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546篇 您的检索式:作者名="Randolph A"
    题名 作者 年代 出处 被引量
1Augmenting peripheral nerve regeneration using stem cells: A review of current opinion显示文摘Outcomes following peripheral nerve injury remain frustratingly poor. The reasons for this are multifactorial, although maintaining a growth permissive environment in the distal nerve stump following repair is arguably the most important. The optimal environment for axonal regeneration relies on the synthesis and release of many biochemical mediators that are temporally and spatially regulated with a high level of incompletely understood complexity. The Schwann cell(SC) has emerged as a key player in this process. Prolonged periods of distal nerve stump denervation, characteristic of large gaps and proximal injuries, have been associated with a reduction in SC number and ability to support regenerating axons. Cell based therapy offers a potential therapy for the improvement of outcomes following peripheral nerve reconstruction. Stem cells have the potential to increase the number of SCs and prolong their ability to support regeneration. They may also have the ability to rescue and replenish populations of chromatolytic and apoptotic neurons following axotomy. Finally, they can be used in non-physiologic ways to preserve injured tissues such as denervated muscle while neuronal ingrowth has not yet occurred. Aside from stem cell type, careful consideration must be given to differentiation status, how stem cells are supported following transplantation and how they will be delivered to the site of injury. It is the aim of this article to review current opinions on the strategies of stem cell based therapy for the augmentation of peripheral nerve regeneration.Neil G Fairbairn Amanda M Meppelink Joanna Ng-Glazier Mark A Randolph Jonathan M Winograd 2015World Journal of Stem Cells2015,7,1:12
2Analytical modeling of hammer impact for pile driving显示文摘Deeks A J Randolph M F 1993International Journal for Numerical and Analytical Methods in Geomechanics1993,17,5:2
3Analytical solution for pile hammer impact 显示文摘Take W A Valsangkar A J Randolph M F 1999Computers and Geotechnics1999,25,2:2
4Sub-micrometer-sized biodegradable particles of poly(L-lactic acid) via the gas antisolvent spray precipitation process 显示文摘RANDOLPH T W RANDOLPH A D MEBES M 1993Biotechnology Progress1993,23,9:1
5International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
6Tissue engineering cartilage显示文摘Ashiku SK Randolph MA Vacanti C A 0,,:1
7Cochrane review:Corti-costeroids for the prevention and treatment of post-extubation stridor in neonates,children and adults显示文摘Markovitz B Randolph A Khemani R G 0,,:1
8Axisymmetric time-domain transmitting boundaries显示文摘Deeks A J Randolph M F 1994Journal of Engineering Mechanics1994,120,1:1
9International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
10Axisymmetric Time-domain Transmitting Boundaries 显示文摘Deeks A J RandolPh M F 1994Journal of Engineering Mechanics ASCE1994,120,1:1
11Centrifuge modelling of pipe piles in sand under axial loads 显示文摘NICOLA A D E RANDOLPH M F 1999Geotechnique1999,49,3:1
12International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
13International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics 显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
14Total thyroidectomy is associated with increased risk of complications for low- and high- volume surgeons显示文摘Hauch A AI-Qurayshi Z Randolph G 2014Ann Surg Oncol2014,21,12:1
15International pediatric sepsis consensus conference:definitions for sepsis and organ dys- function in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
16显示文摘Tavana A Randolph A D 1989AIChE1989,35,10:1
17Axisymmetric time-domain transmitting boundaries显示文摘Deeks A J Randolph M F 1994Journal of Engineering Mechanics1994,120,1:1
18Sample preparation technique for artificially cemented soils显示文摘ISMAIL M A JOER H A RANDOLPH M F 2000Geotechnieal Testing Journal2000,23,2:1
19International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics 显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
20International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
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