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| 1 | Chemical Characteristics and Environmental Records of a Snow-Pit at the Glacier No.12 in the Laohugou Valley, Qilian Mountains显示文摘In June 2006, samples were collected from a 90 cm snow-pit at an elevation of 5 040 m a.s.l. in the northern branch firn basin of the Glacier No. 12, Laohugou Valley, in the western part of Qilian Mountain, China. Oxygen isotopes(δ18O) and major soluble ions were measured. Results showed that Ca2+ is the dominant cation, and SO42- is the dominant anion. All major ions have close positive correlations with eachother except NO3- and NH4+. δ18O show positive correlation with air temperature. The method of correlation analysis, sea-salt ion tracer and trend analysis were used to determine the source of the chemical components. The correlation analysis and HYSPLIT backward trajectory analysis suggest that atmospheric soluble dust species dominate the chemical signature. | Xiaoqing Cui Jiawen Ren Xiang Qin Weijun Sun Guangming Yu Zebin Wang Weigang Liu | 2014 | Journal of Earth Science2014，25，2： | 4 |
| 2 | Identification and isolation of Mu-flanking fragments from maize显示文摘Transposable elements have been utilized as mutagens to create mutant libraries for functional genomics. Isolation of genomic seg-ments flanking the insertion Mutator (Mu) is a key step in insertion mutagenesis studies. Herein, we adopted a modified AFLP method to identify and isolate Mu-flanking fragments from maize. The method consists of the following steps: 1) double-digestion of genomic DNA with Bgl II/Msp I and ligation of digested fragments to the Bgl II-and Msp I-adaptors; 2) enrichment of a subset of Bgl II/Msp I fragments followed by selective amplification of the Mu-flanking fragments; 3) simultaneous display of AFLP bands derived from the flanking re-gions for both insert and native Mu transposons; 4) identification and isolation of AFLP bands resulting from Mu insertions by comparing the banding profiles between Mu-induced mutants and their parental lines; and 5) confirmation of flanking fragments related to these Mu insertions. Using this approach, we have isolated flanking fragment(s) resulting from Mu insertion for every Mu-induced mutant, and one such fragment, M196-FF, is found to contain a partial sequence of the DNA topoisomerase I gene Top1. Moreover, the modified AFLP method including all restriction enzymes, adaptors and primers has been optimized in this study. The modified AFLP method has been proved to be simple and efficient in the isolation of Mu-flanking fragments and will find its usefulness in the functional genomics of maize. | Yijun Wang Guangming Yin Qin Yang Jihua Tang Xiaomin Lu Schuyler S. Korban Mmghang Xu | 2008 | Journal of Genetics and Genomics2008，35，4： | 4 |
| 3 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 4 | A mathematical modeling study of the HIV epidemics at two rural townships in the Liangshan Prefecture of the Sichuan Province of China显示文摘Background:As a response to a severe HIV epidemic in the Liangshan Prefecture,one of the worst in China,population based HIV interventions,including two population-wide HIV screening,have been carried out since 2005 at two townships in a remote mountainous region of Liangshan.The objective of our mathematical modeling study is to assess the temporal dynamics of the HIV epidemic in the two townships based on the data collected in the study area during the period 2005e2010.Methods:A mathematical model was set up to describe the population dynamics of HIV transmission in study area.The model was calibrated by fitting it to the HIV testing and treatment data from 2005 to 2008.Validation of the model was done by comparing its predicted value of HIV prevalence in 2010 to the prevalence data obtained in the 2010 population wide HIV testing.The validated model was used to produce estimation of HIV incidence,prevalence and death.Results:Our model estimations show that population-based HIV interventions have significantly slowed down the rise of the HIV epidemic in the two townships.Over the five-year period from 2005 to 2010,the year-over-year rate of increase in HIV incidence,prevalence,and death has declined by 91.5%,28.7%,and 52.3%,respectively.Conclusion:Mathematical models,when integrated with epidemiological and surveillance data,can be an effective tool for predicting the temporal dynamics of HIV and assessing the impacts of HIV interventions. | Zhimin Su Caiting Dong Ping Li Hongxia Deng Yuhan Gong Shiyong Zhong Min Wu Yuhua Ruan Guangming Qin Wen Yang Yiming Shao Michael Li | 2016 | Infectious Disease Modelling2016，1，1： | 2 |
