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| 1 | Identification of a novel coronavirus causing severe pneumonia in human:a descriptive study显示文摘Background:Human infections with zoonotic coronaviruses(CoVs),including severe acute respiratory syndrome(SARS)-CoV and Middle East respiratory syndrome(MERS)-CoV,have raised great public health concern globally.Here,we report a novel batorigin CoV causing severe and fatal pneumonia in humans.Methods:We collected clinical data and bronchoalveolar lavage(BAL)specimens from five patients with severe pneumonia from Wuhan Jinyintan Hospital,Hubei province,China.Nucleic acids of the BAL were extracted and subjected to next-generation sequencing.Virus isolation was carried out,and maximum-likelihood phylogenetic trees were constructed.Results:Five patients hospitalized from December 18 to December 29,2019 presented with fever,cough,and dyspnea accompanied by complications of acute respiratory distress syndrome.Chest radiography revealed diffuse opacities and consolidation.One of these patients died.Sequence results revealed the presence of a previously unknownβ-CoV strain in all five patients,with 99.8%to 99.9%nucleotide identities among the isolates.These isolates showed 79.0%nucleotide identity with the sequence of SARS-CoV(GenBank NC_004718)and 51.8%identity with the sequence of MERS-CoV(GenBank NC_019843).The virus is phylogenetically closest to a bat SARS-like CoV(SL-ZC45,GenBank MG772933)with 87.6%to 87.7%nucleotide identity,but is in a separate clade.Moreover,these viruses have a single intact open reading frame gene 8,as a further indicator of bat-origin CoVs.However,the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV,indicating that these viruses might use the same receptor.Conclusion:A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans. | Li-Li Ren Ye-Ming Wang Zhi-Qiang Wu Zi-Chun Xiang Li Guo Teng Xu Yong-Zhong Jiang Yan Xiong Yong-Jun Li Xing-Wang Li Hui Li Guo-Hui Fan Xiao-Ying Gu Yan Xiao Hong Gao Jiu-Yang Xu Fan Yang Xin-Ming Wang Chao Wu Lan Chen Yi-Wei Liu Bo Liu Jian Yang Xiao-Rui Wang Jie Dong Li Li Chao-Lin Huang Jian-Ping Zhao Yi Hu Zhen-Shun Cheng Un-Lin Liu Zhao-Hui Qian Chuan Qin Qi Jin Bin Cao Jian-Wei Wang | 2020 | Chinese Medical Journal2020，，9： | 99 |
| 2 | A wireless solution for greenhouse monitoring and control system based on ZigBee technology显示文摘With the rapid development of wireless technologies, it is possible for Chinese greenhouses to be equipped with wireless sensor networks due to their low-cost, simplicity and mobility. In the current study, we compared the advantages of ZigBee with other two similar wireless networking protocols, Wi-Fi and Bluetooth, and proposed a wireless solution for green- house monitoring and control system based on ZigBee technology. As an explorative application of ZigBee technology in Chinese greenhouse, it may promote Chinese protected agriculture. | ZHANG Qian YANG Xiang-long ZHOU Yi-ming WANG Li-ren GUO Xi-shan | 2007 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2007，8，10： | 60 |
| 3 | Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis显示文摘The heat shock transcription factors (HSFs) are the major heat shock factors regulating the heat stress response. They participate in regulating the expression of heat shock proteins (HSPs), which are critical in the protection against stress damage and many other important biological processes. Study of the HSF gene family is important for understanding the mechanism by which plants respond to stress. The completed genome sequences of rice (Oryza sativa) and Arabidopsis (Arabidopsis thaliana) constitute a valuable resource for comparative genomic analysis, as they are representatives of the two major evolutionary lineages within the angiosperms: