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| 1 | Ethnic differences in inflammatory bowel disease: Results from the United Kingdom inception cohort epidemiology study显示文摘BACKGROUND The current epidemiology of inflammatory bowel disease(IBD)in the multiethnic United Kingdom is unknown.The last incidence study in the United Kingdom was carried out over 20 years ago.AIM To describe the incidence and phenotype of IBD and distribution within ethnic groups.METHODS Adult patients(>16 years)with newly diagnosed IBD(fulfilling Copenhagen diagnostic criteria)were prospectively recruited over one year in 5 urban catchment areas with high South Asian population.Patient demographics,ethnic codes,disease phenotype(Montreal classification),disease activity and treatment within 3 months of diagnosis were recorded onto the Epicom database.RESULTS Across a population of 2271406 adults,339 adult patients were diagnosed with IBD over one year:218 with ulcerative colitis(UC,64.3%),115 with Crohn's disease(CD,33.9%)and 6 with IBD unclassified(1.8%).The crude incidence of IBD,UC and CD was 17.0/100000,11.3/100000 and 5.3/100000 respectively.The age adjusted incidence of IBD and UC were significantly higher in the Indian group(25.2/100000 and 20.5/100000)compared to White European(14.9/100000,P=0.009 and 8.2/100000,P<0.001)and Pakistani groups(14.9/100000,P=0.001 and 11.2/100000,P=0.007).The Indian group were significantly more likely to have extensive disease than White Europeans(52.7%vs 41.7%,P=0.031).There was no significant difference in time to diagnosis,disease activity and treatment.CONCLUSION This is the only prospective study to report the incidence of IBD in an ethnically diverse United Kingdom population.The Indian ethnic group showed the highest age-adjusted incidence of UC(20.5/100000).Further studies on dietary,microbial and metabolic factors that might explain these findings in UC are underway. | Ravi Misra Jimmy Limdi Rachel Cooney Samia Sakuma Matthew Brookes Edward Fogden Sanjeev Pattni Naveen Sharma Tariq Iqbal Pia Munkholm Johan Burisch Naila Arebi | 2019 | World Journal of Gastroenterology2019，25，40： | 1 |
| 2 | Fibroblast growth factor 19 in patients with bile acid diarrhoea: a prospective comparison of FGF 19 serum assay and SeHCAT retention显示文摘 | S. S. Pattni W. G. Brydon T. Dew I. M. Johnston J. D. Nolan M. Srinivas P. Basumani K. D. Bardhan J. R. F. Walters | 2013 | Aliment Pharmacol Ther2013，，8： | 1 |
| 3 | New insights into bile acid malab-sorption显示文摘 | Johnston I Nolan J Pattni S et a1 | 2011 | Current Gastroenterology Report2011，13，5： | 1 |
| 4 | Diarrhea in crohn's dis- ease:investigating the role of the ileal hormone Fibroblast Growth Factor 19显示文摘 | Nolan J D Johnston I M Pattni S S | 2014 | Crohns Colitis2014，10，： | 1 |
| 5 | 何方好汉?ST轿跑版是也!显示文摘好想要一辆杀气腾腾的斯巴鲁BRZSTI吗?这里刚好有一辆,不过有一个小小问题——此乃一次性的概念作,最少暂时来说是这样。 | Vijay Pattni Tony | 2015 | 汽车测试报告2015，0，6： | 0 |
| 6 | 2002:回溯风云显示文摘正当自动驾驶汽车越来越接近现实,宝马却偏偏另觅途径,为祖传衣钵和现代物料牵红线。 | VIJAY PATTNI | 2016 | 汽车测试报告2016，0，10： | 0 |
| 7 | AMG GT GT3显示文摘“我觉得有点热。”这位沉着的德国人轻声说道。真可怜呀,他刚刚才熬过连续五小时炙烤全身感官的酷刑,不单被牢牢绑在通风不足的驾驶舱中,还要在牵引力控制系统缺席的情况下施展浑身解数攻下西班牙东北部某条紧凑无情的赛道, | VIJAY PATTNI ANDREAS LINDLAHR TONY | 2015 | 汽车测试报告2015，0，6： | 0 |
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