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39篇 您的检索式:作者名="ZHOU Yinghua"
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1Research advances in the Mesozoic tectonic regimes during the formation of Jiaodong ore cluster area显示文摘在诺思中国的东方区域在中生代时代在 Jiaodong 矿石簇区域和相关构造政体转变把构造政体的进展基于研究,在这篇论文,我们首先总结要求后面被学习的一些关键问题。然后,我们建议一条途径到处理这些问题。在 Jiaodong 矿石的金存款聚类区域,这被知道,它具有不同矿化作用式样,空间 istributions 和地质的背景,可能作为从在中生代的至少一个地质的事件的结果。到现在为止,特别在上述事件的 geodynamic 机制上,关于时间的进化和空间迁居顺序的这种研究是远非足够的。而且,描述行动模式和构造动态政体的时间空间的框架并且提出每构造动态政体的相对贡献因为 metallogensis 是静止的质问到地质学家在 Jiaodong 的形成上学习的份量上矿石簇区域。根据地区性的构造分析,结构的动力学,观察和矿化作用网络的探索的解释,我们建议有一些的一个 geological-physical-chemical 模型抑制从全面分析发源。我们然后使用这个模型模仿结构的变丑,热运输,液体流动和化学反应的联合过程。获得的结果显示模型在进一步在 Jiaodong 矿石簇区域并且在进一步理解集体 metallogensis 的性质分析构造政体的时间空间的进化小道是有效的。DENG Jun YANG Liqiang GE Liangsheng WANG Qingfei ZHANG Jing GAO Bangfei ZHOU Yinghua JIANG Shaoqing 2006Progress in Natural Science:Materials International2006,16,8:51
2Coupling Effects on Gold Mineralization of Deep and Shallow Structures in the Northwestern Jiaodong Peninsula, Eastern China显示文摘为在金矿化作用上理解可能的深层的过程和 geodynamicconstrains,全面物理化学并且金矿化作用的 geochemical 研究在这篇论文从 Jiaodong 半岛的西北的部分在 metallogenicepoch 期间在 paleo 岩石圈框架以内被承担了。尽管它被 post-metallogenictectonic 运动附加了并且改过, thepaleo 外壳的一幅一般图象被仍然是。金矿存款通常在本地人发生高举,坡度系上带子展示拐弯从对陡峭在花岗石变形的接触变质带轻轻,亲戚 Curler 等温的接口的坡度地区高举,等深线被等温线垂直地切的莫霍断绝和区域的消沉。金矿化作用和石版印刷开始被高温度,低压力和热流动的高力量描绘。从 0.8 ~ 4.5 km 的矿化作用范围的深度。在 metallogenic 时代的花岗石的建筑群的最高的接口的深度是大约 3 km。在有到 19.5 km 的深度结束的上地壳的底部有低速度的层(LVL ) ,它可以是在外壳中的一条分开带。LVL 的外观显示 paleo 过高热的液体的存在或熔融的岩浆储源的遗物,它反映在 diagenetic 和 metallogenic 时代和 Tanlu 断层带砍的走向滑倒的重叠效果期间的在外壳以内的部分融化。莫霍的沉淀可能被归因于在 NorthChina 和扬采·布洛克之间的 NW-SE 大陆碰撞的联合过程, Tanlu 差错的走向滑倒运动在 Jiaodong 半岛的西北的部分伴随了披风岩浆的 withunderplating。在披风的 plating 下面,岩浆可以导致部分融化并且向上做花岗石岩浆转移。这为 metallogenic 材料从的迁居是有利的对深对浅被充实形成存款。联合在 Tanlu 差错的走向滑倒之间的相互作用,在披风岩浆的 plating 下面,在外壳,和过高热的液体以内的部分融化,等等可以是在 metallogenic 系统控制金矿化作用和空间结构的重要因素。YANG Liqiang DENG Jun WANG Qingfei ZHOU Yinghua 2006Acta Geologica Sinica(English Edition)2006,80,3:42
3Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells显示文摘Spermatogonial 干细胞(SSC ) 能在移植以后生产众多的男配偶子进接受者睾丸,介绍为基因治疗和修改基因的动物的连续生产的一条珍贵途径。然而, SSC 的成功的基因操作被限制了,部分由于复杂性和当前可得到的基因编辑技术的低效率。这里,我们证明有效基因修正能用 CRISPR-Cas9 系统被介绍进 SSC。我们使用了 CRISPR-Cas9 系统变异在 SCC 的 EGFP transgene 或内长的 Crygc 基因。变异的 SSC 在移植以后经历了精子发生进不肥沃的老鼠睾丸的生精的小管。圆 spermatids 被产生并且在进成熟卵母细胞的注射以后,支持了显示相应变异的显型的异质接合的后代的生产。而且,在 Crygc 的一个引起疾病的变化(在 SSC 先存在的 Crygc −/−) 能乐意地到加入的 CRISPR-Cas9-induced nonhomologous 结束(NHEJ ) 或指导相同的修理(HDR ) 被修理,导致没有是的离开目标修正的证据带改正的基因的 SSC 线由整个染色体的定序出现。用从这些线产生的圆 spermatids 的授精在 100% 的效率与改正的显型产生了后代。我们的结果表明有效基因由 CRISPR-Cas9 系统在老鼠 SSC 编辑,并且提供在 SSC 经由基因修正治好基因疾病的原则的证明。Yuxuan Wu Hai Zhou Xiaoying Fan Ying Zhang Man Zhang Yinghua Wang Zhenfei Xie Meizhu Bai Qi Yin Dan Liang Wei Tang Jiaoyang Liao Chikai Zhou Wujuan Liu Ping Zhu Hongshan Guo Hong Pan Chunlian Wu Huijuan Shi Ligang Wu Fuchou Tang Jinsong Li 2015Cell Research2015,25,1:37
4Nickel accumulation and its effects on the survival rate of Spodoptera litura Fabricius under continuous nickel stress显示文摘The artificial diets mixed with various concentrations of nickel were offered to the larvae of the phytophagous insect Spodoptera litura Fabricius for 3 generations. Nickel accumulations in the 6th instar larvae, pupae and newly emerged adults of the corresponding generations of S. litura were investigated by Inductively Coupled Plasma-Atomic Emission Spectrometer (ICP-AES), and the effects of nickel accumulations on the survival rate of S. litura were also evaluated by individual rearing. The results showed that nickel accumulated in the 6th instar larvae, pupae and adults of S. litura, and the accu- mulated nickel in all the tested developmental stages within a generation increased with the increase of the nickel doses in the treated diets and showed significant dose-dependent relationship with the nickel doses in the artificial