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| 1 | Research advances in the Mesozoic tectonic regimes during the formation of Jiaodong ore cluster area显示文摘在诺思中国的东方区域在中生代时代在 Jiaodong 矿石簇区域和相关构造政体转变把构造政体的进展基于研究,在这篇论文,我们首先总结要求后面被学习的一些关键问题。然后,我们建议一条途径到处理这些问题。在 Jiaodong 矿石的金存款聚类区域,这被知道,它具有不同矿化作用式样,空间 istributions 和地质的背景,可能作为从在中生代的至少一个地质的事件的结果。到现在为止,特别在上述事件的 geodynamic 机制上,关于时间的进化和空间迁居顺序的这种研究是远非足够的。而且,描述行动模式和构造动态政体的时间空间的框架并且提出每构造动态政体的相对贡献因为 metallogensis 是静止的质问到地质学家在 Jiaodong 的形成上学习的份量上矿石簇区域。根据地区性的构造分析,结构的动力学,观察和矿化作用网络的探索的解释,我们建议有一些的一个 geological-physical-chemical 模型抑制从全面分析发源。我们然后使用这个模型模仿结构的变丑,热运输,液体流动和化学反应的联合过程。获得的结果显示模型在进一步在 Jiaodong 矿石簇区域并且在进一步理解集体 metallogensis 的性质分析构造政体的时间空间的进化小道是有效的。 | DENG Jun YANG Liqiang GE Liangsheng WANG Qingfei ZHANG Jing GAO Bangfei ZHOU Yinghua JIANG Shaoqing | 2006 | Progress in Natural Science:Materials International2006，16，8： | 51 |
| 2 | Sediment-hosted Pb-Zn Deposits in Southwest Sanjiang Tethys and Kangdian Area on the Western Margin of Yangtze Craton显示文摘Yangtze Craton 的西方的边缘作为重要招待沉积的基础金属的总数簇被知道,特别为在中国的 PbZn 存款,例如 Jinding, Daliangzi, Tianbaoshan, Kuangshanchang 和 Qinlinchang 存款。与在世界上的经典 MVT 存款比较,基于招待沉积的 Pb-Zn 存款的基本地质学,这份报纸集中于这存款的 temporalspatial 分发进一步讨论它的大规模矿化作用和构造进化历史。在 SW Sanjiang Thethys, Jinding 沉积物典型地在沙岩和忍受角砾岩的沙岩主要是控制差错、招待的戳,而 MVT 类型存款被岩性学控制并且为招待碳酸盐的岩石与强壮的偏爱差错 / 破裂。最重要地, Jinding PbZn 沉积物不同于它在一个大陆人碰撞地区以内在强烈使变形的低岬盆在被形成的招待沉积的 PbZn 存款的另外的类型。在 Kangdian 区域,招待沉积的 PbZn 存款沿着 Yangtze Craton 在大陆人 orogenic 带的方面上在 extensional 盆被形成。与经典 MVT 存款相比,在 Kangdian 区域的 PbZn 存款属于 MVT 存款。这份报纸是重要的不仅因为招待沉积的 PbZn 的开始的解释扔而且因为利用大贱金属在大沉积目标区域扔。 | WANG Changming DENG Jun ZHANG Shouting XUE Chunji YANG Liqiang WANG Qingfei SUN Xiang | 2010 | Acta Geologica Sinica(English Edition)2010，84，6： | 33 |
| 3 | Seasonal variation of Microcystis in Lake Taihu and its relationships with environmental factors显示文摘In order to monitor the changes of Microcystis along with temporal and spatial variations, seasonal variation of Microcystis in Lake Taihu was investigated by 16S-23S rRNA internal transcribed spacer denaturing gradient gel electrophoresis (16S-23S rRNA-ITS DGGE) and microscopic evaluation. Samples were collected quarterly at four sites (River Mouth, Meiliang Bay, Cross Area, and Lake Center) from August 2006 to April 2007. Results showed that Microcystis dominated total phytoplankton abundance at the four sites in all seasons except winter. The average annual abundance of Microcystis was relatively high at River Mouth and Meiliang Bay, reaching 81.22 × 106 and 61.32 × 106 cells/L, respectively. For temporal variations, Shannon-Wiener diversity index (H ) according to DGGE profile revealed the richness of Microcystis in summer (H = 1.375 ± 0.034) and winter (H = 1.650 ± 0.032) was lower than that in spring (H = 2.078 ± 0.031) and autumn (H = 2.365 ± 0.032) (P < 0.05). While for spatial variations, the richness of Microcystis at River Mouth (H = 2.015 ± 0.074) was higher than at other sites during four seasons (P < 0.01). Very few dierences of Microcystis diversity in the same season were observed among the other three sites (P > 0.05). Canonical correspondence analysis (CCA) was performed to elucidate the relationships between Microcystis operational taxonomic units (OTUs) composition and the environmental factors. Results of CCA revealed that temperature was strongly positively correlated with the first axis (r = 0.963), while TSS was negative correlated with the second axis (r = -0.716). Phylogenetic tree based on the sequencing results of target bands on DGGE gel indicated that samples collected in summer and winter constituted two separated clusters. | TAN Xiao KONG Fanxiang ZENG Qingfei CAO Huansheng QIAN Shanqin ZHANG Min | 2009 | Journal of Environmental Sciences2009，21，7： | 16 |