the monocotyledons and the dicotyledons. The identification of phylogenetic relationships among HSF proteins in these species is a fundamental step to unravel the functionality of new and yet uncharacterized genes belonging to this family.In this study, the full complement of HSF genes in rice and Arabidopsis has probably been identified through the genome-wide scan. Phylogenetic analyses resulted in the identification of three major clusters of orthologous genes that contain members belonging to both species, which must have been represented in their common ancestor before the taxonomic splitting of the angiosperms. Further analysis of the phylogenetic tree reveals a possible dicot specific gene group. We also identified nine pairs of paralogs, as evidence for studies on the evolution history of rice HSF family and rice genome evolution. Expression data analysis indicates that HSF proteins are widely expressed in plants. These results provide a solid base for future functional genomic studies of the HSF gene family in rice and Arabidopsis. | Jingkang Guo Jian Wu Qian Ji Chao Wang Lei Luo Yi Yuan Yonghua Wang Jian Wang | 2008 | Journal of Genetics and Genomics2008，35，2： | 52 |
| 4 | A Rare Allele of GS2 Enhances Grain Size anc Grain Yield in Rice显示文摘谷物尺寸决定谷物重量并且影响谷物质量。调整谷物尺寸的几主要量的特点 loci (QTL ) 被克隆;然而,我们调整米饭谷物的尺寸的内在的机制的理解仍然保持碎片。这里,我们报导克隆和主导的 QTL 的描述,染色体 2 上的谷物尺寸(GS2 ) 编码调整生长的因素 4,一个 transcriptional 管理者。GS2 本地化到原子核并且可以充当抄写使活跃之物。影响 microRNA 的有约束力的地点的 GS2 的一个稀罕变化, OsmiR396c,原因提高了 GS2/OsGRF4 的表示。GS2 表示的增加导致更大的房间和房间的增加的数字,它因此提高谷物重量和产量。进米饭栽培变种的 GS2/OsGRF4 的这稀罕等位基因的介绍能显著地提高谷物重量和增加谷物产量,用在引起产量很高的米饭变化的可能的应用。 | Jiang Hu Yuexing Wang Yunxia Fang Longjun Zeng Jie Xu Haiping Yu Zhenyuan Shi Jiangjie Pan Dong Zhang Shujing Kang Li Zhu Guojun Dong Longbiao Guo Dali Zeng Guangheng Zhang Lihong Xie Guosheng Xiong Jiayang Li Qian Qian | 2015 | Molecular Plant2015，8，10： | 57 |
| 5 | Development and Prospect of SiC Power Devices in Power Grid显示文摘碳化硅作为一种宽禁带材料,具有高击穿场强、高饱和电子漂移速率、高热导率等优点,可以实现高压、大功率、高频、高温应用的新型功率半导体器件。该文对碳化硅功率半导体器件的最新发展进行回顾,包括碳化硅功率二极管、MOSFET、IGBT和晶闸管,对其在电力系统的应用现状与前景进行展望。高压大容量碳化硅功率半导体器件的迅速发展,将对电力系统的发展带来深远的影响。 | SHENG Kuang GUO Qing ZHANG Junming QIAN Zhaoming | 2012 | 中国电机工程学报2012，32，30： | 42 |
| 6 | Breeding high-yield superior quality hybrid super rice by rational design显示文摘The challenge of meeting the increasing demand for worldwide rice production has driven a sustained quest for advances in rice breeding for yield. Two breakthroughs that led to quantum leaps in productivity last century were the introduction of semidwarf varieties and of hybrid rice. Subsequent gains in yield have been incremental. The next major leap in rice breeding is now upon us through the application of rational design to create defined ideotypes. The exploitation of wide-cross compatibility and intersubspecific heterosis,combined with rapid genome sequencing and the molecular identification of genes for major yield and quality traits have now unlocked the potential for rational design. | Qian Qian Longbiao Guo Steven M.Smith Jiayang Li | 2016 | National Science Review2016，3，3： | 48 |
| 7 | Double contrast-enhanced two-dimensional and three-dimensional ultrasonography for evaluation of gastric lesions显示文摘AIM:To investigate the value of two-dimensional(2D) and three-dimensional(3D) double contrast-enhanced ultrasonography(DCUS) imaging for evaluation of gastric lesions.METHODS:2D and 3D DCUS imaging with both oral and intravenous administrations of contrast agents was used to assess gastroscopiclly-confirmed gastric lesions in 46 patients with benign and malignant diseases.Initially,liquid-based ultrasound contrast agent(Xinzhang) was given orally at dose of 500-600 mL for conventional ultrasound examination of the gastric lesions,and then a