diets. The results also indicated that the nickel accumulations in the 6th instar larvae, pupae, and newly emerged adults from the 3rd generation were higher than those from the 2nd generation, which were also higher than those from the 1st generation. Nickel concentrations in pupae and adults were significantly lower than those in larvae, which indicated that the excessive nickel might be excreted during metamorphosis. Furthermore, larval survival rate, pupation rate and eclosion rate of S. litura in the tested three generations all decreased with the increase of the nickel doses in the treated diets.SUN HongXia SHU YingHua TANG WenCheng WANG Qi ZHOU Qiang ZHANG GuRen 2007Chinese Science Bulletin2007,52,14:16
5Effects of vegetation height and density on soil temperature variations显示文摘Reduction in vegetation cover caused by human activities has a great impact on soil temperature. It is important to assess how soil temperature responds to reduction of vegetation height and density. In this paper we first report the trends of mean annual soil surface and air temperatures recorded at the meteorological stations near the Ecological Research Station for Grassland Farming (ERSGF) from 1961 to 2007, then we setup an experiment using reed (Phragmites australis) stalks with different heights and densities to simulate effects of different vegetation height and density on soil and air temperatures. The warming rates of the mean annual soil and air temperatures were 0.043 and 0.041C a 1 , respectively. Changes of soil temperature were characterized by both increased mean annual maximum and minimum soil temperatures. At the experimental site, mean daily temperature, mean daily maximum soil and air temperatures increased significantly. In contrast, mean daily minimum soil temperature increased significantly while mean daily minimum air temperature decreased significantly as the height and density of reed stalks reduced during the experimental period. Mean diurnal soil temperature ranges were smaller than mean diurnal air temperature ranges. These results highlight that the importance of vegetation cover on soil and air temperatures.SONG YanTao ZHOU DaoWei ZHANG HongXiang LI GuangDi JIN YingHua LI Qiang 2013Chinese Science Bulletin2013,58,8:12
6Effects of fencing on vegetation and soil restoration in a degraded alkaline grassland in northeast China显示文摘In order to restore a degraded alkaline grassland, the local government implemented a large restoration project using fences in Changling county, Jilin province, China, in 2000. Grazing was excluded from the protected area, whereas the grazed area was continuously grazed at 8.5 dry sheep equivalent(DSE)/hm2. In the current research, soil and plant samples were taken from grazed and fenced areas to examine changes in vegetation and soil properties in 2005, 2006 and 2008. Results showed that vegetation characteristics and soil properties improved significantly in the fenced area compared with the grazed area. In the protected area the vegetation cover, height and above- and belowground biomass increased significantly. Soil pH, electrical conductivity and bulk density decreased significantly, but soil organic carbon and total nitrogen concentration increased greatly in the protected area. By comparing the vegetation and soil characteristics with pre-degraded grassland, we found that vegetation can recover 6 years after fencing, and soil pH can be restored 8 years after fencing. However, the restoration of soil organic carbon, total nitrogen and total phosphorus concentrations needed 16, 30 and 19 years, respectively. It is recommended that the stocking rate should be reduced to 1/3 of the current carrying capacity, or that a grazing regime of 1-year of grazing followed by a 2-year rest is adopted to sustain the current status of vegetation and soil resources. However, if N fertilizer is applied, the rest period could be shortened, depending on the rate of application.Qiang LI DaoWei ZHOU YingHua JIN MinLing WANG YanTao SONG GuangDi LI 2014Journal of Arid Land2014,6,4:9
