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| 1 | Global leaf nitrogen and phosphorus stoichiometry and their scaling exponent显示文摘Leaf nitrogen(N) and phosphorus(P) concentrations constrain photosynthetic and metabolic processes,growth and the productivity of plants. Their stoichiometry and scaling relationships regulate the allocation of N and P from subcellular to organism, and even ecosystem levels, and are crucial to the modelling of plant growth and nutrient cycles in terrestrial ecosystems. Prior work has revealed a general biogeographic pattern of leaf N and P stoichiometric relationships and shown that leaf N scales roughly as two-thirds the power of P. However, determining whether and how leaf N and P stoichiometries, especially their scaling exponents, change with functional groups and environmental conditions requires further verification. In this study, we compiled a global data set and documented the global leaf N and P concentrations and the N:P ratios by functional group, climate zone and continent. The global overall mean leaf N and P concentrations were 18.9 mg g^(-1) and 1.2 mg g^(-1), respectively, with significantly higher concentrations in herbaceous than woody plants(21.72 mg g^(-1) vs. 18.22 mg g^(-1) for N; and 1.64 mg g^(-1) vs. 1.10 mg g^(-1) for P). Both leaf N and P showed higher concentrations at high latitudes than low latitudes. Among six continents, Europe had the highest N and P concentrations(20.79 and 1.54 mg g^(-1)) and Oceania had the smallest values(10.01 and 0.46 mg g^(-1)). These numerical values may be used as a basis for the comparison of other individual studies. Further, we found that the scaling exponent varied significantly across different functional groups,latitudinal zones, ecoregions and sites. The exponents of herbaceous and woody plants were 0.659 and0.705, respectively, with significant latitudinal patterns decreasing from tropical to temperate to boreal zones. At sites with a sample size ≥10, the values fluctuated from 0.366 to 1.928, with an average of 0.841.Several factors including the intrinsic attributes of different life forms, P-related growth rates and relative nutrient availability of soils likely account for the inconstant exponents of leaf N vs. P scaling relationships. | Di Tian Zhengbing Yan Karl J.Niklas Wenxuan Han Jens Kattge Peter B.Reich Yongkai Luo Yahan Chen Zhiyao Tang Huifeng Hu Ian J.Wright Bernhard Schmid Jingyun Fang | 2018 | National Science Review2018，5，5： | 24 |
| 2 | Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy. | Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz | 2010 | World Journal of Gastroenterology2010，16，8： | 10 |
| 3 | Copper toxicosis gene MURRl is not changed in Wilson disease patients with normal blood ceruloplasmin levels显示文摘瞄准:在为 MURR1 编码的基因为改变分析我们的威尔森疾病病人队(n=106 ) 。方法:有威尔森疾病的确定的诊断的病人但是正常血浆铜蓝蛋白血层次为我们的学习被选择(n = 14 ) 。有在 ATP7B 基因的二个已知的引起疾病的变化的病人没被包括。人的 MURR1 基因的三前 ons 被聚合酶链反应在 genomic DNA 的扩大以后定序。结果:我们的学习没揭示在威尔森疾病病人的 MURR1 顺序导致一个氨基酸变化的任何变化。在编码顺序的 472 bp 的多型性能被证实。结论:MURR1 基因不与正常浆液血浆铜蓝蛋白层次在威尔森疾病病人的致病起作用。 | Karl Heinz Weiss Uta Merle Mark Schaefer Peter Ferenci Joachim Fullekrug Wolfgang Stremmel | 2006 | World Journal of Gastroenterology2006，12，14： | 4 |
| 4 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 5 | 带冷却段的中密度纤维板连续压机显示文摘 | Marius Barbu Dieter Hoepner Karl Lerach Helmut Roll Peter Beck Ulrich Kaiser | 2002 | 林产工业2002，29，2： | 3 |
