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| 1 | Fabrication of Ce-doped(Gd2Y)Al5O12/Y3Al5O12 composite-phase scintillation ceramic显示文摘In this paper,a novel Ce(Gd2 Y)Al5O12/Ce:Y3Al5O12(Ce:GYAG/Ce:YAG)composite scintillation ceramic was designed and fabricated by a solid-state reaction method.The phase,luminescence and scintillation properties were investigated.The Ce:GYAG/Ce:YAG composite ceramic consisting of two-phase has a broad emission band ranging from 500 to 750 nm.The total mass attenuation coefficient of Ce:GYAG/Ce:YAG is 0.3864 cm^-1,in between those of Ce:YAG and Ce:GYAG ceramics.In addition,the composite ceramic had a high light yield of 20430 ph/MeV.By controlling the ratio of GYAG and YAG,the composite ceramic can realize a spectrum design and total mass attenuation coefficient control to meet the requirements for wide-X-ray-energy-range detectors. | Shuilin Chen Benxue Jiang Yang Wang Qiangqiang Zhu Qinghua Yang Wanqiu Ma Ge Zhang Long Zhang | 2019 | Journal of Rare Earths2019，37，9： | 3 |
| 2 | Improved Reduced Latency Soft-Cancellation Algorithm for Polar Decoding显示文摘Soft-cancellation(SCAN) is a soft output iterative algorithm widely used in polar decoding. This algorithm has better decoding performance than reduced latency soft-cancellation(RLSC) algorithm, which can effectively reduce the decoding delay of SCAN algorithm by 50% but has obvious performance loss. A modified reduced latency soft-cancellation(MRLSC) algorithm is presented in the paper. Compared with RLSC algorithm, LLR information storage required in MRLSC algorithm can be reduced by about 50%, and better decoding performance can be achieved with only a small increase in decoding delay. The simulation results show that MRLSC algorithm can achieve a maximum block error rate(BLER) performance gain of about 0.4 dB compared with RLSC algorithm when code length is 2048. At the same time, compared with the performance of several other algorithms under(1024, 512) polar codes, the results show that the throughput of proposed MRLSC algorithm has the advantage at the low and medium signal-to-noise ratio(SNR) and better BLER performance at the high SNR. | Xiumin Wang Rui Gu Jun Li Qiangqiang Ma | 2020 | China Communications2020，17，5： | 2 |
| 3 | Synergy of a hierarchical porous morphology and anionic defects of nanosized Li_(4)Ti_(5)O_(12) toward a high-rate and large-capacity lithium-ion battery显示文摘Exploring electrode materials with a high volumetric energy density and high rate capability remains of a great challenge for nanosized-Li_(4)Ti_(5)O_(12)(LTO)batteries.Here,hierarchical porous Ti^(3+)-C-N-Br co-doped LTO(LTOCPB-CC)is synthesized using carboxyl-grafted nanocarbon(CC)and cetylpyridinium bromide(CPB)as combined structure-directing agents.Ti^(4+)-O-CPB/Li^(+)-CC is designed as a new molecular chelate,in which CPB and CC promote the uniform mixing of Li^(+)and Ti^(4+)and control the morphology of TiO_(2) and the final product.The defects(oxygen vacancies and ion dopants)formed during the annealing process increase the electron/hole concentration and reduce the band gap,both of which enhance the n-type electron modification of LTO.As-prepared LTOCPB-CC has a large specific surface area and high tap density,as well as a high electronic conductivity(2.84×10^(-4) S cm^(-1))and ionic conductivity(3.82×10^(-12)cm^(2) s^(-1)),which are responsible for its excellent rate capability(157.7 mA h g^(-1) at 20 C)and stable long-term cycling performance(0.008% fade per cycle after 1000 cycles at 20 C). | Yanan Li Qianlin Chen Qiangqiang Meng Shulai Lei Fangxiang Song Jingbo Ma | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 4 | Regulation of mATG9 trafficking by Src- and ULK1mediated phosphorylation in basal and starvation-induced autophagy显示文摘Autophagy 要求多样的膜来源并且包含 mATG9 的膜 trafficking,在 ATG 家庭的唯一的膜蛋白质。然而,为 autophagy 开始的 mATG9 trafficking 的分子的规定仍然保持不清楚。这里,我们识别了在 mATG9 的 cytosolic N 终点以内排序信号的二保存经典适配器蛋白质,它调停从经由和 AP1/2 建筑群的相互作用的血浆膜和 trans-Golgi 网络(TGN ) 的 mATG9 的 trafficking。在 Tyr8 到的 Src phosphorylates mATG9 处于不着重的条件维持它的 endocytic 和组成的 trafficking。响应饥饿,在由 Src 的 Tyr8 并且在由 ULK1 的 Ser14 的 mATG9 的 phosphorylation 机能上地合作支持在 mATG9 和 AP1/2 建筑群之间的相互作用,为 autophagy 从血浆膜和 juxta 原子的区域导致 mATG9 的再分配到外部水池开始。我们的调查结果揭开 mATG9 trafficking 的新奇机制并且建议基础、导致压力的 autophagy 的协作。 | Changqian Zhou Kaili Ma Ruize Gao Chenglong Mu Linbo Chen Qiangqiang Liu Qian Luo Du Feng Yushan Zhu Quan Chen | 2017 | Cell Research2017，27，2： | 2 |