7Late Paleozoic Fluid Systems and Their Ore-forming Effects in the Yuebei Basin,Northern Guangdong,China显示文摘Based on detailed and systematic researches of the geology of ore deposits, fluid inclusions and isotope geochemistry etc., and regarding the Late Paleozoic fluid system of the Yuebei Basin as an integrated object in this paper, we have revealed the temporo-spatial evolution law of the basin’s fluid system and discussed its ore-forming effects by simulating and analyzing the distribution of ore-forming elements, the fluid thermodynamics and dynamics of evolution processes of this basin. The results show that Late Paleozoic ore-forming fluid systems of the Yuebei Basin include four basic types as follows. (1) The sea floor volcanic-exhalation system developed during the rapid basin slip-extension stage in the Mid-Late Devonian, which affected the Dabaoshan region. It thus formed the Dabaoshan-type Cu-Pb-Zn-Fe sea floor volcanic-exhalation sedimentary deposits. (2) The compaction fluid system developed during the stable spreading and thermal subsidence-compression stage of the basin in the Mid-Late Devonian. The range of its effects extended all over the whole basin. It resulted in filling-metasomatic deposits, such as the Hongyan-type pyrite deposits and pyrite sheet within the Fankou-type Cu-Pb-Zn-S deposits. (3) The hot water circulation system of sea floor developed during the stage of basin uplifting and micro-aulacogen from the late Late Carboniferous to Middle Carboniferous. The range of its effects covered the Fankou region. It thus formed MVT deposits, such as the main orebody of the Fankou-type Pb-Zn-S deposits. (4) The gravity fluid system developed during the stage of fold uplifting and the basin closed from Middle Triassic to Jurassic, forming groundwater hydrothermal deposits, e.g. the veinlet Pb-Zn-calcite orebodies of the Fankou-type Pb-Zn-S deposits. Migration and concentration of the ore-forming fluids were constrained by the state of temporo-spatial distribution of its fluid potential. Growth faults not only converged the fluids and drove them to move upwards, but also the fluids often crossed the faults to the edges of the basin at the bottom of these faults and the lithologic interfaces, and even migrated to the basin’s edges from top to bottom along the faults, which may be one of the basic reasons for the stratabound deposits to cluster mainly along the contemporaneous faults on the inner border of the basin. The superposed mineralization resulting from the multi-stage activity of contemporaneous faults and ore-forming fluid systems in the basin may be one of the key factors for forming superlarge ore deposits.DENG Jun YANG Liqiang SUN Zhongshi WANG Jianping WANG Qingfei CHENG Xueming ZHOU Yinghua 2005Acta Geologica Sinica(English Edition)2005,79,5:6
8Effects of dietary nickel on detoxification enzyme activities in the midgut of Spodoptera litura Fabricius larvae显示文摘Nickel accumulated in midugt of Spodoptera litura Fabricius could induce the expression of metal-lothionein,one of the most important detoxification proteins in organisms.In the present study,the effects of dietary nickel on the activities of detoxification enzymes,such as carboxylesterase(CarE) and glutathione S-transferase(GST) in the midgut of S.litura larvae have been studied to get an un-derstanding of the detoxification mechanisms of S.litura larvae to excessive nickel.Results showed that CarE activities in the midgut of the 5th instar larvae decreased at lower levels of nickel(≤5 mg/kg),while increased with increasing nickel doses at higher levels of nickel(≥10 mg/kg) exposure in suc-cessive 3 generations.CarE activities of the 6th instar larvae were also characterized as inhibited at low levels of nickel exposure,and improved at higher levels in the 1st generation.CarE activities of 6th instar larvae in the 2nd and 3rd generations were all lower than that in control.However,GST activities in the midgut of the 5th and 6th instar larvae all increased with increasing nickel doses(1―20 mg/kg) in diets.SUN HongXia ZHOU Qiang TANG WenCheng SHU YingHua ZHANG GuRen 2008Chinese Science Bulletin2008,53,21:5
