|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The M_S7.1 Yushu earthquake surface rupture and large historical earthquakes on the Garzê-Yushu Fault显示文摘As revealed by field investigations,the co-seismic surface rupture zone of the 2010 MS7.1 Yushu earthquake,Qinghai is a characteristic sinistral strike-slip feature consisting of three distinct sinistral primary ruptures,with an overall strike of 310°-320° and a total length of 31 km.In addition,an approximately 2-km-long en-echelon tensile fissure zone was found east of Longbao Town;if this site is taken as the north end of the rupture zone,then the rupture had a total length of ~51 km.The surface rupture zone is composed of a series of fissures arranged in an en-echelon or alternating relationship between compressive bulges and tensile fissures,with a measured maximum horizontal displacement of 1.8 m.The surface rupture zone extends along the mapped Garzê-Yushu Fault,which implicates it as the seismogenic fault for this earthquake.Historically,a few earthquakes with a magnitude of about 7 have occurred along the fault,and additionally traces of paleoearthquakes are evident that characterize the short-period recurrence interval of large earthquakes here.Similar to the seismogenic process of the 2008 Wenchuan earthquake,the Yushu earthquake is also due to the stress accumulation and release on the block boundaries resulting from the eastward expansion of Qinghai-Tibet Plateau.However,in contrast with the Wenchuan earthquake,the Yushu earthquake had a sinistral strike-slip mechanism resulting from the uneven eastward extrusion of the Baryan Har and Sichuan-Yunnan fault blocks. | CHEN LiChun WANG Hu RAN YongKang SUN XinZhe SU GuiWu WANG Ji TAN XiBin LI ZhiMin ZHANG XiaoQing | 2010 | Chinese Science Bulletin2010，55，31： | 17 |
| 2 | Cancer metabolism and tumor microenvironment:fostering each other?显示文摘The changes associated with malignancy are not only in cancer cells but also in environment in which cancer cells live.Metabolic reprogramming supports tumor cells’high demand of biogenesis for their rapid proliferation,and helps tumor cells to survive under certain genetic or environmental stresses.Emerging evidence suggests that metabolic alteration is ultimately and tightly associated with genetic changes,in particular the dysregulation of key oncogenic and tumor suppressive signaling pathways.Cancer cells activate HIF signaling even in the presence of oxygen and in the absence of growth factor stimulation.This cancer metabolic phenotype,described firstly by German physiologist Otto Warburg,ensures enhanced glycolytic metabolism for the biosynthesis of macromolecules.The conception of metabolite signaling,i.e.,metabolites are regulators of cell signaling,provides novel insights into how reactive oxygen species(ROS)and other metabolites deregulation may regulate redox homeostasis,epigenetics,and proliferation of cancer cells.Moreover,the unveiling of noncanonical functions of metabolic enzymes,such as the moonlighting functions of phosphoglycerate kinase 1(PGK1),reassures the importance of metabolism in cancer development.The metabolic,microRNAs,and ncRNAs alterations in cancer cells can be sorted and delivered either to intercellular matrix or to cancer adjacent cells to shape cancer microenvironment via media such as exosome.Among them,cancer microenvironmental cells are immune cells which exert profound effects on cancer cells.Understanding of all these processes is a prerequisite for the development of a more effective strategy to contain cancers. | Yiyuan Yuan Huimin Li Wang Pu Leilei Chen Dong Guo Hongfei Jiang Bo He Siyuan Qin Kui Wang Na Li Jingwei Feng Jing Wen Shipeng Cheng Yaguang Zhang Weiwei Yang Dan Ye Zhimin Lu Canhua Huang Jun Mei Hua-Feng Zhang Ping Gao Peng Jiang Shicheng Su Bing Sun Shi-Min Zhao | 2022 | Science China(Life Sciences)2022，65，2： | 5 |