microbubble-based contrast agent(SonoVue) was injected intravenously at dose of 1.2-2.4 mL in bolus fashion to assess the perfusion pattern of the lesions using contrast imaging modes.The parameters derived from time-intensity curves including the arrival time(AT),time to peak(TTP),peak intensity(PI) and enhanced intensity(EI) were measured on the 2D DCUS imaging.3D DCUS of the lesions was acquired to demonstrate the value of this imaging mode.RESULTS:There were 22 cases with benign lesions including chronic gastritis(n = 5),gastric ulcer(n = 9),gastric polyps(n = 3),gastric stromal tumors(n = 5),and 24 cases with malignant lesions including gastric cancer(n = 20),gastric cardia carcinoma(n = 3) and post-operative recurrent gastric cancer(n = 1) in the study.The oral contrast-enhanced ultrasonography(CEUS) imaging of the stomach clearly demonstrated the anatomy of the stomach and morphologic features of gastric lesions.With optimal scanning window and imaging display under oral CEUS,intravenous CEUS clearly showed the perfusion of gastric lesions with various characteristic manifestations.Both 2D and 3D DCUS images clearly demonstrated normal gastric wall as a three-layer structure,from the inside out,hyperechoic mucosa,hypoechoic muscularis and hyperechoic serosa,respectively.There were statistical significant differences of AT(8.68 ± 2.06 vs 10.43 ± 2.75,P = 0.017),PI(34.64 ± 6.63 vs 29.58 ± 8.22,P = 0.023) and EI(29.72 ± 6.69 vs 22.66 ± 7.01,P = 0.001) between malignant lesions and normal gastric wall.However,no differences of AT,PI and EI between benign lesions and normal gastric wall tissue were found.3D DCUS could intuitively display morphological features and vascularities of the lesions with multiplanar and volume views.3D DCUS imaging provided comprehensive information complementary to 2D imaging.The crater or wellhead appearances and feeding vessels as well as distorted nourishing vasculature of gastric carcinoma were better seen with 3D imaging than 2D imaging.CONCLUSION:DCUS imaging can simultaneously display the anatomic and perfusion features of gastric lesions.3D DCUS can provide additional information to 2D DCUS for evaluation of gastric lesions. | Hong Shi Xiu-Hua Yu Xin-Zhang Guo Yuan Guo Hong Zhang Bin Qian Zhang-Rui Wei Li Li Xian-Chen Wang Zi-Xiang Kong | 2012 | World Journal of Gastroenterology2012，18，31： | 36 |
| 8 | Linking atmospheric pollution to cryospheric change in the Third Pole region: current progress and future prospects显示文摘The Tibetan Plateau and its surroundings are known as the Third Pole(TP). This region is noted for its high rates of glacier melt and the associated hydrological shifts that affect water supplies in Asia. Atmospheric pollutants contribute to climatic and cryospheric changes through their effects on solar radiation and the albedos of snow and ice surfaces; moreover, the behavior and fates within the cryosphere and environmental impacts of environmental pollutants are topics of increasing concern. In this review, we introduce a coordinated monitoring and research framework and network to link atmospheric pollution and cryospheric changes(APCC) within the TP region. We then provide an up-to-date summary of progress and achievements related to the APCC research framework, including aspects of atmospheric pollution’s composition and concentration, spatial and temporal variations, trans-boundary transport pathways and mechanisms, and effects on the warming of atmosphere and changing in Indian monsoon, as well as melting of glacier and snow cover. We highlight that exogenous air pollutants can enter into the TP’s environments and cause great impacts on regional climatic and environmental changes. At last, we propose future research priorities and map out an extended