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| 1 | Non-small cell lung cancer in China显示文摘In China,lung cancer is a primary cancer type with high incidence and mortality.Risk factors for lung cancer include tobacco use,family history,radiation exposure,and the presence of chronic lung diseases.Most early-stage non-small cell lung cancer(NSCLC)patients miss the optimal timing for treatment due to the lack of clinical presentations.Population-based nationwide screening programs are of significant help in increasing the early detection and survival rates of NSCLC in China.The understanding of molecular carcinogenesis and the identification of oncogenic drivers dramatically facilitate the development of targeted therapy for NSCLC,thus prolonging survival in patients with positive drivers.In the exploration of immune escape mechanisms,programmed cell death protein 1(PD-1)/programmed death-ligand 1(PD-L1)inhibitor monotherapy and PD-1/PD-L1 inhibitor plus chemotherapy have become a standard of care for advanced NSCLC in China.In the Chinese Society of Clinical Oncology’s guidelines for NSCLC,maintenance immunotherapy is recommended for locally advanced NSCLC after chemoradiotherapy.Adjuvant immunotherapy and neoadjuvant chemoimmunotherapy will be approved for resectable NSCLC.In this review,we summarized recent advances in NSCLC in China in terms of epidemiology,biology,molecular pathology,pathogenesis,screening,diagnosis,targeted therapy,and immunotherapy。 | Peixin Chen Yunhuan Liu Yaokai Wen Caicun Zhou | 2022 | Cancer Communications2022，42，10： | 29 |
| 2 | Vibration analysis and control technologies of hydraulic pipeline system in aircraft:A review显示文摘Vibrations in aircraft hydraulic pipeline system,due to multi-source excitation of high fluid pressure fluctuation and serious vibration environment of airframe,can cause the pipeline system vibration failures through overload in engineering field.Controlling the vibrations in hydraulic pipeline is a challenging work to ensure the flight safety of aircraft.The common vibration control technologies have been demonstrated to be effective in typical structures such as aerospace structures,shipbuilding structures,marine offshore structures,motor structures,etc.However,there are few research literatures on vibration control strategies of aircraft hydraulic pipeline.Combining with the development trend of aircraft hydraulic pipeline system and the requirement of vibration control technologies,this paper provides a detailed review on the current vibration control technologies in hydraulic pipeline system.A review of the general approaches following the passive and active control technologies are presented,which are including optimal layout technique of pipeline and clamps,constrained layer damping technique,vibration absorber technique,hydraulic hose technique,optimal pump structure technique,and active vibration control technique of pipeline system.Finally,some suggestions for the application of vibration control technologies in engineering field are given. | Peixin GAO Tao YU Yuanlin ZHANG Jiao WANG Jingyu ZHAI | 2021 | Chinese Journal of Aeronautics2021，34，4： | 19 |
| 3 | Pigeon-inspired optimization:a new swarm intelligence optimizer for air robot path planning显示文摘Purpose–The purpose of this paper is to present a novel swarm intelligence optimizer—pigeoninspired optimization(PIO)—and describe how this algorithm was applied to solve air robot path planning problems.Design/methodology/approach–The formulation of threat resources and objective function in air robot path planning is given.The mathematical model and detailed implementation process of PIO is presented.Comparative experiments with standard differential evolution(DE)algorithm are also conducted.Findings–The feasibility,effectiveness and robustness of the proposed PIO algorithm are shown by a series of comparative experiments with standard DE algorithm.The computational results also show that the proposed PIO algorithm can effectively improve the convergence speed,and the superiority of global search is also verified in various cases.Originality/value–In this paper,the authors first presented a PIO algorithm.In this newly presented algorithm,map and compass operator model is presented based on magnetic field and sun,while landmark operator model is designed based on landmarks.The authors also applied this newly proposed PIO algorithm for solving air robot path planning problems. | Haibin Duan Peixin Qiao | 2014 | International Journal of Intelligent Computing and Cybernetics2014，7，1： | 17 |