| 3 | Safety and efficacy of Yupingfeng granules in children with recurrent respiratory tract infection:A randomized clinical trial显示文摘Importance:Recurrent respiratory tract infection(RRTI)is common in children.Inappropriate RRTI treatment will lead to asthma and other diseases,thereby seriously affecting the growth and physical health of children.Immune function modulation can prevent and alleviate childhood RRTI.Yupingfeng(YPF),a patented traditional Chinese medicine(TCM),has immunomodulatory effects and is widely used in China to treat children with RRTI.Objective:To evaluate the safety and efficacy of YPF monotherapy in treating children with RRTI.Methods:This multicenter,randomized,double-blind,double-simulation,noninferiority clinical trial was conducted from January 2015 to August 2017,with an 8-week treatment period and 52-week follow-up after the drug withdrawal.Children aged 2–6 years with RRTI meeting the inclusion and exclusion criteria were enrolled in 13 hospitals in China and divided randomly into three groups(2:2:1 ratio)to receive YPF,pidotimod,or placebo.The primary outcome was the proportion of RRTI returning to normal standard level during the follow-up.The secondary outcomes were reduction in the number of RRTI recurrences,effect on clinical symptoms(in accord with TCM practice),effect per symptom,and safety.The trial was registered at the Chinese Clinical Trials Registry(www.chictr.org.cn)under the unique identifier ChiCTR-IPR-15006847.Results:Three hundred and fifty-one children were enrolled and randomly assigned to 3 groups;124,125,and 61 children in the YPF,pidotimod,and placebo groups,respectively,had completed the trial.During the follow-up,the proportion of RRTI returning to normal standard level was 73.13%,67.15%,and 38.81%with YPF,pidotimod,and placebo,respectively(P<0.0001).The proportion of cases who returned to normal standard level in the YPF group was 34.32%higher than that in the placebo group.The safety profile did not significantly differ among the groups.Interpretation:YPF granules were noninferior to the active control drug pidotimod oral solution for the treatment of RRTI in children,and were superior to placebo,with a high safety profile. | Baoping Xu Xinmin Li Siyuan Hu Yixiao Bao Fengmei Chen Zhimin Chen Yonggang Du Enmei Liu Yufeng Liu Qinghui Mou Baoling Su Bo Wang Jianwen Xu Guiping Xu Qiaozhi Yang Liwei Gao Xiaohui Liu Lei Li Rong Ma Kunling Shen | 2022 | Pediatric Investigation2022，6，2： | 3 |
| 4 | Oscillating Cellulase Adsorption and Enhanced Lignocellulose Hydrolysis upon Ultrasound Treatment显示文摘We investigated the effects of ultrasound treatment on cellulase adsorption and lignocellulose hydrolysis.The activity of cellulase remained constant upon lowpower ultrasound treatment(<120 W) and decreased using high-power ultrasound(>280 W).Oscillating cellulase adsorption occurred upon ultrasound treatment with any intensity.The maxima for desorption and adsorption were41.9 and 83.1%,respectively,during 1 h of 90 W ultrasound treatment at 50 °C.A comparison between the shorttime with long-time ultrasound experiments indicated that ultrasound treatment tended to desorb cellulase from substrate.However,ultrasound treatment also led to further surface erosion of biomass,which increased cellulase accessibility.These joint actions of ultrasound treatment induced the oscillating adsorption of cellulase.The increase in cellulase accessibility caused by ultrasound treatment led to a significant enhancement in lignocellulose hydrolysis. | Rongxin Su Renjun Yang Yang Jifeng Ruoyu Du Renliang Huang Wei Qi Zhimin He | 2017 | Transactions of Tianjin University2017，23，1： | 3 |
| 5 | Expression analysis of the calcineurin B-like gene family in rice ( Oryza sativa L.) under environmental stresses显示文摘 | Zhimin Gu Bojun Ma Yan Jiang Zhiwei Chen Xuan Su Hongsheng Zhang | 2008 | Gene2008，，1： | 3 |
