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| 1 | COVID-19 pandemic:Pathophysiology and manifestations from the gastrointestinal tract显示文摘The pandemic of coronavirus disease 2019(COVID-19),caused by a newly identifiedβ-coronavirus(SARS-CoV-2)has emerged as a dire health problem,causing a massive crisis for global health.Primary method of transmission was firstly thought to be animal to human transmission.However,it has been observed that the virus is transmitted from human to human via respiratory droplets.Interestingly,SARS-CoV-2 ribonucleic acid(RNA)has been isolated from patient stools,suggesting a possible gastrointestinal(GI)involvement.Most commonly reported clinical manifestations are fever,fatigue and dry cough.Interestingly,a small percentage of patients experience GI symptoms with the most common being anorexia,diarrhea,nausea and vomiting.The presence of viral RNA in stools is also common and fecal tests can be positive even after negative respiratory samples.The exact incidence of digestive symptoms is a matter of debate.The distribution of Angiotensin converting enzyme type 2 receptors in multiple organs in the body provides a possible explanation for the digestive symptoms’mechanism.Cases with solely GI symptoms have been reported in both adults and children.Viral RNA has also been detected in stool and blood samples,indicating the possibility of liver damage,which has been reported in COVID-19 patients.The presence of chronic liver disease appears to be a risk factor for severe complications and a poorer prognosis,however data from these cases is lacking.The aim of this review is firstly,to briefly update what is known about the origin and the transmission of SARS-CoV-2,but mainly to focus on the manifestations of the GI tract and their pathophysiological background,so that physicians on the one hand,not to underestimate or disregard digestive symptoms due to the small number of patients exhibiting exclusively this symptomatology and on the other,to have SARS-CoV-2 on their mind when the“gastroenteritis”type symptoms predominate. | Michail Galanopoulos Filippos Gkeros Aris Doukatas Grigorios Karianakis Christos Pontas Nikolaos Tsoukalas Nikos Viazis Christos Liatsos Gerassimos J Mantzaris | 2020 | World Journal of Gastroenterology2020，26，31： | 7 |
| 2 | Long‐term administration of rifaximin improves the prognosis of patients with decompensated alcoholic cirrhosis显示文摘 | Jiannis Vlachogiannakos Nikos Viazis Panagiota Vasianopoulou Irene Vafiadis Dimitrios G Karamanolis Spiros D Ladas | 2013 | J Gastroenterol Hepatol2013，，3： | 4 |
| 3 | A prospective cross-over study using a sphincterotome and a guidewire to increase the success rate of common bile duct cannulation显示文摘AIM: During endoscopic retrograde cholangiopancreatography (ERCP), selective cannulation of the common bile duct (CBD) is required in most of the cases.METHODS: From June 2001 till December 2002, all patients referred to our unit for ERCP were considered for entry into the study. Selective CBD cannulation was first attempted with a standard catheter with or without the use of a guidewire. In cases, where CBD cannulation was considered unsuccessful, patients were crossed over to a double-lumen sphincterotome and a guidewire. All patients were hospitalized for 24 h after the procedure in order to assess the incidence of post-ERCP complications.RESULTS: The study sample consisted of 158 patients.Selective CBD cannulation using a standard ERCP catheter with or without the assistance of a guidewire, was accomplished in 129 patients (success rate: 81.65%).From the 29 patients who were crossed over to a sphincterotome and a guidewire, selective CBD cannulation was achieved in 24; the overall success rate rising to 96.8%. Meanwhile, the use of this technique did not increase the incidence of post-ERCP complications.CONCLUSION: The use of a sphincterotome and a guidewire increases the success rate of selective bile duct cannulation in cases that this has not been accomplished with a standard catheter. | Georgios Karamanolis Aikaterini Katsikani Nikos Viazis Gerasimos Stefanidis Spilios Manolakopoulos Spiros Sgouros Efthimia Papadopoulou Apostolos Mantides | 2005 | World Journal of Gastroenterology2005，11，11： | 3 |
