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| 1 | Interplay between the Indonesian Throughflow and the South China Sea Throughflow显示文摘Analysis both based on the wind stress and ocean assimilation dataset shows that the interannual variability of the Indonesian Throughflow and the South China Sea (Luzon Strait) Throughflow is out of phase. Wind anomaly forcing in the equatorial Pacific plays an important role in setting up this phase relation. During El Ni o events, the westerly wind bursts intensify the Northern Equator Current and induce a northward shift of its bifurcation point. As a result, the partition of volume transport between the Kuroshio and the Mindanao Current is changed, with the Kuroshio transport decreased and the Mindanao Current increased. The undershooting/overshooting phenomena occur at the Luzon Strait and the Sulawesi-Mindanao passage, caused by variability of these two currents. Water transport from the Pacific to the South China Sea increases with the Kuroshio transport decreased, and transport from the Pacific to the Indian Ocean decreases with the Mindanao Current transport increased. The situation is reversed during La Ni a. Therefore, the ocean dynamic meaning is profound to study the interannual variability relationship between the Indonesian Throughflow and the Luzon Strait Throughflow. | LIU Qinyan HUANG Ruixin WANG Dongxiao XIE Qiang HUANG Qizhou | 2006 | Chinese Science Bulletin2006，51，B12： | 24 |
| 2 | A novel class of tRNA-derived small RNAs extremely en- riched in mature mouse sperm显示文摘 | HongyingPeng JunchaoShi YingZhang HeZhang ShangyingLiao WeiLi LiLei ChunshengHan LinaNing YujingCao QiZhou QiChen EnkuiDuan | 2012 | Cell Research2012，22，11： | 20 |
| 3 | Association of vitamin D receptor and estrogen receptor-αgene polymorphism with peak bone mass and bone size in Chinese women显示文摘AIM: To investigate if vitamin D receptor (VDR) gene Apa I polymorphism and estrogen receptor-α (ER-α) gene Pvu II, Xba I polymorphisms are related to bone mineral density (BMD), bone mineral content (BMC) and bone size in premenopausal Chinese women. METHODS: The VDR Apa I genotype and ER-α Pvu II, Xba I genotype were determined by PCR-restriction fragment length polymorphism (RFLP) in 493 unrelated healthy women aged 20-40 years of Han nationality in Shanghai city. BMD (g/cm2), BMC (g), and bone areal size (BAS, cm2) at lumbar spine 1-4 (L1-4) and proximal femur (femoral neck, trochanter and Ward’s triangle) were measured by duel-energy X-ray absorptionmetry. RESULTS: All allele frequencies did not deviate from Hardy-Weinberg equilibrium. After pheno- types were adjusted for age, height, and weight, a significant association was found between VDR Apa I genotype and BMC variation at L1-4and Ward’s triangle (P<0.05), but not in BMD or BAS at lumbar spine and proximal femur. ER-α Pvu II, Xba I genotype was not related to BMC, BMD, and BAS at all sites. CONCLUSION: The study suggested that Apa I polymorphism in VDR gene may influence on attainment and maintenance of peak bone mass in premenopausal Chinese women. | Yue-juanQIN Zhen-linZHANG Qi-renHUANG Jin-weiHE Yun-qiuHU QiZHOU Jing-huiLU MiaoLI Yu-juanLIU | 2004 | Acta Pharmacologica Sinica2004，25，4： | 18 |
| 4 | Association of estrogen receptor-alpha and vitamin D receptor genotypes with therapeutic response to calcium in postmenopausal Chinese women显示文摘AIM: To investigate the correlation between calcium treatment in postmenopausal women and estrogen receptor- alpha (ER-alpha) Xba I and Pvu II genotype and vitamin D receptor (VDR) Apa I genotype. METHODS: One hundred fifteen postmenopausal Chinese women of Han population were enrolled and treated with calcichew-D3 (1000 mg calcium and 400 U vitamin D3) daily for 1 year. At entry and after 1 year treatment, the bone mineral density (BMD), serum and urinary bone turnover biochemical markers were