| 6 | Palladium nanoclusters immobilized on defective nanodiamond-graphene core-shell supports for semihydrogenation of phenylacetylene显示文摘We report a nanocarbon material with nanodiamond(ND) core and graphene shell(ND@G) as a support for Pd nanocatalysts. The designed catalyst performed good selectivity of styrene(85.2%) at full conversion of phenylacetylene and superior stability under mild conditions. Supported Pd catalysts are characterized by means of high resolution transmission electron microscopy(HRTEM), Raman, X-ray diffraction(XRD), X-ray photoelectron spectroscopy(XPS) and H2 temperature-programmed reduction(H2-TPR).The results clearly show that formation of the strong metal-support interaction(SMSI) between Pd nanoclusters and the defective graphene shell helpfully modifies the selectivity and stability of the Pd-based catalysts. | Fei Huang Zhimin Jia Jiangyong Diao Hua Yuan Dangsheng Su Hongyang Liu | 2019 | Journal of Energy Chemistry2019，28，6： | 2 |
| 7 | A mathematical modeling study of the HIV epidemics at two rural townships in the Liangshan Prefecture of the Sichuan Province of China显示文摘Background:As a response to a severe HIV epidemic in the Liangshan Prefecture,one of the worst in China,population based HIV interventions,including two population-wide HIV screening,have been carried out since 2005 at two townships in a remote mountainous region of Liangshan.The objective of our mathematical modeling study is to assess the temporal dynamics of the HIV epidemic in the two townships based on the data collected in the study area during the period 2005e2010.Methods:A mathematical model was set up to describe the population dynamics of HIV transmission in study area.The model was calibrated by fitting it to the HIV testing and treatment data from 2005 to 2008.Validation of the model was done by comparing its predicted value of HIV prevalence in 2010 to the prevalence data obtained in the 2010 population wide HIV testing.The validated model was used to produce estimation of HIV incidence,prevalence and death.Results:Our model estimations show that population-based HIV interventions have significantly slowed down the rise of the HIV epidemic in the two townships.Over the five-year period from 2005 to 2010,the year-over-year rate of increase in HIV incidence,prevalence,and death has declined by 91.5%,28.7%,and 52.3%,respectively.Conclusion:Mathematical models,when integrated with epidemiological and surveillance data,can be an effective tool for predicting the temporal dynamics of HIV and assessing the impacts of HIV interventions. | Zhimin Su Caiting Dong Ping Li Hongxia Deng Yuhan Gong Shiyong Zhong Min Wu Yuhua Ruan Guangming Qin Wen Yang Yiming Shao Michael Li | 2016 | Infectious Disease Modelling2016，1，1： | 2 |
| 8 | Effects of fish meal replacement with Chlorella meal on growth performance,pigmentation,and liver health of largemouth bass(Micropterus salmoides)显示文摘Chlorella meal is a potential protein source for aquafeeds.However,the physiological response of carnivorous fish fed Chlorella meal remains elusive.This study evaluated the effects of replacing dietary fish meal with Chlorella meal on growth performance,pigmentation,and liver health in largemouth bass.Five diets were formulated to replace dietary fish meal of 0%(C0,control),25%(C25),50%(C50),75%(C75),and 100%(C100)with Chlorella meal,respectively.Total 300 fish(17.6±0.03 g)were randomly assigned to 15 tanks(3 tanks/group).Fish were fed the experimental diet twice daily for 8 weeks.The increased dietary Chlorella meal quadratically influenced the final body weight(FBW),weight gain rate(WGR),specific growth rate(SGR),and feed intake(FI),which were significantly lower in the C100 group than in the other groups(P<0.05).The feed conversion ratio(FCR)increased linearly or quadratically with dietary Chlorella meal.Dietary Chlorella meal