|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prognostic role of sensitive-to-apoptosis gene expression in rectal cancer显示文摘AIM:To investigate the association between prognosis of rectal cancer treated with chemoradiotherapy(CRT) and expression of sensitive-to-apoptosis(SAG),B-cell lymphoma-extra large(Bcl-X L) and Bcl-2 homologous antagonist/killer(Bak).METHODS:Real-time quantitative polymerase chain reaction was used to determine the expression of proteins of interest,namely SAG,Bcl-X L,Bak and β-actin,in rectal carcinoma patients who had a follow-up period of 3 years after CRT.Biopsy specimens were excised from the rectal tumor preceding CRT.RESULTS:SAG,Bcl-X L and Bak proteins showed significant correlations with each other.In multivariate analysis,patients with high vs low SAG expression showed a statistically significant difference in 2-year survival rates:56% vs 73%,respectively(P = 0.056).On the other hand,there were no significant correlations between the expression levels of all three genes and metastatic rates or tumor responses to CRT.Mean overall survival in the patients with elevated SAG expression was 27.1 mo ± 3.9 mo [95% confidence interval(CI):19.3-34.9],and in patients with reduced expression,it was 32.1 mo ± 2.5 mo(95% CI:27.3-36.9).The corresponding values for Bcl-X L were 28.0 mo ± 4.1 mo(95% CI:19.9-36.1) and 31.7 mo ± 2.9 mo(95% CI:26.0-37.5),and those for Bak were 29.8 mo ± 3.7 mo(95% CI:22.5-37.2) and 30.6 mo ± 2.4 mo(95% CI:25.5-35.0),respectively.CONCLUSION:Two-year survival rates significantly correlated with low SAG expression,and SAG may be a candidate gene for good prognosis,independent of therapeutic response of different individuals. | Sevgi A Ozden Hazan Ozyurt Zerrin Ozgen Olca Kilinc Mustafa Oncel Aylin E Gul Nimet Karadayi Nedime Serakinci Beki Kan Oya Orun | 2011 | World Journal of Gastroenterology2011，17，44： | 6 |
| 2 | Structural model calculation of antimicrobial and antifungal agents derived from clay minerals显示文摘 | OHASHI F OYA A DUCLAUX L | 1998 | Appl Clay Sci1998，12，： | 2 |
| 3 | Formation of mesopores in phenolic resin-derived carbon fiber by catalytic activation using cobalt显示文摘 | Oya A Yoshida S Alcaniz-Monge J | 1995 | Carbon1995，33，8： | 1 |
| 4 | STAT3, but not ERKs, mediates the IL-6-induced proliferation of renal cancer cells, ACHN and 769P 显示文摘 | Horiguchi A Oya M Marumo K | 2002 | Kidney Int2002，61，： | 1 |
| 5 | Antimicrobial and Antifungal Agents Derived from Clay Minerals(Ⅱ) 显示文摘 | Ohashi F Oya A | 1992 | Applied Clay Science1992，，6： | 1 |
| 6 | Changes in uterine and ovarian arterial impedance during the periovulatory period in conception and nonconception cycle显示文摘 | YOKOTA A NAKAI A OYA A et ul | 2000 | J Obstet & Gynecol Res2000，26，： | 1 |
| 7 | An antimicrobial and antifungal agent derived from montmorillonite 显示文摘 | OYA A BANSE T OHASHI F | 1991 | Applied Clay Science1991，6，2： | 1 |
| 8 | 显示文摘 | Ohashi F Oya A | 1996 | Jounary of materials science1996，31，： | 1 |
| 9 | Phenomena of catalytic graphitization显示文摘 | OYA A MARSH H | 1982 | J Mater Sci1982，17，2： | 1 |
| 10 | Dissolution kinetics of an oxidized copper ore in ammonium chloride solution显示文摘 | EKMEKYAPAR A OYA R | 2003 | Chemical and Biochemical Engineering Quarterly2003，17，4： | 1 |
| 11 | Assessment of the hepatic arterial and portal venous blood flows during pregnancy with Doppler uitrasonography显示文摘 | Nakai A Sekiya I Oya A | 2002 | Arch Gynecoi Obstet2002，266，： | 1 |
| 12 | Catalytic graphitization of carbons by various metals显示文摘 | OYA A SUGIO O | 1978 | Carbon1978，17，： | 1 |
| 13 | An antimicrobial and antifungal agent derived from montmorillonite显示文摘 | Oya A Banse F Ohashi F | 1991 | Appl Clay Sci1991，6，2： | 1 |
| 14 | Structural model calculation of antimicrobial and antifungal agents derived from clay minerals显示文摘 | OHASHI F OYA A DUCLAUX L | 1998 | Applied Clay Science1998，，12： | 1 |
| 15 | Dissolution kinetics of an oxidized copper ore in ammonium chloride solution 显示文摘 | EKMEKYAPAR A OYA R | 2003 | Chemical and Biochemical Engineering Quarterly2003，17，4： | 1 |
| 16 | 查看详情显示文摘 | Imamura R Matsui K Ozaki J Oya A | | 0，，7： | 1 |
| 17 | PDGF receptor β is a potent regulator of mesenchymal stromal cell function显示文摘 | Tokunaga A Oya T Ishii Y | | 0，，09： | 1 |
| 18 | Risk factors for peripartum blood trans- fusion in women with placenta previa:a retrospective analysis显示文摘 | Oya A Nakai A Miyake H | 2008 | J Nippon Med Sch2008，75，3： | 1 |
| 19 | Factors controlling mechanical properties of clay mineral/polypro-plene nanocomposites显示文摘 | Oya A Kurokawa Y Yasuda H | 2000 | Journal of Materials Scinece2000，35，： | 1 |
| 20 | Survivin associates with cell proliferation in renal cancer cells: regulation of Survivin expression by insulin-like growth factor-1, interferon gamma and a novel NF-kappa B inhibitor显示文摘 | Sato A Oya M Ito K | 2006 | Int J Oncol2006，28，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员