evaluated. ER-alpha and VDR geno- type were analyzed using PCR-restriction fragment length polymorphism. RESULTS: After 1 year of calcium supplementation, a significant increase of BMD and a marked reduction in serum ALP and PTH levels, and a significant increase of serum 25-(OH) vitamin D level were observed (P<0.01 or P<0.05). At entry and after 1 year of treatment, no significant association was found between Xba I, Pvu II, and Apa I genotypes and BMD in L1-4, Neck, and Troch, and all bone turnover marker levels. However, the percentage of change (median, QR) in Neck BMD was significantly different in homozygous XX [-4.14 (from -6.54 to -1.34)] in comparison with Xx [1.72 (from -1.12 to 3.20)] (P<0.001) or xx [1.22 (from -1.74 to 3.06)] Xba I ER-alpha genotype (P=0.001). CONCLUSION: Women with ER-α Xba I genotype XX may have a higher risk of relatively fast bone mass loss in femoral neck after menopause and that they may have a poor responsiveness to calcium supplementation. The changes in BMD are not associated with ER-alpha Pvu II genotype and VDR Apa I genotype after 1 year of calcium supplementation. | Zhen-linZHANG Yue-juanQIN Qi-renHUANG Jin-weiHE MiaoLI QiZHOU Yun-qiuHU Yu-juanLIU | 2004 | Acta Pharmacologica Sinica2004，25，12： | 14 |
| 5 | Recent development of ductile cast iron production technology in China显示文摘Recent progress in the production and technology of ductile cast iron castings in China is reviewed. The manufacture and process control of as-cast ductile iron are discussed. The microstructure, properties and application of partial austenitization normalizing ductile iron and austempered ductile iron (ADI) are briefly depicted. The new development of ductile iron production techniques, such as cored-wire injection (wire-feeding nodularization) process, tundish cover ladle nodularizing process, horizontal continuous casting, and EPC process (lost foam) for ductile iron castings, etc., are summarized. | Cai Qizhou Wei Bokang | 2008 | China Foundry2008，5，2： | 13 |
| 6 | A novel advanced oxidation process——wet electrocatalytic oxidation for high concentrated organic wastewater treatment显示文摘A novel advanced oxidation process——wet electrocatalytic oxidation (WEO) was studied with p-nitrophenol as model pollutant and β-PbO2 electrode as the anode. Compared with the effect of the individual wet air oxidation (WAO) and electrochemical oxidation (EO), the effect of WEO showed syn- ergistic effect on COD removal under the conditions of temperature 160℃, C=1000 mg·L-1, PN2=0.50 MPa, PO2=0.9 MPa, current density = 3 mA·cm-2, Na2SO4 3 g·L-1. And the synergistic factor got the best value of 0.98 within 120 min after 180 min treatment. The synergistic factor was studied after 120 min treatment at 100℃, 120℃, 140℃ and 160℃, and the effect of 120℃ was the best with the value of 1.26. Possible mechanism for the synergistic effect was discussed based on the analysis of free-radical generation and intermediates detected by HPLC and GC/MS. | DAI QiZhou ZHOU MingHua LEI LeCheng ZHANG XingWang | 2007 | Chinese Science Bulletin2007，52，12： | 11 |
| 7 | Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis显示文摘 | ManTong ZhuoLv LeiLiu HuiZhu Qin-YuanZheng Xiao-YangZhao WeiLi Yi-BoWu Hai-JiangZhang Hua-JunWu Zhi-KunLi FanyiZeng LiuWang Xiu-JieWang Jia-HaoSha QiZhou | 2011 | Cell Research2011，21，11： | 11 |