9System-Level EMC Assessment for Military Vehicular Communication Systems Based on a Modified Four-Level Assessment Model显示文摘With the development of EMC technology, EMC assessment has become increasingly important in EMC design. Although numerous EMC assessment models are available today, few of them can provide a tradeoff between efficiency and accuracy for the specific case of military vehicular communication systems. Face to this situation, a modified four-level assessment model is proposed in the paper. First, the development of EMC assessment technology is briefly reviewed, and the theoretical mechanism of EMI environment is introduced. Then, the architecture of the proposed model is outlined, and the assessment methods are explored. To demonstrate the application of it, an example involving a communication system in a military vehicle is presented. From the physical layer to the signal layer, a hierarchical assessment on the entire system is successfully performed based on the proposed model, and we can make a qualitative EMC assessment on the EMC performance of the system. Based on a comparison with the traditional model, we conclude that the proposed model is more accurate, more efficient and less time-consuming, which is suitable for the EMC assessment on militaryvehicular communication systems. We hope that the proposed model will serve as a useful reference for system-level EMC assessments for other systems.Ping Zhou Yinghua Lv Zhihong Chen Hongping Xu 2018China Communications2018,15,8:5
10Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting.Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu 2021Cancer Communications2021,41,9:5
11Cyanobacteria-based near-infrared light-excited self-supplying oxygen system for enhanced photodynamic therapy of hypoxic tumors显示文摘Tumor hypoxia has been considered to induce tumor cell resistance to radiotherapy and anticancer chemotherapy,as well as predisposing for increased tumor metastases.Therefore,strategies for the eradication of the hypoxic tumor are highly desirable.Photodynamic therapy(PDT)is a new technique that can be used to treat tumors using laser irradiation to photochemically activate a photosensitizer.Compared to traditional radiotherapy and chemotherapy,photodynamic therapy has many advantages,such as good selectivity,low toxicity,and less trauma and resistance.However,PDT is oxygen-dependent,and the lack of oxygen in hypoxic tumors renders photodynamic therapy ineffective.Cyanobacteria,the earliest photosynthetic oxygen-generating organisms,can utilize water as an electron donor to reduce CO_(2) into organic carbon compounds along with continuously releasing oxygen under sunlight.Inspired by this,herein,cyanobacteria were used as a living carrier of photosensitizer conjugated upconversion nanoparticles(UCNP)to construct a self-supplying oxygen PDT system.Improvement in the PDT efficiency for hypoxic tumors can be achieved as a result of in situ oxygen production by cyanobacteria under near-infrared(NIR)light using UCNP as a light harvesting antenna.A successful demonstration of this concept would be of great significance and could open the door to a new generation of carrier systems in the field of hypoxia-targeted drug transport platforms.Yinghua Zhang Huifang Liu Xinyue Dai Hang Li Xiaohan Zhou Shizhu Chen Jinchao Zhang Xing-Jie Liang Zhenhua Li 2021Nano Research2021,14,3:4
