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1Prevalence of hepatitis B and C markers among refugees in Athens显示文摘AIM: To assess the prevalence of hepatitis B and C serological markers in a population of refugees living in Athens.METHODS: One hundred and thirty refugees (81 males and 49 females, mean age ±SD: 31.7±8 years) were included in the study. The hepatitis B virus surface antigen (HBsAg),the hepatitis B virus core antibody (anti-HBc) and the hepatitis C virus antibody (anti-HCV) were detected using a third-generation immunoassay.RESULTS: Twenty individuals (15.4%) were HBsAg positive and 69 (53.1%) were anti-HBc positive. The prevalence of HBsAg and anti-HBc was higher among refugees from Albania and Asia (statistical significant difference, P<0.008 and P<0.001 respectively). The prevalence of these markers was found irrelevant to age or sex. Anti-HCV was detected in the serum of 3 individuals (2.3 %). No differences among age, sex or ethnicity regarding anti-HCV prevalence were found.CONCLUSION: It can be concluded that refugees living in Athens are an immigrant population characterized by a high incidence of HBV infection. The prevalence of HBV markers is higher among refugees from Albania and Asia. It is therefore believed that the adherence to general precautions and the initiation of HBV vaccination programs will be necessary in the future, especially in these communities.Although the prevalence of HCV infection seems to be relatively low, extended epidemiological surveys are needed to provide valid results.Anastasios Roussos Constantin Goritsas Thomas Pappas Maria Spanaki Panagiota Papadaki Angeliki Ferti 2003World Journal of Gastroenterology2003,9,5:11
2Diabetes mellitus increases the prevalence of anemia in patients with chronic kidney disease:A nested case-control study显示文摘AIM: To compare anemia prevalence between matched chronic kidney disease(CKD) patients with and without diabetes mellitus(DM) and to assess factors associated with anemia development.METHODS: This is a nested case-control study of 184 type-2 diabetic and 184 non-diabetic CKD patients from a prospectively assembled database of a Nephrology outpatient clinic, matched for gender, age and estimated glomerular filtration rate(eG FR). Prevalence of anemia(hemoglobin: Men: < 13 g/dL, women: < 12 g/dL and/or use of recombinant erythropoietin) was examined in comparison, in the total population and by CKD Stage. Univariate and multivariate logistic regression analyses were conducted to identify factors associated with anemia.RESULTS: The total prevalence of anemia was higher in diabetics(47.8% vs 33.2%, P = 0.004). Accordingly, prevalence was higher in diabetics in CKD Stage 3(53.5% vs 33.1%, P < 0.001) and particularly in Stage 3a(60.4% vs 26.4%, P < 0.001), whereas it was nonsignificantly higher in Stage 4(61.3% vs 48.4%; P = 0.307). Serum ferritin was higher in diabetics in total and in CKD stages, while serum iron was similar between groups. In multivariate analyses, DM(OR = 2.206, 95%CI: 1.196-4.069), CKD Stages 3a, 3b, 4(Stage 4: OR = 12.169, 95%CI: 3.783-39.147) and serum iron(OR = 0.976, 95%CI: 0.968-0.985 per mg/d L increase) were independently associated with anemia.CONCLUSION: Prevalence of anemia progressively increases with advancing stages of CKD and is higher in diabetic than matched non-diabetic CKD patients and diabetes is independently associated with anemia occurrence. Detection and treatment of anemia in diabetic CKD patients should be performed earlier than non-diabetic counterparts.Charalampos Loutradis Alexandra Skodra Panagiotis Georgianos Panagiota Tolika Dimitris Alexandrou Afroditi Avdelidou Pantelis A Sarafdis 2016World Journal of Nephrology2016,5,4:9