| 4 | Multifractal Analysis of Element Distribution in Skarn-type Deposits in the Shizishan Orefield,Tongling Area,Anhui Province,China显示文摘与进不同 skarn 类型的大约 1000 m 扔的长度从四个练习核心取样的一系列元素集中从 Shizishan orefield 被选择,中央 Tongling,安徽的东南的部分省。用 multifractal 方法,专业和踪迹元素的分发和迁居特征被分析。而踪迹元素的光谱是扭曲权利的,主要元素的 multifractal 光谱是扭曲左的,它证明在 skarn 形成的过程,踪迹元素仅仅局部地被充实,并且主要元素在一个大得多的范围以内搬运。 multifractal 参数的关联系数一( multifractal 光谱的宽度)四项练习,核心是相对低的,但是 multifractal 参数 R (光谱对称参数)的关联系数和 f 相对更高,显示尽管元素的分发的非同类的紧张是不一致的,他们的空间累积模式是几乎一样在形成矿石的过程期间。在不同地点的各种各样的元素的 multifractal 参数的统计证明在 Shizishan orefield 的形成矿石的进程和元素移植模式是一致的,并且踪迹元素的迁居和主要元素展出一些差别。 | WANG Qingfei DENG Jun WAN Li ZHAO Jie GONG Qingjie YANG Liqiang ZHOU Lei ZHANG Zhijun | 2008 | Acta Geologica Sinica(English Edition)2008，82，4： | 8 |
| 5 | Understanding Urban Spatial Structure of Shanghai Central City Based on Mobile Phone Data显示文摘Taking Shanghai Central City as its case study, this paper presents an approach to exploring the urban spatial structure through mobile phone positioning data. Firstly, based on base station location data and mobile phone signaling data, the paper analyses the number of users connecting to each base station, and further generates the maps of mobile phone user density through kernel density analysis. We move on to calculate the multi-day average user density based on a time frame of 10:00 and 23:00 at workdays and 15:00 and 23:00 at weekends for Shanghai Central City. Then, through spatial aggregation and density classifi cation on the density maps of 10:00 at workdays and 15:00 at weekends, we identify the ranks and functions of public centers within Shanghai Central City. Lastly, we identify residential areas, business off ice areas, and leisure areas in Shanghai Central City and measure the degree of functional mix by comparing the ratio of day and night user density as well as the user density at nighttime of workdays and weekends. | Niu Xinyi Ding Liang Song Xiaodong Zhang Qingfei | 2015 | China City Planning Review2015，24，3： | 7 |
| 6 | The Formation of the Jiaodong Gold Province显示文摘Gold deposits in Jiaodong,termed Jiaodong-type,are tectonically located in the southeastern margin of the North China Craton.Their major features are reviewed in this paper to highlight the differences between Jiaodong deposits and other genetic types of gold deposits.The mineralization was synchronized with asthenosphere upwelling indicated by synore OIB-like mafic dike and large-scale crustal thinning suggested by decrease of Sr/Y from pre-ore to syn-ore granites.Asthenosphere upwelling induced by the roll-back of Paleo-Pacific Plate drove partial melting of lithospheric mantle and devolatilization,which induced the release of the ore-forming fluids.In concomitant with magmatic records,mineralization migrated from the western Jiaobei terrane(133–127 Ma)to the eastern Sulu orogenic belt(114–108 Ma),corresponding to the eastward roll-back of Paleo-Pacific Plate.Gold mineralization in Jiaodong formed in the transitions of ductile to brittle deformation,rapid to slow crustal uplift,and regional compression to extension.In the regional-scale,the gold deposits in the Jiaobei terrane are mostly situated at intersections between NE-trending faults and EW-trending basement faults,and gold orebodies dominantly controlled by the lithologic contacts between Precambrian metamorphic rocks and Mesozoic granites.The mineralization was dominated by the disseminated-veinlet ores related to quartz–sericite alteration in strong cataclasite-breccia zone,with subsidiary thick quartz-sulfide veins developed in secondary fault zones.The ore-forming fluids belong to a H_(2)O–CO_(2)–NaCl±CH_(4)system