| 5 | Improvement of collision-detection algorithm based on OBB显示文摘 | Zhang Qin Huang Kun Li Guangming | 2003 | Journal of Huazhong University of Science and Technology:Natural Science Edition2003，31，1： | 1 |
| 6 | High- temperature magmatic fluid exsolved from magma at the Duolong porphyry copper-gold deposit, Northem Tibet显示文摘 | Li Jinxiang Li Guangming Qin Kezhang | 2011 | Geofluids2011，11，1： | 1 |
| 7 | Mineralogy and mineral chemistry of the Cretaceous Duolong gold-rich porphyry copper deposit in the Bangongco arc, northern Tibet显示文摘 | Li Jinxiang Li Guangming Qin Kezhang | 2012 | Resource Geology2012，62，1： | 1 |
| 8 | Highly oxidized magma and fluid evolution of Miocene Qulong giant porphyry Cu-Mo deposit, Southern Tibet, China显示文摘 | Xiao Bo Qin Kezhang Li Guangming | 2012 | Resource Geology2012，62，1： | 1 |
| 9 | Association of platelet- monocyte aggregates with platelet activation, systemic inflammation, and myocardial injury in patients with Non - ST Elevation acute coronary syndromes显示文摘 | Zhang Songzhao Jin Yaping Qin Guangming | 2007 | Clin Cardiol2007，30，： | 1 |
| 10 | Formation of the giant Chalukou porphy Mo deposit in northern Great Xing' an Range, NE China: Partial melting of juvenile lower crust in intraplate extension environment显示文摘 | Li Zhenzhen Qin Kezhang Li Guangming | 2014 | Lithos2014，，： | 1 |
| 11 | Performance of a Single-Stage Auto- Cascade Refrigerator Operating With a Rectifying Col- umn at the Temperature Level of -60C 显示文摘 | WANG Qin CUI Kang SUN Tengfei CHEN Fusheng CHEN Guangming | 2011 | Journal of Zhejiang University-Science A (Appl Physics z Eng)2011，12，13： | 1 |
| 12 | High-temperature magmatic fluid exsolved from magma at the Duobuza porphyry cop- per-gold deposit, Northern Tibet 显示文摘 | Li Jinxiang Li Guangming Qin Kezhang | 2011 | Geofluids2011，，11： | 1 |
| 13 | Geology and hydro- thermal alteration of the duobuza gold-rich porphyry copper district in the Bangongeo Metallogenic Belt, Northwestern Tibet显示文摘 | Li Guangming Li Jinxiang Qin Kezhang | 2011 | Re- source Geology2011，62，1： | 1 |
| 14 | Geochronology, geochemistry, and zircon Hf isotopic compositions of Mesozoic intermediate-felsic intrusions in central Tibet: Petrogenetic and tectonic implications显示文摘 | Li Jinxiang Qin Kezhang Li Guangming | 2014 | Lithos2014，19，： | 1 |
| 15 | Magmatic- hydrothermal evolution of the Cretaceous Duolong gold-rich porphyry copper deposit in the Bangongco metallogenic belt, Tibet: Evidence from U-Pb and 4~ArPgAr geochronology显示文摘 | Li Jinxiang Qin Kezhang Li Guangming | 2011 | Journal of Asian Earth Sciences2011，41，： | 1 |
| 16 | Syphilis Among Female Sex Workers in Southwestern China: Potential for HIV Transmission显示文摘 | Yuhua Ruan Xiaoyun Cao Han-Zhu Qian Li Zhang Guangming Qin Zhengqing Jiang Benli Song Wei Hu Shu Liang Kanglin Chen Ye Yang Xinxu Li Jun Wang Xi Chen Chun Hao Yanhui Song Hui Xing Ning Wang Yiming Shao | 2006 | Sexually Transmitted Diseases2006，，12： | 1 |
| 17 | Thermodynamic performance analysis of gas-fired air-cooled adiabatic absorption refrigeration systems显示文摘 | Wang Lin Chen Guangming Wang Qin | 2007 | Applied Thermal Engineering2007，27，89： | 1 |
| 18 | Geology, Mineralogy Ar - Ar age and Mineral Assem- blage of Eocene Skarn Cu - Au Mo deposits in theSoutheastern Gangdese Arc, Southern Tibet: Implications for Deep Exploration 显示文摘 | LI GUANGMING QIN KEZHANG DING KUISHOU | 2006 | Resource Geology2006，，56： | 1 |
| 19 | Magmatichydrothermal evolution of the Cretaceous Duolong gold-rich porphyry copper deposit in the Bangongco metallogenic belt,Tibet:evidence from U-Pb and 40Ar/39Ar geochronology显示文摘 | Li Jinxiang Qin Kezhang Li Guangming | 2011 | Journal of Asian Earth Sciences2011，41，6： | 1 |
| 20 | Geology and hydrothermal alteration of the Duobuza gold-rich porphyry copper district in the Bangongco metallogenetic belt,northwestern Tibet显示文摘 | Li Guangming Li Jinxing Qin Kezhang | 2012 | Resource Geology2012，62，1： | 1 |
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