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| 1 | Mutations in |NVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left - right axis determination显示文摘 | OTI'O E A SCHERMER B OBARA T | 2003 | Nat Genet2003，34，4： | 1 |
| 2 | LAMP using a disposable pock et warmer for anthrax detection, a highly mobile and reliable method for anti-bioterrorism显示文摘 | Hatano B Maki T Obara T | 2010 | Jpn J Infect Dis2010，63，1： | 1 |
| 3 | LAMP using a disposable pock- et warmer or anthrax detection, a highly mobile and reliable method {or anti-bioterrorism显示文摘 | Hatano B Maki T Obara T | 2010 | Jpn J Infect Dis2010，63，1： | 1 |
| 4 | Changes in chemical constituents of kiwifruit during postharvest ripening显示文摘 | Matsumoto S Obara T Luh B S | 1983 | J Food Sci1983，48，： | 1 |
| 5 | LAMP using a disposable Pocket Warmer for Anthrax detection, a highly mobile and reliable method for Anti-Bioterrorism 显示文摘 | Hatano B Maki T Obara T | 2010 | Jpn J Infect Dis2010，63，1： | 1 |
| 6 | a3131 integrins regulate CD151 complex assembly and membrane dynamics in carcinoma ceils within 3D environments 显示文摘 | Scales TM Jayo A Obara B | 2013 | Oncogene2013，32，34： | 1 |
| 7 | A new algorithm using image colour system transformation for rock grain segmentation 显示文摘 | OBARA B | 2007 | Mineralogy and Petrology2007，91，： | 1 |
| 8 | LAMP Using a Disposable Pocket Warmer for Anthrax Detection,a Highly Mobile and Reliable Method for Anti-Bioterrorism显示文摘 | Hatano B Maki T Obara T Fukumoto H Hagisawa K Matsushita Y Okutani A Bazartseren B Inoue Satoshi Sata T Katano H | | 0，，： | 1 |
| 9 | Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of the primary cilia and left-right axis determination显示文摘 | Otto O Schermer B Obara T | 2003 | Nature Genetics2003，34，： | 1 |
| 10 | Mutations in IN- VS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination显示文摘 | Otto EA Schermer B Obara T et a | 2003 | Nat Genet2003，34，： | 1 |
| 11 | Contrast-indepen- dent curvilinear structure detection in biomedical images显示文摘 | Obara B Fricker M Gavaghan D | 2012 | IEEE Trans on Image Processing2012，21，5： | 1 |
| 12 | Local peripheral effects of mu-opioid receptor agonists in neuropathic pain in rats显示文摘 | Obara I Przewlocki R Przewlocka B | 2004 | Neurosci Lett2004，360，12： | 1 |
| 13 | Changes in chemical constituents of kiwifruit during postharvest ripening 显示文摘 | Matsumoto S Obara T Luh B S | 1983 | Food Sci1983，48，： | 1 |
| 14 | Changes in chemical constituents of kiwifruit during posthavest ripening显示文摘 | Matsumoto S Obara T Luh B S | 1983 | Food Sci1983，48，： | 1 |
| 15 | LAMP Using a Disposable Pocket Warmer for Anthrax Detection,a Highly Mobile and Reliable Method for Anti-Bioterrorism显示文摘 | Hatano B Maki T Obara T | | 0，，01： | 1 |
| 16 | A biosegmentation benchmark for evaluation of bioimage analysis methods显示文摘 | Gelasca E D Obara B Fedorov D | 2009 | BMC Bioinformatics2009，10，11： | 1 |
| 17 | A new algorithm using image colour system transformation for cutting grain segmentation显示文摘 | Obara B | 2007 | Mineralogy and Petrology2007，91，34： | 1 |
| 18 | 2009年日本骏河湾地震后东海俯冲带上应力转移之探讨显示文摘日本西南部位于菲律宾海俯冲板块和欧亚上冲板块交界处。1944年和1946年,东南海和南海分别发生一次8级大逆冲型地震,但与该板块边界相邻的东海却仍保持闭锁状态[1]。因此,东海地区有可能会发生一次大逆冲型地震。2009年,骏河湾发生6.4级地震,地震位于菲律宾海俯冲板块内,靠近东海地区。在此,我们利用断层滑动模型来研究由骏河湾地震引起的应力变化[2]对东海地区的影响。我们发现在这次地震之后,板块边界的地震活动发生率有所上升。东海地区推测的强闭锁地段大都位于应力逐渐增大的地区。其中一小块闭锁地段的破裂——发生在地震应力达到临界值之后——就会引起整个东海地区的破裂,最终引发一场大逆冲型地震。 | Aoi S Enescu B Suzuki W Asano Y Obara K Kunugi T Shiomi K 王峰(译) 左玉玲(校) | 2010 | 国际地震动态2010，，10： | 1 |
