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| 1 | Effect of probiotic Lactobacillus plantarum Dad-13 powder consumption on the gut microbiota and intestinal health of overweight adults显示文摘BACKGROUND Shifting on lifestyle,diet,and physical activity contributed on increasing number of obese people around the world.Multiple factors influence the development of obesity.Some research suggested that gut microbiota(GM)plays an important role in nutrient absorption and energy regulation of individuals,thus affecting their nutritional status.Report of Indonesia Basic Health Research showed that the prevalence of obesity in every province tended to increase.Although the root cause of obesity is excessive calorie intake compared with expenditure,the differences in gut microbial ecology between healthy and obese humans may affect energy homeostasis.GM affect body weight,especially obesity.Probiotics that are consumed while alive and able to colonize in the intestine are expected to increase the population of good bacteria,especially Bifidobacteria and Lactobacilli,and suppress pathogens such as Enterobacteriaceae and Staphylococcus.The strain of L.plantarum Dad-13 has been demonstrated to survive and colonize in the gastrointestinal tract of healthy Indonesian adults who consume fermented milk containing L.plantarum Dad-13.The consumption of probiotic L.plantarum Dad-13 powder decreased E.coli and non-E.coli coliform bacteria in school-aged children in Indonesia.L.plantarum is a dominant bacterium in the average Indonesian’s GM.For this reason,this bacterium is probably a more suitable probiotic for Indonesians.AIM To determine the effect of the consumption of indigenous probiotic Lactobacillus plantarum Dad-13 powder in overweight adults in Yogyakarta(Indonesia).METHODS Sixty overweight volunteers with a body mass index(BMI)equal to or greater than 25 consume indigenous probiotic powder L.plantarum Dad-13(2×109 CFU/gram/sachet)for 90 d.The study was a randomized,double-blind,placebocontrolled study.The volunteers filled in a diary on a daily basis,which consisted of questions on study product intake(only during ingestion period),other food intake,number of bowel movements,fecal quality(consistency and color),any medications received,and any symptom of discomfort,such as diarrhea,constipation,vomiting,gassing,sensation of illness,etc.Fecal samples and the subjects’diaries were collected on the morning of day 10+1,which was marked as the end of the baseline period and the start of the ingestion period.During the ingestion period(from day 11 to day 101),several parameters to measure and analyze the results included body weight and height(once a month),the lipid profile,GM analysis using MiSeq,short-chain fatty acid(SCFA)analysis using gas chromatography,and the measurement of fecal pH using a pH meter.RESULTS The consumption of indigenous probiotic powder L.plantarum Dad-13 caused the average body weight and BMI of the probiotic group to decrease from 84.54±17.64 kg to 83.14±14.71 kg and 33.10±6.15 kg/m2 to 32.57±5.01 kg/m2,respectively.No significant reduction of body weight and BMI in the placebo group was observed.An analysis of the microbiota showed that the number of Bacteroidetes,specifically Prevotella,increased significantly,while that of Firmicutes significantly decreased.No significant change in lipid profile in both groups was found.Also,no significant change in SCFAs(e.g.,butyrate,propionate,acetic acid)and pH level was found after the consumption of the probiotic.CONCLUSION No significant differences in pH before and after ingestion were observed in both the probiotic and placebo groups as well as in the lipid profile of both cholesterol and triglyceride,high-density lipoprotein(HDL),low-density lipoprotein(LDL),and the LDL/HDL ratio.In addition,no significant changes in the concentration of SCFAs(e.g.,acetic acid,propionate,and butyrate)were found after consumption.Interestingly,a significant decrease in body weight and BMI(P<0.05)was determined in the treatment group.An analysis of GM shows that L.plantarum Dad-13 caused the Firmicutes population to decrease and the Bacteroidetes population(especially Prevotella)to increase. | Endang Sutriswati Rahayu Mariyatun Mariyatun Nancy Eka Putri Manurung Pratama Nur Hasan Phatthanaphong Therdtatha Riko Mishima Husnita Komalasari Nurul Ain Mahfuzah Fathyah Hanum Pamungkaningtyas Wahyu Krisna Yoga Dina Aulia Nurfiana Stefanie Yolanda Liwan Mohammad Juffrie Agung Endro Nugroho Tyas Utami | 2021 | World Journal of Gastroenterology2021，27，1： | 6 |