12Growth,nutritional quality,and energy use efficiency in two lettuce cultivars as influenced by white plus red versus red plus blue LEDs显示文摘Red plus blue light-emitting diodes(LEDs)are commonly applied in plant factories with artificial lighting due to photosynthetic pigments,which absorb strongly in red and blue light regions of the spectrum.However,plants grown under natural environment are used to utilizing broad-wide spectrum by long-term evolution.In order to examine the effects of addition light added in red plus blue LEDs or white LEDs,green and purple leaf lettuces(Lactuca sativa L.cv.Lvdie and Ziya)were hydroponically cultivated for 20 days under white LEDs,white plus red LEDs,red plus blue LEDs,and red plus blue LEDs supplemented with ultraviolet,green or far-red light,respectively.The results indicated that the addition of far-red light in red plus blue LEDs increased leaf fresh and dry weights of green leaf lettuce by 28%and 34%,respectively.Addition of ultraviolet light did not induce any differences in growth and energy use efficiency in both lettuce cultivars,while supplementing green light with red plus blue LEDs reduced the vitamin C content of green leaf lettuce by 44%and anthocyanin content of purple leaf lettuce by 30%compared with red plus blue LEDs,respectively.Spectral absorbencies of purple leaf lettuce grown under red plus blue LEDs supplemented with green light were lower in green light region compared with those grown under red plus blue LEDs,which was associated with anthocyanin contents.White plus red LEDs significantly increased leaf fresh and dry weights of purple leaf lettuce by 25%,and no significant differences were observed in vitamin C and nitrate contents compared with white LEDs.Fresh weight,light and electrical energy use efficiencies of hydroponic green and purple leaf lettuces grown under white plus red LEDs were higher or no significant differences compared with those grown under red plus blue LEDs.In conclusion,white plus red LEDs were suggested to substitute for red plus blue LEDs in hydroponic lettuce(cv.Lvdie and Ziya)production in plant factories with artificial lighting.Zhengnan Yan Dongxian He Genhua Niu Qing Zhou Yinghua Qu 2020International Journal of Agricultural and Biological Engineering2020,13,2:4
13Metallothionein expression induced by nickel accumulation in the midgut of Spodoptera litura Fabricius larvae exposed to nickel显示文摘Metallothionein expression induced by nickel accumulation in the midgut of Spodoptera litura Fabri- cius larvae was investigated by exposing S. litura larvae to the artificial diets amended with different doses of nickel for 3 generations. Nickel accumulations in the midgut of 6th instar larvae were detected by Inductively Coupled Plasma-Atomic Emission Spectrometer (ICP-AES), and the induced metal- lothionein expression in the midgut of 5th and 6th instar larvae in 120 h were quantified using cad- mium-hemoglobin total saturation methods. The accumulated nickel in the midgut of the 6th instar larvae within a generation increased with the increase of the nickel doses in the treated diets and showed significant dose-dependence with the nickel doses in diets. Metallothioneins induced by nickel accumulated in the larval midgut also increased with nickel doses in diets and with the increasing stressing time in a generation. Results also suggested that the metallothionein expression was differ- ent with the time of S. litura larvae stressed by nickel.SUN HongXia ZHOU Qiang TANG WenCheng SHU YingHua ZOU ZhiWen ZHANG GuRent 2007Chinese Science Bulletin2007,52,23:4
