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| 1 | Role of liver transplantation in the management of hepatoblastoma in the pediatric population显示文摘Hepatoblastoma(HB) is the most common primary liver tumor in children and accounts for two-thirds of all malignant liver neoplasms in the pediatric population. For patients with advanced HB(unresectable or unresponsive to chemotherapy), combined treatment with chemotherapy and liver transplantation is an excellent option. The etiology of HB is mostly obscure because of its extreme rarity although some inherited syndromes and very low birth weight have been associated with it. The prognosis for children with HB has significantly improved in the past three decades thanks to advancements in chemotherapy, surgical resection and postoperative care. In 2002 a surgical staging system called pretreatment extent of disease(PRETEXT) was designed to allow a universal, multidisciplinary approach to patients with HB. Between one-third to two-thirds of patients initially present with unresectable tumors or distant metastases, but up to 85% of these tumors become operable after neoadjuvant chemotherapy. Patients with PRETEXT categories 1, 2, and some 3 are referred for neoadjuvant chemotherapy followed by surgical resection with the goal of complete tumor removal. Classic treatments regimens include a combination of cisplatin, fluorouracil, and vincristine or cisplatin and doxorubicin. Liver transplantation is the only treatment option for unresectable HB. In 2010 the pediatric end-stage liver disease, a pediatric-specific scoring system that determines a patient's ranking on the liver transplant list, began to award additional 'exception' points for patients with HB. We analyzed the Standard Transplant Analysis and Research dataset to assess the impact of changes in exception point criteria for HB on outcomes after liver transplantation at Texas Children's Hospital in Houston, Texas. We found that patients who were listed for transplantation with current HB exception criteria experienced a shorter waitlist time but survival was similar between the two eras. | Saira Khaderi Jacfranz Guiteau Ronald T Cotton Christine O'Mahony Abbas Rana John A Goss | 2014 | World Journal of Transplantation2014,4,4: | 23 |
| 2 | Geoclimatic factors influence the population genetic connectivity of Incarvillea arguta(Bignoniaceae)in the Himalaya-Hengduan Mountains biodiversity hotspot显示文摘Geoclimatic factors related to the uplift of the Himalaya and the Quaternary climatic oscillations in fluence the population genetic connectivity in the Himalaya-Hengduan Mountains(HHM)biodiversity hotspot.Therefore,to explore the relative roles played by these two factors,we examined the population dynamics and dispersal corridors of Incarvillea arguta(Royle)Royle incorporating ensemble species distribution modelling(SDM).Thirty-seven populations were genotyped using plastid chloroplast DNA and low copy nuclear gene(ncpCS)sequences.Phylogeographic analysis was carried out to reveal the genetic structure and lineage differentiation.Ensemble SDMs were carried out for distributional change in the last glacial maximum,present,and future.Finally,the least cost path method was used to trace out possible dispersal corridors.The haplotypes were divided into four clades with strong geographical structure.The late Miocene origin of I.arguta in the western Himalaya ca.7.92 Ma indicates lineage diversification related to the uplift of the HHM.The variability in habitat connectivity revealed by SDM is due to change in suitability since the Pleistocene.A putative dispersal corridor was detected along the drainage systems and river valleys,with strong support in the eastern Hengduan Mountains group.Our results support the signature of geoclimatic influence on population genetic connectivity of I.arguta in the HHM.We proposed that the major drainage systems might have assisted the rapid dispersal of isolated riverine plant species I.arguta in the HHM.The population genetic connectivity,using the fine-tuned ensemble SDMs,enables scientists and policymakers to develop conservation strategies for the species gene pool in the HHM biodiversity hotspots. | Santosh Kumar Rana Dong Luo Hum Kala Rana Alexander Robert O'Neill Hang Sun | 2021 | Journal of Systematics and Evolution2021,59,1: | 3 |
| 3 | A comparative study: conventional preparation and ThinPrep 2000 in respiratory cytology 显示文摘 | Rana DN O'Donnell M Malkin A | 2001 | Cytopathology2001,12,6: | 1 |
| 4 | Applying Conflict Management Strategies in BDI Agents for Resource Management in Computational Grids 显示文摘 | RANA O F WINIKOFF M | 2002 | Australian Computer Science Communications2002,24,1: | 1 |
| 5 | UDDIe: An extended registry for Web service显示文摘 | SHAIKHALI A RANA O F AL-ALI R J | 2003 | IEEE Computer Society2003,7,3: | 1 |
| 6 | Ontology-based semantic matchmaking approach显示文摘 | Shu G Rana O F Avis N J ct al | 2007 | Advances in Engineering Software2007,,: | 1 |
| 7 | G-QoSM: Grid service discovery using QoS properties显示文摘 | AL-ALI R RANA O WALKER D | 2003 | Computing and Informaties Journal Special Issue on Grid Computing2003,,: | 1 |
| 8 | CloudPick:aframework for QoS-aware and ontology-based servicedeployment across clouds显示文摘 | Dastjerdi A V Garg S K Rana O F | 2014 | Software:Practice and Experience2014,,: | 1 |
| 9 | G-QoSM:grid service discovery using QoS properties显示文摘 | Al-Ali R Rana O Walker D | 2002 | Computing and Informatics Journal Special Issue on Grid Computing2002,21,4: | 1 |
| 10 | Regulation of nerve growth factor in the heart:the role of the calcineurin-NFAT pathway显示文摘 | Rana O R Saygili E Meyer C | 2009 | J Mol Cell Cardiol2009,46,4: | 1 |
| 11 | Losartan prevents stretch-induced electrical remodeling in cul- tured atrial neonatal myocytes 显示文摘 | SAYGILI E RANA O R REUTER H | 2007 | Am I Physiol Heart Circ Physiol2007,292,6: | 1 |
| 12 | Polymer nanocom posiles based on functionalized carbon nanotubes显示文摘 | Sahoo N O Rana S Cho J W | 2010 | Progress in Polymer Science2010,35,7: | 1 |
| 13 | The convergence of clouds,grids,and autonomics显示文摘 | Germain-Renaud C Rana O F | | 0,,06: | 1 |
| 14 | The role of matrix metalloproteinases in ulcerative keratolysis associated with perioperative diclofenac use显示文摘 | O'Brien TP Li QJ Sauerburger F Reviglio VE Rana T Ashraf MF | 2001 | Ophthalmology2001,108,4: | 1 |
| 15 | Transfusion-related acute lung injury in the critically ill: prospective nested case-control study显示文摘 | Gajic O Rana R Winters JL | 2007 | Am J Respir Crit Care Med2007,176,9: | 1 |
| 16 | Performance evalua- tion of semantic registries: OWLJessKB and in- stanceStore 显示文摘 | Ludwig S A Rana O F | 2008 | Service Oriented Computing and Applications2008,2,1: | 1 |
| 17 | Transfusion-related acute lung injury in the critically ill: prospective nested case-control study显示文摘 | Gajic O Rana R Winters JL | 2007 | Am J Respir Crit Care Med2007,176,9: | 1 |
| 18 | G-QoSM: grid service discovery using QoS properties显示文摘 | A1-Ali R Rana O Walker D | 2002 | Computing and Information Journal2002,21,4: | 1 |
| 19 | Cloud computing for the architecture,engineering & construction sector:requirements,prototype & experience显示文摘 | BEACH T H RANA O F REZGUI Y | 2013 | Journal of Cloud Computing2013,2,1: | 1 |
| 20 | Reputation-basedsemantic service discovery显示文摘 | Majithia S Ali A S Rana O F | 2006 | Concurrency andComputation:Practice&Experience2006,18,8: | 1 |