| 2 | Gut microbiota profile in healthy Indonesians显示文摘BACKGROUND Recently, gut microbiota has been associated with various diseases other than intestinal disease. Thus, there has been rapid growth in the study of gut microbiota. Considering the numerous factors influencing gut microbiota such as age, diet, etc., area-based research is required. Indonesia has numerous different tribes and each of these tribes have different lifestyles. Hence, it is expected that each tribe has a specific gut microbiota. A deeper insight into the composition of gut microbiota can be used to determine the condition of gut microbiota in Indonesians and to consider which treatment may be suitable and effective to improve health status.AIM To investigate the gut microbiota of Indonesian subjects represented by Javanese and Balinese tribes by analyzing fecal samples.METHODS Fecal samples were collected from a total of 80 individuals with 20 in each of the young groups ranging from 25-45 years and the elderly group aged 70 years or more from two different regions, Yogyakarta and Bali. Fecal sample collection was performed at the end of the assessment period(day 14 ± 1 d) during which time the subjects were not allowed to consume probiotic or antibiotic products.The quantification of various Clostridium subgroups, Lactobacillus subgroups,Enterococcus, Streptococcus, Staphylococcus, Bacteroides fragilis group and Prevotella,Bifidobacterium and Atopobium cluster, Enterobacteriaceae and Pseudomonas was performed using the Yakult intestinal flora-scan(YIF-SCAN).RESULTS The bacterial population in younger subjects' feces was higher than that in the elderly population, with a total of approximately 10.0 – 10.6 log10 bacterial cells/g feces. The most abundant bacteria in all groups were Clostridium, followed by Prevotella, Atopobium, Bifidobacterium and Bacteroides. In the elderly, an increase in Enterobacteriaceae, Coliform and Escherichia coli was found. In terms of bacterial counts in Yogyakarta, total bacteria, Clostridium coccoides(C. coccoides) group,Bifidobacterium, Prevotella, Lactobacillus plantarum subgroup, and Streptococcus were significantly higher(P < 0.05) in younger than elderly subjects, while the Lactobacillus gasseri subgroup, Lactobacillus casei subgroup, and Lactobacillus reuteri subgroup counts were significantly lower(P < 0.05) in younger subjects. In Balinese subjects, total bacteria, C. coccoides group, Clostridium leptum subgroup,Bacteroides fragilis group, and Prevotella were significantly higher(P < 0.05) in younger compared to elderly individuals, while the Lactobacillus ruminis subgroup, and Enterobacteriaceae were significantly lower(P < 0.05) in younger subjects. The results also revealed that, besides the C. coccoides group and Clostridium leptum group being the most abundant gut microbiota in both Yogyakarta and Balinese people, the latter was indicated by a higher Clostridium perfringens count, which was almost 10 times that of Yogyakarta subjects. This may be a response to different lifestyles in the different tribes; however, this phenomenon requires further extensive study.CONCLUSION Bacterial populations were higher in younger than in elderly subjects. Most abundant bacterial groups were Clostridium, Prevotella, Atopobium, Bifidobacterium,and Bacteroides. The level of Clostridium perfringens in Yogyakarta subjects was lower than that in Balinese subjects. | Endang Sutriswati Rahayu Tyas Utami Mariyatun Mariyatun Pratama Nur Hasan Rafli Zulfa Kamil Ryan Haryo Setyawan Fathyah Hanum Pamungkaningtyas IskANDar Azmy Harahap Devin Varian Wiryohanjoyo Putrika Citta Pramesi Muhammad Nur Cahyanto I Nengah Sujaya Mohammad Juffrie | 2019 | World Journal of Gastroenterology2019，25，12： | 6 |
| 3 | A Video Streaming Application Using Mobile Media Application Programming Interface显示文摘 | Shiddiqi A M Pratama H Ciptaningtyas H T | 2010 | Telkomnika2010，8，3： | 1 |