and show minor variations in salinity among different types of ore.Structure-fluid feedback involving fluid-rock reaction and hydrofracturing triggered the fluid phase separation and resultant gold deposition.The Jiaodong gold deposits are distinct from orogenic and intrusion-related gold deposits in terms of tectonic setting,origin of ore-forming fluids,and mechanism of gold deposition. | DENG Jun WANG Qingfei LIU Xuefei ZHANG Liang YANG Liqiang YANG Lin QIU Kunfeng GUO Linnan LIANG Yayun MA Yao | 2022 | Acta Geologica Sinica(English Edition)2022，96，6： | 7 |
| 7 | Influence of the Chuxiong Yao'an Earthquake on the Mineralization of Hot Springs in the Tengchong Geothermal Area,Southwestern China显示文摘Tengchong 地热的区域,有经常的地震的一个活跃构造区域,位于西南的中国的云南省。这个区域包含丰富的活跃温泉,它经常显示高金属集中和明显的矿化作用现象。在 19:19 在 2009 年 7 月 9 日,地震发生在 Yao'an, Chuxiong,云南省,它是到 Tengchong 地热的区域的东北的 300 km。我们从 7 月 4 日在 Tengchong 区域在温泉取样了水到 2009 年 7 月 9 日并且从 7 月 10 日到 2009 年 7 月 15 日在地震前后学习元素的集中的变化并且在温泉的矿化作用上讨论地震的影响。大多数踪迹元素的集中稍微增加了,但是 REE (稀土元素元素) 的集中在一个趋势 NS 差错附近在温泉在地震以后在 50% 减少了。元素的集中在 Longtan 和 Suanshuigou 仍然保持未改变,它与一个不活跃的坑有关。在表面、小规模的差错控制的另外的弹簧的元素的集中在地震以后减少了。地震能刺激深差错和岩浆房间的活动,作为为沿着趋势 NS 深差错的温泉的金属集中的增加负责;而它能减少可渗透的岩石的孔,在与表面的差错有关的温泉导致忍受矿石的液体和相应矿化作用的流动的衰落。 | DENG Jun XIAO Changhao WANG Qingfei ZHOU Xingzhi YANG Liqiang ZHANG Jing ZHAO Yan | 2010 | Acta Geologica Sinica(English Edition)2010，84，6： | 6 |
| 8 | Genome editing in Drosophila melanogaster: from basic genome engineering to the multipurpose CRISPR-Cas9 system显示文摘Nowadays, genome editing tools are indispensable for studying gene function in order to increase our knowledge of biochemical processes and disease mechanisms. The extensive availability of mutagenesis and transgenesis tools make Drosophila melanogaster an excellent model organism for geneticists. Early mutagenesis tools relied on chemical or physical methods,ethyl methane sulfonate(EMS) and X-rays respectively, to randomly alter DNA at a nucleotide or chromosomal level. Since the discovery of transposable elements and the availability of the complete fly genome, specific genome editing tools, such as P-elements, zinc-finger nucleases(ZFNs) and transcription activator-like effector nucleases(TALENs), have undergone rapid development. Currently, one of the leading and most effective contemporary tools is the CRISPR-cas9 system made popular because of its low cost, effectiveness, specificity and simplicity of use. This review briefly addresses the most commonly used mutagenesis and transgenesis tools in Drosophila, followed by an in-depth review of the multipurpose CRISPR-Cas9 system and its current applications. | Xingjie Ren Kristof Holsteens Haiyi Li Jin Sun Yifan Zhang Lu-Ping Liu Qingfei Liu Jian-Quan Ni | 2017 | Science China(Life Sciences)2017，60，5： | 5 |
| 9 | ^(40)Ar/^(39)Ar Dating of Xuebaoding Granite in the Songpan-Garze Orogenic Belt,Southwest China,and its Geological Significance显示文摘Thus far,our understanding of the emplacement of Xuebaoding granite and the occurrence and evolution of the Songpan-Garze Orogenic Belt has been complicated by differing age spectra results.Therefore,in this study,the ^(40)Ar/^(39)Ar and sensitive high resolution ion micro-probe(SHRIMP) U-Pb dating methods were both used and the results compared,particularly with respect to dating data for Pankou and Pukouling granites from Xuebaoding,to establish ages that are close to the real emplacements.The results of SHRIMP U-Pb dating for zircon showed a high amount of U,but a very low value for Th/U.The high U amount,coupled with characteristics of inclusions in zircons,indicates that Xuebaoding granites are not suitable for U-Pb dating.Therefore,muscovite in the same granite samples was selected for ^(40)Ar/^(39)Ar dating.The ^(40)Ar/^(39)Ar age spectrum obtained on bulk muscovite from Pukouling granite in the Xuebaoding,gave a plateau age of 200.1±1.2 Ma and an inverse isochron age of 200.6±1.2 Ma.The ^(40)Ar/^(39)Ar age spectrum obtained on bulk muscovite from Pankou granite in the Xuebaoding gave another plateau age of 193.4±1.1 Ma and an inverse isochron age of 193.7±1.1 Ma. The ^(40)Ar/^(36)Ar intercept of 277.0±23.4(2σ) was very close to the air ratio,indicating that no apparent excess argon contamination was present.These age dating spectra indicate that both granites were emplaced at 200.6±1.3 Ma and 193.7±1.1 Ma,respectively.Through comparison of both dating methods and their results,we can conclude that it is feasible that the muscovite in the granite bearing high U could be used for ^(40)Ar/^(39)Ar dating without extra Ar.Based on this evidence,as well as the geological characteristics of the Xuebaoding W-Sn-Be deposit and petrology of granites,it can be concluded that the material origin of the Xuebaoding W-Sn-Be deposit might partially originate from the Xuebaoding granite group emplacement at about 200 Ma.Moreover,compared with other granites and deposits distributed in various positions in the Songpan-Garze Orogenic Belt,the Xuebaoding emplacement ages further show that the main rare metal deposits and granites in peripheral regions occurred earlier than those in the inner Songpan-Garze.Therefore,^(40)Ar/^(39)Ar dating of Xuebaoding granite will lay a solid foundation for studying the occurrence and evolution of granite and rare earth element deposits in the Songpan-Garze Orogenic Belt. | LIU Yan DENG Jun ZHANG Guibin SHI Guanghai YANG Liqiang WANG Qingfei | 2010 | Acta Geologica Sinica(English Edition)2010，84，2： | 5 |
| 10 | Crucial control on magmatic-hydrothermal Sn deposit in the Tengchong block,SW China:Evidence from magma differentiation and zircon geochemistry显示文摘Magmatic-hydrothermal Sn deposits are commonly associated with high silica magmas,but why most global high silica granites do not bear economic Sn ore grades remains unclear.Two crucial factors controlling magmatic-hydrothermal Sn mineralization,including advanced fractionation and depressurization-induced rapid cooling,were revealed in the case study of the Guyong granitic pluton linked with the Xiaolonghe Sn deposit,in the Tengchong block,SW China.The Guyong granitic pluton comprises three petrological facies:less evolved biotite syenogranite,evolved alkali granite and leucogranite,and highly evolved facies(the protolith of greisenized granite).Similar crystallization ages(~77 Ma)and gradual contact between different petrological facies indicate the Guyong granitic pluton records a continuous fractionation process.Monte Carlo-revised Rayleigh fractionation model suggests the fractionation degree of the Guyong pluton is markedly high(>87 wt.%)that can only be achieved by a high initial water(≥4 wt.%)content in the parent granitic magma revealed by rhyolite-MELTS calculation.Advanced degree fractionation causes the first Sn enrichment but it also significantly increases the viscosity of evolved magmas,suppressing the exsolution and transport of hydrothermal fluids.Hence,it must be compensated by the second critical factor:depressurization-induced rapid cooling,reflected by the occurrence of highly metamict zircons in the greisenized granite.The highly metamict feature,indicated by the large full width at half maximum(FWHM)values of zirconν3(SiO_(4)) peak(>19.5 cm^(-1)),suggests these zircons do not experience thermal annealing but rapidly ascend into a shallow cooling environment.Depressurization-induced rapid cooling facilitates exsolution and transport of hydrothermal fluids,interacting with wall rocks and resulting in Sn mineralization. | Qiwei Zhang Qingfei Wang Gongjian Li Xiang Sun Qihai Shu Jun Deng | 2022 | Geoscience Frontiers2022，13，4： | 4 |
