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153篇 您的检索式:作者名="Parks GA"
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1Apoptotic signaling through reactive oxygen species in cancer cells显示文摘Reactive oxygen species(ROS) take part in diverse biological processes like cell growth,programmed cell death,cell senescence,and maintenance of the transformed state through regulation of signal transduction. Cancer cells adapt to new higher ROS circumstance. Sometimes,ROS induce cancer cell proliferation. Meanwhile,elevated ROS render cancer cells vulnerable to oxidative stress-induced cell death. However,this prominent character of cancer cells allows acquiring a resistance to oxidative stress conditions relative to normal cells. Activated signaling pathways that increase the level of intracellular ROS in cancer cells not only render up-regulation of several genes involved in cellular proliferation and evasion of apoptosis but also cause cancer cells and cancer stem cells to develop a high metabolic rate. In over the past several decades,many studies have indicated that ROS play a critical role as the secondary messenger of tumorigenesis and metastasis in cancer from both in vitro and in vivo. Here we summarize the role of ROS and anti-oxidants in contributing to or preventing cancer. In addition,we review the activated signaling pathways that make cancer cells susceptible to death.Daejin Kim Ga Bin Park Dae Young Hur 2014World Journal of Immunology2014,4,3:2
2Comparison of closed - suction drainage and no drainage after primary total knee arthroplasty显示文摘Holt BT Parks NL Engh GA 1997Orthopedics1997,20,12:1
3The vascular endothelial growth factor(VEGF)isoforms:differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrixbound VEGF显示文摘Park JE Keller GA Ferrara N 1993Mol Biol Med1993,4,1:1
4Comparison of closed-suction drainage and no drainage after primary total knee arthroplasty 显示文摘Holt BT Parks NL Engla GA 1997Orthopedics1997,20,12:1
5Chronic cerebrovascular insuriciency induces dementia-like deficits inaged rats显示文摘De la Torre JC Fortin T Park GA 1992Brain Res1992,582,2:1
6Chronic cerebrovascular insufficiency induces dementia-like deficit in age rats显示文摘de la Torre JC Fortin T Park GA 1992Brain Res1992,582,2:1
7Chronic cerebrovascular in sufficiency induces dementia--like deficits in aged rats显示文摘De Ia Torre JC Fortin T Park GA 1992Brain Res1992,582,2:1
8Lipid profile changes during the first year after kidney transplantation:risk factors and influence of the immunosuppressive drug regimen显示文摘Spinelli GA Felipe CR Park SI 2011Transplant Proc2011,43,10:1
9The Isoelectric points of solid oxides , solid hydroxides and aqueous hydroxo complex systems显示文摘PARKS GA 1995ChemRev1995,65,:1
10The vascular endothelial growth factor isoforms:differentisl depsoition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF 显示文摘Park J Keller GA Ferrara N 1993Mol Biol Cell1993,4,:1
11The vascular endothelial growth factor (VEGF)isoforms:differential deposition into the subeplthellal extracellular matrix and bioactivity Of extracellular main-bound VEGF显示文摘Park JF Keller GA Ferrara N 1993Mol Biol Cell1993,4,12:1
12The zero point of charge of oxides显示文摘Parks GA De Bruyn PL 1962The Journal of Physical Chemistry1962,66,:1
13Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing显示文摘Rodrigues GA Naujokas MA Park M 1991Mol Cell Biol1991,11,:1
14Chronic cerebrovaseular insufficiency induces dementia-like deficits in aged rats显示文摘de la Torte JC Fortin T Park GA 1992Brain Res1992,582,2:1
15Prevalence in the UnitedStates of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme显示文摘Park CH Robicsek A Jacoby GA 2006Antimicrob Agents Chemother2006,50,11:1
16Modulation of humoral and cell- mediated immune responses by dietary lutein in cats 显示文摘Kim HW Chew BP Wong TS Park JS Weng BB Byrne KM Hayek MG Reinhart GA 2000Vet Immunol Immunopathol2000,15,73:1
17cloning and expression analysis of pregnancy-associated glycoproteins expressed in trophoblasts of the white-tail deer placenta显示文摘Brandt GA Parks TE Killian GA 2007Mol Reprod Dev2007,74,11:1
18The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepi- thelial extracellular matrix and bioactivity of extracellular matrix - bound VEGF 显示文摘Park JE Keller GA Ferrara N 1993Mol Biol Cell1993,4,12:1
19Chronic cerebrovascular insufficiency induces dementia-like deficits in aged rats 显示文摘Torre JC Fortin T Park GA 1992Brain Res1992,582,2:1
20The vascular endothelial growth factor(VEGF)is of forms: differential deposition into the subeithelial extracelluar matrix and bioactivity of extracelluar maxtrix-bound VEGF显示文摘Park J Keller GA Ferrara N 1993Mol Biol Cell1993,4,:1
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