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42篇 您的检索式:作者名="Ohdo"
    题名 作者 年代 出处 被引量
1Elevated plasma cryofibrinogen in patients with active inflammatory bowel disease is morbigenous显示文摘瞄准:在活跃的煽动性的肠疾病(IBD ) 调查冷沉纤维蛋白(CF ) 的角色。方法:CF 是在 284 个题目的 assayed:61 与活跃并且 63 与不活跃的 ulcerative (UC ) , 45 有 proctocolectomy, 35 与活跃并且 20 与不活跃的 Crohn 的疾病(CD ) , 40 与另外的疾病和 20 健康控制。胰岛素禁止者(TI ) 和 TI 抗体(TI-Ab ) 被 ELISA 在血浆和 CF 建筑群测量。结果:在活跃 UC 的 CF 与所有另外的组(c2<0.001 ) 相比惊人地高。同样, CF 比在不活跃的 CD 或在控制(c2<0.01 ) 在活跃 CD 是显著地更高的。在 UC,高 CF 和 TI-Ab 与对操作的需要被联系。进一步,在血浆的高 CF, CF/fibrinogen 比率,低 TI 和高 TI-Ab 与疾病活动或倔强被联系到药。提高的 CF 没与相似 C 反应的蛋白质和白血房间除了红细胞沉降率数的尖锐反应物被联系,建议那提高的 CF 不是急性炎的后果。结论:在活跃 IBD 的提高的 CF 看起来是致病。CF 经由二主要机制支持 IBD, TI (一种反煽动性的物质) 熄灭并且损害由形成蛋白质总数的微脉管的灌注。CF 可以也用作长期的 IBD 的一个简历标记。另外的研究被保证充分在 IBD 评估 CF 的角色,结果应该贡献 IBD 的致病的更好的理解。Koji Sawada Ryouki Takahashi Abbi R Saniabadi Maiko Ohdo Takashi Shimoyama 2006World Journal of Gastroenterology2006,12,10:7
2Statin inhibits the ex-pression of secretory phospholipase A2 and subsequentmonocyte chemoattractant protein-1 in human endothelialcells显示文摘Sonoki K Iwase M Ohdo S 2014J Cardiovasc Pharmacol2014,64,6:1
3Population based investigation of relative clearance of digoxin in Japanese patients by multiple trough screen analysis: an update 显示文摘Yukawa E Honda T Ohdo S 1997J Clin Pharmacol1997,37,2:1
4Relations of lysophosphatidylcholine in low-density lipo- protein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in pa- tients with type 2 diabetes mellitns 显示文摘Sonoki K Iwase M Sasaki N Ohdo S Hignchi S Matsuyama N 2009Diabetes Res Clin Pract2009,86,2:1
5Telmisartan and N-aeetyleys- teine suppress group V secretory phospholipase A2 expression in TNFα-stimulated human endothelial cells and reduce associated atherogenicity显示文摘Sonoki K Iwase M Ohdo S 2012J Cardiovase Pharmacol2012,60,4:1
6Chronopharmacology显示文摘Ohdo S Koyanagi S Matsunaga N 2011Nihon Yakurigaku Zasshi2011,137,3:1
7Population-Based investigation of valproic acid relative clearance using nonlinear mixed effects modeling:influence of drug-drug interaction and patient characteristics显示文摘Yukawa E To H Ohdo S 1997J Clin Pharmacol1997,37,:1
8Population-based investigation of Valproic acid relative clearance using nonlinear mixed effects modeling: influence of drug-drug interaction and patient characteristics显示文摘YUKAWA E J TO H OHDO S 1997J Clin Pharmacol1997,37,:1
9Chronotherapeutic strategy:Rhythm monitoring,manipulation and disruption显示文摘Ohdo S 2010Adv Drug Deliv Rev2010,62,:1
10Population-based investigation of valproic acid relative clearance using nonlinear mixed effects modeling: influence of drug-drug interaction and patient characteristics 显示文摘Yukawa E To H Ohdo S 1997J Clin Pharmacol1997,37,12:1
11Improving the ocular to systemic ratio of topi- cal timolol by varying the dosing time显示文摘Ohdo S Grass GM Lee VH 1999Invest Ophthalmol Vis Sci1999,32,10:1
12Population-based investigation of valproic acid relative clearance using nonlinear mixed effects modeling: influence of drug-drug interaction and patient characteristics显示文摘Yukawa E To H Ohdo S 1997J Clin Pharmacol1997,37,:1
13Chronopharmacology focused on biological clock显示文摘Ohdo S 0,,:1
14Population-based investigation of relative clearance of digoxin in Japanese patients by multiple trough screen analysis: an update显示文摘YUKAWA E HONDA T OHDO S 1997Clin Pharmacol1997,37,2:1
15Population-based investigation of valproic acid relative clearance using nonlinear mixed effects modeling: influence of drug-drug interaction and patient characteristics 显示文摘Yukawa EJ To H Ohdo S 1997J Clin Pharmacol1997,37,:1
16Changes in toxicity and effectiveness with timing of drug administration implications for drug safety显示文摘Ohdo S 2003Drug Safety2003,26,14:1
17Changes in toxicity and effectiveness with timing of drug administration implications for drug safety显示文摘 2003Drug Safety2003,26,14:1
18Chronopharmacology of antitumor effect induced by interferon-βin tumor-bearing mice显示文摘Takane H Ohdo S Yamada T Yukawa E Higuchi S 2000J Pharmacol Exp Ther2000,294,2:1
19Changes in toxicity and effectiveness with timing of drug administration implications for drug safety显示文摘Ohdo S 2003Drug Safety2003,26,14:1
20Pre-autopsy computed tomography accurately detected cerebral hemorrhage in highly decomposed bodies: Report of two cases显示文摘Ayumi Motomura Yohsuke Makino Yuriko Ohdo Go Inokuchi Daisuke Yajima Mutsumi Hayakawa Hirotaro Iwase 2013Forensic Science International . 2013 (1-3)2013,,1:1
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