| 4 | How to manage multiple fi- broids in reproductive laparoscopic surgery 显示文摘 | Hadisaputra W Pratama A | 2013 | Gyneeol Minim Inva Ther2013，2，4： | 1 |
| 5 | Changes in culture expanded human amniotic epithelial cells:implications for potential therapeutic applications显示文摘 | Pratama G Vaghjiani V Tee JY | | 0，，11： | 1 |
| 6 | A Video Streaming Application Using Mobile Media Application PrngrammingInterface显示文摘 | Shiddiqi A M Pratama H Ciptaningtyas H T | | 0，，03： | 1 |
| 7 | A Video Streaming Application Using Mobile Media Application Programming Interface 显示文摘 | Shiddiqi A M Pratama H Ciptaningtyas H T | 2010 | Telkomnika2010，8，3： | 1 |
| 8 | Roquin-2 Shares Functions with Its Paralog Roquin-1 in the Repression of mRNAs Controlling T Follicular Helper Cells and Systemic Inflammation显示文摘 | Alvin Pratama Roybel R. Ramiscal Diego G. Silva Souvik K. Das Vicki Athanasopoulos Jessica Fitch Natalia K. Botelho Pheh-Ping Chang Xin Hu Jennifer J. Hogan Paula Ma?a David Bernal Heinrich Korner Di Yu Christopher C. Goodnow Matthew C. Cook Carola G. Vin | 2013 | Immunity2013，，4： | 1 |
| 9 | Treatment of low do- ses curcumin could modulate Thl7/Treg balance specifically on CD4+ T cell cultures of systemic lupus erythematosus patients 显示文摘 | Handono K Pratama MZ Endharti AT | 2015 | Cent Eur J Immunol2015，40，4： | 1 |
| 10 | Room temperature self-healing thermoset based on the Dials-Alder reaction 显示文摘 | Pratama P A Sharifi M Peterson A M | 2013 | ACS Appl Mater Interfaces2013，5，12： | 1 |
| 11 | Modeling migration of Cs-137 in sewer system of fukushima city u- sing model for radionuclide migration in urban environ- ment and drainage system (MUD)显示文摘 | Pratama M A Yoneda M Yosuke A Y | 2014 | International Jour- nal of Engineering and Technology2014，，6： | 1 |
| 12 | Laparoscopic myomectomy versus open myomectomy in uterine fibroid treatment: A meta-analysis显示文摘Objective:Uterine fibroids are the most commonly occurring benign solid tumors in women,and laparoscopic or open myomectomy constitutes the primary option for treatment.However,both methods are under debate currently in terms of efficacy and safety.In this meta-analysis we assessed the efficacy and safety of the two procedures.Methods:We conducted a comprehensive literature search of PubMed,ScienceDirect,and the Cochrane Library in December 2020.The search terms included“open myomectomy”,“myomectomies”,“laparoscopic”,and“uterine fibroids”.We then selected the randomized control trials published from 1996 to 2019 and compared laparoscopic and open myomectomies.Results:We included 10 studies of 449 patients who underwent laparoscopic myomectomy and 449 patients who underwent open myomectomy.The data revealed that laparoscopic myomectomy was associated with reduced blood loss(MD=-34.43;95%CI,-34.92 to-33.94;p<0.001),an attenuated decline in hemoglobin(MD=-1.04;95%CI,-1.14 to -0.93;p<0.001),less post-operative pain at 24 h(MD=-0.51;95%CI,-0.83 to -0.19;p=0.002),and fewer overall complications(OR=0.42;95%CI,0.24 to 0.71;p=0.001)relative to open myomectomy;but the former possessed a longer operative time(MD=12.96;95%CI,9.94 to 15.97;p<0.001).There were no significant differences in pregnancy rate(OR=1.39;95%CI,0.72 to 2.68;p=0.33)or recurrence rate of postoperative uterine fibroids(OR=1.15;95%CI,0.60 to 2.18;p=0.67)between the two groups.Conclusion:Laparoscopic myomectomy displayed superior results compared to open myomectomy,although the former involved a longer operating time. | Probo Yudha Pratama Putra Arlinda Silva Prameswari Mochammad Ma'roef Aida Musyarrofah Halida Nelasari | 2021 | Laparoscopic, Endoscopic and Robotic Surgery2021，4，3： | 1 |
| 13 | Control of TFH cell numbers: why and how? 显示文摘 | Pratama A Vinnesa C G | 2014 | Immunol Cell Biol2014，92，1： | 1 |
| 14 | Changes in culture expanded human amniotic epithelial cells:implications for potential therapeutic applications显示文摘 | Pratama G Vaghjiani V Tee JY | 2011 | PLoS One2011，6，26： | 1 |