| 6 | What drives corporate liquidity? An international survey of cash holdings and lines of credit显示文摘 | Karl V. Lins Henri Servaes Peter Tufano | 2010 | Journal of Financial Economics2010，，1： | 3 |
| 7 | Peroral Endoscopic Myotomy for the Treatment of Achalasia: An International Prospective Multicenter Study显示文摘 | Daniel Von Renteln Karl–Hermann Fuchs Paul Fockens Peter Bauerfeind Melina C. Vassiliou Yuki B. Werner Gerald Fried Wolfram Breithaupt Henriette Heinrich Albert J. Bredenoord Jan F. Kersten Tessa Verlaan Michael Trevisonno Thomas R?sch | 2013 | Gastroenterology2013，，2： | 2 |
| 8 | Anti-Fas/Apo-1 antibody-mediated apoptosis of cultured human glioma cells显示文摘 | Karl F Peter G | 1994 | J Clin Invest1994，94，： | 1 |
| 9 | Ultrasound biomicroscopy in chronic ocular hypotony:its impact on diagnosis and management显示文摘 | Sigrid R Peter S Bert E Karl BS Gunter K | 2002 | Retina2002，22，5： | 1 |
| 10 | Cost-effectiveness of FDG-PET for the management of potentially operable non-small cell lung cancer: priority for a PET-based strategy after nodal-negative CT results显示文摘 | Markus Dietlein Kerstin Weber Afschin Gandjour Detlef Moka Peter Theissen Karl W. Lauterbach Harald Schicha | 2000 | European Journal of Nuclear Medicine2000，，11： | 1 |
| 11 | Outcome analysis of long-term survivors following pancreaticoduodenectomy显示文摘 | W. Scott Melvin M.D. Karl S. Buekers B.S. Peter Muscarella M.D. Jerome A. Johnson Ph.D. William J. Schirmer M.D. E. Christopher Ellison M.D | 1998 | Journal of Gastrointestinal Surgery1998，，1： | 1 |
| 12 | Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma显示文摘 | Matthias L?hr Anne Hoffmeyer Jens-Christian Kr?ger Mathias Freund Johannes Hain Albrecht Holle Peter Karle Wolfram T Kn?fel Stefan Liebe Petra Müller Horst Nizze Matthias Renner Robert M Saller Thomas Wagner Karlheinz Hauenstein Walter H Günzburg Brian Sa | 2001 | The Lancet2001，，9268： | 1 |
| 13 | Near-and mid-infrared laser-optical sensors for gas analysis显示文摘 | Peter Werlea Franz Slemra Karl Maurera | 2002 | Optics and Lasers in Engineering2002，37，： | 1 |
| 14 | Computed tomographies and cancer risk in children: a literature overview of CT practices, risk estimations and an epidemiologic cohort study proposal显示文摘 | Lucian Krille Hajo Zeeb Andreas Jahnen Peter Mildenberger Michael Seidenbusch Karl Schneider Gerald Weisser Gael Hammer Peter Scholz Maria Blettner | 2012 | Radiation and Environmental Biophysics2012，，2： | 1 |
| 15 | Near and mid-infrared laser-optical sensors for gas analysis显示文摘 | Peter Werle Franz Slemr Karl Maurer | 2002 | Optics and Lasers in Engineering2002，37，： | 1 |
| 16 | Near-and mid-infrared laser-optical sensors for gasanalysis显示文摘 | Werle Peter Slemr Franz Karl Kormann Robert | 2002 | Optics and Lasers in Engineering2002，37，： | 1 |
| 17 | Surface roughness measurements of low-scatter mirror sand roughness standards 显示文摘 | Karl H G Peter G W Jean M B | 1984 | Applied Optics1984，23，21： | 1 |
| 18 | Effect of Cast and Noncast Foot Orthoses on Plantar Pressure and Force during Normal Gait显示文摘 | ANTHONY R PETER S B L KARL L | 2000 | Am Podiatr Med Assoc2000，90，9： | 1 |
| 19 | Mechanically milled Mg composites for hydrogen storage The transition to a steady state composition 显示文摘 | Peter Spatz Andreas Zuttel | 1996 | Journal of Alloys and Compounds1996，，240： | 1 |
| 20 | Iron coor- dination chemistry with tetra-, penta- and hexadentate bispi- dine-type ligands显示文摘 | Heidi Barzel Peter Comba Karl S Hagen | 2002 | Inorganica Chimica Acta2002，337，： | 1 |
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