| 4 | 重载列车牵引、调速及紧急制动的纵向力──大秦线万吨列车试验研究显示文摘1990年5月在大秦线西段,进行了我国万吨级重载列车静置制动和线路运行试验。本文着重分析万吨列车在起动、长大下坡调速制动运行以及紧急制动工况下列车的纵向力及其规律,并与计算机模拟结果对比。同时也讨论了制动波速、长大下坡时列车充气能力及紧急制动距离等问题。这些研究结果为今后在我国开行万吨列车减小纵向冲动、防止断钩、保证安全运行提供了重要的科学依据。 | Fan Peixin(Res.Inst .of Rail Vehicles.Southwest Jiaotong University,Chengdu 610031.China) | 1994 | 西南交通大学学报1994，29，1： | 11 |
| 5 | Birth defects in pregestational diabetes:Defect range,glycemic threshold and pathogenesis显示文摘Currently,60 million women of reproductive age(18-44 years old) worldwide,and approximately 3 million American women have diabetes mellitus,and it has been estimated that this number will double by 2030.Pregestational diabetes mellitus(PGD) is a significant public health problem that increases the risk for structural birth defects affecting both maternal and neonatal pregnancy outcome.The most common types of human structural birth defects associated with PGD are congenital heart defects and central nervous system defects.However,diabetes can induce birth defects in any other fetal organ.In general,the rate of birth defects increases linearly with the degree of maternal hyperglycemia,which is the major factor that mediates teratogenicity of PGD.Stringent prenatal care and glycemic control are effective means to reduce birth defects in PGD pregnancies,but cannot reduce the incidence of birth defects to the rate of that is seen in the nondiabetic population.Studies in animal models have revealed that PGD induces oxidative stress,which activates cellular stress signalling leading to dysregulation of gene expression and excess apoptosis in the target organs,including the neural tube and embryonic heart.Activation of the apoptosis signalregulating kinase 1(ASK1)-forkhead transcription factor 3a(Fox O3a)-caspase 8 pathway causes apoptosis in the developing neural tube leading to neural tube defects(NTDs).ASK1 activates the c-Jun-N-Terminal kinase 1/2(JNK1/2),which leads to activation of the unfolded protein response and endoplasmic reticulum(ER) stress.Deletion of the ASK1 gene,the JNK1 gene,or the JNK2 gene,or inhibition of ER stress by 4-Phenylbutyric acid abrogates diabetes-induced apoptosis and reduces the formation of NTDs.Antioxidants,such as thioredoxin,which inhibits the ASK1-Fox O3a-caspase 8 pathway or ER stress inhibitors,may prevent PGD-induced birth defects. | Rinat Gabbay-Benziv E Albert Reece Fang Wang Peixin Yang | 2015 | World Journal of Diabetes2015，6，3： | 10 |
| 6 | In situ construction of porous hierarchical(Ni3-xFex)FeN/Ni heterojunctions toward efficient electrocatalytic oxygen evolution显示文摘As a choke point in water electrolysis,the oxygen evolution reaction(OER)suffers from the severe electrode polarization and large overpotential.Herein,the porous hierarchical hetero-(Nis Fe)FeN/Ni catalysts are in situ constructed for the eficient electrocatalytic OER.X-ray absorption fine structure characterizations reveal the strong Ni-Fe bimetallic interaction in(Niz Fex)FeN/Ni.Theoretical study indicates the heterojunction and bimetallic interaction decrease the free-energy change for the rate-limiting step of the OER and the overpotential thereof.In addition,the high conductivity and porous hierarchical morphology favor the electron transfer,electrolyte access and O2 release.Consequently,the optimized catalyst achieves a low overpotential of 223 mV at 10 mA.cm^-2,a small Tafel slope of 68 mV:dec^-1,and a high stability.The excellent performance of the optimized catalyst is also demonstrated by the overall water electrolysis with a low working voltage and high Faradaic efficiency.Moreover,the correlation between the structure and performance is well established by the experimental characterizations and theoretical calculations,which confirms the origin of the OER activity from the surface metal oxyhydroxide in situ generated upon applying the current.This study suggests a promising approach to the advanced OER electrocatalysts for practical applications by constructing the porous hierarchical metal-compound/metal heterojunctions. | Minglei Yan Kun Mao Peixin Cui Chi Chen Jie Zhao Xizhang Wang Lijun Yang Hui Yang Qiang Wu Zheng Hu | 2020 | Nano Research2020，13，2： | 8 |
