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| 1 | Enhanced myocardial fluorodeoxyglucose uptake following Adriamycin-based therapy: Evidence of early chemotherapeutic cardiotoxicity?显示文摘AIM: To analyze changes in myocardial glucose metabolism using fluorodeoxyglucose (FDG)-positron emission tomography (PET) in patients treated with adriamycin and to investigate the clinical significance of these changes.METHODS: Considering that FDG-PET scanning has the ability to show changes in glucose metabolism in the myocardium, we retrospectively analyzed the FDGPET studies of 18 lymphoma patients treated with adriamycin-based chemotherapy in both the preand posttherapy setting. Cardiac contractile parameters such as left ventricular ejection fraction were not available for correlation in all patients due to the short duration and the level of cumulative dose administered in these patients during the time of the follow-up FDG-PET study. The change in myocardial glucose utilization was estimated by change in standard uptake values (SUV) in the myocardium.RESULTS: We observed a significant change in SUVmean values in the myocardium (defined as more than change in cardiac SUVmean between pre-and post-chemotherapy PET) in 1 patients, whereas 6 patients did not show any significant cardiac FDG uptake in both preand post-therapy PET scans. Patients were divided into three groups based on the changes observed in myocardial tracer uptake on the followup 18 F-FDG-PET study. Group A (n = 8): showed an increase in cardiac 18 F-FDG uptake in the post-therapy scan compared to the baseline scan carried out prior to starting adriamycin-based chemotherapy. Group B (n = 6): showed no significant cardiac 18 F-FDG uptake in post-therapy and baseline PET scans, and group C (n = 4): showed a fall in cardiac 18 F-FDG uptake in the posttherapy scan compared to the baseline scan. Mean cumulative adriamycin dose (in mg/m 2 ) received during the time of the follow-up FDG-PET study was 256. 25, 250 and 137.5, respectively.CONCLUSION: Our study shows three different trends in the change in myocardial glucose metabolism in patients undergoing adriamycin-based chemotherapy. A further prospective study with prolonged follow-up of ventricular function is warranted to explore the significance of enhanced FDG uptake as a marker of early identification of adriamycin-induced cardiotoxicity. | Chaitanya Borde Purushottam Kand Sandip Basu | 2012 | World Journal of Radiology2012，4，5： | 9 |
| 2 | 变时滞不确定Lurie系统的时滞分布依赖鲁棒稳定性分析(英文)显示文摘In this paper, the problem of robust absolute stability of Lurie system with probabilistic time-varying delay and normbounded parametric uncertainty is considered. The time delay variation range is divided into two sub-intervals. By considering the probability distribution of the time-varying delay between the two sub-intervals and the knowledge of the delay variation range, a novel linear matrix inequalities (LMIs) based stability condition is derived by defining a Lyapunov Krasovskii functional. It is illustrated with the help of numerical examples that the derived stability criteria can lead to less conservative results as compared to the results obtained by the traditional method of using the delay variation range information only. | MUKHIJA Pankaj KAR Indra Narayan BHATT Rajendra Kumar Purushottam | 2012 | 自动化学报2012，38，7： | 2 |
| 3 | Microstrip fractal patch antenna for multiband communication显示文摘 | HARA PRASAD R V PURUSHOTTAM Y MISRA V C | 2000 | Electronics Letter2000，36，14： | 2 |
| 4 | Comparison of snow water equivalent retrieved from SSM/I passive microwave data using artificial neural network, projection pursuit and non linear regres-sions显示文摘 | Gan ThianYew Kalinga O Purushottam Singh | 2009 | Remote Sensing of Environment2009，113，5： | 1 |
| 5 | Impact of FDG-PET and -PET/CT imaging in the clinical decision-making of ovarian carcinoma: an evidence-based approach显示文摘 | Vandana Kumar Dhingra Purushottam Kand Sandip Basu | 2012 | Women’s Health2012，，： | 1 |
