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| 1 | 基于数值方法的液压蓄能器能量损失分析显示文摘根据建立的液压蓄能器数学模型,采用龙格-库塔数值方法对液压蓄能器在存储和释放能量过程中的能量损失进行了分析。分析表明,液压蓄能器的能量损失与连接管道的长度、流量的大小、连接管道横截面面积与液压蓄能器横截面面积之比有关。研究结果对液压蓄能器的设计和工程安装有参考意义。 | 刘海昌 姜继海 Okoye Celestine | 2006 | 中国机械工程2006,17,12: | 6 |
| 2 | Antimicrobial and antispasmodic activity of leaf extract and fractions of Stachytarpheta cayennensis显示文摘Objective:To investigate the antimicrobial activity of the methanol leaf extract(ME),n-hexane fraction(HF),ethylacetate fraction(EF) and methanol fraction(MF),of Stachytarpheta cayennensis C.Rich(verbenaceae) as well as to ascertain the antispasmodic effects of the ME and the various fractions(HF,EF and MF) on acetylcholine(Ach) and histamine(H) induced contractions on isolated guinea pig ileum.Methods:The in vitro agar well diffusion method was used for the antimicrobial studies while the isolated tissue method was employed for the antispasmodic test. Organisms used were all clinical isolates of Bacillus subtilis,Staphylococcus aureus,Pseudomonas aeruginosa,Salmonella paratyphi,Candida albicans and Aspergillus niger.Results:The extract and fractions exhibited dose dependent inhibition against all the bacteria tested and also exhibited insignificant antifungal activity against Candida albicans and Aspergillus niger.The minimum inhibitory concentration(MIC) of the extract and fractions(mg/mL) on Bacillus subtilis, Staphylococcus aureus,Pseudomonas aeruginosa and Salmonella paratyphi respectively were ME 5.62,14.12,22.38,2.11;EF 1.25,6.30,9.40,9.40 and MF 3.98,8.81,39.80,21.13.The n-hexane fraction exhibited MIC of 1.07 mg/mL against only Bacillus subtilis.The extract and fractions exhibited significant(P< 0.05) dose dependent attenuation of contractions induced by acetylcholine and histamine on isolated guinea pig ileum.Concentrations of the extract and fractions(μg/mL) which evoked 50%inhibition of maximal response exhibited by Ach were ME 0.64,HF 0.16,EF 0.08 and MF 0.15,while that of histamine included ME 5.12,HF 0.16,EF 0.04 and MF 0.64.Preliminary phytochemical studies on the extract and fractions indicated the presence of carbohydrates,alkaloids,saponins,flavonoids,steroids and terpenoids.Conclusions: The extract and fractions of Stachytarpheta cayennensis possessed both antibacterial and antispasmodic effects confirming the claimed use in folkloric medicine for wound healing and gastrointestinal ulceration. | Okoye TC Akah PA Okoli CO Ezike AC Mbaoji FN | 2010 | Asian Pacific Journal of Tropical Medicine2010,3,3: | 3 |
| 3 | Phytochemical analysis,hepatoprotective and antioxidant activity of Alchornea cordifolia methanol leaf extract on carbon tetrachloride-induced hepatic damage in rats显示文摘Objective:To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A.cordifolia) leaf extract.Methods:Various solvent fractions of the methanol extract of the leaf of the plant.4.cordifolia Mull.Arg(Fam:Euphorbiaceae) were evaluated for hepatoprotective activity by carbon tetrachloride-induced liver damage in rats.The degree of protection was measured by using biochemical parameters such as serum glutamate oxalate transaminase(SGOT/ AST),serum glutamate pyruvate transaminase(SCPT/ALT),alkaline phosphatase(ALP) and total bilirubin.The in vitro antioxidant activity of the extract was also evaluated by the I,I-diphenyl 2-picrylhydrazyl(DPPH) free radical scavenging assay.The extract was subjected to preliminary phytoehemical screening.Results:The ethyl acetate and chloroform fractions,at a dose of 300 mg/kg,produced significant(P<0.05) hepatoprolection by decreasing the activities of the serum enzymes and bilirubin while there were marked scavenging of the DPPH free radicals by the fractions.The effects were comparable to those of the standard drugs used for the respective experiments,silymarin and ascorbic acid.Alkaloids,flavonoids,saponins and tannins were delected in the phylochemical screening.Conclusion:From this study,it was concluded that the plant of A.cordifolia possesses hepatoprotective as well as antioxidant activities and these activities reside mainly in the ethyl acetate and acetone fractions of methanol leaf extract. | Patience O Osadebe Festus BC Okoye Philip F Uzor Nneka R Nnamani Ijeoma E Adiele Nkemakonam C Obiano | 2012 | Asian Pacific Journal of Tropical Medicine2012,5,4: | 2 |
