|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A comparison of methods for sketch-based 3D shape retrieval显示文摘 | Bo Li Yijuan Lu Afzal Godil Tobias Schreck Benjamin Bustos Alfredo Ferreira Takahiko Furuya Manuel J. Fonseca Henry Johan Takahiro Matsuda Ryutarou Ohbuchi Pedro B. Pascoal Jose M. Saavedra | 2014 | Computer Vision and Image Understanding2014，，： | 2 |
| 2 | Gastrin attenuates sepsis-induced myocardial dysfunction by down-regulation of TLR4 expression in macrophages显示文摘Myocardial dysfunction is the most serious complication of sepsis.Sepsis-induced myocardial dysfunction(SMD)is often associated with gastrointestinal dysfunction,but its pathophysiological significance remains unclear.The present study found that patients with SMD had higher plasma gastrin concentrations than those without SMD.In mice,knockdown of the gastrin receptor,cholecystokinin B receptor(Cckbr),aggravated lipopolysaccharide(LPS)-induced cardiac dysfunction and increased inflammation in the heart,whereas the intravenous administration of gastrin ameliorated SMD and cardiac injury.Macrophage infiltration plays a significant role in SMD because depletion of macrophages by the intravenous injection of clodronate liposomes,48 h prior to LPS administration,alleviated LPSinduced cardiac injury in Cckbr-deficient mice.The intravenous injection of bone marrow macrophages(BMMs)overexpressing Cckbr reduced LPS-induced myocardial dysfunction.Furthermore,gastrin treatment inhibited toll-like receptor 4(TLR4)expression through the peroxisome proliferator-activated receptor a(PPAR-a)signaling pathway in BMMs.Thus,our findings provide insights into the mechanism of the protective role of gastrin/CCKBR in SMD,which could be used to develop new treatment modalities for SMD. | Dandong Fang Yu Li Bo He Daqian Gu Mingming Zhang Jingwen Guo Hongmei Ren Xinyue Li Ziyue Zhang Ming Tang Xingbing Li Donghai Yang Chunmei Xu Yijie Hu Hongyong Wang Pedro AJose Yu Han Chunyu Zeng | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 1 |
| 3 | Global physical activity levels: surveillance progress, pitfalls, and prospects显示文摘 | Pedro C Hallal Lars Bo Andersen Fiona C Bull Regina Guthold William Haskell Ulf Ekelund | 2012 | The Lancet2012，，9838： | 1 |
| 4 | Optimization of char and tar conversion in fluidized bed biomass gasifiers显示文摘 | Alberto Gómez-Barea Pedro Ollero Bo Leckner | 2013 | Fuel2013，，： | 1 |
| 5 | Both interleukin-3andinterleukin-6 are necessary for better Ex vivo expansion of CD133+cells from umbilical cord blood显示文摘 | Pedro BO Lu AL Fernando FE | 2010 | Stem Cells Dev2010，19，3： | 1 |
| 6 | A Numerical Study on Hydraulic Fracturing Problems via the Proper Generalized Decomposition Method显示文摘The hydraulic fracturing is a nonlinear,fluid-solid coupling and transient problem,in most cases it is always time-consuming to simulate this process numerically.In recent years,although many numerical methods were proposed to settle this problem,most of them still require a large amount of computer resources.Thus it is a high demand to develop more efficient numerical approaches to achieve the real-time monitoring of the fracture geometry during the hydraulic fracturing treatment.In this study,a reduced order modeling technique namely Proper Generalized Decomposition(PGD),is applied to accelerate the simulations of the transient,non-linear coupled system of hydraulic fracturing problem,to match this extremely tight response time constraint.The separability of the solution in space and time dimensions is studied for a simplified model problem.The solid and fluid equations are coupled explicitly by inverting the solid discrete problem,and a simple iterative procedure to handle the non-linear characteristic of the hydraulic fracturing problem is proposed in this work.Numeral validation illustrates that the results of PGD match well with these of standard finite element method in terms o f fracture opening and fluid pressure in the hydro-fracture.Moreover,after the off-line calculations,the numerical results can be obtained in real time. | Daobing Wang Sergio Zlotnik Pedro Díez Hongkui Ge Fujian Zhou Bo Yu | 2020 | Computer Modeling in Engineering & Sciences2020，，2： | 1 |
| 7 | Maternal serum adiponectin multimers in gestational diabetes显示文摘 | Shali Mazaki-Tovi Roberto Romero Edi Vaisbuch Offer Erez Pooja Mittal Tinnakorn Chaiworapongsa Sun Kwon Kim Percy Pacora Lami Yeo Francesca Gotsch Zhong Dong Bo Hyun Yoon Sonia S. Hassan Juan Pedro Kusanovic | 2009 | Journal of Perinatal Medicine2009，，6： | 1 |
| 8 | Alginate modifies the physiological impact of CeO2nanoparticles in corn seedlings cultivated in soil显示文摘Alginates are naturally occurring components of organic matter in natural soil whose effects on nanoparticle(NP) toxicity to plants is not well understood. In the present study, corn plants were grown for one month in soil spiked with 400 mg/kg CeO2NPs with various alginate concentrations. After one month of growth in the NPs impacted soil, plants were harvested and analyzed for Ce and mineral element concentrations. Chlorophyll concentration and heat shock protein 70, used as biomarkers for oxidative stress, were also evaluated. Results showed that, compared to CeO2 NPs treatment, alginate at 10, 50, and 100 mg/kg increased Ce concentration in roots by approximately 46%, 38%, and 29% and by 115%, 45%, and 56% in shoots, respectively. CeO 2 NPs without alginate increased Mn accumulation in roots by 34% compared to control. CeO2 NPs with low and medium alginate increased Mn by ca. 92% respect to NPs without alginate and by ca. 155% respect to control. CeO2 NPs without/with alginate significantly increased accumulation of Fe and Al in roots. In addition, alginate at 50 mg/kg increased Zn accumulation in roots by 52% compared to control. In shoots, K increased at all NP treatments but the accumulation of other elements was not affected. Alginate enlarged the impact of CeO2 NPs to corn plants by reducing chlorophyll a content and triggering overexpression of heat shock protein 70. | Lijuan Zhao Jose R.Peralta-Videa Bo Peng Susmita Bandyopadhyay Baltazar Corral-Diaz Pedro Osuna-Avila Milka O.Montes Arturo A.Keller Jorge L.Gardea-Torresdey | 2014 | Journal of Environmental Sciences2014，26，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员