| 5 | NO x and N 2 O precursors (NH 3 and HCN) from biomass pyrolysis: Co-pyrolysis of amino acids and cellulose, hemicellulose and lignin显示文摘 | Qiangqiang Ren Changsui Zhao Xiaoping Chen Lunbo Duan Yingjie Li Chunyuan Ma | 2010 | Proceedings of the Combustion Institute2010，，： | 1 |
| 6 | How variable progenitor clones construct a largely invariant neocortex显示文摘The neocortex contains a vast collection of diverse neurons organized into distinct layers. While nearly all neocortical neurons are generated by radial glial progenitors(RGPs), it remains largely unclear how a complex yet organized neocortex is constructed reliably and robustly. Here, we show that the division behavior and neuronal output of RGPs are highly constrained with patterned variabilities to support the reliable and robust construction of the mouse neocortex. The neurogenic process of RGPs can be well-approximated by a consistent Poisson-like process unfolding over time, producing deep to superficial layer neurons progressively. The exact neuronal outputs regarding layer occupation are variable;yet, this variability is constrained systematically to support all layer formation, largely reflecting the variable intermediate progenitor generation and RGP neurogenic entry and exit timing differences. Together, these results define the fundamental features of neocortical neurogenesis with a balanced reliability and variability for the construction of the complex neocortex. | Zhongfu Shen Jiajun Yang Qiangqiang Zhang Kuiyu Wang Xiaohui Lv Xiaolin Hu Jian Ma Song-Hai Shi | 2024 | National Science Review2024，11，1： | 0 |
| 7 | Study on the mechanism of cholic acid derivatives in traditional Chinese medicine based on the regulation of gene expression显示文摘Objective:To investigate the pharmacological action and mechanism of cholic acid derivatives in traditional Chinese medicine(TCM)based on the regulation of gene expression.Methods:Genome-wide gene expression profiles of Michigan Cancer Foundation-7(MCF-7)cells treated with or without 4 cholic acid derivatives were detected by gene chip technology.Similarities in upregulated and downregulated genes were analyzed using the Connectivity Map(CMap)database.The affinity between cholic acid derivatives and the potential target was confirmed by molecular docking.The cholic acid derivative-regulated pathway enrichment analysis was performed by the STRING database,and the potential pathway was confirmed by in vitro experiments on MD Anderson-Metastatic Breast-231(MDA-MB-231)cells.Results:Compared with the reference genome in the CMap database,the gene expression profiles of cholic acid derivatives were similar to those of antipsychotic,anticancer,anti-inflammatory,and antiinfective drugs.Among them,4 derivatives were associated with antianxiety drugs,and molecular docking results showed that these compounds may act by binding to the ligand-binding site of gammaaminobutyric acid(GABA)receptors.Moreover,the cytoskeletal pathway is one of the pathways enriched in the derivatives.Of them,ursodeoxycholic acid showed significant inhibitory activity on the cytoskeleton formation of MDA-MB-231 cells.Conclusion:The gene expression detection method,combined with CMap and pathway enrichment analysis,could be used to study the mechanism of the active ingredients of TCM.In addition,our research showed that cholic acid derivatives have a potential affinity for membrane receptors,where they can exert anxiolytic activity by modulating opioid receptor,GABA receptor,and dopamine receptor.Moreover,ursodeoxycholic and chenodeoxycholic acid inhibit cytoskeleton formation,probably by acting on membrane proteins to activate the corresponding cytoskeletal pathways. | Yongchun Huang Jie Zhang Pengxiang Zhao Yufeng Ma Qiangqiang Jia Shoude Zhang | 2023 | Journal of Traditional Chinese Medical Sciences2023，10，1： | 0 |