| 11 | Recognition of two contrasting structural-and mineralogical-gold mineral systems in the Youjiang basin,China-Vietnam:Orogenic gold in the south and Carlin-type in the north显示文摘The gold deposits in the Youjiang basin,totaling>25 Moz gold,have traditionally been thought to be of Carlin-type,particularly those with extensional structural geometries in the northern basin dominated by platform sedimentary sequences.However,the structural geometries,mineralization styles and alteration types for the Jinya,Gaolong and Nakuang gold deposits in the south-central part of the basin are remarkably similar to those of unequivocal orogenic gold deposits.Structural studies show that gold mineralization in the three gold deposits was controlled by tight“locked-up”anticlines with NW−SE-to E−W-trending and/or concomitant thrusts and/or shear zones,which resulted from NE−SW-to N–S-trending compression or transpression following the Early Triassic closure of the Paleo-Tethyan Ocean.Alteration zones in these deposits are dominated by silicification(quartz),sericitization,sulfidation and carbonation.Zoned pyrites in these deposits comprise Au-poor cores and invisible Au-bearing rims with minor external free gold.Euhedral to subhedral auriferous arsenopyrites also contribute to the gold budget.These features indicate that the three gold deposits are sediment-hosted orogenic gold deposits that contrast markedly with the Carlin-type gold deposits in the northern part of the Youjiang basin in terms of structural geometry and timing,mineralization style and nature of associated alteration.Although additional reliable ages using robust methodologies are still required,the older isotopic ages of the gold deposits in the south-central Youjiang basin are also consistent with earlier formation during transpression that predated extension during orogenic collapse,the period of formation of the Carlin-type gold deposits in the northern Youjiang basin. | Lin Yang Jun Deng David IGroves Qingfei Wang Liang Zhang Wei Wu Kai Qin Qizuan Zhang | 2020 | Geoscience Frontiers2020，11，5： | 3 |
| 12 | 玉湖完小,丽江,云南,中国显示文摘1背景
玉湖村,一个位于世界文化遗产保护基地丽江的纳西小村落,因玉湖而得名。玉湖是一个由玉龙雪山的冰川融化下来的水所形成的小湖泊。小村坐落在玉龙雪山脚下,宁静而幽美,海拔2760m,气候宜人,冬暖夏凉。美丽的雪山、晶莹的雪峰,为村落提供了一个壮观的背景。 | ZHANG Qingfei | 2014 | 世界建筑2014，，9： | 3 |
| 13 | Type III interferon-induced CBFβinhibits HBV replication by hijacking HBx显示文摘Hepatitis B virus(HBV)and its associated chronic infection remain serious health threats worldwide.However,there is still no impactful approach for clinical treatment of hepatitis B patients.Therefore,developing a better understanding of the interactions between HBV and its host is particularly important.HBV infection has been reported to induce type-III but not type-I or type-II interferon(IFN).In this study,we identified CBFβ,an HIV enhancer,as an HBV restriction factor that is specifically induced by type-III IFN in the early stages of HBV infection.Type-III IFN-induced IL-10 played an important role in the production of CBFβ.Interestingly,the interaction between CBFβ-and HBV-encoded regulatory protein X(HBx)enhanced the stability of CBFβ,but notably blocked HBx-mediated promotion of HBV replication.CBFβexpression was lower in HBV patients than in healthy persons,and the addition of serum from HBV patients inhibited CBFβexpression in HepG2 cells.On the contrary,HBV via HBsAg inhibited type-III IFN-induced CBFβexpression and decreased the anti-HBV activity of type-III IFN,suggesting that HBV inhibits antiviral interferon-stimulated gene(ISG)expression and induces IFN resistance.Collectively,our results demonstrate that type-III IFN-triggered and IL-10-induced CBFβare crucial factors for inhibiting HBV replication,and the HBx–CBFβ–HBsAg axis reveals a new molecular mechanism of interaction between HBV and its hosts. | Fengchao Xu Hongxiao Song Qingfei Xiao Na Li Hong Zhang Genhong Cheng Guangyun Tan | 2019 | Cellular & Molecular Immunology2019，16，4： | 3 |