3Endoscopic treatments for chronic radiation proctitis显示文摘Chronic radiation proctitis is a complication that occurs in patients who receive radiation therapy for pelvic malignancies. The common presentation is with rectal bleeding, but also rectal pain, diarrhea, tenesmus and even passage of mucus can occur. The optimal treatment of bleeding due to radiation proctitis remains unclear. Among various therapeutic options, medical management is generally ineffective and surgical intervention has a high incidence of morbidity. Promising advances have been made in endoscopic therapy, including argon plasma coagulation (APC), formalin application as well as new techniques such as radio-frequency ablation and cryoablation. APC is a safe, highly effective and long-lasting therapy in patients with rectal bleeding associated with radiation proctitis. It has been shown that several sessions of APC reduce the rate of bleeding and therefore the blood transfusion requirements. Moreover, the effect of treatment is long lasting. However, best results are achieved in patients with mild to moderate radiation proctitis, leaving space for alternative treatments for patients with more severe disease. In patients with severe or refractoryradiation proctitis intra rectal formalin application is an appropriate treatment option. Radiofrequency ablation and cryoablation have shown efficacy as alternative methods in a limited number of patients with refractory chronic radiation proctitis.George Karamanolis Panagiota Psatha Konstantinos Triantafyllou 2013World Journal of Gastrointestinal Endoscopy2013,5,7:7
4Hepatitis B virus reactivation in hepatitis B virus surface antigen negative patients receiving immunosuppression: A hidden threat显示文摘AIM: To present the characteristics and the course of a series of anti- hepatitis B virus core antibody (HBc) antibody positive patients, who experienced hepatitis B virus (HBV) reactivation after immunosuppression. METHODS: We retrospectively evaluated in our tertiary centers the medical records of hepatitis B virus surface antigen (HBsAg) negative patients who suffered from HBV reactivation after chemotherapy or immunosuppression during a 3-year period (2009-2011). Accordingly, the clinical, laboratory and virological characteristics of 10 anti-HBc (+) anti-HBs (-)/HBsAg (-) and 4 anti-HBc (+)/antiHBs (+)/HBsAg (-) patients, who developed HBV reactivation after the initiation of chemotherapy or immunosuppressive treatment were analyzed. Quantitative determination of HBV DNA during reactivation was performed in all cases by a quantitative real time polymerase chain reaction kit (COBAS Taqman HBV Test; cut-off of detection: 6 IU/mL). RESULTS: Twelve out of 14 patients were males; median age 74.5 years. In 71.4% of them the primary diagnosis was hematologic malignancy; 78.6% had received rituximab (R) as part of the immunosuppressive regimen. The median time from last chemotherapy schedule till HBV reactivation for 10 out of 11 patients who received R was 3 (range 2-17) mo. Three patients (21.4%) deteriorated, manifesting ascites and hepatic encephalopathy and 2 (14.3%) of them died due to liver failure. CONCLUSION: HBsAg-negative anti-HBc antibody positive patients can develop HBV reactivation even 2 years after stopping immunosuppression, whereas prompt antiviral treatment on diagnosis of reactivation can be lifesaving.Kalliopi Zachou Alexandros Sarantopoulos Nikolaos K Gatselis Themistoklis Vassiliadis Stella Gabeta Aggelos Stefos Asterios Saitis Panagiota Boura George N Dalekos 2013World Journal of Hepatology2013,5,7:6
5Protective and defensive roles of non-glandular trichomes against multiple stresses:structure-function coordination显示文摘As superficial structures,non-glandular trichomes,protect plant organs against multiple biotic and abiotic stresses.The protective and defensive roles of these epidermal appendages are crucial to developing organs and can be attributed to the excellent combination of suitable structural traits and chemical reinforcement in the form of phenolic compounds,primarily fl avonoids.Both the formation of trichomes and the accumulation of phenolics are interrelated at the molecular level.During the early stages of development,non-glandular trichomes show strong morphological similarities to glandular ones such as the balloon-like apical cells with numerous phenolics.At later developmental stages,and during secondary wall thickening,phenolics