| 8 | Investigation and evaluation of randomized controlled trials for interventions involving artificial intelligence显示文摘Objective Complete and transparent reporting is of critical importance for randomized controlled trials(RCTs).The present study aimed to determine the reporting quality and methodological quality of RCTs for interventions involving artificial intelligence(AI)and their protocols.Methods We searched MEDLINE(via PubMed),Embase,Web of Science,CBMdisc,Wanfang Data,and CNKI from January 1,2016,to November 11,2020,to collect RCTs involving AI.We also extracted the protocol of each included RCT if it could be obtained.CONSORT-AI(Consolidated Standards of Reporting Trials-Artificial Intelligence)statement and Cochrane Collaboration’s tool for assessing risk of bias(ROB)were used to evaluate the reporting quality and methodological quality,respectively,and SPIRIT-AI(The Standard Protocol Items:Recommendations for Interventional Trials-Artificial Intelligence)statement was used to evaluate the reporting quality of the protocols.The associations of the reporting rate of CONSORT-AI with the publication year,journal’s impact factor(IF),number of authors,sample size,and first author’s country were analyzed univariately using Pearson’s chi-squared test,or Fisher’s exact test if the expected values in any of the cells were below 5.The compliance of the retrieved protocols to SPIRIT-AI was presented descriptively.Results Overall,29 RCTs and three protocols were considered eligible.The CONSORT-AI items“title and abstract”and“interpretation of results”were reported by all RCTs,with the items with the lowest reporting rates being“funding”(0),“implementation”(3.5%),and“harms”(3.5%).The risk of bias was high in 13(44.8%)RCTs and not clear in 15(51.7%)RCTs.Only one RCT(3.5%)had a low risk of bias.The compliance was not significantly different in terms of the publication year,journal’s IF,number of authors,sample size,or first author’s country.Ten of the 35 SPIRIT-AI items(funding,participant timeline,allocation concealment mechanism,implementation,data management,auditing,declaration of interests,access to data,informed consent materials and biological specimens)were not reported by any of the three protocols.Conclusions The reporting and methodological quality of RCTs involving AI need to be improved.Because of the limited availability of protocols,their quality could not be fully judged.Following the CONSORT-AI and SPIRIT-AI statements and with appropriate guidance on the risk of bias when designing and reporting AI-related RCTs can promote standardization and transparency. | Jianjian Wang Shouyuan Wu Qiangqiang Guo Hui Lan Estill Janne Ling Wang Juanjuan Zhang Qi Wang Yang Song Nan Yang Xufei Luo Qi Zhou Qianling Shi Xuan Yu Yanfang Ma Joseph LMathew Hyeong Sik Ahn Myeong Soo Lee Yaolong Chen | 2021 | Intelligent Medicine2021，1，2： | 0 |
| 9 | The decrease of salinity in lakes on the Tibetan Plateau between 2000 and 2019 based on remote sensing model inversions显示文摘Salinity is an essential factor of lake water environments and aquatic systems.It is also sensitive to climatic changes and human activities based on concentration variations of solved minerals.However,there are few consecutively temporal studies on lake salinity variations on the Tibetan Plateau because the harsh environmental conditions make it diffcult to carry out in-situ observations for several lakes.In this study.we constructed a remote sensing retrieval model for lake salinity based on 87 in-situ lake investigations;moreover,interannual lake salinity and associated variations from 152 lakes larger than 50 km2 were analyzed on the Tibetan Plateau.A significant decreasing trend in lake salinity was observed between 2000 and 2019(p<0.01).The spatial variation of lake salinity was negatively correlated with lake area changes,and the optical characteristics of salt mineral solutions were generally positively correlated with mineral concentration based on the absorption coefficients of ionic solutions.The decreasing trend of lake salinity was not directly affected by the.precipitation,but was,potentially dominated by the expanding lake water volume.This study improves the understanding of regional water environmental changes and management efficacy of water resources. | Chong Liu Liping Zhu Junbo Wang Jianting Ju Qingfeng Ma Qiangqiang Kou | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
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