| 14 | 3D uniform nitrogen-doped carbon skeleton for ultra-stable sodium metal anode显示文摘Sodium metal batteries are arousing extensive interest owing to their high energy density,low cost and wide resource.However,the practical development of sodium metal batteries is inherently plagued by the severe volume expansion and the dendrite growth of sodium metal anode during long cycles under high current density.Herein,a simple electrospinning method is applied to construct the uniformly nitrogen-doped porous carbon fiber skeleton and used as three-dimensional(3D)current collector for sodium metal anode,which has high specific surface area(1,098 m^2/g)and strong binding to sodium metal.As a result,nitrogen-doped carbon fiber current collector shows a low sodium deposition overpotential and a highly stable cyclability for 3,500 h with a high coulombic effciency of 99.9%at 2 mA/cm^2 and 2 mAh/cm^2.Moreover,the full cells using carbon coated sodium vanadium phosphate as cathode and sodium pre-plated nitrogen-doped carbon fiber skeleton as hybrid anode can stably cycle for 300 times.These results illustrate an effective strategy to construct a 3D uniformly nitrogen-doped carbon skeleton based sodium metal hybrid anode without the formation of dendrites,which provide a prospect for further development and research of high performance sodium metal batteries. | Ben Liu Danni Lei Jin Wang Qingfei Zhang Yinggan Zhang Wei He Hongfei Zheng Baisheng Sa Qingshui Xie Dong-Liang Peng Baihua Qu | 2020 | Nano Research2020，13，8： | 3 |
| 15 | Spatio-Temporal Changes of Population Density and Urbanization Pattern in China(2000–2010)显示文摘Population distribution and their temporal variation are a direct proxy of urbanization. This study evaluates the population density variation of China between 2000 and 2010 at the township level by using the data of the fi fth and sixth national population censuses. The urbanization patterns of China in 2000 and 2010 are depicted based on the population densities at various levels and the urbanization process of China between 2000 and 2010 is then analyzed through a comparative approach. It also tries to visualize the population density dynamics and urbanization pattern variations of China at the township level. | Mao Qizhi Long Ying Wu Kang Zhang Qingfei | 2016 | China City Planning Review2016，25，4： | 2 |
| 16 | Lithosphere architecture characterized by crust±mantle decoupling controls the formation of orogenic gold deposits显示文摘This study,via combined analysis of geophysical and geochemical data,reveals a lithospheric architecture characterized by crust-mantle decoupling and vertical heat-flow conduits that control orogenic gold mineralization in the Ailaoshan gold belt on the southeastern margin of Tibet.The mantle seismic tomography indicates that the crust-mantle decoupled deformation,defined from previous seismic anisotropy analysis,was formed by upwelling and lateral flow of the asthenosphere,driven by deep sub duction of the Indian continent,Our magnetotelluric and seismic images show both a vertical conductor across the Moho and high Vp/Vs anomalies both in the uppermost mantle and lowest crust,suggesting that crust-mantle decoupling promotes ponding of mantle-derived basic melts at the base of the crust