantly higher in group 3 than in group 2. TOS, OSI and MPO in hepatic tissue were signifi cantly lower in group 3 than the group 2. Histo-logical tissue damage was milder in the NS treatment group than that in the control group. CONCLUSION: Our results suggest that Nigella sa-tiva treatment protects the rat liver against to hepatic ischemia-reperfusion injury. | Fahrettin Yildiz Sacit Coban Alpaslan Terzi Mustafa Ates Nurten Aksoy Hale Cakir Ali Riza Ocak Muharrem Bitiren | 2008 | World Journal of Gastroenterology2008，14，33： | 8 |
| 3 | Keratinocyte 生长 factor-2 和自体同源的浆液加强处于在老鼠的角膜损坏的间充质的干细胞的再生效果显示文摘AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells(MSCs)cultured with or without keratinocyte growth factor(KGF-2)and autologous serum(AS)on amniotic membrane(AM).Many patients are blind and devastated by severe ocular surface diseases due to limbal stem cell deficiency.Bone marrow-derived MSCs are potential sources for cellbased tissue engineering to repair or replace the corneal tissue,having the potential to differentiate to epithelial cells.METHODS:The study included 5 groups each including 10 female'Sprague Dawley'rats in addition to20 male rats used as bone marrow donors.Group I rats received AM+MSCs,Group II rats AM+MSCs cultured with KGF-2,Group III rats AM+MSCs cultured with KGF-2+AS,Group IV rats only AM and Group V rats,none.AS was derived from blood drawn from male rats and bone marrow was obtained from the femur and tibia bones of the same animals.Therapeutic effect was evaluated with clinical,histopathological and immunohistochemical assessment.MSC engraftment was demonstrated via detection of donor genotype(Y+)in the recipient tissue(X)with polymerase chain reaction.RESULTS:Corneal healing was significantly better in Groups I-III rats treated with MSC transplantation compared to Group IV and Group V rats with supportive treatment only.The best results were obtained in Group III rats with 90%transparency,70%lack of neovascularization,and 100%epithelium damage limited to less than 1/4 of cornea.CONCLUSION:We suggest that culture of MSCs with KGF-2 and AS on AM is effective in corneal repair in case of irreversible damage to limbal stem cells. | Ferda Alpaslan Pinarli Gülsen Okten Umit Beden Tunc Fisgin Mehmet Kefeli Nurten Kara Feride Duru Leman Tomak | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 4 |
| 4 | Gastrointestinal endoscopy in pregnancy显示文摘Gastrointestinal endoscopy has a major diagnostic and therapeutic role in most gastrointestinal disorders; however, limited information is available about clinical efficacy and safety in pregnant patients. The major risks of endoscopy during pregnancy include potential harm to the fetus because of hypoxia, premature labor, trauma and teratogenesis. In some cases, endoscopic procedures may be postponed until after delivery. When emergency or urgent indications are present, endoscopic procedures may be considered with some precautions. United States Food and Drug Administration category B drugs may be used in low doses. Endoscopic procedures during pregnancy may include upper gastrointestinal endoscopy, percutaneous endoscopic gastrostomy, sigmoidoscopy, colonoscopy, enteroscopy of the small bowel or video capsule endoscopy, endoscopic retrograde cholangiopancreatography and endoscopic ultrasonography. All gastrointestinal endoscopic procedures in pregnant patients should be performed in hospitals by expert endoscopists and an obstetrician should be informed about all endoscopic procedures. The endoscopy and flexible sigmoidoscopy may be safe for the fetus and pregnant patient, and may be performed during pregnancy when strong indications are present. Colonoscopy for pregnant patients may be considered for strong indications during the second trimester. Although therapeutic endoscopic retrograde cholangiopancreatography may be considered during pregnancy, this procedure should be performed only for strong indications and attempts should be made to minimize radiation exposure. | Nurten Savas | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 5 | Cells and material-based strategies for regenerative