program at the global scale. The ongoing monitoring activities and research facilitate comprehensive studies of atmosphere–cryosphere interactions, represent one of China’s key research expeditions to the TP and the polar regions and contribute to the global perspective of earth system science. | Shichang Kang Qianggong Zhang Yun Qian Zhenming Ji Chaoliu Li Zhiyuan Cong Yulan Zhang Junming Guo Wentao Du Jie Huang Qinglong You Arnico K.Panday Maheswar Rupakheti Deliang Chen Orjan Gustafsson Mark H.Thiemens Dahe Qin | 2019 | National Science Review2019，6，4： | 35 |
| 9 | Prognostic significance of VEGF-C expression in correlation with COX-2, lymphatic microvessel density, and clinicopathologic characteristics in human non-small cell lung cancer显示文摘因为高发生和高死亡,肺癌症是在中国的最致命的癌症之一。Cyclooxygenase-2 (COX-2 ) 和容器 endothelial 生长因素 C (VEGF-C ) 被发现在恶意的肿瘤的 lymphangiogenesis 起一个重要作用。在这研究,我们调查了淋巴的 microvessel 密度(LMVD ) 是否与在非小的房间肺癌症(NSCLC ) 的预后有关是 COX-2 和 VEGF-C 的病人,和表情以便在 NSCLC lymphangiogenesis 决定 COX-2 和 VEGF-C 的可能的角色。嵌入的织物 NSCLC 取样的 65 修理福尔马林的石蜡被染色的 immunohistochemical 为 COX-2 和 VEGF-C 评估。估计肿瘤 lymphangiogenesis, LMVD 被 immunohistochemical 染色 VEGFR-3 polyclonal 决定抗体。在 COX-2 和 VEGF-C 表示, LMVD,和 clinicopathologic 参数之中的关系被分析。在 65 件样品之中,高 LMVD 显著地与淋巴节点转移和差的幸存被联系。Multivariate 幸存分析证明那 LMVD 价值和淋巴节点转移是独立预示的因素。COX-2 和 VEGF-C 的表示水平比邻近的纸巾的那些显著地高。在 NSCLC 的 COX-2 和 VEGF-C 表情显著地与淋巴节点转移,然而并非与耐心的性,年龄,肿瘤尺寸,或肿瘤相关,节点,转移分类舞台。COX-2- 或 VEGF-C-positive 肿瘤的吝啬的 LMVD 价值比 COX-2- 或 VEGF-C-negative 肿瘤的高。重要关联在 COX-2 和 VEGF-C 的表情之间被发现。这研究建议 LMVD 可以是为 NSCLC 病人的重要预示的因素之一。VEGF-C 可能在 COX-2 lymphangiogenic 小径起一个重要作用。COX-2 和 VEGF-C 可以由刺激 lymphangiogenesis 在肿瘤前进起一个重要作用。lymphangiogenesis, COX-2,或 VEGF-C 活动的抑制可以在 NSCLC 的控制有一个重要治疗学的好处。 | Xufeng Guo Yongbing Chen Zhonghua Xu Zhonghen Xu Yongyue Qian Xueyan Yu | 2009 | Acta Biochimica et Biophysica Sinica2009，41，3： | 34 |
| 10 | Rice leaf inclination2, a VIN3-1ike protein, regulates leaf angle through modulating cell division of the collar显示文摘作为一个重要农学的特点,叶子的倾斜为庄稼建筑学和谷物收益是关键的。理解控制米饭叶角度的分子的机制,一米饭叶 inclination2 (lc2,三等位基因) 异种被识别并且机能上地描绘了。比作野类型的植物, lc2 异种在薄板的近轴的外皮由于增加的细胞分割扩大了叶角度关节。LC2 基因通过位置的克隆被孤立,并且编码开花结实促进法感觉迟钝的 3-like 蛋白质。LC2 的互补表示颠倒了 lc2 植物的扩大的叶角度,证实它在控制叶倾斜的角色。LC2 主要在叶开发期间在薄板关节被表示,并且特别地,被植物激素 abscisic 酸, gibberellic 酸,植物生长素,和 brassinosteroids 导致。LC2 在原子核是局部性的, LC2 的缺点导致房间分割和荷尔蒙应答的基因的改变的表示,显示在调整叶倾斜和调停的荷尔蒙效果的 LC2 的一个重要角色。 | Shu-Qing Zhao Jiang Hu Long-Biao Guo Qian Qian Hong-Wei Xue | 2010 | Cell Research2010，20，8： | 34 |
| 11 | Correlation of red cell distribution width with the severity of coronary artery disease: a large Chinese cohort study from a single center显示文摘 | MA Feng-lian LI Sha LI Xiao-lin LIU Jun QING Ping GUO Yuan-lin XU Rui-xia ZHU Cheng-gang JIA Yan-jun LIU Geng DONG Qian WU Na-qiong JIANG Li-xin LI Jian-jun | 2013 | Chinese Medical Journal2013，，6： | 32 |
| 12 | Genome-wide Targeted Mutagenesis in Rice Using the CRISPR/Cas9 System显示文摘 | Lu, Yuming Ye, Xiao Guo, Renming Huang, Jing Wang, Wei Tang, Jiuyou Tan, Longtao Zhu, Jian-kang Chu, Chengcai Qian, Yangwen | 2017 | Molecular Plant2017，10，9： | 28 |
| 13 | Weapon target assignment problem satisfying expected damage probabilities based on ant colony algorithm显示文摘A weapon target assignment (WTA) model satisfying expected damage probabilities with an ant colony algorithm is proposed. In order to save armament resource and attack the targets effectively, the strategy of the weapon assignment is that the target with greater threat degree has higher priority to be intercepted. The effect of this WTA model is not maximizing the damage probability but satisfying the whole assignment result. Ant colony algorithm has been successfully used in many fields, especially in combination optimization. The ant colony algorithm for this WTA problem is described by analyzing path selection, pheromone update, and tabu table update. The effectiveness of the model and the algorithm is demonstrated with an example. | Wang Yanxia Qian Longjun Guo Zhi Ma Lifeng | 2008 | Journal of Systems Engineering and Electronics2008，19，5： | 26 |