via a heat-flow conduit.Noble gas isotope and halogen ratios of gold-related ore minerals indicate a mantle source of ore fluid.A rapid decrease in Cl/F ratios of lamprophyres under conditions of 1.2 GPa and1050℃suggests that the ore fluid was derived from degassing of the basic melts.Similar lithospheric architecture is recognized in other orogenic gold provinces,implying analogous formational controls. | Zengqian Hou Qingfei Wang Haijiang Zhang Bo Xu Nian Yu Rui Wang David IGroves Yuanchuan Zheng Shoucheng Han Lei Gao Lin Yang | 2023 | National Science Review2023，10，3： | 2 |
| 17 | Study on behaviors of functionally graded shape memory alloy cylinder显示文摘For better controllability in actuations,it is desirable to create Functionally Graded Shape Memory Alloys(FG-SMAs)in the actuation direction.It can be achieved by applying different heat treatment processes to create the gradient along the radius of a SMA cylinder.Analytical solutions are derived to predict the macroscopic behaviors of such a functionally graded SMA cylinder.The Tresca yield criterion and linear hardening are used to describe the different phase transformations with different gradient parameters.The numerical results for an example of the model exhibit different pseudo-elastic behaviors from the non-gradient case,as well as a variational hysteresis loop for the transformation,providing a mechanism for easy actuation control.When the gradient disappears,the model can degenerate to the non-gradient case. | Bingfei Liu Qingfei Wang Rui Zhou Chunzhi Du Yanan Zhang Pan Zhang | 2017 | Acta Mechanica Solida Sinica2017，30，6： | 2 |
| 18 | Metallogenetic model of Jiaodong-type gold deposits,eastern China显示文摘The genesis of giant gold provinces is an international scientific frontier,in which the source of a huge amount of gold and the drive for mineralization are key challenges.The mineralization intensity of the Jiaodong gold province in eastern China is a rare occasion in the world,because it owns gold reserves of~5500 tons within an area of less than 10,000 km^(2).The Jiaodong gold province formed in the superimposed domain of diverse tectonic regimes in an intracontinental setting.Paleoproterozoic regional peak metamorphism and Triassic continental collision are followed by the tectonic transition and gold mineralization at ca.120 Ma with time intervals of 1.9 billion years and about 100 million years,respectively.The Jiaodong gold deposits are different from orogenic and intrusion-related gold deposits in terms of the tectonic background,types of host rocks,and oreforming mechanism.These gold deposits show close spatial-temporal and genetic relationships to mafic igneous rocks,implying the derivation of ore-forming fluids from the metasomatic mantle domains.Mafic dykes in Jiaodong have negativeε_(Hf)(t)values of-29.9 to-9.1,Os content of 0.002-0.16 ppb,heavyδ^(18)O up to 8.23‰,and high initial^(187)Os/^(188)Os ratios of 0.1352-0.8858.These indicate that the lithospheric mantle was metasomatized by ancient crust-derived components.The lithospheric mantle in the western Jiaodong shows generally more enriched isotope features than that in the eastern part,which is explained to be an important reason for its huge gold resources.The mafic dykes show lighter Mg isotope characteristics(averageδ^(26)Mg of-0.33‰,n=50)and high Ca O content(overall greater than 6.5 wt%),indicating that the lithospheric mantle would also record the metasomatism by the carbonate rocks from the subducting oceanic slab.Under the background of the rollback of the subducting paleo-Pacific slab and the destruction of the North China Craton,partial melting of the lower crust would produce granitic magmas that led to