14Simulation analysis on co-site interference of vehicular digital communication system based on IM prediction method by BER显示文摘The co-site interference exists in kinds of communication systems, especially in digital communication systems, also is one of the biggest threats in electromagnetic compatibility(EMC) designation of the systems. Analyzing the co-site interference is an important process in achieving EMC performance of the system. Under the situation, the co-site interference simulation analysis of a vehicular digital communication system based on interference margin(IM) prediction method by bit error ratio(BER) was proposed in the paper. In the simulation analysis, some physical models of the vehicular communication system were established on SIMULINK environment, the upper limit of BER level for audio signals was defined as the IM, three different types of co-site interference was analyzed respectively, and the simulation results were obtained in the form of system interference bandwidth. From these results, the EMC performance evaluation of the vehicular communication system was predicted based on the IM prediction method. By comparing with the actual test results, the correctness of the simulation results was validated and the simulation analysis method can be used for reference by other communication systems was indicated.Zhou Ping Lu Yinghua Tao Yong Xu Hongping 2016The Journal of China Universities of Posts and Telecommunications2016,23,1:4
15A stringent dual control system overseeing transcription and activity of the Cre recombinase for the liver-specific conditional gene knock-out mouse model显示文摘Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with several unknown details. However, unlike in other tissues, a tis-sue specific inducible Cre recombinase system that allows temporal and spatial deletion of a target DNA fragment is still not available for in vivo functional gene annotation in hepatocytes. In our pursuit to establish such a mouse model, we designed a dual inducible Cre transgene system and tested it in cultured cells. By combining a CCAAT/enhancer binding protein β (C/EBP β) promoter derived Tet-off expression system and the estrogen receptor (ER) mediated functional control, we show a desirable profile of both hepatocyte-specificity and regulability of the Cre expression in a series of critical assessments in the cell culture system, which provides confidence in continua-tion of our ongoing pursuit in mouse.Yu Wu Yinghua He Hongyu Zhang Xinlan Dai Xiaoyu Zhou Jun Gu Guan Wang Jingde Zhu 2008Journal of Genetics and Genomics2008,35,7:3
16Coal and gas outburst prevention using new high water content cement slurry for injection into the coal seam显示文摘As coal and gas outburst is one of the most serious mine disasters, it is very important to at least control it if not prevent it from occurring. Injecting cement slurry or grouting into the coal seam can strengthen the seam, increase its rigidity coefficient(f), and reduce the volumetric expansion due to gas energy release.This paper reports the results of laboratory experiments on cement-based high water content slurry having different water-cement ratios(W/C) to be used for coal injection. The results show that as the W/C increases, the mobility of the slurry and its setting time increase. The compressive strength and rupture strength, however, are reduced. Furthermore, high W/C grout shows early strength after 7 days, which can be 80% of its 14-day compressive strength. To achieve rapid setting and early strength, the addition of Na_2SiO_3has proven to give the best result, when the concentration of the additive is 3%. The initial and final setting times are 13 and 21 min shorter than samples without Na_2SiO_3, while the compressive strength is more than double. As a retarder, the initial setting time can be extended to 83 min when tartaric acid of 0.4% concentration is added. Through the orthogonal experiment, the optimum recipe of the new high water content slurry has been determined to be: W/C = 2, tartaric acid = 0.2%, Na_2SiO_3= 3%, and12% bentonite. Reinforcement by injection simulation experiments show that the grouting radius of the new slurry mix is 250 mm when the applied grouting pressure is 60 k Pa, 7-day rupture strength and compressive strength are 5.2 and 6.4 MPa, respectively, and are 37% and 88% higher than ordinary cement grout. It can be concluded that the newly developed slurry mix is more effective than the ordinary mix for reinforcing coal and controlling gas outburst.Zhou Peiling Zhang Yinghua Huang Zhi'an Gao Yukun Wang Hui Luo Qiang 2017International Journal of Mining Science and Technology2017,27,4:3