| 14 | Thermodynamics and kinetics of phase transformation in rare earth–magnesium alloys:A critical review显示文摘Magnesium and its alloys are significant superior metallic materials for structural components in automobile and aerospace industries due to their excellent physicomechanical properties.The Mg–rare earth(RE)systems have attracted great interests because RE additions can improve both the deformability and the strength of Mg alloys through solid solution strengthening and precipitation hardening mechanisms.This paper focuses on the interface stability,together with thermodynamics and kinetics of nucleation and growth of the key phases and matrix phases in Mg–RE alloys.In this paper,the theory and recent advances on Mg–RE alloys,especially for the interface stability,thermodynamics and kinetics of nucleation and growth of the key phases and matrix phases,together with their relationships with micro-structures,and macroscopic properties,are reviewed.By combining the thermodynamics/kinetics integrated simulations with various advanced experimental techniques,“reverse”design of Mg–RE alloys starting from the target service performance is put forward as a kind of scientific paradigm with rational design. | Qun Luo Yanlin Guo Bin Liu Yujun Feng Jieyu Zhang Qian Li Kuochih Chou | 2020 | Journal of Materials Science & Technology2020，44，9： | 26 |
| 15 | Clinical practice guidelines for sentinel lymph node biopsy in patients with early-stage breast cancer: Chinese Society of Breast Surgery (CSBrS) practice guidelines 2021显示文摘Axillary lymph node assessment is one of the important indicators in the clinical pathological staging of breast cancer.Studies have shown that sentinel lymph node biopsy(SLNB)has the advantages of fewer complications and less trauma than conventional axillary lymph node dissection(ALND)/[1] Common mapping methods for SLNB include blue dye,radioisotopes,a combination of blue dye and radioisotopes,and fluorescence imaging. | Jing-Ming Ye Bao-Liang Guo Qian Liu Fei Ma Hong-Jin Liu Qian Wu Ling Xin Yuan-Jia Cheng Hong Zhang Shuang Zhang Xue-Ning Duan Jian-Guo Zhang Yin-Hua Liu | 2021 | Chinese Medical Journal2021，，8： | 26 |
| 16 | Progresses on microwave remote sensing of land surface parameters显示文摘Highly accurate observations at various scales on the land surface are urgently needed for the studies of many areas,such as hydrology,meteorology,and agriculture.With the rapid development of remote sensing techniques,remote sensing has had the capacity of monitoring many factors of the Earth's land surface.Especially,the space-borne microwave remote sensing systems have been widely used in the quantitative monitoring of global snow,soil moisture,and vegetation parameters with their all-weather,all-time observation capabilities and their sensitivities to the characteristics of land surface factors.Based on the electromagnetic theories and microwave radiative transfer equations,researchers have achieved great successes in the microwave remote sensing studies for different sensors in recent years.This article has systematically reviewed the progresses on five research areas including microwave theoretical modeling,microwave inversion on soil moisture,snow,vegetation and land surface temperatures.Through the further enrichment of remote sensing datasets and the development of remote sensing theories and inversion techniques,remote sensing including microwave remote sensing will play a more important role in the studies and applications of the Earth systems. | SHI JianCheng DU Yang DU JinYang JIANG LingMei CHAI LinNa MAO KeBiao XU Peng NI WenJian XIONG Chuan LIU Qiang LIU ChenZhou GUO Peng CUI Qian LI YunQing CHEN Jing WANG AnQi LUO HeJia WANG YinHui | 2012 | Science China Earth Sciences2012，55，7： | 24 |