the enrichment of gold in the residual crust.The syn-mineralization asthenosphere upwelling would promote the recycling of the lower crust and the partial melting of the metasomatic mantle domains.Basic magmas,produced by the partial melting,and the mantle itself would degas to form ore fluids.The ore fluids would further leach gold in the lower crust to increase its fertility.The auriferous fluids were transported to the middle to upper crust along the detachment and strike-slip faults.Water-rock interaction and fluid immiscibility,which occurred in and above the ductile-brittle transition zone to induce gold precipitation,formed the Jiaodong gold deposits.Given the unique geological features and genetic model of the Jiaodong gold deposits,they can be defined as“Jiaodong-type”gold deposits. | Jun DENG Qingfei WANG Liang ZHANG Shengchao XUE Xuefei LIU Lin YANG Liqiang YANG Kunfeng QIU Yayun LIANG | 2023 | Science China Earth Sciences2023，66，10： | 2 |
| 19 | Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors显示文摘组合指向的治疗在由堵住治疗癌症是更有效的绕过机制或导致的合成致命性。然而,他们的临床的申请被抵抗和毒性妨碍。遇见这重要挑战,我们用 ErbB2-overexpressing/PTEN-low 开发了并且测试各种各样的指向的治疗的指导 biomarker 的顺序的应用程序的一个新奇概念,高度好攻击的乳癌作为我们的模型。惊人地,从遗传上设计的鼠标与 intratumoral 异质从病人和乳房的肿瘤在两 PTEN-low/trastuzumab-resistant 乳癌支撑了 ErbB2 和下游的小径驱动器 trastuzumab 抵抗的激活。尽管 lapatinib 开始禁止了 trastuzumab 抵抗的鼠标肿瘤,肿瘤由激活表明由量的蛋白质数组出现的网络的 PI3K/mTOR 绕过抑制。有趣地,小径也是的 mTOR 的激活在 neoadjuvant 观察了表明 lapatinib 抵抗的对待 lapatinib 的病人。Trastuzumab + lapatinib 抵抗被一个 PI3K/mTOR 双 kinase 禁止者(BEZ235 ) 的顺序的申请有效地没有重要毒性克服。然而,我们的 p-RTK 数组分析证明 BEZ235 治疗在遗传上设计的老鼠肿瘤导致了增加的 ErbB2 表示和 phosphorylation,导致 BEZ235 抵抗并且在 3-D,然而并非 2-D,文化。机械学地,我们作为 BEZ235 抵抗的新奇机制识别了 ErbB2 蛋白质稳定和激活,它被随后的治疗与 lapatinib + BEZ235 联合颠倒。显著地, biomarker 指导的指向的治疗的这个顺序的应用程序在很快发展加倍的抵抗的肿瘤改变忍受极其好攻击的肿瘤的鼠标的寿命。使用的这条根本上新奇的途径有效地在一个顺序的顺序罐头指向了治疗目标和改编在在治疗期间发展抵抗的癌症的发信号的网络。 | Ozgur Sahin Qingfei Wang Samuel W Brady Kenneth Ellis Hai Wang Chia-Chi Chang Qingling Zhang Preety Priya Rui Zhu Stephen T Wong Melissa D Landis William J Muller Francisco J Esteva Jenny Chang Dihua Yu | 2014 | Cell Research2014，24，5： | 2 |
| 20 | Speed and Trend of China's Urbanization: A Comparative Study Based on Cross-Country Panel Data Model显示文摘This article investigates the speed and trend of urbanization in China and other countries by applying a non-linear model with panel data from 41 big countries with a population of over ten millions. It fi nds that the relationship between China's urbanization and economic development presents a less fl uctuating S-shaped curve which refl ects the variation in urbanization between China and other large countries. Calculated in line with the PPP(purchasing power parity) of 2009, China's rapid urbanization started when the GDP per capita reached 1,339 US dollars and the urbanization level was 22.92%, though lower than the world average by 5.16 percentage points. China's rapid urbanization ends when the GDP per capita reaches 12,088 US dollars and the urbanization level amounts to 50.69%, with the percentage lower than the world average by 16.32 percentage points. And China's urbanization will be completed when the GDP per capita climbs to 28,306 US dollars and the urbanization level reaches 61.55%, 12.32 percentage points lower than the world average then. Nevertheless, the unique background of China, including its socio-economic development, land institutional arrangements, and authoritarian political system, will have a great impact on the urbanization trend. Particularly, as China's socio-economic reform deepens, China's urbanization level will reach a new height. | Chen Ming Wang Kai Zhang Qingfei | 2015 | China City Planning Review2015，24，2： | 1 |
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