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7篇 您的检索式:作者名="Parakrama"
    题名 作者 年代 出处 被引量
1Proposed approach to the challenging management of progressive gastroesophageal reflux disease显示文摘The progression of gastroesophageal reflux disease(GERD) in patients who are taking proton pump inhibitors(PPIs) has been reported by several investigators,leading to concerns that PPI therapy does not address all aspects of the disease.Patients who are at risk of progression need to be identified early in the course of their disease in order to receive preventive treatment.A review of the literature on GERD progression to Barrett's esophagus and the associated physiological and pathological changes was performed and risk factors for progression were identified.In addition,a potential approach to the prevention of progression is discussed.Current evidence shows that GERD can progress;however,patients at risk of progression may not be identified early enough for it to be prevented.Biopsies of the squamocolumnar junction that show microscopic intestinalization of metaplastic cardiac mucosa in endoscopically normal patients are predictive of future visible Barrett's esophagus,and an indicator of GERD progression.Such changes can be identified only through biopsy,which is not currently recommended for endoscopically normal patients.GERD treatment should aim to prevent progression.We propose that endoscopically normal patients who partially respond or do not respond to PPI therapy undergo routine biopsies at the squamocolumnar junction to identify histological changes that may predict future progression.This will allow earlier intervention,aimed at preventing Barrett's esophagus.Joachim Labenz Parakrama T Chandrasoma Laura J Knapp Tom R DeMeester 2018World Journal of Gastrointestinal Endoscopy2018,10,9:7
2Prevalence ofCampylobacter pylori and association with antral mucosal histology in subjects with and without upper gastrointestinal symptoms显示文摘Cynthia W. Pettross MD Maria D. Appleman PhD Hartley Cohen MD Jorge E. Valenzuela MD Parakrama Chandrasoma MD Loren A. Laine MD 1988Digestive Diseases and Sciences1988,,6:1
3Association of Adenocarcinomas of the Distal Esophagus, “Gastroesophageal Junction,” and “Gastric Cardia” With Gastric Pathology显示文摘Sulochana Wijetunge Yanling Ma Steve DeMeester Jeffrey Hagen Tom DeMeester Parakrama Chandrasoma 2010The American Journal of Surgical Pathology2010,,10:1
4The Histologic Squamo-oxyntic Gap: An Accurate and Reproducible Diagnostic Marker of Gastroesophageal Reflux Disease显示文摘Parakrama Chandrasoma Sulochana Wijetunge Steven R. DeMeester Jeffrey Hagen Tom R. DeMeester 2010The American Journal of Surgical Pathology2010,,11:1
5Definition of Histopathologic Changes in Gastroesophageal Reflux Disease显示文摘Parakrama T. Chandrasoma Dilani M. Lokuhetty Tom R. Demeester Cedric G. Bremner Jeffrey H. Peters Stefan Oberg Susan Groshen 2000The American Journal of Surgical Pathology2000,,3:1
6Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score显示文摘Wael N. Yacoub Mikael Petrosyan Indu Sehgal Yanling Ma Parakrama Chandrasoma Rodney J. Mason Davide Festi 2010Gastroenterology Research and Practice2010,,:1
7Improving batch chemical process 显示文摘 1985Chem Eng1985,9,:1
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