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	题名	作者	年代	出处	被引量
1	Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation显示文摘AIM To explore the expression of perform andgranzyme B genes mRNA to judge the effect ofimmunosuppression in acute rejection of livertransplantation.METHODS The expression of perform andgranzyme B genes mRNA was examined byreverse transcriptase-polymerase chain reaction(RT--PCR) in hamster to rat liver grafts under theimmunosuppression of cyclosporine or/andsplenectomy. Histological findings were studiedcomparatively.RESULTS Cyclosporine could obviouslydecrease the cellular infiltration, and completelyrepress the expression of mRNA for perform andgranzyme B, but could not change severehepatocyte necrosis and hemorrhage.SPlenectomy could significantly lightenhepatocyte necrosis, and completely eliminatehemorrhage, but not atfect the cellularinfiltration and the expression of perform andgranzyme B genes mRNA. Cyclosporine orsplenectomy alone could not prolong theSurvival time, however, their combination couldcompletely repress the rejection of liver grafts.The survival time of animals were significantlyprolonged (37.1 days ). The architecture ofhepatic lobules was preserved. There was slightcellular infiltration in the portal tracts and noexpression of perform and granzyme B genesmRNA could be seen in three weeks aftertransplantation.CONCLUSION Perform and granzyme B genesare valuable in judging the effect ofimmunosuppression in liver transplantation.	Zhang SG Wu MC Tan JW Chen H Yang JM Qian QJ	1999	World Journal of Gastroenterology1999，5，3：	15
2	Cytogenetic and genetic pathways in therapy - related acute myeloid leukemia 显示文摘	Qian z Joslin JM Tennant TR	2010	Chem Biol Interact2010，184，12：	1
3	Determination of antisense phosphorothioate oligonucleotides and catabolites in biological fluids and tissue extracts using anion-exchange high-performance liquid chromatography and capillary gel electrophoresis显示文摘	Chen SH Qian MX Brennan JM	1997	Chromatogr B1997，692，1：	1
4	Upregulation of urea transporter UT- A2 and water channels AQP2 and AQP3 in mice lacking urea transporter UT - B 显示文摘	Klein JD Sands JM Qian L	2004	J Am Soc Nephrol2004，15，5：	1
5	Imprinted tumor suppressor gene ARHI induces apoptosis correlated with changes in DNA methylation in pancreatic cancer cells 显示文摘	Yang H Lu XQ Qian JM	2010	Molecular Medicine Reports2010，11，3：	1
6	A Fibro-osseous lesions of the cen- tral nervous system: report of four cases and literature review 显示文摘	Qian J Rubio A Powers JM	1999	Am J Surg Pathol1999，23，10：	1
7	FAS mRNA editing in Human Systemic Lupus Erythematosus 显示文摘	Wu JM Xie FL Qian K	2011	Hum Mutat2011，32，11：	1
8	Inhibition of matrix metalloproteinase- 9 attenuates acute small-for-size liver graft injury in rats 显示文摘	Ma ZY Qian JM Rui XH	2010	Am J Transplant2010，10，4：	1
9	Stable antibody expression at therapeutic levels using the 2A peptide显示文摘	Fang JM Qian JJ Yi SL	2005	Nat Biotechnol2005，23，5：	1
10	Nitric oxide accumulation in the nonventilated nasal cavity显示文摘	Chatkin JM Qian W McClean PA	1999	Archives of Otolarynglogy-Head & Neck Surgery1999，125，6：	1
11	Nitric oxide in the nasal airway: a new dimetlsion in otorhinolaryngology显示文摘	Djupesland PG Chatkin JM Qian W	2001	Am J Otolaryngol2001，22，1：	1
12	Identification of a new metabolite of astilbin, Y-O-methylastilbin, and its ac- tivity against contact dermatitis 显示文摘	Guo JM Qian F Li JX	2007	Clin Chem2007，53，3：	1
13	Aerodynamic in- fluences on nasal nitric oxide output measurements 显示文摘	Djupesland PG Chatkin JM Qian W	1999	Acta Otolaryngol1999，119，4：	1
14	Advances and chal enges in liquid chromatography-mass spectrometry-based proteomics profiling for clinical applications显示文摘	Qian WJ Jacobs JM Liu T		0，，10：	1
15	Effects of IL-1β on the proliferation and apoptosis of gastric epithelial cells and acid secretion from isolated rabbit parietal cells 显示文摘	Guo T Qian JM Zhao YQ	2013	Mol Med Rep2013，7，1：	1
16	Reduction/pH dual-sensitive PEGylated hyaluronan nanoparticles for targeted doxorubicin delivery显示文摘	XU MH QIAN JM SUO AL	2013	Carbohyd Polym2013，98，1：	1
17	Overexpression of PAI-1 preventsthe development of abdominal aortic aneurysm in mice 显示文摘	Qian HS Gu JM Liu P	2008	GeneTher2008，15，3：	1
18	A reduction-dissociable PEG-b-PGAH-b-PEI triblock copolymer as a vehicle for targeted co-delivery of doxorubicin and P-gp siRNA显示文摘	XU MH QIAN JM SUO AL	2015	Polym Chem2015，6，13：	1
19	Preparation of porous SiC ceramic with a woodlike microstructure by sol-gel and carbothermal reduction processing显示文摘	QIAN JM WANG JP QIAO GJ	2004	Journal of the European Ceramic Society2004，24，1011：	1
20	Evaluating the role of imaging methods in the diagnosis of chronic pancreatitis显示文摘	Guo T Qian JM Yang Am	2003	Chinese J Diges Dis2003，4，：	1

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