| 17 | Root microbiota shift in rice correlates with resident time in the field and developmental stage显示文摘Land plants in natural soil form intimate relationships with the diverse root bacterial microbiota. A growing body of evidence shows that these microbes are important for plant growth and health. Root microbiota composition has been widely studied in several model plants and crops; however, little is known about how root microbiota vary throughout the plant's life cycle under field conditions. We performed longitudinal dense sampling in field trials to track the time-series shift of the root microbiota from two representative rice cultivars in two separate locations in China. We found that the rice root microbiota varied dramatically during the vegetative stages and stabilized from the beginning of the reproductive stage, after which the root microbiota underwent relatively minor changes until rice ripening. Notably, both rice genotype and geographical location influenced the patterns of root microbiota shift that occurred during plant growth. The relative abundance of Deltaproteobacteria in roots significantly increased overtime throughout the entire life cycle of rice, while that of Betaproteobacteria, Firmicutes, and Gammaproteobacteria decreased. By a machine learning approach, we identified biomarker taxa and established a model to correlate root microbiota with rice resident time in the field(e.g., Nitrospira accumulated from 5 weeks/tillering in field-grown rice). Our work provides insights into the process of rice root microbiota establishment. | Jingying Zhang Na Zhang Yong-Xin Liu Xiaoning Zhang Bin Hu Yuan Qin Haoran Xu Hui Wang Xiaoxuan Guo Jingmei Qian Wei Wang Pengfan Zhang Tao Jin Chengcai Chu Yang Bai | 2018 | Science China(Life Sciences)2018，61，6： | 24 |
| 18 | Report on Childhood Obesity in China (9): Sugar-sweetened Beverages Consumption and Obesity显示文摘Objective To explore the associations between sugar-sweetened beverage (SSB) consumption and obesity as well as obesity-related cardiometabolic disorders among children in China. Methods A total of 6974 (boys 3558, girls 3412) children aged 6-13 years participated in the study. Each participant's height, weight, waist circumference, fasting glucose, triglycerides, total cholesterol, high- density lipoprotein cholesterol, and low-density lipoprotein cholesterol were measured. The type of beverage consumption was determined using a self-administered questionnaire. Results SSBs were consumed regularly by 46.1% of the children. The prevalence [adjusted odds ratio (95% confidence internal (CI)] of obesity was 7.6% [as the reference group (ref.)], 10.1% [1.36(1.07, 1.74)], and 11.6% [1.46(1.21, 1.75)], among children who regularly drank milk, other beverages and SSBs, respectively. Regularly drinking SSBs elevated the likelihood of abdominal obesity [adjusted odds ratio (95% CI): 1.36 (1.17, 1.59)]. The prevalence [adjusted odds ratio (95% CI)] of obesity among children who regularly drank sports/caloric beverages, carbonated beverages, sweet tea, and plant protein beverages was 16.8% [2.00(1.31, 3.07)], 12.7% [1.52(1.23, 1.88)], 11.5% [1.52(1.18, 1.95)], and 10.4% [1.41(1.03, 1.94)], respectively, which was higher than that of regular milk drinkers [7.6 % (ref.)]. The prevalence [adjusted odds ratio (95% CI)] of abdominal obesity among children who regularly drank sweet tea, fruit/vegetable juices, and carbonated beverages was 17.7% [1.55(1.26, 1.90)], 16.2% [1.36(1.09, 1.70)], and 15.3% [1.24(1.03, 1.50)], respectively, which was much higher than that of regular milk drinkers [12.8% (ref.)]. Conclusions Regular SSB consumption was positively related to obesity and abdominal obesity. This relationship should be investigated further using a longitudinal study design. | SHANG Xian Wen LIU Ai Ling ZHANG Qian HU Xiao Qi DU Song Ming MA Jun XU Gui Fa LI Ying GUO Hong Wei DU Lin LI Ting Yu MA Guan Sheng | 2012 | Biomedical and Environmental Sciences2012，25，2： | 23 |