| 19 | Analysis of fungal networks显示文摘 | HEATON L OBARA B ( RAU V | 2012 | British Mycological Society2012，2612，29： | 1 |
| 20 | Imaging assessment of photosensitizer emission induced by radionuclide-derived Cherenkov radiation using charge-coupled device optical imaging and long-pass filters显示文摘BACKGROUND Radionuclides produce Cherenkov radiation(CR),which can potentially activate photosensitizers(PSs)in phototherapy.Several groups have studied Cherenkov energy transfer to PSs using optical imaging;however,cost-effectively identifying whether PSs are excited by radionuclide-derived CR and detecting fluorescence emission from excited PSs remain a challenge.Many laboratories face the need for expensive dedicated equipment.AIM To cost-effectively confirm whether PSs are excited by radionuclide-derived CR and distinguish fluorescence emission from excited PSs.METHODS The absorbance and fluorescence spectra of PSs were measured using a microplate reader and fluorescence spectrometer to examine the photo-physical properties of PSs.To mitigate the need for expensive dedicated equipment and achieve the aim of the study,we developed a method that utilizes a chargecoupled device optical imaging system and appropriate long-pass filters of different wavelengths(manual sequential application of long-pass filters of 515,580,645,700,750,and 800 nm).Tetrakis(4-carboxyphenyl)porphyrin(TCPP)was utilized as a model PS.Different doses of copper-64(^(64)CuCl_(2))(4,2,and 1 mCi)were used as CR-producing radionuclides.Imaging and data acquisition were performed 0.5 h after sample preparation.Differential image analysis was conducted by using ImageJ software(National Institutes of Health)to visually evaluate TCPP fluorescence.RESULTS The maximum absorbance of TCPP was at 390-430 nm,and the emission peak was at 670 nm.The CR and CRinduced TCPP emissions were observed using the optical imaging system and the high-transmittance long-pass filters described above.The emission spectra of TCPP with a peak in the 645-700 nm window were obtained by calculation and subtraction based on the serial signal intensity(total flux)difference between^(64)CuCl_(2)+TCPP and^(64)CuCl_(2).Moreover,the differential fluorescence images of TCPP were obtained by subtracting the^(64)CuCl_(2)image from the^(64)CuCl_(2)+TCPP image.The experimental results considering different^(64)CuCl_(2)doses showed a dosedependent trend.These results demonstrate that a bioluminescence imaging device coupled with different longpass filters and subtraction image processing can confirm the emission spectra and differential fluorescence images of CR-induced TCPP.CONCLUSION This simple method identifies the PS fluorescence emission generated by radionuclide-derived CR and can contribute to accelerating the development of Cherenkov energy transfer imaging and the discovery of new PSs. | Winn Aung Atsushi B Tsuji Kazuaki Rikiyama Fumihiko Nishikido Satoshi Obara Tatsuya Higashi | 2023 | World Journal of Radiology2023，15，11： | 0 |
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