| 7 | Effect of miniscalpel-needle on relieving the pain of myofascial pain syndrome: a systematic review显示文摘OBJECTIVE: To evaluate the effect and safety of miniscalpel-needle(MSN) on reducing the pain of myofascial pain syndrome(MPS).METHODS: We reviewed the available literatures inception up to February 2014 using Pubmed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure Database, Chinese Biomedical Database and Wanfang Database.RESULTS: Eight randomized controlled trials were finally identified. The main controls involved acupuncture, medications, injection, massage and cupping. We found that all of the studies agreed on the potential benefit of MSN as a strategy for MPS and the superiority compared to the controls, however,randomized methods applied in most of the trials could be criticized for their high or unclear risk of bias. Further research is also needed to clarify questions around the appropriate frequency and number of treatment sessions of MSN.CONCLUSION: This review shows that MSN might have the effect on MPS, even though there were some limitations in the studies included in the review. Studies with robust methodology are warranted to further test its pain-relieving effect on MPS. | Liu Tong Peng Yuanyuan Zhu Shipeng Chen Huan Li Fuyun Hong Peixin Cao Bingyan Peng Bo Fan Yifan Chen Yupei Zhang Li | 2015 | Journal of Traditional Chinese Medicine2015，35，6： | 6 |
| 8 | Lead-free thermochromic perovskites with tunable transition temperatures for smart window applications显示文摘The structural flexibility of hybrid perovskite materials allows for phase transition and consequently thermochromic properties.Here we investigate the thermochromic performance in a series of copper-based layered perovskites with organic cations having different alky chain lengths. Their transition temperature is found to be dependent on the organic cations due to molecular motion and hydrogen bond interaction, providing possibilities to prepare thermochromic semiconductors near room temperature for smart window applications. | Jingwen Li Xiaolong Liu Peixin Cui Junmeng Li Tao Ye Xi Wang Chuang Zhang Yong Sheng Zhao | 2019 | Science China Chemistry2019，62，9： | 6 |
| 9 | Adaptive widths of the approximation functional on the Sobolev space W_2~r with Gaussian measure显示文摘The tight orders for the Kolmogorov and adaptive (n,ε,δ)-widths of the Sobolev spaces Wr2 equipped with a Gaussian measure in the L1-norm and L∞-norm are determined by the method of discretization, which is based on reducing the calculation of the (n,ε,δ)-widths of the Sobolev space to the calculation of (n,ε,δ)-widths of finite-dimensional set equipped with the Gaussian measure. | FANG Gensun and YE Peixin(Department of Mathematics, Beijing Normal University, Beijing 100875, China) | 2002 | Progress in Natural Science:Materials International2002，12，7： | 4 |
| 10 | Influence of Alumina Content on Catalytic Performance of PtSn/Al_2O_3/SBA-15 Catalysts for Propane Dehydrogenation显示文摘The alumina-modified SBA-15 (Al2O3/SBA-15) zeolite was prepared in a non-aqueous system by using toluene as the solvent, and was used to support the PtSn-based catalyst for propane dehydrogenation. The BET surface area measurements, hydrogen chemisorption, FT-IR spectroscopy, NH3-TPD, XPS and TPO techniques were used to characterize the catalysts. Test results showed that the addition of alumina not only could modify the acid function of the support but also the structure of the metallic phase, thus affecting their catalytic properties. Among these catalysts studied, the PtSn/Al2O3 (5%)/SBA-15 catalyst exhibited a best catalytic performance in terms of propane conversion and selectivity to propene. The high catalytic performance might be attributed to the relatively good Pt metal dispersion and/or the strong interaction between Pt and Sn species. | Zhang Peixin Zhou Yuming Duan Yongzheng Zhang Yiwei Sheng Xiaoli | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，4： | 4 |