| 8 | MRS and diffusion tensor image in mild traumatic brain injuries显示文摘Objective:To analyze characters of magnetic resonance spectroscopy(MRS) and diffusion tensor imaging(DTI) in the diagnosis of mild trauma brain injuries(MTBI) in frontal lobe and to compare with conventional magnetic resonance imaging(MRI).Methods:A total of 21 patients were selected,who all aged 12-51 years old and had injury within 24 hours.Computer tomography (CT) and the Glasgow Coma Scale were used to evaluate the degree of injury.All patients were diagnosed as MTBI,and 19 had conventional MRI,MRS and DTI.The major parameters of MRS were Probe-P sequence,TE= 144 or 35 ms,and both single voxel spectrum and chemical shift imging were included.The major parameters of DTI were diffusion directions =15,b value = 1000 s/mm^2. Frational anisotropic(FA) map and average ADC map were obtained to evaluate DTI result. Positive deletion ratio was observed and the imaging changes were compared between injured side and normal side.Results:All 21 patients had CT scan and Glasgow scale.A total of 19 patients had conventional MRI.DTI and MRS.Results of CT and conventional MRI showed no significant abnormality in lobe,and Glasgow scale showed mild type.MRS result showed significant decrease in N-acetyl aspartate(NAA) and NAA/creatine(Cr) in 13 cases(68.4%) (P<0.001),and increase in lactic acid(Lac) in 7 cases(36.8%).FA mapping of the frontal lobe displayed significant changes in 7 cases(36.8%),with 5 out of the 7 cases having increase in FA value.And there was no significant difference in average ADC.Conclusions:MRS and DTI might be more sensible than other methods,such as CT and conventional MRI in diagnosis of MTBI.The particular changes were reduced NAA and increased Lac for MRS.and increased FA values for DTI. | Jing Chen Hu Jin Ying Zhang Qizhou Liang Haiyan Liao Ziyi Guo Xiangjun Han | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，1： | 6 |
| 9 | The mini player with diverse functions:extracellular vesicles in cell biology,disease,and therapeutics显示文摘Extracellular vesicles(EVs)are tiny biological nanovesicles ranging from approximately 30–1000 nm in diameter that are released into the extracellular matrix of most cell types and in biofluids.The classification of EVs includes exosomes,microvesicles,and apoptotic bodies,dependent on various factors such as size,markers,and biogenesis pathways.The transition of EV relevance from that of being assumed as a trash bag to be a key player in critical physiological and pathological conditions has been revolutionary in many ways.EVs have been recently revealed to play a crucial role in stem cell biology and cancer progression via intercellular communication,contributing to organ development and the progression of cancer.This review focuses on the significant research progress made so far in the role of the crosstalk between EVs and stem cells and their niche,and cellular communication among different germ layers in developmental biology.In addition,it discusses the role of EVs in cancer progression and their application as therapeutic agents or drug delivery vehicles.All such discoveries have been facilitated by tremendous technological advancements in EV-associated research,especially the microfluidics systems.Their pros and cons in the context of characterization of EVs are also extensively discussed in this review.This review also deliberates the role of EVs in normal cell processes and disease conditions,and their application as a diagnostic and therapeutic tool.Finally,we propose future perspectives for EV-related research in stem cell and cancer biology. | Abhimanyu Thakur Xiaoshan Ke Ya-Wen Chen Pedram Motallebnejad Kui Zhang Qizhou Lian Huanhuan Joyce Chen | 2022 | Protein & Cell2022，13，9： | 3 |
| 10 | Claudin 6: a novel surface marker for characterizing mouse pluripotent stem cells显示文摘 | LinlinWang YanXue YihangShen WeiLi YanCheng XiaoshuangYan WanshengShi JuanWang ZhijuanGong GuanhengYang ChuanliangGuo YiyeZhou XiangWang QiZhou FanyiZeng | 2012 | Cell Research2012，22，6： | 2 |
| 11 | Toughening of epoxy resin blended with thermotropic hydroxyethyl cellulose acetate显示文摘 | Dai Qizhou Chen Jinming Huang Yong | 1998 | Journal of Applied Polymer Science1998，70，6： | 1 |
| 12 | Failure analysis of the impeller of slurry pump used in zinc hydrometallurgy process显示文摘 | Li Ping Cai Qizhou Wei Bokang | | 0，，06： | 1 |