linearly or quadratically increased the lutein content of plasma,liver,and dorsal muscle of largemouth bass(P<0.05).Compared to the C0 group,all supplemented Chlorella meal groups significantly improved the yellowness(b*)of the dorsal body(1.5 to 2.0 fold),abdominal body(1.5 to 1.8 fold),and dorsal muscle(3.8 to 5.4 fold)of largemouth bass(P<0.05).In addition,compared to the C0 group,the liver vacuolation area of fish was significantly increased in the C75 and C100 groups(P<0.05).Transcriptional levels of apoptosis-related genes of b-cell lymphoma-2(bcl2),caspase-9-like(casp9),and caspase-3a(casp3)were markedly upregulated(0.9 to 1.6 fold)in the C100 group compared to the C0 group(P<0.05).Based on the quadratic regression analysis between FBW,WGR,or SGR and dietary Chlorella meal level,largemouth bass had the best growth when replacing 31.7%to 32.6%of fish meal with 15.03%to 15.43%dietary Chlorella meal.The present results indicated that dietary supplementation with Chlorella meal(11.85%to 47.45%)significantly enhanced the pigmentation;however,total replacement of fish meal(40%)with Chlorella meal(47.45%)caused growth retardation,apoptosis,and liver damage in largemouth bass. | Longwei Xi Qisheng Lu Yulong Liu Jingzhi Su Wen Chen Yulong Gong Dong Han Yunxia Yang Zhimin Zhang Junyan Jin Haokun Liu Xiaoming Zhu Shouqi Xie | 2022 | Animal Nutrition2022，，3： | 2 |
| 9 | Preparation and Dielectric Properties of Nonstoichiometric β-SiC Powder by Combustion Synthesis显示文摘The nonstoichiometric β-SiC powders were synthesized via combustion reaction of Si and C system in a 0.1 MPa nitrogen atmosphere, using Teflon as the chemical activator. The prepared powders were invistigated by XRD and Raman spectra. The results indicates that the cell parameters of all the prepared β-SiC powder are smaller than the standard value of β-SiC because of generation of CSi defects. The complex permittivity of prepared products was carried out in the frequency range of 8.2-12.4 GHz. It shows that the dielectric property of prepared β-SiC powder decrease with increasing PTFE content. The effect of CSi defects on dielectric property of β-SiC powder has been discussed. | Xiaolei Su Wancheng Zhou Zhimin Li Fa Luo Dongmei Zhu | 2009 | Journal of Materials Science & Technology2009，25，3： | 2 |
| 10 | A Low-Cost and Easily Prepared Manganese Carbonate as an Effi cient Catalyst for Aerobic Oxidation of 5-Hydroxymethylfurfural to 2,5-Diformylfuran显示文摘A low-cost and easily prepared manganese carbonate(Mn CO_3) has been synthesized for catalytic conversion of 5-hydroxymethylfurfural(5-HMF) to 2,5-diformylfuran(DFF). The properties and morphology of the manganese carbonate were measured by SEM,XRD,TGA,BET and XPS. In this method,no harsh reaction conditions were required,and it was a simple and green process for the oxidation of 5-HMF into DFF. To achieve an optimum DFF yield,different reaction conditions,including reaction temperature,reaction time,catalyst amount,and solvents were investigated. Results from the experiments indicated that the highest DFF yield of 86.9% was obtained at 120 °C under atmospheric oxygen pressure after 6h. Finally,Mn CO_3 could be used at least five times with considerable stability. | Wei Qi Jie Fang 1 Zhenzhen Yang Bingqi Li Rongxin Su Zhimin He | 2018 | Transactions of Tianjin University2018，24，4： | 2 |