17Experimental study on methane dissolved in surfactant-alkane system显示文摘A surfactant-polyalkane system is investigated using chemical reagents to dissolve methane and control coal seam gas from low-energy,high-efficiency,safety,and environmental protection perspectives.At different temperatures and pressures,a high-temperature and high-pressure reactor,gas chromatograph,and other related experimental equipment were used to perform methane dissolution experiments,and a single surfactant sodium oleate(NaOA)and n-hexane demonstrated superior results.The single-factor experiments of temperature,pressure,and NaOA addition were performed and fitted via a response surface analysis.The optimal conditions for methane solubility were as follows:temperature of 34C,pressure of 4.5 MPa,NaOA addition of 85 g/L,and time of 1 h.The optimal effect of the surfactant-polyalkane system in dissolving methane was achieved with 32.31 mL/100 mL.Meanwhile,the change in the surface structure of coal before and after washing with the system was compared using scanning electron microscopy.The results indicated that the gas after washing with the surfactant-polyalkane system dissolved,and the surface pore structure of the coal changed.Moreover,the specific surface area and pore size of the coal surface increased after washing.Hence,the desorption of gas from the coal surface into the system becomes easy,thereby reducing the gas content in the coal sample.Zhian Huang Mingli Chen Jingjing Wang Yinghua Zhang Linghua Zhang Hui Wang Yukun Gao Yupeng Zhou 2020International Journal of Mining Science and Technology2020,30,6:2
18Lead exposure improves the tolerance of Spodoptera litura (Lepidoptera: Noctuidae) to cypermethrin显示文摘Jialiang Zhou Yinghua Shu Guren Zhang Qiang Zhou 2012Chemosphere2012,,4:1
19An improved method of hash table based on transform and conquer 显示文摘Gan Wei Zhou Yinghua 2012Information and Com- putational Science2012,9,17:1
20Numerical simulation and experiment validation on lightning-induced effects of a special vehicle显示文摘In recent years, with the development of the system integration technology, the outside integrative special vehicles, such as big oil tank, trucks loading with dangerous goods and so on, are becoming more and more important. When the vehicle is under way, it will inevitably encounter the nature environment, including lightning. If the lightning strikes directly or very close to the vehicle, the lightning-induced effects will be very destructive. Therefore, for a better understanding of the lightning-induced effects produced on the special vehicle by the lightning strike, the research on lightning-induced effects of a special vehicle for aerospace system transportation was proposed. In the paper, a numerical simulation model for the special vehicle is established, the lightning-induced effects are analyzed successfully by using tramsmission-line matrix(TLM) algorithm, and the experiment validation example is also implemented. By comparing the numerical simulation with the actual experiment results, the correctness trend of the numerical simulation is validated and a mass of invaluable research data is obtained, which has a deep significance on the lightning research in our country.Zhou Ping Lv Yinghua Tao Yong Xu Hongping 2016The Journal of China Universities of Posts and Telecommunications2016,23,3:1
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