| 13 | Natural disaster warning system for safe operation of a high-speed railway显示文摘In this paper,the least square support vector machine(LSSVM)is used to study the safety of a high-speed railway.According to the principle of LSSVM regression prediction,the parameters of the LSSVM are optimized to model the natural disaster early warning of safe operation of a high-speed railway,and the management measures and methods of high-speed railway safety operation under natural disasters are given.The relevant statistical data of China’s high-speed railway are used for training and verification.The experimental results show that the LSSVM can well reflect the nonlinear relationship between the accident rate and the influencing factors,with high simulation accuracy and strong generalization ability,and can effectively predict the natural disasters in the safe operation of a high-speed railway.Moreover,the early warning system can improve the ability of safety operation evaluation and early warning of high-speed railway under natural disasters,realize the development goals of high-speed railway(safety,speed,economic,low-carbon and environmental protection)and provide a theoretical basis and technical support for improving the safety of a high-speed railway. | Hu Qizhou Fang Xin Bian Lishuang | 2021 | Transportation Safety and Environment2021，3，4： | 1 |
| 14 | Three-dimensional numerical model study of the residual current in the South China Sea显示文摘 | Cai Shuqun Huang Qizhou Long Xiao min | 2003 | Oceanologica Acta2003，26，56： | 1 |
| 15 | Effect of (NaPO3)6 concentrations on corrosion resistance of plasma electrolytic oxidation coatings formed on AZ91D magnesium alloy显示文摘 | Haihe Luo Qizhou Cai Bokang Wei | 2008 | Journal of Alloys and Compounds2008，464，12： | 1 |
| 16 | Ozonation catalyzed by ceri- um supported on activated carbon for the degradation of typical pharmaceutical wastewater 显示文摘 | Dai Qizhou Wang Jiayu Chen Jun | 2014 | Separation and Purification Techno- logy2014，127，： | 1 |
| 17 | Long life modified lead dioxide anode for organic wastewater treatment: electrochemical characteristics and degradation mechanism显示文摘 | ZHOU Minghua DAI Qizhou | 2005 | Environ Sci Technol2005，39，： | 1 |
| 18 | Effects of Graphite Nodule Diameter on the Water Embrittlement Behavior of Austempered Ductile Iron 显示文摘 | Wei Bokang Tanaka Y | | J of Iron & Steel Res Int0，，： | 1 |
| 19 | Stock Returns, Volatility, and Cointegration among Chinese Stock Markets显示文摘This paper examines stockreturns, volatility, and cointegration among three Chinese stock marketsbeforeand afterHong Kong’sreturn to China. Theaverage daily returnsaremuch higherduring the first sub-period (from April1991 to June1997)and significantlyloweror even negativeduring the second sub-period (from July1997 to December2002). The mean adjusted changein volatilityis negativelyand significantly correlated with thelagged returns. This negative relation is mainly caused by a contemporaneous and significantly positive correlation between returnsand volatilityinthe firstsub-period. Thissignificant relationship disappears forthe Shanghai and Shenzhen Stock Exchanges and is even negative for the Hong Kong Stock Exchange during the second sub-period. Three Chinese stock markets arecointegrated over the entiresampleperiod and becomemore closelyrelated after Hong Kong’s return to China. Our results have important implications for both policy makers and individual investors. | QiZhou ZhongguoZhou | 2005 | China & World Economy2005，13，2： | 1 |
| 20 | Generating mESC-derived insulin-producing cell lines through an intermediate lineage-restricted progenitor line显示文摘 | GuoDong Li Ruihua Luo Jiping Zhang Keng Suan Yeo Qizhou Lian Fei Xie Eileen Khia Way Tan Dorothée Caille Oi Lian Kon Manuel Salto-Tellez Paolo Meda Sai Kiang Lim | 2008 | Stem Cell Research2008，，1： | 1 |
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