are transferred to the cell walls of the trichomes.Due to the diff use deposition of phenolics in the cell walls,trichomes provide protection against UV-B radiation by behaving as optical fi lters,screening out wavelengths that could damage sensitive tissues.Protection from strong visible radiation is also aff orded by increased surface light refl ectance.Moreover,the mixtures of trichome phenolics represent a superfi-cial chemical barrier that provides protection against biotic stress factors such as herbivores and pathogens.Although the cells of some trichomes die at maturity,they can modulate their quantitative and qualitative characteristics during development,depending on the prevailing conditions of the external biotic or abiotic environment.In fact,the structure and chemical constituents of trichomes may change due to the particular light regime,herbivore damage,wounding,water stress,salinity and the presence of heavy metals.Hence,trichomes represent dynamic protective structures that may greatly aff ect the outcome of many plant–environment interactions.George Karabourniotis Georgios Liakopoulos Dimosthenis Nikolopoulos Panagiota Bresta 2020Journal of Forestry Research2020,31,1:5
6Capsule endoscopy retention as a helpful tool in the management of a young patient with suspected small-bowel disease显示文摘Capsule endoscopy is an easy and painless procedure permitting visualization of the entire small-bowel during its normal peristalsis. However, important problems exist concerning capsule retention in patients at risk of small bowel obstruction. The present report describes a young patient who had recurrent episodes of overt gastrointestinal bleeding of obscure origin, 18 years after small bowel resection in infancy for ileal atresia. Capsule endoscopy was performed, resulting in capsule retention in the distal small bowel. However, this event contributed to patient management by clearly identifying the site of obstruction and can be used to guide surgical intervention, where an anastomotic ulcer is identified.Chryssostomos Kalantzis Periklis Apostolopoulos Panagiota Mavrogiannis Dimitrios Theodorou Xenophon Papaharalampous Ioannis Bramis Nikolaos Kalantzis 2007World Journal of Gastroenterology2007,13,8:5
7Common stemness regulators of embryonic and cancer stem cells显示文摘Pluripotency of embryonic stem cells(ESCs) and induced pluripotent stem cells is regulated by a well characterized gene transcription circuitry. The circuitry is assembled by ESC specific transcription factors, signal trans-ducing molecules and epigenetic regulators. Growing understanding of stem-like cells, albeit of more complex phenotypes, present in tumors(cancer stem cells), provides a common conceptual and research frame-work for basic and applied stem cell biology. In this review, we highlight current results on biomarkers, gene signatures, signaling pathways and epigenetic regulators that are common in embryonic and cancer stem cells. We discuss their role in determining the cell phenotype and finally, their potential use to design next generation biological and pharmaceutical approaches for regenerative medicine and cancer therapies.Christiana Hadjimichael Konstantina Chanoumidou Natalia Papadopoulou Panagiota Arampatzi Joseph Papamatheakis Androniki Kretsovali 2015World Journal of Stem Cells2015,7,9:4
8Long‐term administration of rifaximin improves the prognosis of patients with decompensated alcoholic cirrhosis显示文摘Jiannis Vlachogiannakos Nikos Viazis Panagiota Vasianopoulou Irene Vafiadis Dimitrios G Karamanolis Spiros D Ladas 2013J Gastroenterol Hepatol2013,,3:4
