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1Correlation between expression of gastrin, somatostatin and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma显示文摘AIM: To explore the correlation between expression of somatostatin (SS), gastrin (GAS) and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma.METHODS: Sixty-two large intestine cancer tissue samples were randomly and retrospectively selected from patients with large intestine carcinoma. Immunohistochemical staining for bcl-2, bax, GAS, SS was performed according to the standard streptavidin-biotin-peroxidase (S-P) method.According to the semi-quantitative integral evaluation, SS and GAS were divided into three groups as follows. Scores1-3 were defined as the low expression group, 4-8 as the intermediate expression group, 9-16 as the high expression group. Bax and bcl-2 protein expressions in different GAS and SS expression groups of large intestine carcinoma were assessed.RESULTS: The positive expression rate of bax had a prominent difference between SS and GAS high, intermediate and low expression groups (P<0.05, x2ss = 9.246; P<0.05,x2GAS = 6.981). The positive expression rate of bax in SS high (80.0%, 8/10) and intermediate (76.5%, 13/17)expression groups was higher than that in low expression group (40.0%, 14/35) (P<0.05, x2high vs low = 5.242; P<0.05,x2middle vs low = 6.097). The positive expression rate of bax in GAS high expression group (27.3%, 3/8) was lower than that in low expression group (69.4%, 25/36) (P<0.05,x2 = 4.594). However, bax expression in GAS intermediate expression group (46.7%, 7/15) was lower than that in low expression group, but not statistically significant. The positive expression rate of bcl-2 had a prominent difference between SS and GAS high, intermediate and low expression groups (P<0.05, x2ss = 7.178; P<0.05, x2GAS = 13.831). The positive expression rate of bcl-2 in GAS high (90.9%, 10/11)and intermediate (86.7%, 13/15) expression groups was higher than that in low expression group (44.4%, 16/36)(P<0.05,x2high vs low = 5.600; P<0.05, x2 middle vs low = 7.695).However, the positive expression rate of bcl-2 in SS high (40.0%, 4/10) and intermediate (47.1%, 8/9) expression groups was lower than that in low expression group (77.1%, 27/35)(P<0.05, x2 high vs low = 4.710; P<0.05, x2 middle vs low = 4.706).There was a significant positive correlation between the integral ratio of GAS to SS and the integral of bcl-2 (P<0.01,r=0.340). However, there was a negative correlation between the integral ratio of GAS to the SS and bax the integral of (P<0.05, r = -0.299).CONCLUSION: The regulation and control of gastrin,somatostatin in cell apoptosis of large intestine carcinoma may be directly related to the abnormal expression of bcl-2, bax.Jia-DingMao PeiWu Xiang-HouXia Ji-QunHu Wen-BinHuang Guo-QiangXu 2005World Journal of Gastroenterology2005,11,5:27
2A land use regression model incorporating data on industrial point source pollution显示文摘Advancing the understanding of the spatial aspects of air pollution in the city regional environment is an area where improved methods can be of great benefit to exposure assessment and policy support. We created land use regression (LUR) models for SO2, NO2 and PM10 for Tianjin, China. Traffic volumes, road networks, land use data, population density, meteorological conditions, physical conditions and satellite-derived greenness, brightness and wetness were used for predicting SO2, NO2 and PM10 concentrations. We incorporated data on industrial point sources to improve LUR model performance. In order to consider the impact of different sources, we calculated the PSIndex, LSIndex and area of different land use types (agricultural land, industrial land, commercial land, residential land, green space and water area) within different buffer radii (1 to 20 km). This method makes up for the lack of consideration of source impact based on the LUR model. Remote sensing-derived variables were significantly correlated with gaseous pollutant concentrations such as SO2 and NO2. R2 values of the multiple linear regression equations for SO2, NO2 and PM10 were 0.78, 0.89 and 0.84, respectively, and the RMSE values were 0.32, 0.18 and 0.21, respectively. Model predictions at validation monitoring sites went well with predictions generally within 15% of measured values. Compared to the relationship between dependent variables and simple variables (such as traffic variables or meteorological condition variables), the relationship between dependent variables and integrated variables was more consistent with a linear relationship. Such integration has a discernable influence on both the overall model prediction and health effects assessment on the spatial distribution of air pollution in the city region.Li Chen Yuming Wang Peiwu Li Yaqin Ji Shaofei Kong Zhiyong Li Zhipeng Bai 2012Journal of Environmental Sciences2012,24,7:7
