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| 1 | 短期针刺足三里对脂多糖诱导的大鼠急性肺损伤的预防作用(英文)显示文摘目的:研究短期手法针刺足三里治疗对脂多糖诱导的实验性大鼠急性肺损伤的预防作用。方法:根据是否进行脂多糖刺激及采用的针刺方法的不同,将32只 Wistar 大鼠随机分为4组,即正常对照组、模型组、假针刺组和针刺组,每组8只。假针刺组和针刺组大鼠行手法针刺治疗,连续治疗4 d,每次 5 min。第4天针刺后采用脂多糖刺激诱导大鼠急性肺损伤。第5天,收集外周血、支气管肺泡灌洗液和骨髓等进行白细胞计数。结果:血细胞计数和支气管肺泡灌洗液细胞计数提示,针刺可减轻急性肺损伤大鼠的炎性反应,假针刺也有轻微的效果。正常对照组和模型组大鼠无明显的炎性反应。与正常对照组比较,模型组肺泡灌洗液中细胞计数增加;与假针刺组比较,针刺组肺泡灌选液中细胞计数减少,但差异没有统计学意义。结论:预防性手法针刺足三里可减轻脂多糖诱导的大鼠急性肺损伤,但其相关免疫机制仍待进一步的研究。 | Arthur de Sá FERREIRA Januário Gomes Mourāo e LIMA Tatiana Pereira Teixeira FERREIRA Camila Madeira Tavares LOPES Rubens MEYER | 2009 | 中西医结合学报2009，7，10： | 21 |
| 2 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 3 | A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration显示文摘Age-related macular degeneration(AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040.Genetics,age,diabetes,gender,obesity,hypertension,race,hyperopia,iris-color,smoking,sun-light and pyroptosis have varying roles in AMD,but oxidative stress-induced inflammation remains a significant driver of pathobiology.Eye is a unique organ as it contains a remarkable oxygengradient that generates reactive oxygen species(ROS) which upregulates inflammatory pathways.ROS becomes a source of functional and morphological impairments in retinal pigment epithelium(RPE),endothelial cells and retinal ganglion cells.Reports demonstrated that hydrogen sulfide(H_2S) acts as a signaling molecule and that it may treat ailments.Therefore,we propose a novel hypothesis that H_2S may restore homeostasis in the eyes thereby reducing damage caused by oxidative injury and inflammation.Since H_2S has been shown to be a powerful antioxidant because of its free-radicals' inhibition properties in addition to its beneficial effects in age-relatedconditions,therefore,patients may benefit from H_2S salubrious effects not only by minimizing their oxidant and inflammatory injuries to retina but also by lowering retinal glutamate excitotoxicity. | Akash K George Mahavir Singh Rubens Petit Homme Avisek Majumder Harpal S SANDhu Suresh C Tyagi | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 4 | 恶性青光眼及其治疗显示文摘本文详细叙述了恶性青光眼的定义、发病率、发病机制、超声生物显微镜的检查、诊断和治疗。 | Ruben,S 王学敏 | 1998 | 国外医学(眼科学分册)1998，22，2： | 3 |
| 5 | Differential effect of algal and soil-derived dissolved organic matter on alpine lake bacterial community composition and activity显示文摘 | PEREZM T RUBEN S | 2006 | Limnol Oceanogr2006，51，6： | 1 |
| 6 | Differential effect of algal and soil derived dissolved organic matter on alpine lake bacterial community composition and activity显示文摘 | Perezm T Ruben S | 2006 | Limonl Oceanogr2006，51，6： | 1 |
| 7 | Data Balancing for Efficient Training of Hybrid ANN/HMM Automatic Speech Recognition Systems显示文摘 | ANA I G RUBEN S U | 2011 | IEEE Transactions on Audio Speech and Language Processing2011，19，3： | 1 |
| 8 | Temperature sensitivity and pressure resistance of mushroom polyphenoloxidase显示文摘 | Weemaes C Rubens P De Cordt S | 1997 | J Food Science1997，62，2： | 1 |
| 9 | Sequence analysis of expressed sequence tags from an ABA-treated cDNA library identifies stress response genes in the moss Physcomitrella patterns显示文摘 | Machuka J Bashiardes S Ruben E Spooner K Cuming A Knight C Cove D | 1999 | Plant Cell Physiol1999，40，4： | 1 |
| 10 | Elastic management of Web server dusters on distributed virtual infrastructures显示文摘 | Rafael Moreno-Vozmediano Ruben S Montero Ignacio M Llorente | 2011 | Concurrency and Computation:Practice & Experience2011，23，13： | 1 |
| 11 | Sternal displacement with different loads显示文摘 | RUBEN H JOHANSEN S H | 1966 | Acta Anaesthesiol Scand1966，10，1： | 1 |
| 12 | Synthesis spectral and electrochemical properties of Al(Ⅲ)and Zn (Ⅱ)complexes with flavonoids显示文摘 | RUBENS F V D S WAGNER F D G | 2005 | Spectrochimica Acta Part A2005，61，： | 1 |
| 13 | Regularization methods for ill- posed problems in multiple Hilbert scales 显示文摘 | Gisela M L Ruben S O | 2012 | Inverse Problems2012，28，5： | 1 |
| 14 | The effect of intensity-modulated radiotherapy on radiation-induced second malignancies显示文摘 | Ruben JD Davis S Evans C | 2008 | Int J Radiat Oncol Biol Phys2008，70，5： | 1 |
| 15 | A simple and effective iterated greedy algo- rithm for the permutation flow shop scheduling problem 显示文摘 | RUBEN R THOMAS S | 2007 | Euro- pean Journal of Operational Research2007，177，3： | 1 |
| 16 | T-ceUlymphoproliferative disorder following mycophenolate treatment formyasthenia gravis 显示文摘 | DUBAL D B MUELLER S RUBEN B S | 2009 | Muscle Nerve2009，39，6： | 1 |
| 17 | Outbreaks of clinical mastitis caused by Trichosporon beigelii in dairy herds 显示文摘 | Ruben N G David J W Sharon A S | 2001 | J Am Vet Med Assoc2001，218，2： | 1 |
| 18 | 'Land rental market, off-farmemployment and agricultural production in Southeast China: A plot-level case study' 显示文摘 | Feng S Y Heerink N Ruben R | 2010 | China Economic Review2010，21，4： | 1 |
| 19 | Employee ownership:A conceptual model of process and effects显示文摘 | Pierce J L Ruben feld SA and Morgan S | 1991 | Academy of Management Review1991，16，1： | 1 |
| 20 | Use of coaxial gas jackets to stabilize taylor cones of volatile solutions and to induce particle-to- fiber transitions 显示文摘 | Gustavo L Ruben S Raffet VO | 2004 | Advanced Materials2004，16，2： | 1 |
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