9Impact of 0.1% sodium hyaluronate and 0.2% sodium hyaluronate artificial tears on postoperative discomfort following cataract extraction surgery: a comparative study显示文摘Background:Recent artificial tear preparations have provided 0.2%concentration of sodium hyaluronate.However,no published data exist on their potential superiority against 0.1%in alleviating dry-eye-disease symptoms in cataract extraction surgery.Methods:A total of 180 patients that underwent cataract extraction surgery were randomly divided into 2 groups according to their postoperative regime:Study group(SG)received fixed combination of tobramycin and dexamethasone(FCTD)quid for 3 weeks,and additionally 0.2%sodium hyaluronate provided in the COMOD®device quid for 6 weeks.Control group(CG)received fixed combination of tobramycin and dexamethasone(FCTD)quid for 3 weeks,and additionally 0.1%sodium hyaluronate provided in the COMOD®device quid for 6 weeks.The following indexes were evaluated at 3 postoperative checkpoints:(1)Surface discomfort index(SDI)which was derived by four direct 10-scale Likert-type questions that were addressed to the patient and pertained to:(a)foreign body sensation(FBS),(b)blinking discomfort(BD),(c)stinging sensation(SS),(d)tearing sensation(TS),(2)Tear breakup time(TBUT),(3)Schirmer’s test,(4)Central corneal thickness(CCT),and (4)Central Corneal Sensitivity(CCS).Results:Both groups showed reduced CCS values at all postoperative examination points;however,SG participants had significantly better CCS(all p<0.05).SG had better TBUT than CG at the 3rd(p=0.03)and 6th examination points(p=0.04).Moreover,SG had better SDI scores at the 3rd(SDI=9.26±0.55)and 6th weeks(SDI=9.47±0.48)vs.CG participants(p=0.03 and p<0.01,respectively).Conclusion:The increased 0.2%sodium hyaluronate concentration in the artificial tears provided in the COMOD®device seems to address dry-eye-disease symptoms better in patients who underwent phacoemulsification surgery than the 0.1%concentration.Trial registration:ClinicalTrials.gov Identifier:NCT03705949 Oct 15,2018,retrospectively registered.Panagiota Ntonti Eirini-Kanella Panagiotopoulou Georgios Karastatiras Nektarios Breyannis Sevasti Tsironi Georgios Labiris 2019Eye and Vision2019,6,1:4
10Impact of polyethylene glycol 400/propylene glycol/hydroxypropyl-guar and 0.1%sodium hyaluronate on postoperative discomfort following cataract extraction surgery:a comparative study显示文摘Background:Universal postoperative guidelines for cataract extraction surgery are yet to be introduced.Artificial tears are gaining popularity as an additional integral component of the postoperative regime.The primary objective of this study was to explore the impact of two prevalent artificial tear preparations on postoperative discomfort following cataract extraction surgery.Methods:A total of 180 patients that underwent cataract extraction surgery were randomly divided into three groups according to their postoperative regime:a)Study group 1(SG1)received a fixed combination of tobramycin and dexamethasone(FCTD)quid for 3 weeks and,additionally polyethylene glycol 400/propylene glycol/hydroxypropyl-guar quid,for 6 weeks,b)Study group 2(SG2)received FCTD quid for 3 weeks and,additionally 0.1%sodium hyaluronate provided in the COMOD^(®)device quid,for 6 weeks,and,c)Control Group(CG)received only FCTD quid for 3 weeks.The following indexes were evaluated at three postoperative checkpoints:1)Subjective discomfort index(SDI)derived from four direct 10-scale Likert-type questions that were addressed to the patient and pertained to:a)foreign body sensation(FBS),b)blinking discomfort(BD),c)stinging sensation(SS),d)tearing sensation(TS),2)Tear break-up time(TBUT),3)Central corneal thickness(CCT)and,4)Central Corneal Sensitivity(CCS).Results:Both groups showed increased CCT values at the first examination point and reduced CCS values at all examination points.Furthermore,both SGs had better TBUT times at all examination points compared to CG(CG:8.86±1.08,SG1:9.59±1.45,CG2:9.45±1.33,p<0.05).BD was significantly better in both SGs only at the 1^(st) week of examination,while SDI values were better until the 3^(rd) week and only borderline better at 6^(th) week.Lastly,no significant differences were detected between SGs,regarding all parameters,at all examination points.Conclusion:Polyethylene glycol 400/propylene glycol/hydroxypropyl-guar and 0.1%sodium hyaluronate provided in the COMOD^(®)device seem to be equally efficient in alleviating OSD symptoms following cataract extraction surgery and any of them should be routinely added to the postoperative regime.Georgios Labiris Panagiota Ntonti Haris Sideroudi Vassilios Kozobolis 2017Eye and Vision2017,4,1:4