| 19 | LSCHL4 from Japonica Cultivar, Which Is Allelic to NAL 1, Increases Yield of Indica Super Rice 93-11显示文摘在米饭的高产量的基本房屋是改进叶光合的效率和坐标 sourcesink relationshipin 米饭植物。与词法特点和米饭的叶绿素内容有关的量的特点 loci ( QTL )在出发到成熟的阶段离开 weredetected ,并且与旗帜叶形状和叶绿素内容有关的主要 QTL ( qLSCHL4 )在 recombinant 在两个阶段被检测生来的线构造了 usingthe indica 米饭栽培变种 93-11 和装饰用的梨树米饭栽培变种 Nipponbare 。基于地图的克隆和表示分析证明 LSCHL4 对 NAL1 突变而产生之遗传,基因以前在米饭的狭窄的叶异种报导了。与从 Nipponbare 带 LSCHL4 的向量转变的 Overexpression 线和 93-11 (NIL-9311 ) 的一根 near-isogenic 线显著地增加了叶叶绿素内容,扩大旗帜叶尺寸,和改进圆锥花序类型。NIL-9311 的 averageyield 比 93-11 的高是 18.70% 。这些结果显示 LSCHL4 有多种的功能。探索并且节节上升更产量很高的等位基因类似于为超级米饭繁殖的 LSCHL4 提供一个有效方法在提起米饭产量完成新突破并且产生解决全球食物 safety.Key 词的问题的新 ideasfor: | Guang-Heng Zhang Shu-Yu Li Li Wang Wei-Jun Ye Da-Li Zeng Yu-Chun Rao You-Lin Peng Jiang Hu Yao-Long Yang Jie Xu De-Yong Ren Zhen-Yu Gao Li Zhu Guo-Jun Dong Xing-Ming Hu Mei-Xian Yan Long-Biao Guo Chuan-You Li Qian Qian | 2014 | Molecular Plant2014，7，8： | 23 |
| 20 | Annual cost of illness of stomach and esophageal cancer patientsin urban and rural areas in China: A multi-center study显示文摘Objective: Stomach and esophageal cancer are imposing huge threats to the health of Chinese people whereas there were few studies on the financial burden of the two cancers.Methods: Costs per hospitalization of all patients with stomach or esophageal cancer discharged between September 2015 and August 2016 in seven cities/counties in China were collected, together with their demographic information and clinical details. Former patients in the same hospitals were sampled to collect information on annual direct non-medical cost, indirect costs and annual number of hospitalization. Annual direct medical cost was obtained by multiplying cost per hospitalization by annual number of hospitalization. Annual cost of illness(ACI)was obtained by adding the average value of annual direct medical cost, direct non-medical cost and indirect cost,stratified by sex, age, clinical stage, therapy and pathologic type in urban and rural areas. Costs per hospitalization were itemized into eight parts to calculate the proportion of each part. All costs were converted to 2016 US dollars(1 USD=6.6423 RMB).Results: Totally 19,986 cases were included, predominately male. Mean ages of stomach cancer and urban patients were lower than that of esophageal cancer and rural patients. ACI of stomach and esophageal cancer patients were $10,449 and $13,029 in urban areas, and $2,927 and $3,504 in rural areas, respectively. Greater ACI was associated with male, non-elderly patients as well as those who were in stage I and underwent surgeries.Western medicine fee took the largest proportion of cost per hospitalization.Conclusions: The ACI of stomach and esophageal cancer was tremendous and varied substantially among the population in China. Preferential policies of medical insurance should be designed to tackle with this burden and further reduce the health care inequalities. | Zhixun Yang Hongmei Zeng Ruyi Xia Qian Liu Kexin Sun Rongshou Zheng Siwei Zhang Changfa Xia He Li Shuzheng Liu Zhiyi Zhang Yuqin Liu Guizhou Guo Guohui Song Yigong Zhu Xianghong Wu Bingbing Song Xianzhen Liao Yanfang Chen Wenqiang Wei Guihua Zhuang Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，4： | 22 |
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