| 11 | Discriminating characters of ore-forming intrusions in the super-large Chalukou porphyry Mo deposit,NE China显示文摘The Chalukou porphyry Mo deposit, located in the Great Hinggan Range, is the largest Mo deposit in northeast China, although the age and genesis of the associated magmatic intrusions remain debated.Here we report zircon U-Pb ages and trace elements, whole rock geochemistry and Sre Nd isotope data with a view to understand the relationship between the magmatism and molybdenum mineralization.Zircon U-Pb analysis yield an age of 475 Ma for rhyolite in the older strata, 168 Ma for the premineralization monzogranite, and 154 Ma for the syn-mineralization granite porphyry. The granite porphyry and quartz porphyry are considered as the ore-forming intrusions. These rocks are peraluminous, alkali-calcic, and belong to high-K to shoshonitic series with a strong depletion of Eu. They also display characteristics of I-type granites. The rocks exhibit wide variations of(87 Sr/86 Sr)iin the range of 0.705426 -0.707363, and ε_(Nd)(t) of -3.7 to 0.93. Zircon REE distribution patterns show characteristics between crust and the mantle, implying magma genesis through crust-mantle interaction. The Fe_2O_3/FeO values(average 1) for the whole rock and EuN/Eu*Nvalues(average 0.45), Ce^(4+)/Ce^(3+) values(average 301)for zircon grains from the granite porphyry are higher than those from other lithologies. These features suggest that the ore-forming intrusions(syn-mineralization porphyry) had higher oxygen fugacity conditions than those of the pre-mineralization and post-mineralization rocks. The Chalukou Mo deposit formed in relation to the southward subduction of the Mongol-Okhotsk Ocean. Our study suggests that the subduction-related setting, crust-mantle interaction, and the large-scale magmatic intrusion were favorable factors to generate the super-large Mo deposits in this area. | Peixin Duan Cui Liu Xuanxue Mo Jinfu Deng Jinhua Qin Yu Zhang Shipan Tian | 2018 | Geoscience Frontiers2018，9，5： | 3 |
| 12 | A Multifunctional Anti-Proton Electrolyte for High-Rate and Super-Stable Aqueous Zn-Vanadium Oxide Battery显示文摘Large volumetric expansion of cathode hosts and sluggish transport kinetics in the cathode–electrolyte interface,as well as dendrite growth and hydrogen evolution at Zn anode side are considered as the system problems that cause the electrochemical failure of aqueous Zn-vanadium oxide battery.In this work,a multifunctional anti-proton electrolyte was proposed to synchronously solve all those issues.Theoretical and experimental studies confirm that PEG 400 additive can regulate the Zn^(2+) solvation structure and inhibit the ionization of free water molecules of the electrolyte.Then,smaller lattice expansion of vanadium oxide hosts and less associated by-product formation can be realized by using such electrolyte.Besides,such electrolyte is also beneficial to guide the uniform Zn deposition and suppress the side reaction of hydrogen evolution.Owing to the integrated synergetic modifica-tion,a high-rate and ultrastable aqueous Zn-V_(2)O_(3)/C battery can be constructed,which can remain a specific capacity of 222.8 m Ah g^(-1)after 6000 cycles at 5 A g^(-1),and 121.8 m Ah g^(-1) even after 18,000 cycles at 20 A g^(-1),respectively.Such“all-in-one”solution based on the electrolyte design provides a new strategy for developing high-performance aqueous Zn-ion battery. | Yangwu Chen Dingtao Ma Kefeng Ouyang Ming Yang Sicheng Shen Yanyi Wang Hongwei Mi Lingna Sun Chuanxin He Peixin Zhang | 2022 | Nano-Micro Letters2022，14，9： | 3 |
| 13 | Research on BP Neural Network Algorithm Based on Quasi- Newton Method显示文摘 | Lu Peixin | 2014 | International Journal of Technology Management2014，，7： | 3 |
| 14 | Instrumental Variable Type Estimation for Generalized Varying Coefficient Models with Error-Prone Covariates显示文摘In this paper,the estimation for a class of generalized varying coefficient models with error-prone covariates is considered.By combining basis function approximations with some auxiliary variables,an instrumental variable type estimation procedure is proposed.The asymptotic results of the estimator,such as the consistency and the weak convergence rate,are obtained.The proposed procedure can attenuate the effect of measurement errors and have proved workable for finite samples. | ZHAO Peixin | 2013 | Wuhan University Journal of Natural Sciences2013，18，3： | 2 |