endodontics显示文摘 The carious process leads to inflammation of pulp tissue.Current care options include root canal treatment or apexification.These procedures,however,result in the loss of tooth vitality,sensitivity,and healing.Pulp capping and dental pulp regeneration are continually evolving techniques to regenerate pulp tissue,avoiding necrosis and loss of vitality.Many studies have successfully employed stem/progenitor cell populations,revascularization approaches,scaffolds or material-based strategies for pulp regeneration.Here we outline advantages and disadvantages of different methods and techniques which are currently being used in the field of regenerative endodontics.We also summarize recent findings on efficacious peptide-based materials which target the dental niche.. | Zain Siddiqui Amanda M.Acevedo-Jake Alexandra Griffith Nurten Kadincesme Kinga Dabek Dana Hindi Ka Kyung Kim Yoshifumi Kobayashi Emi Shimizu Vivek Kumar | 2022 | Bioactive Materials2022，7，8： | 2 |
| 6 | The cagA status of Helicobacter pylori isolates from dyspeptic children in Turkey显示文摘 | ?nci Nur Salt?k Hülya Demir Doruk Engin ?zge Darka Ertun? Yakut Aky?n Nurten Ko?ak | 2003 | FEMS Immunology and Medical Microbiology2003，，3： | 1 |
| 7 | Combined Spinal-Epidural Anesthesia with Epidural Volume Extension causes a Higher Level of Block than Single-Shot Spinal Anesthesia显示文摘 | Canan Salman Nurten Kayacan Fatma Ertu?rul Zekiye B?gat Bilge Karsl? | 2013 | Brazilian Journal of Anesthesiology2013，，3： | 1 |
| 8 | The effects of remifentanil and alfentanil-based total intravenous anesthesia (TIVA) on the en- docrine response to abdominal hysterectomy 显示文摘 | Semra D Suleyman GL Nurten A | 2004 | J Clin Anesth2004，16，5： | 1 |
| 9 | Improvement of dissolution properties of furosemide by complexation with β - cyclodextrin显示文摘 | Nurten O Sefika O | 1998 | Drug Dev Ind Pharm1998，24，1： | 1 |
| 10 | Design of a controlled release osmotic pump system of ibuprofen 显示文摘 | NURTEN O JFILIDE S | 1997 | International Journal of Pharmaceutics1997，，158： | 1 |
| 11 | Implications for Degenerative Disorders: Antioxidative Activity, Total Phenols, Flavonoids, Ascorbic Acid, β-Carotene and β-Tocopherol in Aloe vera显示文摘 | Nurten Ozsoy Eda Candoken Nuriye Akev | 2009 | Oxidative Medicine and Cellular Longevity2009，，2： | 1 |
| 12 | Improvement of β-cyclodextrin 显示文摘 | Nurten Ozdemir Sefika Ordu | 1998 | Drug Dev Ind Pharm1998，24，1： | 1 |
| 13 | The effects of remifentail and acfentanil - based total intravenous anesthesia(TIVA) on the endosrine response to abdominal hysterectomy 显示文摘 | Samra Demirbilek Suleyman Ganidagli Nurten Aksoy | 2004 | Journal of Clinical Anesthesia2004，16，： | 1 |
| 14 | Physical and functional interactions between Werner syndrome heliease and mlsmateh-repair initiation factors显示文摘 | Nurten S Radhakrishnan K Tobias D | 2007 | Nucleic Aeids Res2007，35，17： | 1 |
| 15 | Improvement of dissolution properties of Furosemide by complexation with β-cyclodextrin显示文摘 | Nurten O Sefika O | 1998 | drug devInd pharm1998，24，1： | 1 |
| 16 | Factors Predicting Outcome of Balloon Dilatation in Achalasia显示文摘 | ülkü Da?l? Sedef Kuran Nurten Sava? Yasemin ?zin Canan Alk?m Fuat Atalay Burhan ?ahin | 2009 | Digestive Diseases and Sciences2009，，6： | 1 |
| 17 | Numerical investigation of a water flow in a rib roughened channel by using Reynolds stress model显示文摘 | SEYFETTIN B MERAL B NURTEN V | 2009 | International Journal of Computational Fluid Dynamics2009，22，： | 1 |
| 18 | Effects of Caffeic Acid Phenethyl Ester on Lipid Peroxidation and Antioxidant Enzymes in Diabetic Rat Heart 显示文摘 | HUSEYIN O NURTEN O H RAMAZAN Y | 2005 | Clin Biochem2005，38，2： | 1 |
| 19 | Structure-activity relationship studies on aza analogues of illudins显示文摘 | Refik Ozkan Nurten Tezer | 2001 | Journal of Molecular Structure: THEOCHEM2001，572，13： | 1 |
| 20 | Ochratoxin A in human serum samples collected in Isparta-Turkey from healthy individuals and individuals suffering from different urinary disorders显示文摘 | Nurten Ozcelik Alim Kos Demet Soysal | 2001 | Toxicology Letters2001，121，： | 1 |
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