3Comparison of laparoscopically assisted and open radical distal gastrectomy with extended lymphadenectomy for gastric cancer management显示文摘W. Ziqiang Q. Feng C. Zhimin W. Miao Q. Lian L. Huaxing Y. Peiwu 2006Surgical Endoscopy2006,,11:2
4Chemical composition of walnuts from three regions in China显示文摘To reveal the characteristic chemicals of walnuts from different origins, we analyzed fatty acid composition,tocopherols, phytosterols and total phenolic content (TPC) of walnuts from three main producing regions inChina. The results showed that walnuts were rich in polyunsaturated fatty acids, and the ratio of ω-6 to ω-3 fattyacids was close to the recommendation of Chinese Nutrition Society. Moreover, walnuts contain high contents oftocopherols (331.20–414.71 mg/kg), phytosterols (97.17–110.35 mg/100 g) and phenols (38.51–48.08 mg GAE/kg). Significant chemical differences exist among walnuts from three production regions. The highest content ofpolyunsaturated fatty acids was found in walnuts from the northern China, the highest content of tocopherols inwalnuts from southwest China, and the highest contents of phytosterol and TPC in walnuts from northwest China.However, there was no significant difference in the tocopherol, phytosterol and TPC content of walnuts betweenthe Northern China and Northwest China. The above results provide important references for manufacturers andconsumers to select suitable walnut scientifically and reasonably.Min Liu Xueyan Wang Yu Zhang Lin Xu Yan Liu Li Yu Fei Ma Xuefang Wang Zhiyong Gong Liangxiao Zhang Peiwu Li 2023Oil Crop Science2023,8,1:2
5Development of a class-specific monoclonal antibody-based ELISA for aflatoxins in peanut显示文摘Peiwu Li Qi Zhang Wen Zhang Jinyang Zhang Xiaomei Chen Jun Jiang Lihua Xie Daohong Zhang 2008Food Chemistry2008,,1:2
6Multi-component immunochromatographic assay for simultaneous detection of aflatoxin B 1 , ochratoxin A and zearalenone in agro-food显示文摘Xin Li Peiwu Li Qi Zhang Ran Li Wen Zhang Zhaowei Zhang Xiaoxia Ding Xiaoqian Tang 2013Biosensors and Bioelectronics2013,,:2
7Comparison of laparoscopically assisted and open radical distal gastrectomy with extended lymphadenectomy for gastric cancer management显示文摘W. Ziqiang Q. Feng C. Zhimin W. Miao Q. Lian L. Huaxing Y. Peiwu 2006Surgical Endoscopy2006,,11:2
8Adulteration detection of edible oils with castor oil by gas chromatography显示文摘Wei HU Xuefang WANG Liangxiao ZHANG Peiwu LI Xiaoman SUN Jun JIANG Xiaoxia DING Qi ZHANG 2016Oil Crop Science2016,1,2:2
9An ultra-sensitive monoclonal antibody-based competitive enzyme immunoassay for aflatoxin M 1 in milk and infant milk products显示文摘Di Guan Peiwu Li Qi Zhang Wen Zhang Daohong Zhang Jun Jiang 2010Food Chemistry2010,,4:2
10Aflatoxin B1 in post-harvest peanuts and dietary risk in China显示文摘Xiaoxia Ding Peiwu Li Yizhen Bai 0,,:1
11A competitive immunoassay with a surrogate calibrator curve for aflatoxinM1 in milk显示文摘Di Guan Peiwu Li Yehan Cui 0,,:1
12Analytical approaches for measuring pestMdes, mycotoxins and heavy metals in vegetable oils: A review显示文摘Ma Fei Wu Rao Li Peiwu 2015European Jouroxd of Lipid Sciee & Technology2015,118,:1
13General complications following laparoscopic-assised gastrectomy and analysis of techniques to manage them显示文摘Bo T Zhihong P Peiwu Y 2009Surg Endosc2009,23,8:1
14Multi-component immunochromatographic assay for simultaneous detection of aflatoxin B 1 , ochratoxin A and zearalenone in agro-food显示文摘Xin Li Peiwu Li Qi Zhang Ran Li Wen Zhang Zhaowei Zhang Xiaoxia Ding Xiaoqian Tang 2013Biosensors and Bioelectronics2013,,:1
15General complications following laparoscopic-assisted gastrectomy and analysis of techniques to manage them显示文摘Bo T Zhihong P Peiwu Y 2009Surg Endosc2009,23,8:1
16Effects of HIF-la On human gastric cancer cell apeptosis at different CO2 pressures显示文摘Yingxue H Hua z Peiwu Y 2009Clin Exp Med2009,9,5:1
17Comparison of laparoscopically assisted and open radical distal gastrectomy with extended lymphadenectomy for gastric cancer management显示文摘W. Ziqiang Q. Feng C. Zhimin W. Miao Q. Lian L. Huaxing Y. Peiwu 2006Surgical Endoscopy2006,,11:1
18Immunoassays for aflatoxin显示文摘Peiwu Li Qi Zhang Wen Zhang 2009Trends in Analytical Chemistry2009,28,9:1
19Development of a class-specific monoclonal antibody based ELISA for aflatoxins in peanut显示文摘Peiwu Li Qi Zhang Wen Zhang 2009Food Chemistry2009,115,1:1
20Production of ultrasensitive generic monoclonal antibodies against major aflatoxins using a modified two-step screening procedure显示文摘Daohong Zhang Peiwu Li Qi Zhang 2009Analytica chimica acta2009,636,1:1
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