| 4 | Colon capsule endoscopy is feasible to perform after incomplete colonoscopy and guides further workup in clinical practice显示文摘 | Konstantinos Triantafyllou Nikos Viazis Panagiotis Tsibouris Georgios Zacharakis Chryssostomos Kalantzis Demetrios G. Karamanolis Spiros D. Ladas | 2014 | Gastrointestinal Endoscopy2014，，2： | 3 |
| 5 | 消化性溃疡出血患者使用生长抑素抑制胃酸分泌效果优于潘托拉唑:一项前瞻性、随机、安慰剂对照试验 | Avgerinos A. Sgouros S. Viazis N. 陈云茹 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，9： | 2 |
| 6 | Is there a role for second-look capsule endoscopy in patients with obscure GI bleeding after a nondiagnostic first test?显示文摘 | Nikos Viazis Kostis Papaxoinis John Vlachogiannakos Alkiviadis Efthymiou Ioannis Theodoropoulos Dimitrios G. Karamanolis | 2009 | Gastrointestinal Endoscopy2009，，4： | 2 |
| 7 | A comparative audy of postendoscopic sphincterotomy complications with various types of electrosurgical current in patients with choledocholithiasis显示文摘 | Karamanolis G Viazis N | 2003 | Gastrointest Endosc2003，57，： | 1 |
| 8 | Somatostatin inhibits gastric acid secretion more effectively than pantoprazole in patients with peptic ulcer bleeding: a prospective, randomized, placebo - controlled trial 显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Stand J Gastroenterol JT Scandinavian journal of gastroenterology2005，40，51： | 1 |
| 9 | Efficient orthodontic treatment timing显示文摘 | Viazis AD | | 0，，5： | 1 |
| 10 | Somatostatin inhibits gastri- eaeid secretion more effectively than pantoprazole in patients with peptic ulcer bleeding: a prospective, randomized, placebo-controlled trial显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Seand J Gastroentero12005，40，5： | 1 |
| 11 | Somatostatin inhibits gastric acid secretion more effectively than pantoprazole in patients with peptic ulcer bleeding :a prospective,randomized,placebo-controlled trial显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Scand J Gastroenterol2005，40，5： | 1 |
| 12 | Somatostatin inhibits gastric acid secretion more effectively than pantoprazole in patients with pepticulcer bleeding:a prospective,randomized,placebo-controlled trial显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Scand J Gastroenterol2005，40，5： | 1 |
| 13 | Somatostatin inhibits gas- tric acid secretion more effectively than pantoprazole in patients with peptic ulcer bleeding:a prospective,randomized,placebo- controlled trial显示文摘 | Avgerinors A Sgouros S Viazis N | 2005 | Scand J Gastroenterol2005，40，： | 1 |
| 14 | Selective serotoninreuptake inhibitors for the treatment of hypersensitive esophagus : arandomized, double-blind, placebo-controlled study 显示文摘 | Viazis N Keyoglou A Kanellopoulos AK | 2012 | Am J Gas-troenterol2012，，： | 1 |
| 15 | Somatostatin inhibits gastric acid secretion more effectively than pantoprazole in patients with peptic ulcer bleeding: a prospective, randomized, placebo-controlled trial显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Scand J Gastroenterol2005，40，： | 1 |
| 16 | P447 Long term benefit of one year infliximab administration for the treatment of chronic refractory pouchitis显示文摘 | N. Viazis M. Giakoumis J. Anastasiou K. Katopodi G. Kechagias G. Tribonias D. Karamanolis | 2013 | Journal of Crohn’s and Colitis2013，，： | 1 |
| 17 | Somatostatin inhibits gas- tric acid secretion more effectively than pantoprazole in patients with peptic ulcer bleeding: a prospective, randomized, placebo - con- trolled trial 显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Scand J Gastroenterol2005，40，5： | 1 |
| 18 | Bowel preparation increases the diagnostic yield of capsule endoscopy:a prospective,randomized,controlled study显示文摘 | Viazis N Sgouros S Papaxoinis K | 2004 | Gastrointest Endosc2004，60，4： | 1 |
| 19 | Somato statin inhibits gastr acids ecretion more effectively than pantnprazole in patients with peptic ulcer bleeding: a prospective, randomized, placebo - controlled trial显示文摘 | Avgerinos A Sgouros S Viazis N | 2005 | Scand J Gastroenterol2005，40，5： | 1 |
| 20 | mechanical lithotripsy for the management of large bile duct stones: a prospective randomized study 显示文摘 | Stefanidis G Viazis N Pleskow D et aL Large balloon dilation vs | 2011 | Am J Gastroenterol2011，106，2： | 1 |
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