| 15 | A multi-point collaborative DDoS defense mechanism for IIoT environment显示文摘Nowadays,a large number of intelligent devices involved in the Industrial Internet of Things(IIoT)environment are posing unprecedented cybersecurity challenges.Due to the limited budget for security protection,the IIoT devices are vulnerable and easily compromised to launch Distributed Denial-of-Service(DDoS)attacks,resulting in disastrous results.Unfortunately,considering the particularity of the IIoT environment,most of the defense solutions in traditional networks cannot be directly applied to IIoT with acceptable security performance.Therefore,in this work,we propose a multi-point collaborative defense mechanism against DDoS attacks for IIoT.Specifically,for the single point DDoS defense,we design an edge-centric mechanism termed EdgeDefense for the detection,identification,classification,and mitigation of DDoS attacks and the generation of defense information.For the practical multi-point scenario,we propose a collaborative defense model against DDoS attacks to securely share the defense information across the network through the blockchain.Besides,a fast defense information sharing mechanism is designed to reduce the delay of defense information sharing and provide a responsive cybersecurity guarantee.The simulation results indicate that the identification and classification performance of the two machine learning models designed for EdgeDefense are better than those of the state-of-the-art baseline models,and therefore EdgeDefense can defend against DDoS attacks effectively.The results also verify that the proposed fast sharing mechanism can reduce the propagation delay of the defense information blocks effectively,thereby improving the responsiveness of the multi-point collaborative DDoS defense. | Hongcheng Huang Peixin Ye Min Hu Jun Wu | 2023 | Digital Communications and Networks2023，9，2： | 2 |
| 16 | Strong controls of daily minimum temperature on the autumn photosynthetic phenology of subtropical vegetation in China显示文摘Background:Vegetation phenology research has largely focused on temperate deciduous forests,thus limiting our understanding of the response of evergreen vegetation to climate change in tropical and subtropical regions.Results:Using satellite solar-induced chlorophyll fluorescence(SIF)and MODIS enhanced vegetation index(EVI)data,we applied two methods to evaluate temporal and spatial patterns of the end of the growing season(EGS)in subtropical vegetation in China,and analyze the dependence of EGS on preseason maximum and minimum temperatures as well as cumulative precipitation.Our results indicated that the averaged EGS derived from the SIF and EVI based on the two methods(dynamic threshold method and derivative method)was later than that derived from gross primary productivity(GPP)based on the eddy covariance technique,and the time-lag for EGSsif and EGSevi was approximately 2 weeks and 4 weeks,respectively.We found that EGS was positively correlated with preseason minimum temperature and cumulative precipitation(accounting for more than 73%and 62%of the study areas,respectively),but negatively correlated with preseason maximum temperature(accounting for more than 59%of the study areas).In addition,EGS was more sensitive to the changes in the preseason minimum temperature than to other climatic factors,and an increase in the preseason minimum temperature significantly delayed the EGS in evergreen forests,shrub and grassland.Conclusions:Our results indicated that the SIF outperformed traditional vegetation indices in capturing the autumn photosynthetic phenology of evergreen forest in the subtropical region of China.We found that minimum temperature plays a significant role in determining autumn photosynthetic phenology in the study region.These findings contribute to improving our understanding of the response of the EGS to climate change in subtropical vegetation of China,and provide a new perspective for accurately evaluating the role played by evergreen vegetation in the regional carbon budget. | Peixin Ren Zelin Liu Xiaolu Zhou Changhui Peng Jingfeng Xiao Songhan Wang Xing Li Peng Li | 2021 | Forest Ecosystems2021，8，3： | 2 |