11Image-guided lens extraction surgery: a systematic review显示文摘A systematic review of the recent literature regarding the current image-guided systems used for cataract surgery or refractive lens exchange was performed based on the PubMed and Google Scholar databases in March 2018. Literature review returned 21 eligible studies. These studies compared image-guided systems with other keratometric devices regarding their accuracy, repeatability and reproducibility in measurement of keratometric values, astigmatism magnitude and axis, as well as in IOL power calculation. Additionally, the image-guided systems were compared with conventional manual ink-marking techniques for the alignment of toric IOLs. In conclusion, image-guided systems seem to be an accurate and reliable technology with measurements of high repeatability and reproducibility regarding the keratometry and IOL power calculation, but not yet interchangeable with the current established and validated keratometric devices. However, they are superior over the conventional manual inkmarking techniques for toric IOL alignment.Eirini-Kanella Panagiotopoulou Panagiota Ntonti Maria Gkika Aristeidis Konstantinidis Irfan Perente Doukas Dardabounis Konstantinos Ioannakis Georgios Labiris 2019International Journal of Ophthalmology(English edition)2019,12,1:3
12A systematic review of pseudophakic monovision for presbyopia correction显示文摘A systematic review of the recent literature regarding pseudophakic monovision as a reliable methods for presbyopia correction was performed based on the Pub Med, MEDLINE, Nature and the American Academy of Ophthalmology databases in July 2015 and data from 18 descriptive and 12 comparative studies were included in this narrative review. Pseudophakic monosvision seems to be an effective method for presbyopia with high rates of spectacles independence and minimal dysphotopsia sideeffects, that should be considered by the modern cataract surgeons.Georgios Labiris Aspa Toli Aslin Perente Panagiota Ntonti Vassilios P.Kozobolis 2017International Journal of Ophthalmology(English edition)2017,10,6:3
13Association of Helicobacter pylori infection with cardiovascular disease—Is it just a myth?显示文摘Dimitrios K. Christodoulou Haralampos J. Milionis Panagiota Pappa Konstantinos H. Katsanos Dimitrios Sigounas Matilda Florentin Moses Elisaf Epameinondas V. Tsianos 2010European Journal of Internal Medicine2010,,2:2
14Road vehicle emission factors development: A review显示文摘Vicente Franco Marina Kousoulidou Marilena Muntean Leonidas Ntziachristos Stefan Hausberger Panagiota Dilara 2013Atmospheric Environment2013,,:2
15分散体系中液滴间力学行为显示文摘分散体系的物理及化学性质依赖于分散相液滴聚并、液膜排液等微观过程,而借助于扫描探针显微镜(SPM),通过模拟分散液滴的布朗运动,可以从液滴力学行为的角度对这些现象加以研究.本文综述了SPM技术在研究可变形介质间动态作用力、变形及聚并方面的发展及现状,介绍了相关技术及在可变形介质相互作用力测量方面的应用,阐述了近年来液滴间DLVO力、非DLVO力、动水作用力等方面的研究进展,并对该方向上取得的关键成果进行了评述,在此基础上,对相关技术的发展方向及亟待开展的研究进行了展望.王玮 李楷 宫敬 ANGELI Panagiota 2015科学通报2015,60,24:2
16Lates polyamine and proline metabolismin leaves of Medicago avancat/aLa plants 显示文摘Panagiota F Chrystalla A Vasileios E The nitricoxide donor sodium nitroprusside regp 2013Free Radic Biol Med2013,56,:1
17Physicochemical study of novel organoclays as heavy metal ion adsorbents for environmental remediation显示文摘Stathi Panagiota Litina Kiriaki Gournis Dimitrios 2007Journal of colloid and interface science2007,316,2:1
18The pathogenesis of cardiac fibrosis显示文摘Ping Kong Panagiota Christia Nikolaos G. Frangogiannis 2014Cellular and Molecular Life Sciences2014,,4:1
19High throughput screening of active phar-maceutical ingredients by UPLC显示文摘MOHAMMAD A A PANAGIOTA R VINCENT A 2008Journal of Sepa- ration Science2008,31,12:1
20Engineering sensitive glutathione transferase for the detection of xenobiotics显示文摘Panagiota Kapoli Irene A. Axarli Dimitris Platis Maria Fragoulaki Mark Paine Janet Hemingway John Vontas Nikolaos E. Labrou 2008Biosensors and Bioelectronics2008,,3:1
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