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您的检索式：作者名="O.CARVALHO"
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| 1 | 选择激光熔化、热压缩和传统铸造工艺加工的Ti6Al4V生物合金的磨损行为显示文摘本研究的主要目的是研究加工工艺对Ti6Al4V生物医学合金显微组织、硬度和摩擦学行为(摩擦和磨损行为)的影响。加工工艺包括传统铸造、热压缩和选择激光熔化。采用X射线衍射技术、维氏硬度测试和Ti6Al4V/Al_2O_3摩擦副的往复式球板磨损实验对Ti6Al4V生物医学合金的冶金、力学和摩擦学性能进行表征。结果表面,加工工艺路线对合金的显微组织、硬度和磨损行为的影响很大。采用选择激光熔化工艺获得的Ti6Al4V合金具有最高的硬度和最佳的耐磨性能,这是由于与采用热压缩和传统铸造工艺相比,选择激光熔化工艺具有显著不同的冷却速率,这使得合金具有明显不同的显微组织。本研究评估和证明选择激光熔化工艺在制备高耐磨Ti6Al4V生物植入体方面具有较大潜力。 | F.BARTOLOMEU M.BUCIUMEANU E.PINTO N.ALVES F.S.SILVA O.CARVALHO G.MIRANDA | 2017 | Transactions of Nonferrous Metals Society of China2017，27，4： | 11 |
| 2 | NiTi laser textured implants with improved in vivo osseointegration:An experimental study in rats显示文摘Laser surface texturing is a versatile approach for manufacturing implants with suitable surfaces for os-seointegration.This work explores the use of laser to fabricate NiTi textured implants,testing two dif-ferent groove-based designs.Their performance was evaluated in vivo through implantation in Sprague Dawley rats’femur,being then analyzed after 4 and 12 weeks of implantation.Push-out experiments and histological characterization allowed to assess bone-implant bond and osseointegration and to compare the laser textured solutions with non-textured NiTi.Histology showed that,at 4 weeks of implantation,mainly immature woven bone was present whilst at 12 weeks a more mature bone had developed.Con-sidering the largest implantation time(12 weeks),results showed extraction forces considerably higher for textured implants(G2 and G3).Moreover,when comparing G2 and G3,it was found that G2(having the highest textured surface area)displayed the maximum extraction force among all groups,with an increase of 212%when compared to non-textured implants(G1).These results prove that the design and manufacturing technology are effective to promote an im-proved bone-implant bond,aiming the development of orthopedic implants. | M.M.Costa A.Miranda F.Bartolomeu O.Carvalho S.Matos G.Miranda F.S.Silva | 2022 | Journal of Materials Science & Technology2022，，19： | 0 |
| 3 | Mechanical stimulation devices formechanobiology studies:a market,literature,and patents review显示文摘Significant advancements in various research and technological fields have contributed to remarkable findings on the physiological dynamics of the human body.Tomore closely mimic the complex physiological environment,research has moved from two-dimensional(2D)culture systems to more sophisticated three-dimensional(3D)dynamic cultures.Unlike bioreactors or microfluidic-based culture models,cells are typically seeded on polymeric substrates or incorporated into 3D constructs which are mechanically stimulated to investigate cell response to mechanical stresses,such as tensile or compressive.This review focuses on the working principles of mechanical stimulation devices currently available on the market or custom-built by research groups or protected by patents and highlights the main features still open to improvement.These are the features which could be focused on to perform,in the future,more reliable and accurate mechanobiology studies. | F.Melo-Fonseca O.Carvalho M.Gasik G.Miranda F.S.Silva | 2023 | Bio-Design and Manufacturing2023，6，3： | 0 |
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