| 17 | Global classical solution to the three-dimensional isentropic compressible Navier-Stokes equations with general initial data显示文摘We establish the global existence and uniqueness of classical solutions to the Cauchy problem for the isentropic compressible Navier-Stokes equations in the three space dimensions with general initial data which could be either vacuum or non-vacuum under the assumption that the viscosity coefficient μ is large enough. | DENG XueMei ZHANG PeiXin ZHAO JunNing | 2012 | Science China Mathematics2012，55，12： | 2 |
| 18 | Fully fluid-solid coupling dynamic model for seismic response of underground structures in saturated soils显示文摘The seismic response characteristics of underground structures in saturated soils are investigated.A fully fluid-solid coupling dynamic model is developed and implemented into ABAQUS with a user-defined element to simulate the dynamic behavior of saturated soils.The accuracy of the model is validated using a classic example in literature.The performance of the model is verified by its application on simulating the seismic response characteristics of a subway station built in saturated soils.The merits of the model are demonstrated by comparing the difference of the seismic response of an underground structure in saturated soils between using the fully coupling model and a single-phase medium model.The study finds that the fully coupling model developed herein can simulate the dynamic response characteristics of the underground structures in saturated soils with high accuracy.The seismic response of the underground structure tends to be underestimated by using the single-phase medium model compared with using the fully coupling model,which provides a weaker confining action to the underground structure. | Li Liang Jiao Hongyun Du Xiuli Shi Peixin | 2020 | Earthquake Engineering and Engineering Vibration2020，19，2： | 2 |
| 19 | Microstructure design of C/C composites through electrochemical corrosion for brazing to Nb显示文摘Surface structure of C/C composites has been regulated through electrochemical corrosion at room temperature to modify the residual stress and improve the joining strength when brazed to Nb.The unique crevice corrosion in C/C composites is investigated to reveal the change of corrosion depth and fiber size.The interlacing zone of carbon fiber reinforced brazing alloy replaces the reaction layer in the original joint.Joining area is increased dramatically and the continuous crack will be hindered.The interlacing zone eliminates the stress concentration and relieves the residual stress through reducing the property mismatch.All advantages contribute to the joining quality of C/C–Nb.Shear strength of C/C–Nb joint with 80μm depth reached 37.7 MPa,which was 1.2 times higher than that of original joint.Surface structure design of C/C composites not only expands the application in structure component,but also exhibits the promising application in energy field. | Jin Ba Xu Ji Bin Wang Peixin Li Jinghuang Lin Jian Cao Junlei Qi | 2022 | Journal of Materials Science & Technology2022，，9： | 2 |
| 20 | Optimal query error of quantum approximation on some Sobolev classes显示文摘We study the approximation of the imbedding of functions from anisotropic and general-ized Sobolev classes into Lq([0,1]d) space in the quantum model of computation. Based on the quantum algorithms for approximation of finite imbedding from LpN to LNq , we develop quantum algorithms for approximating the imbedding from anisotropic Sobolev classes B(Wpr ([0,1]d)) to Lq([0,1]d) space for all 1 q,p ∞ and prove their optimality. Our results show that for p < q the quantum model of computation can bring a speedup roughly up to a squaring of the rate in the classical deterministic and randomized settings. | SONG ZhanJie YE PeiXin | 2008 | Science China Mathematics2008，51，9： | 2 |
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