| 15 | Effects of Varieties and Cooking Methods on Physical and Chemical Characteristics of Cooked Rice显示文摘To analyze the effect of different lowland rice varieties and different cooking methods on physical and chemical characteristics of cooked rice. A factorial randomized block design with two factors was used and each combination of the factors was repeated three times. The first factor was rice variety(Ciherang and Ciliwung) and the second factor was the cooking method(stovetop, boiling and steaming, and rice cooker). Results showed that Ciherang and Ciliwung varieties were classified into slender grain rice type with yellowred color. The amylose content of Ciherang was classified as moderate, while the amylose content of Ciliwung classified as low. The most abundant amino acid contained in Ciherang and Ciliwung varieties was glutamic acid. Statistical analysis showed that cooking method had significant effects on texture, lightness, chroma, hue and moisture content of cooked rice. Rice cooked with liwet method had the lowest texture value, lowest lightness value, highest chroma value, and highest moisture content. | Merynda Indriyani SYAFUTRI Filli PRATAMA Friska SYAIFUL Achmad FAIZAL | 2016 | Rice science2016，23，5： | 1 |
| 16 | Changes in culture expanded human amniotic epithelial cells: implications for potential therapeutic applications 显示文摘 | Pratama G Vaghjiani V Tee JY | 2011 | PLoS One2011，6，26： | 1 |
| 17 | 一条专用车道双向运营BRT/轻轨的可行性显示文摘为有效满足BRT或轻轨系统的运行需求,提出在带有固定左转车道的繁忙通勤走廊中央设置一条BRT或轻轨专用车道用于双向运营的概念。由此产生了车辆相交问题,其相交空间设置于由左转车道产生的未利用或未被充分利用的道路中央隔离带。提供了公交车站和相交空间的概念设计可选方案和几何布局示意图,并考虑运行速度、发车间隔、相邻相交空间的距离及相交空间数量等条件,分析系统性能。为确保具有实用性,研究了系统在现有交通走廊上的可实施性。由于该系统具有利于TOD发展的潜力,也可作为未来发展两条专用车道系统的中间步骤。 | H-S Jacob Tsao Wenbin Wei Agus Pratama 范烺 高海欣 | 2010 | 城市交通2010，8，2： | 1 |
| 18 | Roquin-2 shares func- tions with its paralog Roquin-1 in the repression of mRNAs con- trolling T follicular helper cells and systemic inflammation 显示文摘 | Pratama A Ramiscal RR Silva DG | 2013 | Immunity2013，38，4： | 1 |
| 19 | Knowledge, attitudes, and practices regarding Covid-19 and their relationship with Covid-19 booster vaccination status among women with infertility显示文摘Objective:To elucidate the relationship among knowledge,attitudes,and practices regarding Covid-19 and their relationship with booster vaccination status among women with infertility.Methods:This questionnaire-based cross-sectional study was performed online and offline among women with infertility who visited an infertility clinic in Jakarta,Indonesia.We assessed the patient’s knowledge,attitudes,and practices regarding Covid-19 and their relationship with booster vaccination status and sociodemographic profile.Results:A total of 178 subjects participated in this study,and most participants(92.6%)had received booster Covid-19 vaccines.From the questionnaire,74.2%had good knowledge,and 99.4%had good attitudes regarding Covid-19;however,only 57.9%of patients had good practices.A weak positive correlation existed between knowledge and attitudes(r=0.11,P=0.13)and a moderate negative correlation between attitudes and practices(r=-0.44,P=0.56).Participants’knowledge about vaccines and infertility was correlated with booster vaccination status(P=0.04).Academic background(P=0.01)and attitudes(P=0.01)were also correlated with booster vaccination status.The significant determinants of hesitance of receiving Covid-19 booster vaccines were high school education or below(OR=0.08,95%CI 0.02-0.36)and poor practices(OR=0.21,95%CI 0.05-0.95).Conclusions:The majority of the participants had received the Covid-19 booster vaccine and had good knowledge and attitudes but poor practices regarding Covid-19.Most participants had poor knowledge about the relationship between infertility and the Covid-19 vaccine.The general population should be more informed and reminded about practices to prevent Covid-19 and the relationship between vaccination and fertility to increase the number of people who receive Covid-19 booster vaccines. | Gita Pratama Mila Maidarti Kanadi Sumapradja Achmad Kemal Harzif Natasha Talya Kevin Ezekia Irfan Arieqal Hatta Ampri | 2024 | Asian pacific Journal of Reproduction2024，13，2： | 0 |
| 20 | Cracking of a Used Lubricant Oil Using NiMo/MCM-41 and the Mixture of Ni/MCM-41 and H-MCM-41 Catalysts显示文摘 | Falah lip Izul Armunanto Ria Pratama Aristo Tyas | 2013 | Journal of Chemistry and Chemical Engineering2013，7，2： | 0 |
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