| 6 | Decadal trends in precipitable water vapor over the Indus River Basin using ERA5 reanalysis data显示文摘Precipitable Water Vapor(PWV)constitutes a pivotal parameter within the domains of atmospheric science,and remote sensing due to its profound influence on Earth’s climate dynamics and weather patterns.It exerts a significant impact on atmospheric stability absorption and emission of radiation,thus engendering alterations in the Earth’s radiative equilibrium.As such,precise quantification of PWV holds the potential to enhance weather prognostication and fortify preparedness against severe meteorological phenomena.This study aimed to elucidate the spatial and temporal changes in seasonal and annual PWV across the Indus River Basin and its sub-basins using ERA5 reanalysis datasets.The present study used ERA5 PWV(entire atmospheric column),air temperature at 2 m(t2m)and 500 hPa(T_500hPa),evapotranspiration,and total cloud cover data from 1960 to 2021.Theil Sen slope estimator and Mann-Kendall test were used for trend analysis.Correlation and multiple regression methods were used to understand the association of PWV with other factors.The findings have unveiled the highest increase in mean PWV during the monsoon(0.40 mm/decade),followed by premonsoon(0.37 mm/decade),post-monsoon(0.27 mm/decade),and winter(0.19 mm/decade)throughout the study period.Additionally,the mean PWV exhibited the most pronounced positive trend in the sub-basin Lower Indus(LI),followed by Panjnad(P),Kabul(K),and Upper Indus(UI)across all seasons,except winter.Annual PWV has also risen in the Indus basin and its sub-basins over the last six decades.PWV exhibits a consistent upward trend up to an elevation of 3500 m within the basin which is most pronounced during the monsoon season,followed by the pre-monsoon.The escalating PWV within the basin is reasonably ascribed to increasing air temperatures,augmented evapotranspiration,and heightened cloud cover.These findings hold potential utility for pertinent authorities engaged in water resource management and planning. | Seema RANI Jyotsna SINGH Subhash SINGH Purushottam TIWARI Suraj MAL | 2023 | Journal of Mountain Science2023，20，10： | 1 |
| 7 | Evolutionary a- nalysis of PHLPPl gene in humans and non - human primates 显示文摘 | Anbazhagan P Purushottam M Kumar HB | 2008 | Bioinformation2008，2，10： | 1 |
| 8 | An investigation of reference price segments 显示文摘 | Mazumdar Tridib and Papatla Purushottam | 2000 | Journal of Marketing Research2000，37，2000： | 1 |
| 9 | spinocerebellar ataxias types 1,2 and 3:age adjusted clinical severity of disease at presentation correlates with size of CAG repeat lengths显示文摘 | Netravathi M Pal PK Purushottam M et a | 2009 | J Neurol Sci2009，277，12： | 1 |
| 10 | Microstrip Fractal Patch Antenna for Multiband Communication 显示文摘 | Hara Prasad R V Purushottam Y Misra V C | 2006 | Electronics Letters2006，36，14： | 1 |
| 11 | Spinocerebellar ataxiastypes 1,2 and 3:age adjusted clinical severity of disease at presentation correlates with size of CAG repeat lengths显示文摘 | Netravathi M Pal PK Purushottam M | | 0，，1： | 1 |
| 12 | 乳腺癌切除术后乳房再造中胸肌下筋膜蒂皮瓣在覆盖扩张器中的应用:一项新技术显示文摘目的 在扩张器辅助的乳房再造术中,对假体表面提供足够的组织覆盖是非常必要的,在避免并发症方面有很大功效.笔者先前报道过前锯肌筋膜在此方面中的应用;然而,当前锯肌筋膜不可用或组织量不足时,胸肌下筋膜可以替代.本研究描述胸肌下筋膜的解剖、切取胸肌下筋膜的外科学技术以及如何在前锯肌筋膜和胸肌下筋膜进行选择的原则.探讨胸肌下筋膜在扩张器辅助的乳房再造术中的临床应用及作用.方法 本组13例患者(17侧乳房).经审查委员会认可(知情同意),对所有病例进行回顾性统计分析及手术相关因素分析.记录包膜挛缩、血清肿、血肿、切口裂开及感染等并发症发生情况.对10侧胸部尸体标本进行解剖学研究.对每具标本的胸肌下筋膜进行解剖分离,并测定其长度和宽度.结果 所有患者平均随访589d(115~960d),1例(1侧乳房)出现血清肿,1例(1侧乳房)出现切口感染,1例(1侧乳房)切口出现小范围裂开.尸体标本解剖研究显示,胸肌下筋膜长度的均数±方差(mean±SD)为(148.0±26.6)mm,宽度为(83.0±32.1)mm.结论 在扩张器辅助的乳房再造术中,胸肌下筋膜瓣可对假体的外侧、下方提供覆盖(包被)支持,是一个创新的、安全的方法.胸肌下筋膜的切取及应用不会对术后临床效果造成不良反应. | Michel Saint-Cyr Purushottam Nagarkar Corrine Wong Hema Thakar Phillip Dauwe Rod J. Rohrich 魏峰(译) 高景恒(译) 张晨(译) | 2011 | 中国美容整形外科杂志2011，22，3： | 1 |
| 13 | The role of complement in ocular pathology显示文摘 | Nalini S. Bora Purushottam Jha Puran S. Bora | 2008 | Seminars in Immunopathology2008，，2： | 1 |
| 14 | The role of complement system in ocular diseases including uveitis and macular degeneration显示文摘 | Purushottam Jha Puran S. Bora Nalini S. Bora | 2007 | Molecular Immunology2007，，16： | 1 |
| 15 | Microstrip fractal patch for multiband communication 显示文摘 | Prasad R V H Purushottam Y Misra V C | 2000 | Electron Lett2000，36，14： | 1 |
| 16 | Giant Cell Tumor of Tendon Sheath: Largest Single Series in Children显示文摘 | Purushottam A. Gholve Harish S. Hosalkar Portia A. Kreiger John P. Dormans | 2007 | Journal of Pediatric Orthopaedics2007，，1： | 1 |
| 17 | Predictors for sec- ondary procedures in walking DDH显示文摘 | Purushottam A Gholve MD Johnm Fynn | 2012 | J Pediatr Orthop2012，32，： | 1 |
| 18 | Electrochemical enhancement of LiFePO4 as a cathode material by incorporating Cu flakes for lithium ion rechargeable battery显示文摘 | Jungbae Lee Purushottam Kumar Brij M Moudgil | 2013 | Solid State Ionics2013，231，： | 1 |
| 19 | SpinocerebeIlar ataxias types 1,2 and 3:age adjusted clinical severity of disease at presentation correlates with size of CAG repeat lengths显示文摘 | Netravathi M Pal PK Purushottam M | | 0，，： | 1 |
| 20 | Identifying Locations for Targeted Advertising on the Internet 显示文摘 | Amit Bhatnagar Purushottam Papatla | 2001 | Interna- tional Journal of Electronic Commerce2001，，53： | 1 |
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