| 4 | Short term results of pterygium surgery with adjunctive amniotic membrane graft显示文摘 | O Okoye N Oguego C Chuka Okosa M Ghanta | 2013 | Nigerian Journal of Clinical Practice2013,,3: | 2 |
| 5 | Pyloric atresia:five newcases,a new association,and a review of the literature with gui-delines显示文摘 | Okoye BO Parikh DH Buick RG | 2000 | J Pediatr Surg2000,35,8: | 1 |
| 6 | Therapeutic effect of a moderate intensity interval training program on the lipid profile in men with hypertension;a randomized controlled trial显示文摘 | Lamina S Okoye GC | 2012 | Niger J Clin Pract2012,15,: | 1 |
| 7 | Application of electromagnetic-assisted stamping (EMAS) technique in incremental sheet metal forming显示文摘 | C.N. Okoye J.H. Jiang Z.D. Hu | 2006 | International Journal of Machine Tools and Manufacture2006,,11: | 1 |
| 8 | Anticoagulant properties of bergeninfrom sacog|ottis gabonensis stem bark extract显示文摘 | Madusolumuo M A Okoye Z S C | 1995 | Med Sci Res1995,23,7: | 1 |
| 9 | Full-Potential Study of the Electronic Structure of Silver Halides显示文摘 | Okoye C M I | 2002 | Phys Stat Sol(b)2002,234,: | 1 |
| 10 | Hydrophobic treatment of corn cob by acetylation: Kinetics and thermodynamics studies显示文摘 | Nwadiogbu J O Okoye P A C Ajiwe V I | 2014 | Journal of Environmental Chemical Engineering2014,2,3: | 1 |
| 11 | Bergenin, a nigerian alcoholic bever- age additive from Sacoglottis gabonensis as an antioxidaut protector of mammalian ceils against 2,42,4-dinitrophenyl hydrazine-in- duced lipid peroxidation显示文摘 | Maduka H C C Okoye Z S C | 2006 | Int J Toxicol2006,3,1: | 1 |
| 12 | Randomised controlled trial: effects of aerobic exercise training programme on indices of adiposity and metabolic markers in hypertension显示文摘 | Lamina S1 Okoye CG Hanif SM | 2013 | J Pak Med Assoc2013,63,6: | 1 |
| 13 | The influence of Sacoglottis gabonensis stem bark extract and its isolate bergenin, nigerian alco- holic beverage additives, on the metabolic and haematological side effects of 2,4-dinitrophenyl hydrazine-induced tissue damage显示文摘 | Maduka H C C Okoye Z S C Eje A | 2002 | Vascul Pharmacol2002,39,6: | 1 |
| 14 | The impact of blood product ratios in massively transfused pediatric trauma patients显示文摘 | NOSANOV L INABA K OKOYE O | 2013 | Am J Surg2013,206,: | 1 |
| 15 | Quality of life and its eorretates in earegivers of stroke survivors from a Nigerian population显示文摘 | Akosile CO Okoye EC Nwankwo MJ | 2011 | Qual Life Res2011,20,9: | 1 |
| 16 | Effect of interval exercise training programme on C-reactive protein in the non-pharmacological management of hypertension:a randomized controlled trial显示文摘 | Lamina S Okoye GC | 2012 | Afr J Med Med Sci2012,41,4: | 1 |
| 17 | Topical steroid abuse: its use as a depigmenting agent显示文摘 | Nnoruka E Okoye O | 2006 | J Natl Med Assoc2006,98,6: | 1 |
| 18 | The antioxidant effect of Sacoglottis gabonensis stem bark extract and bergenin isolate, nigerian alco- holic beverage additives on the peroxidative deterioration of stored vegetable oils显示文摘 | Maduka H C C Okoye Z S C | 2002 | Pakistan J Biolog Sci2002,5,5: | 1 |
| 19 | Effects of interval exer- cise training programme on the indices of adiposity and bio- marker of inflammation in hypertension: a randomised con- trolled trial显示文摘 | Lamina S Okoye CG Hanif SM | 2014 | The Nigerian Postgraduate Medical Journal2014,21,2: | 1 |
| 20 | Effect of interval training programme on pulse pressure in the management of hypertension:a randomized controlled trial显示文摘 | SIKIRU L OKOYE G C | 2013 | Afr Health Sci2013,13,3: | 1 |