| 11 | Tandem Biocatalysis by CotA-TJ102@UIO-66-NH2 and Novozym 435 for Highly Selective Transformation of HMF into FDCA显示文摘2,5-Furandicarboxylic acid (FDCA) is a potential biorenewable chemical for applications including plastics, polyamides, drugs, etc. The selective biosynthesis of FDCA from 5-hydroxymethylfurfural (HMF) by a speci c enzyme poses a great challenge. In this study, we reported an e cient strategy to produce FDCA from HMF by the tandem biocatalysis of laccase (CotA-TJ102@UIO-66-NH 2 ) and Novozym 435. For the rst step, a nanoparticle metal organic framework was synthesized as a carrier to immobilize CotA-TJ102@UIO-66-NH 2 , which was assigned for the production of 5-formyl-2-furancarboxylic acid (FFCA) and featured an enzyme loading of 255.54 mg/g, speci c activity of 135.90 U/mg, and solid loading ratio of 99.65%. Under optimal conditions, an ideal FFCA yield of 98.5% was achieved, and the CotA-TJ102@UIO-66-NH2 pre- sented a high recycling capacity after 10 cycles. For the second step, Novozym 435 was applied for the further conversion of FFCA into FDCA, presenting a high FDCA yield of 95.5% under the optimized conditions. Novozym 435 also exhibited a high recyclability after eight cycles. As a result, the tandem biocatalysis strategy provided a 94.2% FDCA yield from HMF, indicating its excellence as a method for FDCA production. | Xin Chang Chengyu Zhang Lan Gao Xiao Liu Shengping You Wei Qi Kang Wang Xin Guo Rongxin Su Han Lu Zhimin He | 2019 | Transactions of Tianjin University2019，25，5： | 2 |
| 12 | Sr speciation in producing SrCO_3 with celestite显示文摘Strontium speciation transferring in strontium residue and mixing strontium ore are investigated with extracting experiment, X-ray powder diffraction(XRD), X-ray fluorescence spectrometer(XRF) and Atomic Absorption Spectroscopy(AAS). The results show that there are strontium carbonate, strontium sulfate, strontium sulfide, and a little amount of strontium silicate and strontium ferrite in strontium residue. Impurities in strontium residue mainly contain carbonate and oxide of calcium, iron, magnesium and aluminum etc. The amount of strontium sulfide in strontium residue is larger than that in strontium ore. And a little strontium silicate and strontium ferrite are found in strontium ore. It is concluded that acid soluble method is used firstly in the process of producing strontium carbonate from mixing strontium ore. In addition, mechanical smash method and surface active treatment to strontium samples are beneficial to the ratio-leaching increase of strontium. The research achievement helps to save energy and decrease pollutants emission in strontium processing industry. | LIU Chenglun ZHANG Li XU Longjun SU Zhimin XIE Taiping WANG Yuan | 2014 | Chinese Journal Of Geochemistry2014，33，3： | 2 |
| 13 | Multilevel structural nature and interactions of bovine serum albumin during heat-induced aggregation process显示文摘 | SU Rongxin QI Wei HE Zhimin | 2008 | Food Hydroeolloids2008，22，6： | 1 |
| 14 | A one-model approach to congestion in data envelopment analysis显示文摘 | W.W.Cooper Hong hui Deng Zhimin M.Huang Su san X.Li | | 0，，04： | 1 |
| 15 | Facile method to synthesize graphene-ZnS nanocomposites: preparation and application in bioelectrochemistry of hemoglobin显示文摘 | Li Wang Wei Qi Rongxin Su Zhimin He | 2013 | Journal of Solid State Electrochemistry2013，，10： | 1 |
| 16 | An artifact- centric approach to dynamic modification of work- flow execution显示文摘 | Xu Wei Su Jianwen Yan Zhimin | 2011 | Lecture Notes in Computer Sci- ence2011，7044，： | 1 |
| 17 | How do brand communities generate brand relationships? Intermediate mechanisms显示文摘 | Zhimin Zhou Qiyuan Zhang Chenting Su Nan Zhou | 2011 | Journal of Business Research2011，，7： | 1 |
| 18 | Comparative QSAR modeling of antitumor activity of ARC-111 analogues using stepwise MLR, PLS, and ANN techniques显示文摘 | Yanjun Yu Rongxin Su Libing Wang Wei Qi Zhimin He | 2010 | Medicinal Chemistry Research2010，，9： | 1 |
| 19 | Experimental study on composite FRP-anchoring technology显示文摘 | HU Pengcheng WU Zhimin SU Ying | 2010 | Journal of Disaster Prevention and Mitigation Engineering2010，30，3： | 1 |
| 20 | Controlled adsorption of cellulase onto pretreated corncob by pH adjustment显示文摘 | Ruoyu Du Rongxin Su Xuan Li Xiaowei Tantai Zhaohui Liu Jifeng Yang Wei Qi Zhimin He | 2012 | Cellulose2012，，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员