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| 1 | Assessing the USLE Crop and Management Factor C for Soil Erosion Modeling in a Large Mountainous Watershed in Central China显示文摘Due to the impoundment of the Yangtze River, the Three Gorges Dam in China fosters high land-use dynamics. Soil erosion is expected to increase dramatically. One of the key factors in soil erosion control is the vegetation cover and crop type. However, determining these factors adequately for the use in soil erosion modeling is very time-consuming especially for large mountainous areas, such as the Xiangxi (香溪) catchment in the Three Gorges area. In our study, the crop and management factor C was calculated using the fractional vegetation cover (CFVC) based on Landsat-TM images from 2005, 2006, and 2007 and on literature studies (CLIT). In 2007, the values of CFVC range between 0.001 and 0.98 in the Xiangxi catchment. The mean CFVC value is 0.05. CLIT values are distinctly higher, ranging from 0.08 to 0.46 with a mean value of 0.32 in the Xiangxi catchment. The mean potential soil loss amounts to 120.62 t/ha/a in the Xiangxi catchment when using CLIT for modeling. Based on CFVC, the predicted mean soil loss in the Xiangxi catchment is 11.50 t/ha/a. Therefore, CLIT appears to be more reliable than the C factor based on the fractional vegetation cover. | Sarah Schnbrodt Patrick Saumer Thorsten Behrens Christoph Seeber Thomas Scholten | 2010 | Journal of Earth Science2010，21，6： | 12 |
| 2 | 诊断性试验和策略的证据质量和推荐强度的分级显示文摘GRADE系统能对诊断性试验或策略的证据质量和推荐强度进行分级。本文旨在阐释在此过程中如何考虑患者的重要结局, | Holger J Schünemann Andrew D Oxman Jan Brozek Paul Glasziou Roman Jaeschke Gunn E Vist John W Williams Jr Regina Kunz Jonathan Craig Victor M Montori Patrick Bossuyt Gordon H Guyatt 李晓 黄程 陈耀龙 李幼平 | 2009 | 中国循证医学杂志2009，9，5： | 7 |
| 3 | Cabozantinib in Progressive Medullary Thyroid Cancer显示文摘 | Rossella Elisei Martin J. Schlumberger Stefan P. Müller Patrick Sch?ffski Marcia S. Brose Manisha H. Shah Lisa Licitra Barbara Jarzab Viktor Medvedev Michael C. Kreissl Bruno Niederle Ezra E.W. Cohen Lori J. Wirth Haythem Ali Colin Hessel Yifah Yaron Doug | 2013 | Journal of Clinical Oncology2013，，29： | 3 |
| 4 | Mental illness stigma: Concepts, consequences, and initiatives to reduce stigma显示文摘 | Nicolas Rüsch Matthias C. Angermeyer Patrick W. Corrigan | 2005 | European Psychiatry2005，，8： | 1 |
| 5 | Easily applicable multiple testing procedures to improve the interpretation of clinical trials with composite endpoints显示文摘 | Svenja Schüler Annegret Mucha Patrick Doherty Meinhard Kieser Geraldine Rauch | 2014 | International Journal of Cardiology2014，，： | 1 |
| 6 | Corticosteroid resistance in sepsis is influenced by microRNA-124–induced downregulation of glucocorticoid receptor-α*显示文摘 | Carola Ledderose Patrick M?hnle Elisabeth Limbeck Stefanie Schütz Florian Weis Jessica Rink Josef Briegel Simone Kreth | 2012 | Critical Care Medicine2012，，10： | 1 |
| 7 | Intestinal Wnt in the transition from physiology to oncology显示文摘Adult stem cells are necessary for self-renewal tissues and regeneration after damage.Especially in the intestine,which self-renews every few days,they play a key role in tissue homeostasis.Therefore,complex regulatory mechanisms are needed to prevent hyperproliferation,which can lead in the worst case to carcinogenesis or under-activation of stem cells,which can result in dysfunctional epithelial.One main regulatory signaling pathway is the Wnt/β-catenin signaling pathway.It is a highly conserved pathway,withβ-catenin,a transcription factor,as target protein.Translocation ofβ-catenin from cytoplasm to nucleus activates the transcription of numerous genes involved in regulating stem cell pluripotency,proliferation,cell differentiation and regulation of cell death.This review presents a brief overview of the Wnt/β-catenin signaling pathway,the regulatory mechanism of this pathway and its role in intestinal homeostasis.Additionally,this review highlights the molecular mechanisms and the histomorphological features of Wnt hyperactivation.Furthermore,the central role of the Wnt signaling pathway in intestinal carcinogenesis as well as its clinical relevance in colorectal carcinoma are discussed. | Julia Swoboda Patrick Mittelsdorf Yuan Chen Ralf Weiskirchen Johannes Stallhofer Silke Schüle Nikolaus Gassler | 2022 | World Journal of Clinical Oncology2022，13，3： | 1 |
| 8 | Fusion and metabolism of plant cells as affected by microgravity显示文摘 | Rüdiger Hampp Ellen Hoffmann Kristina Sch?nherr Patrick Johann Luigi De Filippis | 1997 | Planta1997，，1： | 1 |
| 9 | Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes显示文摘 | Patrick Sch?ffski Isabelle Laure Ray-Coquard Angela Cioffi Nguyen Bin Bui Sebastian Bauer Joerg Thomas Hartmann Anders Krarup-Hansen Viktor Grünwald Raf Sciot Herlinde Dumez Jean-Yves Blay Axel Le Cesne Jantien Wanders Carolyn Hayward Sandrine Marreaud Mo | 2011 | Lancet Oncology2011，，11： | 1 |
| 10 | 混凝土路面砖通过“应力测试”显示文摘高浓度除冰剂.甚至在没有冰冻作用情况下.所带来的碱土金属氯化物也会对混凝土产生持续性损伤。位于德国杜塞尔多夫市的水泥工业研究院,针对各种类型除冰剂对混凝土路面砖的影响进行了研究,实验室试验结果表明:具有足够的水泥含量和低水灰比的混凝土路面砖,显示出很好的抗冻性能和抗除冰剂侵蚀的能力。高浓度碱土金属氯化物溶液对混凝土路面砖没有产生明显的损坏。 | Patrick Schffel Sebastian Palm Dietmar Ulonska 崔玉忠 | 2014 | 建筑砌块与砌块建筑2014，，3： | 0 |
| 11 | Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease显示文摘Over 2 billion people worldwide are estimated to have nonalcoholic fatty liver disease(NAFLD),defined by excess hepatic fat.Commonly,progression into nonalcoholic steatohepatitis(NASH)is characterized by the onset of liver inflammation following exacerbated steatosis.1 This suggests that reducing liver inflammation(e.g.through lifestyle interventions involving exercise training)may come secondary to a reduction of steatosis.However,both the metabolic and inflammatory processes involved in NAFLD are under circadian control and could respond differently to exercise at different times of day.2 To investigate the time-of-day–dependent effect of exercise training on NAFLD amelioration in the early disease stages we trained high-fat high-cholesterol(HFHC)-fed APOE*3-Leiden cholesteryl ester transfer protein(CETP)mice during their early or late active period.This mouse model was chosen because of its humanized lipid metabolism and its ability to develop all hallmarks of human NAFLD upon HFHC feeding. | Artemiy Kovynev Zhixiong Ying Joost M.Lambooij Hendrik J.P.van der Zande Bruno Guigas Patrick C.N.Rensen Milena Schönke | 2023 | Journal of Clinical and Translational Hepatology2023，11，5： | 0 |
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